1. A process comprising:
a) introducing a feed comprising:
(i) a water-immiscible organic extractant;
(ii) water;
(v) at least one isomer of butanol; and
(vi) optionally a non-condensable gas
into a first distillation column,
wherein the first distillation column comprises a stripping section and optionally a rectifying section at an introduction point above the stripping section, the first distillation column having an operating temperature T1 and an operating pressure P1 in the stripping section;
wherein T1 and P1 are selected to produce a first bottoms stream and a first vaporous overhead stream, the first bottoms stream comprising the water-immiscible organic extractant and water and being substantially free of butanol, and the first vaporous overhead stream comprising water, butanol, optionally the extractant, and optionally the non-condensable gas;
b) introducing a water-immiscible organic entrainer to at least one process stream or vessel;
c) condensing the first vaporous overhead stream to produce a gas phase and recover a first mixed condensate;
wherein the first mixed condensate comprises:
(i) an organic phase comprising butanol, entrainer, and water; and
(ii) an aqueous phase comprising water and butanol; and
wherein the first mixed condensate comprises sufficient entrainer to provide phase separation of the organic and the aqueous phases;
d) introducing at least a portion of the aqueous phase to the first distillation column;
e) introducing a first portion of the organic phase into a second distillation column having at least a stripping section; and
f) operating the second distillation column to produce a second bottoms stream comprising butanol and wherein said bottoms stream is substantially free of water and entrainer, and a second vaporous overhead stream comprising butanol, entrainer, and water.
2. The process of claim 1, wherein the extractant is selected such that it (A) preferentially extracts butanol over water and (B) is separable from butanol by distillation; and the entrainer is selected such that it (C) has a higher vapor pressure than butanol and (D) is separable from butanol by distillation.
3. The process of claim 1, further comprising any one of steps:
g) introducing a second portion of the organic phase into the first distillation column; or
h) condensing the vaporous overhead stream from the second distillation column to recover a second condensate stream, and introducing at least a portion of the second condensate stream into the first mixed condensate; or
j) both steps g) and step h).
4. The process of claim 1, wherein the process stream or vessel of step (b) is selected from the feed stream, the first vaporous overhead stream, the first mixed condensate stream, the second condensate stream, the portion of the organic phase which is introduced into the second column, the vaporous overhead stream from the second distillation column, the first distillation column, the decanter, the upper section of the second distillation column, and combinations thereof.
5. The process of claim 1, further comprising the step of introducing water, steam, or a mixture thereof into the first distillation column.
6. The process of claim 1, further comprising the step of introducing at least a portion of the aqueous phase into a fermentation vessel.
7. The process of claim 1, wherein the process further comprises the step of introducing the bottoms stream from the first distillation column into a fermentation vessel.
8. The process of claim 1, wherein the process further comprises separating the bottoms stream from the first distillation column to obtain a bottoms aqueous phase comprising water and a bottoms organic phase comprising the extractant, introducing at least a portion of the bottoms organic phase into a fermentation vessel, and optionally introducing at least a portion of the bottoms aqueous phase into a fermentation vessel.
9. The process of claim 1, wherein the gas phase comprises entrainer, and the process further comprises condensing the gas phase to recover at least a portion of the entrainer and optionally introducing the recovered entrainer to the first mixed condensate.
10. The process of claim 9, wherein a non-condensable gas is present in the feed, the gas phase further comprises the non-condensable gas, and the process further comprises purging at least a portion of the gas phase comprising the non-condensable gas from the process.
11. The process of claim 1, wherein the non-condensable gas comprises carbon dioxide.
12. The process of claim 1, wherein the feed comprises an organic phase obtained from an extractive fermentation.
13. The process of claim 1, wherein the butanol concentration in the feed is from about 0.1 weight percent to about 40 weight percent, based on the weight of the feed.
14. The process of claim 1, wherein the entrainer comprises at least one hydrocarbon.
15. The process of claim 14, wherein said at least one hydrocarbon selected from the group consisting of pentane, hexane, hexene, cyclohexane, benzene, toluene, and xylene.
16. The process of claim 1, wherein the extractant comprises at least one solvent selected from the group consisting of C7 to C22 fatty alcohols, C7 to C22 fatty acids, esters of C7 to C22 fatty acids, C7 to C22 fatty aldehydes, C7 to C22 fatty amides, and mixtures thereof.
17. The process of claim 16, wherein the extractant comprises at least one solvent selected from the group consisting of C12 to C22 fatty alcohols, C12 to C22 fatty acids, esters of C12 to C22 fatty acids, C12 to C22 fatty aldehydes, C12 to C22 fatty amides, and mixtures thereof.
