1. An endovascular method of treating a patient suffering from Alzheimer’s disease comprising the steps of:
conducting preoperative examination of the patient for detecting changes that occurred in the patient’s brain in connection with Alzheimer’s disease and for defining angioarchitechtonica of the arteries and capillaries in the affected zone of the brain;
providing a microcatheter device comprising at least a first channel and a second channel, a plurality of microcatheters of gradually reducing diameters for coaxial insertion one into another through the first channel, a light-guiding optical-fiber device connected to a low-power laser source and insertable into the innermost of said at least three microcatheters, and a source of a cleaning liquid for the supply into the area being treated through the second channel;
puncturing and catheterizing the common femoral artery of the patient for installing an introducer;
inserting a first microcatheter of said plurality into the introducer;
coaxially inserting and moving forward the second microcatheter of said plurality into the first microcatheters;
coaxially inserting and moving forward the third microcatheter of said plurality into the second microcatheters;
if necessary, sequentially inserting and moving forward other microcatheters of said plurality into the preceding microcatheter until reaching the affected zone of the microcirculation bloodstream in the patient’s brain; inserting the light-guiding optical-fiber device coaxially into the innermost catheter of said plurality;
guiding the light-guiding optical-fiber device to the affected zone through the innermost catheter; and
restoring the circulation and collateral bloodstream in the brain with regeneration of the surrounding brain tissue by conducting laser treatment of the affected zone through a coronary blood vessel adjacent to the affected zone.
2. The method of claim 1, wherein the aforementioned microcatheters are made from a radio-opaque material and wherein said laser treatment is carried out under X-ray TV observation.
3. The method of claim 2, wherein the aforementioned laser has a power not less than 20 mW, said laser treatment being carried out in a mode selected from a continuous mode, pulsed mode, and a combined continuous-pulsed mode.
4. The method of claim 3, wherein the second microcatheter is coaxially inserted into the first microcatheter, the third microcatheter is inserted into the second microcatheter, and if necessary, other smaller-diameter microcatheters are sequentially inserted one into the other and moved forward to the medial cerebral artery or the anterior cerebral artery.
5. The method of claim 1, wherein said plurality is three to six microcatheters.
6. The method of claim 2, wherein said plurality is three to six microcatheters.
7. The method of claim 4, wherein said plurality is three to six microcatheters.
8. The method of claim 1, wherein the microcatheters of said plurality have distal ends with a shape memorized by shape memory and wherein said shape corresponds to the angioarchitechtonica defined in said step of preoperative examination of the patient.
9. The method of claim 4, wherein the microcatheters of said plurality have distal ends with a shape memorized by shape memory and wherein said shape corresponds to the angioarchitechtonica defined in said step of preoperative examination of the patient.
10. The method of claim 1, wherein the washing liquid is a heparinizated physiological solution.
11. The method of claim 4, wherein the washing liquid is a heparinizated physiological solution.
12. The method of claim 9, wherein the washing liquid is a heparinizated physiological solution.
13. The method of claim 1, wherein after inserting the light-guiding optical-fiber device coaxially into the innermost catheter of said plurality, the first catheter is shifted and positioned in the descending arch of the aorta, and the innermost catheter or several preceding catheters isare shifted and positioned in the proximal part of the common carotid artery of the patient.
14. The method of claim 4, wherein after inserting the light-guiding optical-fiber device coaxially into the innermost catheter of said plurality, the first catheter is shifted and positioned in the descending arch of the aorta, and the innermost catheter or several preceding catheters isare shifted and positioned in the proximal part of the common carotid artery of the patient.
15. The method of claim 9, wherein after inserting the light-guiding optical-fiber device coaxially into the innermost catheter of said plurality, the first catheter is shifted and positioned in the descending arch of the aorta, and the innermost catheter several preceding catheters isare shifted and positioned in the proximal part of the common carotid artery of the patient.
