1. A fishing lure, comprising:
a flexible elongate body member with first and second ends; and
a cupped tail member fixedly attached to said second end of said body member for moving between concave and convex configurations to create low frequency pulses.
2. The fishing lure as in claim 1 wherein said cupped tail member is constructed of a resilient plastic material for biasing said cupped tail member toward said concave configuration.
3. The fishing lure as in claim 1 further comprising a plurality of spaced apart rib members interconnecting an inner surface of said cupped tail member and said second end of said body member.
4. The fishing lure as in claim 3 wherein said rib members are constructed of a resilient plastic material for biasing said cupped tail member toward said concave configuration.
5. The fishing lure as in claim 3 wherein said fishing lure is a one-piece molded construction of a flexible and resilient plastic material.
6. The fishing lure as in claim 5 wherein said flexible and resilient plastic material includes a scent for attracting fish.
7. The fishing lure as in claim 1 wherein said body member is impregnated with a scent for attracting fish.
8. The fishing lure as in claim 1 wherein said cupped tail member is impregnated with a scent for attracting fish.
9. The fishing lure as in claim 1 wherein said cupped tail member is at said concave configuration when pulled through water at a low rate of travel and is at said convex configuration when pulled through water at a high rate of travel.
10. The fishing lure as in claim 1 wherein said body member is worm-shaped.
11. A fishing lure, comprising:
a flexible worm-shaped body member with first and second ends; and
a hollow frustospherical tail member fixedly attached to said second end of said body member for moving between concave and convex configurations, wherein said movement from said concave configuration to said convex configuration creates a low frequency pulse.
12. The fishing lure as in claim 11 wherein said tail member is constructed of a resilient plastic material for biasing said tail member toward said concave configuration.
13. The fishing lure as in claim 11 further comprising a rib member connecting said body member to an inner surface of said tail member for biasing said tail member toward said concave configuration.
14. The fishing lure as in claim 11 further comprising a plurality of rib members connecting said body member to an inner surface of said tail member for biasing said tail member toward said concave configuration.
15. The fishing lure as in claim 14 wherein said fishing lure is a one-piece molded construction of a flexible and resilient plastic material.
16. The fishing lure as in claim 15 wherein said flexible and resilient plastic material is worm-colored.
17. The fishing lure as in claim 15 wherein said flexible and resilient plastic material includes a scent for attracting fish.
18. The fishing lure as in claim 17 wherein said flexible and resilient plastic material is worm-colored.
19. The fishing lure as in claim 18 wherein said tail member is at said concave configuration when pulled through water at a low rate of travel and is at said convex configuration when pulled through water at a high rate of travel.
20. The fishing lure as in claim 11 wherein said tail member is at said concave configuration when pulled through water at a low rate of travel and is at said convex configuration when pulled through water at a high rate of travel.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound of formula (I)
and acid-addition salts thereof with physiologically acceptable inorganic and organic acids.
2. A compound according to claim 1, characterized in that the physiologically acceptable inorganic or organic acid is selected from the group comprising hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid, nitric acid, acetic acid, ascorbic acid, oxalic acid, succinic acid, maleic acid, fumaric acid, tartaric acid, methanesulfonic acid, tannic acid and benzoic acid.
3. A method for preparing the compound of formula (I):
and the physiologically acceptable acid-addition salts thereof, characterized in that morpholin-4-yl acetic acid is reacted with 4-amino-2,6-dimethylphenol according to the following scheme:
in the presence of a suitable solvent, and optionally, the compound thus obtained is converted into a physiologically acceptable acid-addition salt thereof.
4. A method according to claim 3, characterized in that morpholin-4-yl acetic acid is reacted with 4-amino-2,6-dimethylphenol in the presence of a suitable coupling agent.
5. A method according to claim 4, characterized in that the coupling agent is N,N\u2032-dicyclohexylcarbodiimide.
6. A method according to any one of claims 3 to 5, characterized in that morpholin-4-yl acetic acid is reacted in the form of hydrochloride salt and in the presence of a suitable base.
7. A method according to claim 6, characterized in that the base is 4-dimethylaminopyridine.
8. A method according to any one of claims 3 to 7, characterized in that the solvent is a dipolar aprotic organic solvent.
9. A method according to claim 8, characterized in that the dipolar aprotic organic solvent is dichloromethane.
10. A pharmaceutical composition, characterized in that it comprises an effective dose of a compound of formula (I):
or of a physiologically acceptable acid-addition salt thereof, and at least one pharmaceutically acceptable inert ingredient.
11. A method of treatment in which an effective amount of a compound of formula (I):
or of a physiologically acceptable acid-addition salt thereof, is administered to a patient suffering from a febrile state or pain.