1-43. (canceled)
44. A compound, which is
Name
Structure
N-3-fluoro-4-({6-(methyloxy)-7-(3-morpholin-4-ylpropyl)oxyquinolin-4-yl}oxy)phenyl-N\u2032-2-(4-fluorophenyl)ethylethanediamide
45-52. (canceled)
53. A pharmaceutical composition comprising a compound according to claim 44 and a pharmaceutically acceptable carrier.
54. A metabolite of the compound according to claim 44.
55. A method of modulating the in vivo activity of a kinase, the method comprising administering to a subject an effective amount of the compound according to claim 44.
56. The method according to claim 55, wherein modulating the in vivo activity of the kinase comprises inhibition of said kinase.
57. The method according to claim 55, wherein the kinase is at least one of c-Met, KDR, c-Kit, flt-3, and flt-4.
58. The method according to claim 57, wherein the kinase is c-Met.
59. A method of treating diseases or disorders associated with uncontrolled, abnormal, andor unwanted cellular activities, the method comprising administering, to a mammal in need thereof, a therapeutically effective amount of the compound as described in claim 44 or a pharmaceutical composition comprising a compound according to claim 44 and a pharmaceutically acceptable carrier.
60. A method of screening for a modulator of a kinase, said kinase selected from c-Met, KDR, c-Kit, fit-3, and flt-4, the method comprising combining the compound according to claim 44 and at least one candidate agent and determining the effect of the candidate agent on the activity of said kinase.
61. A method of inhibiting proliferative activity in a cell, the method comprising administering an effective amount of the compound according to claim 44 to a cell or a plurality of cells.
62. The method of claim 55, wherein the compound is administered in combination with a pharmaceutically acceptable carrier.
63. The method of claim 61, wherein the compound is administered in combination with a pharmaceutically acceptable carrier.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An electric power steering device provided with a torque sensor for detecting a torque using coil windings arranged in an electromagnetic yoke,
the electric power steering device comprising:
at least one coil bobbin which is housed in the inside of the electromagnetic yoke;
a terminal block which projects a portion of the coil bobbin outwardly;
connection pins which are formed on the terminal block in a projected manner; and
connection members which connect the connection pins to a sensor circuit substrate,
wherein the connection pins are arranged not to be covered and concealed with the sensor circuit substrate.
2. An electric power steering device according to claim 1, wherein the sensor circuit substrate is arranged with an angle not parallel to an axis of the coil bobbin.
3. An electric power steering device according to claim 1 or 2, wherein the connection members are formed by integrally forming conductive plates which connect the connection pins and the sensor circuit substrate with resin.
4. An electric power steering device according to claim 1 or 2, wherein the connection members are formed by projecting a portion of the sensor circuit substrate in an arm shape.