1. A computer-implemented method, comprising:
providing, from a computer having one or more processors, a localization interface for localizing an application, the localization interface including first context information for an interface of the application having a first editable portion and one or more non-editable portions of the application, wherein at least one of the one or more non-editable portions is non-text based;
receiving, at the computer and via the localization interface, a first localization edit for the first editable portion of the first context information;
receiving, at the computer and via the localization interface, an indicator message that indicates a selection of a particular non-editable portion of the one or more non-editable portions, the selection indicating that the particular non-editable portion is localizable;
providing, from the computer and in response to the indicator message, second context information for the interface of the application in the localization interface, the second context information having a second editable portion corresponding to the particular non-editable portion;
receiving, at the computer and via the localization interface, a second localization edit for the second editable portion of the second context information; and
compiling, at the computer, a localized version of the application based on the first and second localization edits.
2. The computer-implemented method of claim 1, wherein the indicator message includes a priority ranking indicative of an importance of localizing the particular non-editable portion.
3. The computer-implemented method of claim 2, wherein the priority ranking is one of a high priority, a medium priority, and a low priority.
4. The computer-implemented method of claim 1, wherein at least one of the first and second localization edits includes a modification of character, font, font style, text effect, spacing, or color corresponding to the second editable portion.
5. The computer-implemented method of claim 1, wherein at least one of the first and second localization edits includes a modification of the size, color, scaling ratio, shade, brightness, contrast, content, shadow, artistic effect, reflection settings, or bevel.
6. The computer-implemented method of claim 1, wherein the particular non-editable portion comprises an image.
7. The computer-implemented method of claim 1, wherein the particular non-editable portion is non-text based.
8. The computer-implemented method of claim 1, wherein the indicator message includes a localization comment corresponding to the particular non-editable portion, the localization comment comprising an explanation of the indication that the particular non-editable portion is localizable.
9. The computer-implemented method of claim 1, wherein the first context information is a snapshot based on the application.
10. The computer-implemented method of claim 9, wherein the indicator message includes a highlighted version of the snapshot based on the application.
11. A computing system, comprising:
one or more processors; and
a non-transitory computer-readable storage medium having a plurality of instructions stored thereon, which, when executed by the one or more processors, cause the one or more processors to perform operations comprising:
providing a localization interface for localizing an application, the localization interface including first context information for an interface of the application having a first editable portion and one or more non-editable portions of the application, wherein at least one of the one or more non-editable portions is non-text based;
receiving, via the localization interface, a first localization edit for the first editable portion of the first context information;
receiving, via the localization interface, an indicator message that indicates a selection of a particular non-editable portion of the one or more noneditable portions, the selection indicating that the particular non-editable portion is localizable;
providing, in response to the indicator message, second context information for the interface of the application in the localization interface, the second context information having a second editable portion corresponding to the particular non-editable portion;
receiving, via the localization interface, a second localization edit for the second editable portion of the second context information; and
compiling a localized version of the application based on the first and second localization edits.
12. The computing system of claim 11, wherein the indicator message includes a priority ranking indicative of an importance of localizing the particular noneditable portion.
13. The computing system of claim 12, wherein the priority ranking is one of a high priority, a medium priority, and a low priority.
14. The computing system of claim 11, wherein at least one of the first and second localization edits includes a modification of character, font, font style, text effect, spacing, or color corresponding to the second editable portion.
15. The computing system of claim 11, wherein at least one of the first and second localization edits includes a modification of the size, color, scaling ratio, shade, brightness, contrast, content, shadow, artistic effect, reflection settings, or bevel.
16. The computing system of claim 11, wherein the particular non-editable portion comprises an image.
17. The computing system of claim 11, wherein the particular non-editable portion is non-text based.
18. The computing system of claim 11, wherein the indicator message includes a localization comment corresponding to the particular non-editable portion, the localization comment comprising an explanation of the indication that the particular noneditable portion is localizable.
19. The computing system of claim 11, wherein the first context information is a snapshot based on the application.
20. The computing system of claim 19, wherein the indicator message includes a highlighted version of the snapshot based on the application.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
What we claim is:
1. Method of producing a non-aqueous injection formulation containing
(a) as active ingredient the free valnemulin base;
(b) optionally a stabiliser to protect against oxidising influences and
(c) likewise optionally a stabiliser to protect against microbial infestation; whereby the free valnemulin base is produced in situ from a salt form in a physiologically acceptable non-aqueous solvent or solvent mixture (i) and is stabilised by adding a further solvent (ii).
2. Preparation according to claim 1, in which 0.5 to 30% by weight of a salt of valnemulin in a physiologically acceptable non-aqueous solvent or solvent mixture (i) is released in situ whilst heating gently and adding an appropriate alkaline excipient.
3. Preparation according to claim 1 or 2, in which one or more solvents are used as the non-aqueous solvent or solvent mixture (i), these being selected from the series isopropyl myristate, semi-synthetic and synthetic esters of glycerol, or ethylene or propylene glycol with short-chained to medium-chained mono- or dicarboxylic acids, medium-chained to long-chained carboxylic acids with monovalent alcohols.
4. Preparation according to one of claims 1 to 3, in which a salt of valnemulin is suspended in a solvent in a concentration range of 50 to 99% by weight, and the free base of valnemulin is produced in situ using an appropriate alkaline excipient, whilst heating gently and stirring.
5. Preparation according to one of claims 1 to 5, whereby in order to physically stabilise the valnemulin base, an ester of medium-chained to long-chained carboxylic acids with monovalent alcohols, 1,2-O-isopropylidene glycerol, glycerol, ethanol, N,N-dimethylacetamide, benzyl benzoate or tetraethylene glycol is added as a stabilising solvent (ii).
6. Preparation according to one of claims 1 to 5, whereby the solvents (i) and (ii) are present in the end product in a ratio of ca. 70:15.
7. Preparation according to one of claims 1 to 5, whereby a salt of valnemulin is suspended in a solvent or solvent mixture (i), an appropriate alkaline excipient is added to the suspension whilst stirring and heating gently in a temperature range of ca. 50 to ca. 80 C. in order to effect in situ release of the valnemulin base, the resulting free base is absorbed by this solvent (i); after completion of this process, the two phases which are immiscible together, the aqueous and the non-aqueous phase, are separated from one another at a temperature of ca. 50 to ca. 80 C.; the separated non-aqueous phase, which now contains the free base of (I), is washed many times with water at room temperature and undergoes fresh phase separation at a temperature of ca. 50 to 80 C.; the non-aqueous phase is subsequently dried and volatile components are removed, and it is mixed with a solvent or solvent mixture from group (ii) to stabilise it
8. Oily, stabilised injection formulation containing as active ingredient the free valnemulin base; obtainable by a method according to one of claims 1 to 7.
9. Use of an injection formulation according to claim 8 in a method of treating infectious diseases of productive livestock or domestic animals.