1. (canceled)
2. A power source, comprising:
a primary power source control circuit configured to couple a primary power source to an output;
a backup power source control circuit configured to couple a backup power source to the output; and
wherein at least one of the primary power source control circuit and the backup power source control circuit comprises a first transistor and a second transistor coupled in series between the output and the primary power source or the backup power source, respectively.
3. The power source of claim 2, wherein each of the primary power source control circuit and the backup power source control circuit respectively comprise the first transistor and the second transistor coupled in series.
4. The power source of claim 3, wherein a gate of the first transistor of the backup power source control circuit and a gate of the second transistor of the backup power source control circuit are each coupled to the first power source.
5. The power source of claim 3, the first transistor of the backup power source control circuit and the second transistor of the backup power source control circuit serially couple the backup power source to the output when the primary power source is disabled.
6. The power source of claim 2, wherein the primary power source is provided to the output when the enabled.
7. The power source of claim 2, further comprising a resistive element coupled between a node between the first transistor and the second transistor and a ground node.
8. The power source of claim 2, wherein a voltage level of the primary power source is greater than a voltage level of the backup power source.
9. A power source control circuit, comprising:
a first transistor coupled to a primary power source;
a second transistor coupled in series with the first transistor and to an output, wherein the first transistor and the second transistor are configured to couple the primary power source to the output responsive to the primary power source being enabled, and wherein the first transistor and the second transistor are configured to decouple the primary power source from the output responsive to the primary power source being disabled; and
a backup power source control circuit coupled to the output and to the primary power source.
10. The power source control circuit of claim 9, wherein a gate of the first transistor is coupled to the input.
11. The power source control circuit of claim 10, wherein a gate of the second transistor is coupled to the input.
12. The power source control circuit of claim 9, wherein the first transistor and the second transistor include respective inherent diodes.
13. The power source control circuit of claim 12, wherein the inherent diode of the first transistor and the inherent diode of the second transistor are coupled to have opposite polarities.
14. The power source control circuit of claim 9, wherein the backup power source control circuit is configured to provide a backup power source to the output when the primary power source is disabled.
15. The power source control circuit of claim 9, wherein the backup power source control circuit comprises a third transistor coupled in series with a fourth transistor, wherein the fourth transistor is coupled to the output.
16. The power source control circuit of claim 15, wherein a gate of the third transistor and a gate of the fourth transistor are coupled to the primary power source.
17. The power source control circuit of claim 15, wherein the third transistor is coupled to a backup power source.
18. A method, comprising:
receiving a power source at a primary power control circuit;
enabling a first transistor the power control circuit and a second transistor of the primary power control circuit responsive to the power source being enabled, wherein the first transistor is coupled in series with the second transistor;
disabling a backup power source control circuit responsive to the power source being enabled; and
providing the power source to an output via the enabled first transistor and the enabled second transistor.
19. The method of claim 18, further comprising disabling the first transistor and the second transistor responsive to the power source being disabled.
20. The method of claim 18, further comprising enabling a backup power source control circuit responsive to the power source being disabled.
21. The method of claim 20, further comprising providing a backup power source to the output responsive to the backup power source control circuit being enabled.
22. The method of claim 20, wherein enabling a backup power source control circuit comprises enabling a third transistor and a fourth transistor.
23. The method of claim 20, wherein the third transistor is coupled in series with the fourth transistor.
24. The method of claim 18, further comprising receiving a backup power source at the backup power source control circuit.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A radiohalogen-labeling reagent having the structure:
wherein
Hal is a radiohalide isotope selected from 123I, 124I, 125I, 131I, and 211At;
L is a linker selected from \u2014(C1-C12 alkylene)-C(O)NR\u2014(C1-C12 alkylene)-, \u2014(C1-C12 alkylene)-C(O)NR\u2014(C1-C12 alkylene)O\u2014, \u2014(C1-C12 alkylene)-C(O)NR\u2014(C1-C12 alkylene)-C(O)CH2\u2014, \u2014(C1-C12 alkylene)-C(O)N(R)\u2014, \u2014(C1-C12 alkylene)-C(O)NR\u2014(C2-C8 alkenylene)-, \u2014(C1-C12 alkylene)-C(O)NR\u2014(C2-C8 alkynylene)-, \u2014(C1-C12 alkylene)-C(O)NR(CH2CH2O)n\u2014, \u2014(C1-C12 alkylene)-C(O)\u2014, \u2014(C1-C12 alkylene)-C(O)NR(CH2CH2O)nCH2C(O)\u2014, and \u2014(C1-C12 alkylene)-C(O)NR(CH2CH2O)nCH2\u2014,
where n is 1 to 6, R is H, C1-C12 alkyl, or C6-C20 aryl, and
alkylene, alkenylene, alkynylene, alkyl, and aryl are optionally substituted with one or more groups selected from F, Cl, Br, I, \u2014CH3, \u2014CH2CH3, \u2014CH(CH3)2, \u2014CH2CH(CH3)2, \u2014CH2NH2, \u2014CH2CH2NH2, \u2014CH2CHCH2NH2, \u2014CH2CH(CH3)NH2, \u2014CH2OH, \u2014CH2OCH3, \u2014CH2CH2OH, \u2014CH2CH2OCH3, \u2014C(CH3)2OH, \u2014CH(OH)CH(CH3)2, \u2014C(CH3)2CH2OH, \u2014CH2CH2SO2CH3, \u2014CN, \u2014CF3, \u2014CO2H, \u2014COCH3, \u2014CO2CH3, \u2014CO2C(CH3)3, \u2014COCH(OH)CH3, \u2014CONH2, \u2014CONHCH3, \u2014CON(CH3)2, \u2014C(CH3)2CONH2, \u2014NO2, \u2014NH2, \u2014NHCH3, \u2014N(CH3)2, \u2014NHCOCH3, \u2014N(CH3)COCH3, \u2014NHS(O)2CH3, \u2014N(CH3)C(CH3)2CONH2, \u2014N(CH3)CH2CH2S(O)2CH3, \u2550O, \u2014OH, \u2014OCH3, \u2014OP(O)3, \u2014S(O)2N(CH3)2, \u2014S(O)3, \u2014SCH3, and \u2014S(O)2CH3; and
E is a reactive functional group selected from maleimide, thiol, amino, bromide, bromoacetamido, p-toluenesulfonate, iodide, hydroxyl, carboxyl, aldehyde, pyridyl disulfide, N-hydroxysuccinimide, azido, isocyanato, isothiocyanato, and phosphoramidite.
2. The radiohalogen-labeling reagent of claim 1 wherein E is maleimide.
3. The radiohalogen-labeling reagent of claim 2 having the formula:
where I is an iodine isotope selected from 123I, 124I, 125I, and 131I.
4. The radiohalogen-labeling reagent of claim 1 wherein E is N-hydroxysuccinimide.
5. The radiohalogen-labeling reagent of claim 4 having the formula:
where I is an iodine isotope selected from 123I, 124I, 125I, and 131I.