1. A substantially enantiomerically pure composition of (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one having the structure:
or a salt or crystal thereof.
2. A method of treating diabetes in a subject in need thereof comprising administering a therapeutically effective amount of a substantially enantiomerically pure composition of (+)-(4S, 5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one potassium salt.
3. A method of treating a condition responsive to PPAR\u03b3 modulation in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a substantially enantiomerically pure composition of (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one potassium salt.
4. The method of claim 2 or 3, wherein the substantially enantiomerically pure composition further comprises a pharmaceutically acceptable carrier.
5. The method of claim 2 or 3 wherein the enantiomerical purity of (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one potassium salt is 98% or higher.
6. The method of claim 5 wherein the enantiomerical purity of (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one potassium salt is 99% or higher.
7. The method of claim 6 wherein the enantiomerical purity of (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one potassium salt is 99.5% or higher.
8. The method of claim 2 or 3, wherein the condition is selected from the group consisting of diabetes and obesity.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A medical information management apparatus communicably connected to a plurality of client terminals, comprising:
a reference information storage device configured to store reference information for medical information referred to by a participant in a past medical meeting;
a recommended information acquisition device configured to acquire recommended medical information from medical information of a target patient in a current medical meeting based on the reference information; and
a providing device configured to provide the acquired recommended medical information to each of the client terminals.
2. The medical information management apparatus of claim 1, wherein the recommended information acquisition device acquires the recommended medical information in accordance with role information of a participant in the current medical meeting.
3. The medical information management apparatus of claim 2, wherein the providing device changes the acquired recommended medical information in accordance with role information of an owner of the client terminal and provides the changed recommended medical information to the client terminal.
4. The medical information management apparatus of claim 1, wherein the recommended information acquisition device acquires a type of the recommended medical information based on reference information for medical information referred to in the same type of medical meeting held in the past, and acquires the recommended medical information in accordance with the acquired type.
5. The medical information management apparatus of claim 1, further comprising a device configured to acquire conversation information in the medical meeting,
wherein the recommended acquisition device acquires the recommended medical information in accordance with the conversation information.
6. The medical information management apparatus of claim 1, wherein the providing device provides medical information about the target patient which is generated in and after a previous medical meeting.
7. The medical information management apparatus of claim 1, wherein the recommended information acquisition device acquires medical information about the target patient from another apparatus via a network.
8. The medical information management apparatus of claim 1, further comprising a medical information storage device configured to acquire medical information about the target patient from another apparatus via a network and storing the information.
9. The medical information management apparatus of claim 1, wherein the reference information storage device stores reference information for medical information referred to by the plurality of client terminals during the medical meeting.
10. The medical information management apparatus of claim 1, wherein the reference information contains identification information of the referred medical information and is stored in the reference information storage device in association with identification information of the medical meeting and identification information of a participant in the medical meeting.