What is claimed is:
1. The following DNA (a) or (b):
(a) a DNA comprising the nucleotide sequence represented by SEQ ID NO:1, or
(b) a DNA hybridizable with the DNA of SEQ ID NO:1 under stringent conditions and encoding a cellular adhesion molecule.
2. A protein encoded by the DNA as defined in claim 1.
3. The following protein (a) or (b):
(a) a protein comprising the amino-acid sequence represented by SEQ ID NO:2, or
(b) a cellular adhesion molecule comprising an amino acid sequence wherein deletion, substitution or addition of one or more amino acids has occurred in the amino acid sequence of SEQ ID NO:2.
4. The following DNA (a) or (b):
(a) a DNA comprising the nucleotide sequence represented by SEQ ID NO:4, or
(b) a DNA hybridizable with the DNA of SEQ ID NO:4 under stringent conditions and encoding a protein having at least one activity selected from an activity of binding to a sialic acid-containing sugar chain, an activity of proliferating lymphocytes and an activity of enhancing the production of IL-2.
5. A protein encoded by the DNA as defined in claim 4.
6. The following protein (a) or (b):
(a) a protein comprising the amino acid sequence represented by SEQ ID NO:5, or
(b) a protein comprising an amino acid sequence wherein deletion, substitution or addition of one or more amino acids has occurred in the amino acid sequence of SEQ ID NO:5 and having at least one activity selected from an activity of binding to a sialic acid-containing sugar chain, an activity of proliferating lymphocytes and an activity of enhancing the production of IL-2.
7. A fused protein comprising the protein as defined in claim 6.
8. A recombinant vector including the DNA as defined in claim 1.
9. A transformant produced by transformation with the recombinant vector as defined in claim 8.
10. An antisense nucleic acid inhibiting the expression of the protein as defined in claim 2 or 3.
11. An antisense nucleic acid as defined in claim 10 whose nucleotide sequence is a complementary sequence to the entire or a part of the DNA as defined in claim 1.
12. An antibody against the protein as defined in claim 2 or 3 or its partial peptide.
13. A method of screening an agent capable of controling an activity of the protein as defined in claim 2 or 3, which comprises contacting the protein or the transformant expressing the protein with test substances.
14. A method of screening an agent capable of controling the expression of the DNA as defined in claim 1, which comprises contacting the recombinant vector as defined in claim 8 or the transformant as defined in claim 9 with test substances.
15. A recombinant non-human animal of hrc12337 gene.
16. An assay method for the protein as defined in claim 2 or 3 in a test sample, which comprises using the antibody as defined in claim 12.
17. An assay reagent or kit for the protein as define in claim 2 or 3 in a test sample, which comprises containing the antibody as defined in claim 12.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A button for an operator for an air flow control device, comprising:
a hub portion for mounting on a plunger of the operator; and
an engagement portion for manual engagement to apply force in a direction along the length of the plunger;
the engagement portion of the button having a non-circular label area that is adapted to receive a non-circular label for the operator, with the non-circular label area being configured to present a diamond shape to a viewer of the button in a first mounted orientation on the plunger, and an octagon shape to the viewer in a second mounted orientation on the plunger, with the second mounted orientation being approximately 45 degrees from the first mounted orientation.
2. A button as set forth in claim 1 having a detent portion for enabling indexing of the button on the plunger.
3. A button as set forth in claim 2 wherein the button is indexable at forty-five degree increments on the plunger.
4. A button as set forth in claim 1 wherein the engagement portion of the button has a circular outer periphery with the non-circular recess formed as an ovalized square.
5. A button as set forth in claim 4 wherein the ovalized square recess has opposite flat sides and four rounded corners that form arcs of a single circle.
6. A button as set forth in claim 5 wherein the non-circular recess has a width between opposite flat sides of about 1.3 to 1.5 inches, and wherein the four rounded corners form arcs of a single circle having a diameter of about 1.1 to 1.2 inches.
7. A button as set forth in claim 6 wherein the non-circular recess has a width between opposite flat sides of about 1.395 inches and wherein the four rounded corners form arcs of a single circle having a diameter of about 1.155 inches.
8. A button as set forth in claim 1 wherein the button includes a non-threaded securing portion for securing the button axially to the plunger, the securing portion being located behind the label area to limit access to the securing portion when a label is received on the label area.
9. A button as set forth in claim 8 having a detent portion for enabling indexing of the button on the plunger at 45\xb0 increments on the plunger.
10. A button as set forth in claim 8 further including a threaded securing portion for securing the button to a second type of plunger.