1. An image forming device that has a duplex printing function, and suspends execution of a printing operation to allow internal temperature to decrease when the internal temperature increases and reaches predetermined limit temperature at which toner in a developing unit is fusible, the image forming device comprising:
a storage unit configured to store, each time a print job is received, the received print job therein as a waiting print job;
a selection unit configured to select, from among a plurality of waiting print jobs, a print job that is estimated to cause the smallest increase in the internal temperature as a print job to be executed preferentially, based on printing conditions set on the respective waiting print jobs; and
a control unit configured to control execution order of the waiting print jobs so that the selected print job is executed preferentially.
2. The image forming device of claim 1, wherein
the selection unit calculates, for each of the waiting print jobs, a number of copies printable before the internal temperature reaches the limit temperature if the waiting print job is executed, based on a printing condition set on the waiting print job, and selects the print job to be executed preferentially based on the calculated number of copies printable.
3. The image forming device of claim 2, wherein
the storage unit further stores therein a plurality of printable number specification curves having been obtained for respective printing conditions, and each showing correspondence relationships between a number of printed copies and the internal temperature, and
the selection unit calculates the number of copies printable for each of the waiting print jobs, based on one of the printable number specification curves corresponding to a printing condition set on the waiting print job.
4. The image forming device of claim 2, wherein
the selection unit specifies at least one of the waiting print jobs corresponding to the largest number of copies printable, and selects the specified print job as the print job to be executed preferentially.
5. The image forming device of claim 4, wherein
when there are two or more waiting print jobs corresponding to the largest number of copies printable, the selection unit selects, from among the two or more waiting print jobs, a waiting print job corresponding to the smallest number of copies to be printed as the print job to be executed preferentially.
6. The image foaming device of claim 1, wherein
each of the printing conditions includes a condition indicating whether a print format is a simplex print format or a duplex print format, and
when the waiting print jobs include a waiting print job in the simplex print format and a waiting print job in the duplex print format, the selection unit selects the waiting print job in the simplex print format as the print job to be executed preferentially.
7. The image forming device of claim 6, wherein
each of the printing conditions includes a paper size, and
when the waiting print jobs are each in the simplex print format, the selection unit selects one of the waiting print jobs corresponding to the largest paper size as the print job to be executed preferentially.
8. The image forming device of claim 6, wherein
each of the printing conditions includes a paper thickness, and
when the waiting print jobs are each in the simplex print format, the selection unit selects one of the waiting print jobs corresponding to the greatest paper thickness as the print job to be executed preferentially.
9. The image forming device of claim 1, wherein
each of the printing conditions includes a condition indicating whether a print format is a color print format or a monochrome print format, and
when the waiting print jobs include a waiting print job in the color print format and a waiting print job in the monochrome print format, the selection unit selects the waiting print job in the monochrome print format as the print job to be executed preferentially.
10. The image forming device of claim 1 further comprising
a measurement unit configured to measure the internal temperature, wherein
when the measured internal temperature exceeds predetermined set temperature lower than the limit temperature, the selection unit selects, from among the waiting print jobs, the print job that is estimated to cause the smallest increase in the internal temperature as the print job to be executed preferentially, based on the printing conditions set on the respective waiting print jobs, and
when the measured internal temperature does not exceed the set temperature, the selection unit selects one of the waiting print jobs whose time of receipt is the earliest of all the waiting print jobs.
11. The image forming device of claim 1 further comprising
a monitoring unit configured to monitor an elapsed time since receipt of each print job stored as the waiting print job, wherein
the control unit controls the execution order so that, when the waiting print jobs include a waiting print job having been received more than a predetermined time period before, the waiting print job having been received more than the predetermined time period before is executed preferentially over the selected print job.
