1. A compound of formula (I):
wherein Ar is an unsubstituted or substituted phenyl, naphthyl, pyridyl, pyrymidinyl, furyl, thiophene, quinoline, or pyrrolyl.
2. The compound of claim 1 further comprising a counter ion wherein the counter ion is selected from the group consisting of X\u2550BF4, Cl, PF6, BPh4, and RBF3.
3. The compound of claim 1, wherein the Ar is substituted phenyl.
4. The compound of claim 1, wherein Ar is phenyl group substituted with a substituent selected from the group consisting X, RXn, RO, and NO2, wherein R can be a substituted or unsubstituted branched or straight chain alkyl, X can be a halogen or pseudohalogen, and n is 1-3.
5. The compound of claim 1, wherein the Ar is selected from the group consisting of:
6. A composition comprising the compound of formula (I) and an additive, wherein the additive is selected from the group consisting of tetraalkyl ammonium salt, brine, and combinations thereof.
7. A method for asymmetric hydration of an activated aldehyde comprising contacting the aldehyde with a proton donor and a compound of formula
wherein the Ar is an unsubstituted or substituted phenyl, naphthyl, pyridyl, pyrymidinyl, furyl, thiophene, quinoline, or pyrrolyl;
and wherein the aldehyde undergoes asymmetric hydration to form a respective carboxylic acid of the enal.
8. The method of claim 7, wherein Ar is phenyl group substituted with a substituent selected from the group consisting X, RXn, RO, and NO2, wherein R can be a substituted or unsubstituted branched or straight chain alkyl, X can be a halogen or pseudohalogen, and n is 1-3.
9. The method of claim 7, wherein the aldehyde is an enal.
10. The method of claim 9, wherein the enal is a \u03b1,\u03b1-dichloro aldehyde or an \u03b1-chloro \u03b1-fluoro aldehyde.
11. The method of claim 7, wherein the aldehyde is selected from the group consisting of:
12. The method of claim 7 wherein, the asymmetric hydration results in an enantiomeric excess of the respective \u03b1-deuterio carboxylic acid, \u03b1-deuterio-\u03b1-chloro carboxylic acid or \u03b1-deuterio-\u03b1-fluoro carboxylic acid.
13. The method of claim 7 further comprising contacting the aldehyde with brine.
14. A method for asymmetric hydration of a drug analog comprising contacting the drug analog with a proton donor and a compound of formula
wherein the Ar is a an unsubstituted or substituted phenyl, naphthyl, pyridyl, pyrymidinyl, furyl, thiophene, quinoline, or pyrrolyl;
and wherein the drug analog includes at least one target aliphatic or functional group for asymmetric hydration to form the acid of the drug analog.
15. The method of claim 11, wherein Ar is phenyl group substituted with a substituent selected from the group consisting X, RXn, RO, and NO2, wherein R can be a substituted or unsubstituted branched or straight chain alkyl, X can be a halogen or pseudohalogen, and n is 1-3.
16. The method of claim 14, wherein the functional group is an activated aldehyde.
17. The method of claim 16, wherein the aldehyde is an enal.
18. The method of claim 17, wherein the enal is a \u03b1,\u03b1-dichloro aldehyde or an \u03b1-chloro \u03b1-fluoro aldehyde.
19. The method of claim 16, wherein the aldehyde is selected from the group consisting of:
20. The method of claim 14 wherein the drug analog is an \u03b1-fluoroenal and the asymmetric hydration forms an \u03b1-fluoro carboxylic acid.
21. The method of claim 14 wherein the asymmetric hydration results in an enantiomeric excess of the respective drug analog.
22. A method for asymmetric incorporation of an \u03b1-deuteron in an activated aldehyde comprising contacting the aldehyde with D2O and a compound of formula
wherein the Ar is an unsubstituted or substituted phenyl, naphthyl, pyridyl, pyrymidinyl, furyl, thiophene, quinoline, or pyrrolyl;
and wherein the aldehyde incorporates an \u03b1-deuteron.
