I claim:
1. A device for displaying wall and floor covering arrangements for selection by a purchaser comprising:
a frame assembly having a bottom, a plurality of upstanding walls secured to said bottom, said walls having a top and being interconnected and sized to define rooms such that said assembly substantially simulates a scaled-down house;
a plurality of interchangeable wall covering display panels, each of said wall covering display panels having a pair of opposite side edges joined by a top edge, and having wall covering secured thereto; and,
a plurality of interchangeable floor covering display panels; and,
wherein the bottom of said frame assembly is transparent and wherein said frame assembly defines a cavity subjacent to the transparent bottom, the cavity being sized and configured to receive at least one of said floor covering display panels for viewing through the transparent bottom.
2. The device of claim 1 further comprising a plurality of exterior facade display panels for displaying an exterior facade.
3. The device of claim 1 further comprising a plurality of roofing display panels.
4. The device of claim 1 wherein the walls are transparent.
5. The device of claim 1 wherein said rooms having channel members secured adjacent said walls, said channel members defining slots sized to receive the edges of said wall covering display panels therein.
6. The device of claim 5 wherein each of said wall covering display panels comprise on at least one side one of paint, paper, vinyl, plastic and wood.
7. The device of claim 1 wherein the bottom of said frame assembly is transparent and wherein said frame assembly defines a cavity subjacent to the transparent bottom, the cavity being sized and configured to receive at least one of said floor covering display panels for viewing through the transparent bottom and as the floor of one of the rooms.
8. The device of claim 1 wherein said frame assembly defines a cavity superjacent the bottom, the cavity being sized and configured to receive at least one of said floor covering display panels for viewing as a floor of one of the rooms.
9. The device of claim 8 wherein said floor covering display panels comprise at least one of carpeting, linoleum, refractory, cork and wood.
10. The device of claim 1 further including data processing means for processing data corresponding to any one of the wall covering panels paired with any one of the floor covering panels to define wall and floor covering matching arrangements.
11. The device of claim 5 further comprising data processing means for processing data corresponding to any one of the wall covering panels paired with any one of the floor covering panels to define wall and floor covering matching arrangements.
12. The device of claim 11 wherein said wall covering is selected from the group consisting of paint, paper, or wood.
13. The device of claim 11 wherein the floor covering display panels comprise floor coverings selected from the group consisting of carpeting, linoleum, refractory, cork and wood.
14. The device of claim 1 wherein said lighting means includes a fluorescent light source, an incandescent light source, a natural light source, and switch means for selectively activating the light sources.
15. A device for displaying room wall and floor covering arrangements for selection by a purchaser, comprising:
a frame assembly having display panel support means for slidably receiving and supporting at least one display panel in a display condition, the frame assembly being configured to resemble, along with at least one supported display panel positioned in the display condition, at least one room; and
at least two surface covering display panels being mutually different in at least one appearance or composition characteristic, such at least one appearance or composition characteristic including at least one of color, pattern, material, texture, and geometrical composition.
16. The device of claim 15 wherein said at least two surface covering display panels each comprise one of a wall covering and a floor covering.
17. The device of claim 15 wherein said at least two surface covering display panels each comprise one of a wall covering, a floor covering and a roof covering.
18. The device of claim 15 wherein said frame assembly includes transparent floor and wall panels through which can be seen a surface covering display panel in the display condition, the transparent floor and wall panels simulating unadorned floor and wall surfaces of the at least one room.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A method of treating a subject having a brain A\u03b2 disorder or predisposition to a brain A\u03b2 disorder, comprising peripherally administering a compound that modulates production of A\u03b2 in a peripheral tissue, wherein said compound is an imatinib derivative displaying reduced protein kinase inhibition compared to imatinib wherein said imatinib derivative comprises imatinib para-diaminomethylbenzene or a pharmaceutically acceptable salt thereof.
2. The method of claim 1, wherein the brain A\u03b2 disorder is Alzheimer’s disease.
3. The method of claim 1, wherein said modulation comprises reducing production of A\u03b2 in said peripheral tissue.
4. The method of claim 1, wherein said peripheral tissue is liver.
5. (canceled)
6. The method of claim 1, wherein said imatinib para-diaminomethylbenzene is in the form of a mesylate salt.
7-8. (canceled)
9. A method, comprising:
a) assessing a subject for the presence of a brain A\u03b2 disorder or predisposition to a brain A\u03b2 disorder;
b) peripherally administering a compound that modulates production of A\u03b2, wherein said compound does not substantially penetrate the blood brain barrier, wherein said compound comprises imatinib para-diaminomethylbenzene or a pharmaceutically acceptable salt thereof; and;
c) after said administering of step b), assessing said subject for a brain A\u03b2 disorder or progression of a brain A\u03b2 disorder.
10. The method of claim 9, wherein said modulation of production of A\u03b2 comprises modulating production of A\u03b2 in the liver of said subject.
11. The method of claim 10, wherein said modulation comprises inhibition.
12. The method of claim 9, wherein said brain A\u03b2 disorder is Alzheimer’s disease.
13. The method of claim 9, wherein said compound comprises an inhibitor of a \u03b3-secretase activity.
14. The method of claim 9, wherein said assessing comprises one or more of a mental status evaluation, neuropsychological testing, or brain imaging.
15-16. (canceled)
17. The method of claim 9, wherein said compound further comprises a known therapeutic agent for treating, ameliorating, or reducing risk or severity of a brain A\u03b2-related disorder.
18. The method of claim 17, wherein said known therapeutic agent is selected from the group consisting of imatinib, cannabinoids, dimebom, prednisone, ibuprofen, naproxyn, indomethacin; statins, selective estrogen receptor molecules, antihypertensives, alpha-blockers, beta-blockers, alpha-beta blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, diuretics, NSAIDS, and antioxidants.
19. The method of claim 9, wherein said peripherally administering comprises orally administering.
20. A composition comprising imatinib para-diaminomethylbenzene or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
21. (canceled)
22. The composition of claim 20, wherein said composition further comprises a known therapeutic agent for treating, ameliorating, or reducing risk or severity of a brain A\u03b2-related disorder.
23. The composition of claim 22, wherein said known therapeutic agent is selected from the group consisting of imatinib, cannabinoids, dimebom, prednisone, ibuprofen, naproxyn, indomethacin; statins, selective estrogen receptor molecules, antihypertensives, alpha-blockers, beta-blockers, alpha-beta blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, diuretics, NSAIDS, and antioxidants.
24. The composition of claim 20, wherein said composition is configured for oral administration.