12. The image forming device of claim 1 further comprising
a count unit configured to count, for each print job stored as the waiting print job, a number of other print jobs executed after receipt of the stored print job, wherein
the control unit controls the execution order so that, when the number of the other print jobs executed after receipt of a given print job exceeds a predetermined number, the given print job is executed preferentially over the selected print job.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound selected from the group consisting of
14-O\u2014(((C1-6)Alkoxy-(C1-6)alkyl)-phenylsulfanyl)acetyl-mutilins,
14-O\u2014(((C1-6)Mono- or dialkylamino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O\u2014(((C1-6)Acylamino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Hydroxy-(C1-6)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Formyl-(C0-5)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Guanidino-imino-(C1-6)alkyl)-phenylsulfanyl acetyl-mutilins,
14-O-((Ureido-imino-(C1-6)alkyl)-phenylsulfanyl acetyl-mutilins,
14-O-((Thioureido-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Isothioureido-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Cyano-(C0-5)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Azido-(C0-5)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O\u2014(((C1-6)Acyloxy-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Benzoyloxy-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
wherein the phenyl-ring is optionally further substituted by up to four groups independently selected from halogen, (C1-6)alkyl, aryl, aryl(C1-6)-alkyl, (C1-6)alkoxy, (C1-6)alkoxy(C1-6)alkyl, halo(C1-6)alkyl, aryl(C1-6)alkoxy, hydroxy, nitro, cyano, azido, acyloxy, carbamoyl, mono- or di-N\u2014(C1-6)alkylcarbamoyl, (C1-6)-alkoxycarbonyl, aryloxycarbonyl, ureido, guanidino, (C1-6)alkylguanidino, amidino, (C1-6) alkylamidino, sulphonylamino, aminosulphonyl, (C1-6) alkylthio, (C1-6)-alkylsulphinyl, (C1-6) alkylsulphonyl, heterocyclyl, heteroaryl, heterocyclyl(C1-6)alkyl and heteroaryl(C1-6)alkyl, or two adjacent ring carbon atoms may be linked by a (C3-5) alkylene chain, to form a carbocyclic ring.
2. A compound according to claim 1 which is selected from the group consisting of
14-O\u2014(((C1-6)Alkoxy-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O\u2014(((C1-6-)Mono- or dialkylamino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Hydroxy-(C1-6)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Formyl-(C0-5)-alkyl)-phenylsulfanyl)-acetyl-mutilins,
14-O-((Guanidino-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl-mutilins,
3. A compound of formula (I)
wherein
n is 1 to 6;
X is oxygen or NR2 wherein R2 is hydrogen or linear or branched (C1-6)-alkyl, or hydroxy-(C1-6)alkyl or (C0-6)alkoxy-(C1-6)alkyl,
R1 is hydrogen, linear or branched (C1-6)-alkyl, mono- or dihalogenated (C1-6)-alkyl, amino(C1-6)-alkyl, hydroxy(C1-6)-alkyl, phenyl(C1-6)-alkyl, (C1-6)-alkylen, furanyl(C1-6)-alkyl, (C3-6)-cycloalkyl, and the corresponding ammonium salts, e.g. chlorides, or
R1 and R2 together with the nitrogen atom to which they are attached form a 5 to 7 membered heterocycle containing at least one nitrogen atom, or
XR1 is piperazinyl or morpholinyl.
4. A compound of formula (II)
wherein
n is 0 to 5,
Y is oxygen or NR3,
R3 is
X is oxygen, sulfur, NH or NR7;
or
together with a corresponding anion, e.g. chloride, R4, R5, R6, R7 are hydrogen, linear or branched C1-6alkyl or C3-8cycloalkyl,
R8 is C1-4alkyl.
5. A compound according to claim 4, wherein
Y is NR3, X is NR7, R3 is
and at least one of:
R4 and R7 together with the nitrogen atoms to which they are attached form a 5 to 7 membered heterocyclic ring containing at least 2 nitrogen atoms, whereas R5 and R6 are defined as in claim 4,
R5 and R6 together with the nitrogen atoms to which they are attached form a 5 to 7 membered heterocyclic ring containing at least 2 nitrogen atoms, whereas R4 and R7 are defined as in claim 4, and
R4 and R5 together with the nitrogen atoms to which they are attached form a 5 to 7 membered heterocyclic ring containing one or more nitrogen atoms, whereas R6 and R7 are defined as in claim 4.