23. The method of claim 22, wherein the aldehyde is an enal.
24. The method of claim 23, wherein the enal is a \u03b1,\u03b1-dichloro aldehyde or an \u03b1-chloro \u03b1-fluoro aldehyde.
25. The method of claim 22, wherein the aldehyde is selected from the group consisting of:
26. The method of claim 22, wherein Ar is phenyl group substituted with a substituent selected from the group consisting X, RXn, RO, and NO2, wherein R can be a substituted or unsubstituted branched or straight chain alkyl, X can be a halogen or pseudohalogen, and n is 1-3.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A light guide configured for positioning proximate to a light emitter in an electronic device; said light guide comprising:
a first prism having a first position in relation to said light emitter; said first prism having a first boundary defined by a first length and a first angle in relation to a plane normal to a surface of said light emitter; and,
a second prism having a second position in relation to said light emitter; said second prism having a second boundary defined by a second length and a second angle in relation to said plane;
wherein said first position is closer to said light emitter than said second position and said second angle is less than said first angle.
2. The light guide of claim 1 wherein said first angle is between about one degree and about eighty degrees.
3. The light guide of claim 1 wherein said first angle is about forty degrees.
4. The light guide of claim 1 wherein said first angle is between about thirty degrees and about fifty degrees.
5. The light guide of claim 1 wherein said second angle is between about one degree and about eighty degrees.
6. The light guide of claim 1 wherein said second angle is about twenty degrees.
7. The light guide of claim 1 wherein said second angle is between about ten degrees and about thirty degrees.
8. The light guide of claim 1 wherein said second angle is different than said first angle.
9. The light guide of claim 1 further comprising:
a third prism having a third position in relation to said light emitter; said third prism having a third boundary defined by a third length and a third angle in relation to said plane;
wherein said second position is closer to said light emitter than said third position and said third angle is less than said second angle.
10. The light guide of claim 1 comprising a plurality of additional prisms; each of said prisms being substantially square in shape arranged in a grid; each of said additional prisms having surfaces defined by additional lengths and additional angles in relation to said plane, each decreasing in size according to a distance from said light emitter.
11. The light guide of claim 1 wherein at least one of said prisms is a pyramid shape.
12. The light guide of claim 11 wherein said pyramid shape is one of a tetrahedron, a square pyramid, and a pentagonal pyramid.
13. The light guide of claim 11 wherein said pyramid shape has two pairs of sides; each said side in each said pair being of the same length; each of said pairs having different lengths.
14. The light guide of claim 1 wherein said first prism is conical and said second prism is a concentric annular prism surrounding said first prism.
15. The light guide of claim 1 wherein said first position centers said first prism in relation to said light emitter.
16. The light guide of claim 1 wherein said first position places said first prism off center in relation to said light emitter.
17. An electronic device comprising:
a light emitter;
a first prism having a first position in relation to said light emitter; said first prism having a first surface boundary defined by a first length and a first angle in relation to emitted light from a plane normal to a surface of said light emitter; said first prism configured to reflect at least a portion of said emitted light away from said first surface; and,
a second prism having a second position in relation to said light emitter; said second prism having a second boundary defined by a second length and a second angle in relation to said plane;
wherein said first position is closer to said light emitter than said second position and said second angle is less than said first angle.
an aperture proximate to said light emitter for transmitting light that is reflected from said first prism and said second prism.
18. The electronic device of claim 17 wherein said aperture is disposed on a key of a keyboard.
19. The electronic device of claim 17 wherein said aperture is configured for illuminating a surface of said electronic device and said device one of a cellular telephone, a handheld remote control unit, a garage door opener, a portable email paging device, a camera, a portable music player, a portable video player, a portable video game player, a handheld global positioning system (GPS) device, a keyboard for a desktop computers, a video game control pad.
20. The electronic device of claim 17 wherein said aperture is configured for a backlight of a display on said electronic device.