1. A device for treating a patient with type II diabetes comprising:
a gastric anchor movable between a first configuration sized and shaped for advancement through an esophagus into a selected region of a stomach of the patient and a second configuration sized and shaped for inhibiting distal movement of the gastric anchor through a pyloric sphincter of the patient;
a duodenal anchor coupled to the gastric anchor and movable between a first configuration sized and shaped for advancement through the esophagus, the stomach and the pyloric sphincter into a proximal region of a duodenum of the patient and a second configuration sized and shaped to inhibit proximal movement of the duodenal anchor through the pyloric sphincter; and
a substantially hollow sleeve coupled to the duodenal anchor and sized and shaped to extend through at least a proximal portion of the duodenum of the patient.
2. The device of claim 1 further comprising at least one flexible column coupling the gastric anchor to the duodenal anchor and configured for positioning across the pyloric sphincter of the patient.
3. The device of claim 1 wherein the gastric anchor defines an exterior wall housing an interior portion and an inlet in the exterior wall for delivering a fluid to the interior portion.
4. The device of claim 3 wherein the gastric anchor is configured for inflation by the fluid from a collapsed configuration to an inflated configuration.
5. The device of claim 1 wherein the gastric anchor has a substantially annular shape in the second configuration with an outer diameter of between about 30 mm to about 70 mm.
6. The device of claim 1 wherein the gastric anchor comprises an annular washer in the second configuration, the washer being foldable into the first configuration wherein the washer has a smaller diameter in the first configuration than the second configuration.
7. The device of claim 6 wherein the ring comprises a material having sufficient rigidity to withstand natural peristaltic forces of the patient and remain in the second configuration.
8. The device of claim 1 wherein the duodenal anchor defines an exterior wall housing an interior portion and an inlet in the exterior wall for delivering a fluid to the interior portion.
9. The device of claim 8 wherein the duodenal anchor is configured for inflation by the fluid from a collapsed configuration to an inflated configuration.
10. The device of claim 8 wherein the duodenal anchor has a substantially annular shape in the inflated configuration with an outer diameter of between about 20 mm to about 40 mm.
11. The device of claim 1 wherein the gastric anchor comprises an annular washer in the second configuration, the washer being foldable into the first configuration wherein the washer has a smaller diameter in the first configuration than the second configuration.
12. The device of claim 1 wherein the hollow sleeve has a length of about 1 to 3 feet.
13. The device of claim 1 wherein the hollow sleeve is sized and shaped to extend through the entire length of the duodenum of the patient.
14. The device of claim 11 wherein the hollow sleeve is sized and shaped to extend into a jejunum of the patient.
15. A method for treating a patient with type II diabetes comprising:
advancing a duodenal anchor through an esophagus, a stomach and a pyloric sphincter into a proximal region of a duodenum of the patient;
advancing a gastric anchor coupled to the duodenal anchor through the esophagus and into a distal region of the stomach of the patient;
expanding the duodenal anchor within the duodenum into an operative configuration that prevents proximal movement of the duodenal anchor through the pyloric sphincter;
expanding the gastric anchor within the stomach into an operative configuration that prevents distal movement of the gastric anchor through the pyloric sphincter; and
positioning a substantially hollow sleeve such that the sleeve extends from the duodenal anchor through at least a proximal portion of the duodenum of the patient.
16. The method of claim 15 wherein the expanding the duodenal anchor step is carried out by delivering a fluid into an interior of the duodenal anchor.
17. The method of claim 15 wherein the expanding the gastric anchor step is carried out by delivering a fluid into an interior of the gastric anchor and expanding the anchor.
18. The method of claim 15 further comprising coupling a proximal end of the hollow sleeve to the duodenal anchor.
19. The method of claim 15 wherein the hollow sleeve is positioned to extend through the entire length of the duodenum of the patient.
20. The method of claim 15 wherein the hollow sleeve is positioned to extend into the jejunum of the patient.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A sticking apparatus for manufacturing a laminate which is formed by laminating a substrate, an adhesive layer, and a support in this order by sticking the substrate and the support to each other through the adhesive layer, the sticking apparatus comprising:
a pair of plate members which sandwiches the laminate therebetween, wherein the pair of plate members includes respective press plates, each of which is formed of ceramic, wherein mutually facing surfaces of the respective press plates are formed such that flatness at a time of non-pressing is less than or equal to 1.0 \u03bcm; and
supporting members which support the plate members,
wherein the supporting member supporting at least one of the plate members is located in a form of a plurality of dots or lines adjacent to each other at regular intervals on the plate member.
2. The sticking apparatus according to claim 1, wherein the supporting member is provided in a plurality so as to be adjacent to each other at regular intervals.
3. The sticking apparatus according to claim 2, wherein the plurality of supporting members are provided in the vicinity of an outer peripheral portion of the plate member in a circular pattern so as to be adjacent to each other at regular intervals of 120\xb0, 90\xb0, 72\xb0, 60\xb0 or 45\xb0.
4. The sticking apparatus according to claim 3, wherein a supporting member is further provided at a center point of the circle.
5. The sticking apparatus according to claim 2, wherein the supporting member is provided with an adjusting member for pressure adjustment.
6. The sticking apparatus according to claim 2, wherein the supporting member is provided at a position distant from a center point of the plate member in a radial direction in a range of greater than or equal to 65% of a radius and less than or equal to 95% of the radius.
7. A sticking method for manufacturing a laminate which is formed by laminating a substrate, an adhesive layer, and a support in this order by sticking the substrate and the support to each other through the adhesive layer, the sticking method comprising:
supporting at least one plate member of a pair of plate members sandwiching the laminate therebetween by supporting members located in a form of a plurality of dots or lines adjacent to each other at regular intervals on the plate member, and pressing the plate members by the supporting members when sticking the substrate and the support to each other, wherein the pair of plate members includes respective press plates, each of which is formed of ceramic, wherein mutually facing surfaces of the respective press plates are formed such that flatness at a time of non-pressing is less than or equal to 1.0 \u03bcm.
8. The sticking method according to claim 7, wherein pressing forces of the supporting members pressing the plate members are adjusted such that a pressing force which is applied to the laminate becomes uniform.
9. The sticking method according to claim 8, wherein the difference between the maximum value and the minimum value of the pressure distribution of the pressing force which is applied to the pair of plate members be adjusted into a range of less than or equal to 700 kPa.