16. The method of claim 12, wherein after inserting the light-guiding optical-fiber device coaxially into the innermost catheter of said plurality, the first catheter is shifted and positioned in the descending arch of the aorta, and the innermost catheter or several preceding catheters isare shifted and positioned in the proximal part of the common carotid artery of the patient.
17. The method of claim 1, wherein the preoperative examination of the patient comprises computerized tomography and magnetic resonance tomography of the brain, scintography, rheography, and brain angiography for revealing involuntary changes accompanied by atrophy of the cerebral cortex in the frontal and parietal parts of the brain, abnormalities in the structure of the hippocampus, abnormalities in the blood circulation, abnormalities in pulse volume in carotid sinuses, as well as reduction in the capillary phase of contrast enhancement in the frontoparietal areas with development of multiple arteriovenous shunts.
18. A method of treating a patient suffering from Alzheimer’s disease comprising the steps of:
locating areas of the brain of said patient that are affected by Alzheimer’s disease; and
acting on the aforementioned areas of the brain of said patient that are affected by Alzheimer’s disease by means of laser through coronary blood vessels located adjacent to the aforementioned areas and delivered to said area through a set of microcatheters insertable sequentially and coaxially into each other.
19. The method of claim 18, wherein the set of microcatheters consists of three to six microcatheters having diameters from 9 F (3 mm) to 3 F
20. The method of claim 19, wherein the aforementioned step of acting by means of laser is carried out with the use of an optical-fiber light-guide having a diameter of 2 F and insertable into the innermost catheter of said set.
21. A device for endovascular treatment of a patient suffering from Alzheimer’s disease by means of laser treatment of the affected zone of the patient’s brain comprising a:
microcatheter device having a proximal end and a distal end;
connection unit at the proximal end with at least a first channel and a second channel;
set of microcatheters of gradually reduced diameters insertable through the first channel coaxially and sequentially one into the other and having the innermost microcatheters of said set with diameters insertable into distal coronary blood vessels of the aforementioned affected zone;
source of a washing liquid for delivering a washing liquid to the area of laser treatment through the second channel; and
an optical-fiber light-guide insertable into the innermost catheter of said set and connected to a laser source.
22. The device of claim 21, wherein the microcatheters of said set are made from a radio-opaque material detectable by X-ray TV observation, have proximal ends and distal ends, and where the distal ends of the innermost microcatheters of the set have a shape memorized by shape memory.
23. The device of, wherein the laser source is a low-power laser source.
24. The device of claim 23, wherein the washing liquid is a heparinizated physiological solution.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An absorbent product comprising:
(i) a package comprising a first panel and a second panel opposed to the first panel, the package comprising a first window area in the first panel, a second window area in the second panel, and an ultraviolet barrier area at least partially disposed in the second panel, the ultraviolet barrier area comprising an ultraviolet absorbing agent; and
(ii) a plurality of absorbent articles which are stacked and contained in the package;
each of the absorbent articles having a body facing surface and an external surface opposed to the body facing surface; each of the absorbent articles having a front region and a rear region opposed to the front region; each of the absorbent articles comprising a liquid permeable topsheet, a liquid impermeable backsheet, an absorbent core disposed between the topsheet and the backsheet, and a disposable tape secured to the external surface of the rear region; each of the absorbent articles comprising a graphic in the front region and in the rear region; the front region facing the first panel and the rear region facing the second panel; the graphic of the front region being visible through the first window area and the disposable tape being covered by the ultraviolet barrier area;
wherein the graphic of the front region is more visible than the graphic of the rear region when viewed from outside.
2. The absorbent product of claim 1 wherein a graphic feature of the front region is more perceivable than a graphic feature of the rear region.
3. The absorbent product of claim 2 wherein the graphic feature is a primary element of the graphic or a design element of the graphic.
4. The absorbent product of claim 1 wherein the first window area is larger than the second window area.
5. The absorbent product of claim 1 wherein the first window area allows more light transmittance than the second window area.