1. A method of fabricating a lapping carrier comprising;
defining at least one opening extending through a workpiece that is sized to receive a wafer; and
cryogenically tempering the workpiece to produce the lapping carrier, wherein cryogenically tempering the workpiece comprises subjecting the workpiece to a cryogenic temperature for a sufficient time to convert at least 70% of the crystalline structure of the workpiece to a martensite crystalline structure.
2. A method according to claim 1 wherein subjecting the workpiece to a cryogenic temperature comprises subjecting the workpiece to a plurality of thermal cycles with at least one thermal cycle conducted at a cryogenic temperature.
3. A method according to claim 1 wherein cryogencially tempering the workpiece comprises converting at least about 99% of the crystalline structure of the workpiece to the martensite crystalline structure.
4. A method according to claim 1 wherein forming the workpiece comprises punching the at least one opening therethrough.
5. A method according to claim 1 wherein forming the workpiece comprises polishing an edge of the at least one opening defined by the workpiece.
6. A method of fabricating a lapping carrier comprising:
cryogenically tempering a workpiece by subjecting the workpiece to a cryogenic temperature for a sufficient time to convert at least 70% of the crystalline structure of the workpiece to a martensite crystalline structure; and
forming at least one opening through the cryogenically tempered workpiece that is sized to receive a wafer.
7. A method according to claim 6 wherein cryogenically tempering the workpiece comprises subjecting the workpiece to a plurality of thermal cycles with at least one thermal cycle conducted at a cryogenic temperature.
8. A method according to claim 6 wherein cryogencially tempering the workpiece comprises converting at least about 90% of the crystalline structure of the workpiece to the martensite crystalline structure.
9. A method according to claim 6 wherein forming the at least one opening comprises punching the at least one opening through the cryogenically tempered workpiece.
10. A method according to claim 6 wherein forming the at least one opening comprises polising an edge of the at least one opening.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound which is:
and solvates, hydrates, tautomers, and pharmaceutically acceptable salts thereof.
2. A compound of claim 1 which is:
and solvates, hydrates, tautomers, and pharmaceutically acceptable salts thereof.
3. A compound of claim 1, which is:
and solvates, hydrates, tautomers, and pharmaceutically acceptable salts thereof.
4. A compound of claim 1, which is:
and solvates, hydrates, tautomers, and pharmaceutically acceptable salts thereof.
5. A pharmaceutical composition comprising a compound of claim 1; and a pharmaceutically acceptable carrier.
6. A method of treating a subject having a disorder ameliorated by antagonizing Adenosine A2a receptors in appropriate cells in the subject, which comprises administering to the subject a therapeutically effective dose of a compound of claim 1.
7. A method of preventing a disorder ameliorated by antagonizing Adenosine A2a receptors in appropriate cells in the subject, comprising administering to the subject a prophylactically effective dose of a compound of claim 1 either preceding or subsequent to an event anticipated to cause a disorder ameliorated by antagonizing Adenosine A2a receptors in appropriate cells in the subject.
8. The method of claim 6, comprising administering to the subject a therapeutically or prophylactically effective dose of the pharmaceutical composition of claim 5.
9. The method of claim 7, comprising administering to the subject a therapeutically or prophylactically effective dose of the pharmaceutical composition of claim 5.
10. The method of claim 6, wherein the disorder is a neurodegenerative disorder or a movement disorder.
11. The method of claim 6, wherein the disorder is selected from the group consisting of Parkinson’s Disease, Huntington’s Disease, Multiple System Atrophy, Corticobasal Degeneration, Alzheimer’s Disease, and Senile Dementia.
12. The method of claim 7, wherein the disorder is a neurodegenerative disorder or a movement disorder.
13. The method of claim 7, wherein the disorder is selected from the group consisting of Parkinson’s Disease, Huntington’s Disease, Multiple System Atrophy, Corticobasal Degeneration, Alzheimer’s Disease, and Senile Dementia.
14. The method of claim 6, wherein the disorder is Parkinson’s Disease.
15. The method of claim 6, wherein the disorder is addiction.
16. The method of claim 6, wherein the disorder is Attention Deficit Hyperactivity Disorder (ADHD).
17. The method of claim 6, wherein the disorder is depression.
18. The method of claim 6, wherein the disorder is anxiety.