18. The process of claim 1, wherein the isomer of butanol is 1-butanol, 2-butanol, isobutanol, or mixtures thereof.
19. The process of claim 1, wherein the isomer of butanol is isobutanol.
20. The process of claim 1 wherein the butanol in the feed introduced into a first distillation column is produced by fermentation of corn or sugar cane.
21. The process of claim 1, wherein the feed further comprises ethanol and the second bottoms stream further comprises ethanol.
22. The process of claim 1 wherein there is a process to process heat exchange between the feed introduced to the first distillation column and the first bottoms stream.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A system for providing data analytics at a healthcare entity, the system comprising:
a computer system comprising one or more physical processors programmed with computer program instructions that, when executed, cause the computer system to:
receive data associated with a healthcare provider’s operation and performance from one or more data sources;
aggregate the data received from the one or more data sources;
process the aggregated data utilizing one or more data analytics models to generate healthcare analytics data; and
provide analytics and reporting based on the healthcare provider’s operation and performance.
2. The system of claim 1, wherein the received data is in a plurality of formats; and wherein the one or more physical processors are further programmed to:
convert the data received in the plurality of formats to a single format.
3. The system of claim 1, wherein the data analytics models include at least revenue cycle analytics, cash flow analytics, clinical analytics, supply chain analytics, and key performance indicator analytics.
4. The system of claim 3, wherein the cash flow analytics include at least one of operating cash and days cash on hand.
5. The system of claim 3, wherein the revenue cycle analytics include at least one of total claims in accounts receivable, average account receivable days outstanding, claim lifecycle, total claim adjustments, and denial rate.
6. The system of claim 3, wherein the clinical analytics include at least one of revenue by location, total clinical revenue, facility revenue, specialty revenue, physician revenue, and payer revenue.
7. The system of claim 6, wherein the revenue by location is displayed on map on a user interface, wherein each location is represented by a graphical representation and the relative size of the graphical representation corresponds the revenue for that location to provide insight into population served for expanding or sun setting service lines, facilities, etc.
8. The system of claim 3, wherein the key performance indicators are based on at least one of industry averages or target data provided by the user.
9. The system of claim 3, wherein the one or more data analytics models determine forecast and predict future trends utilizing predictive modeling tools.
10. The system of claim 9, wherein the predictive analytics combine clinical, supply chain and claims data to allow a healthcare provider to compare and contrast how changes in choice of medical devices, medicines, etc. impact both clinical outcomes and profits by physicians, specialties, and payers.
11. The system of claim 1, wherein the one or more physical processors are further programmed to:
generate and display a visualization of the provided analytics and reporting for display on a user interface.
12. The system of claim 1, wherein the one or more data analytics models track operating cash, revenue cycle, and clinical metrics against the healthcare provider’s internal targets or forecasts.
13. A computer implemented method for providing data analytics at a healthcare entity, wherein the method is implemented in a computer system comprising one or more physical processors programmed with computer program instructions that, when executed by the one or more physical processors, cause the computer system to perform the method, the method comprising:
receiving data associated with a healthcare provider’s operation and performance from one or more data sources;
aggregating the data received from the one or more data sources;
processing the aggregated data utilizing one or more data analytics models to generate healthcare analytics data; and
providing analysis and reporting based on the healthcare provider’s operation and performance.
14. The method of claim 13, wherein the received data is in a plurality of formats; and further comprising:
converting the data received in the plurality of formats to a single format.
15. The method of claim 13, wherein the data analytics models include at least revenue cycle analytics, cash flow analytics, clinical analytics, supply chain analytics, and key performance indicator analytics.
16. The method of claim 15, wherein the cash flow analytics include at least one of operating cash and days cash on hand.
17. The method of claim 15, wherein the revenue cycle analytics include at least one of total claims in accounts receivable, average account receivable days outstanding, claim lifecycle, total claim adjustments, and denial rate.
18. The method of claim 15, wherein the revenue by location is displayed on map on a user interface, wherein each location is represented by a graphical representation and the relative size of the graphical representation corresponds the revenue for that location.
19. The system of claim 18, wherein the revenue by location is displayed on map on a user interface, wherein each location is represented by a circle and the size of the circle corresponds the revenue for that location.
20. The method of claim 15, wherein the key performance indicators are based on at least one of industry averages or target data provided by the user.
21. The method of claim 15, wherein the one or more data analytics models determine forecast and predict future trends utilizing predictive modeling tools.
22. The system of claim 13, further comprising:
generating and display a visualization of the provided analytics and reporting for display on a user interface.