6. A compound according to claim 5, wherein
Y is NR3, X is NR7, R3 is
R6 and R7 are defined as in claim 4,
R9 is hydrogen, linear or branched C1-6 alkyl or acyl, e.g. C1-6 acyl.
7. A compound according to claim 3, wherein said (CH2)n-group is in meta position in relation to the sulphur bound to the phenyl-ring.
8. A compound according to claim 3, wherein said (CH2)n-group is in ortho position in relation to the sulphur bound to the phenyl-ring, with the proviso that the phenyl-ring is further substituted by up to four groups independently selected from halogen, (C1-6)alkyl, aryl, aryl(C1-6)-alkyl, (C1-6)alkoxy, (C1-6)alkoxy(C1-6)alkyl, halo(C1-6)alkyl, aryl(C1-6)alkoxy, hydroxy, nitro, cyano, azido, acyloxy, carbamoyl, mono- or di-N\u2014(C1-6)alkylcarbamoyl, (C1-6)-alkoxycarbonyl, aryloxycarbonyl, ureido, guanidino, (C1-6)alkylguanidino, amidino, (C1-6) alkylamidino, sulphonylamino, aminosulphonyl, (C1-6) alkylthio, (C1-6)-alkylsulphinyl, (C1-6) alkylsulphonyl, heterocyclyl, heteroaryl, heterocyclyl(C1-6)alkyl and heteroaryl(C1-6)alkyl, or two adjacent ring carbon atoms may be linked by a (C3-5) alkylene chain, to form a carbocyclic ring.
9. A compound selected from the group consisting of
14-O-(3-Hydroxymethyl-phenylsulfanyl-acetyl-mutilin,
14-O-{3-(Aminoimino-methyl)-hydrazonomethyl-phenylsulfanyl-acetyl}-mutilin,
14-O-{3-((1-Piperazinoiminomethyl)-methylhydrazonomethyl-phenylsulfanyl}-acetyl-mutilin,
14-O-{3-(3-Ethyl-(2-ethylimino)-imidazolidin-1-ylimino)-methyl-phenylsulfanyl}-acetyl-mutilin,
14-O-{3-(1-Piperazinoiminomethyl)-hydrazonomethyl-phenylsulfanyl}-acetyl-mutilin,
14-O-{3-(2-Morpholin-4-yl-ethoxyimino)-methyl-phenylsulfanyl}-acetyl-mutilin,
14-O-3-{(2-Pyrrolidin-1-yl-ethoxyimino)-methyl-phenylsulfanyl}-acetyl-mutilin,
14-O-(3-Aminomethyl-phenylsulfanyl)-acetyl-mutilin,
14-O-(3-Allylaminomethyl-phenylsulfanyl)-acetyl-mutilin,
14-O-3-{(Furan-2ylmethyl)-amino-methyl}-phanylsulfanyl-acetyl-mutilin
14-O-(3-Cyclopropylaminomethyl-phenylsulfanyl)acetyl-mutilin.
10. A compound of claim 1, wherein the compound is in the form of a salt.
11. A compound of claim 1, wherein the compound is configured for pharmaceutical administration.
12. A method of treatment of a disease mediated by microbes which comprises administering to a subject in need of such treatment an effective amount of a compound of claim 1.
13. The method of claim 12, wherein the disease comprises acne.
14. The method of claim 12, wherein the disease mediated by microbes comprises one or both of a skin and soft tissue infection.
15. A pharmaceutical composition comprising a compound of claim 1, in association with at least one pharmaceutical excipient
16. A pharmaceutical composition according to claim 15 further comprising another pharmaceutically active agent.
17. A compound as defined in claim 1 for use in the preparation of a medicament for the treatment of acne.
18. A compound for use in the preparation of a medicament for the decolonization of bacterial carriers.
19. The compound of claim 18, wherein the compound comprises a compound of claim 1.