1. A method of treating colon, lung, breast or prostate cancer in an individual in need thereof comprising administering to said individual
a therapeutically effective amount of a composition comprising an ethyl acetate extract of Ganoderma lucidum in an amount of about 10 to about 50 percent by weight of the composition, an ethyl acetate extract of Salvia miltiorrhiza in an amount of about 10 to about 50 percent by weight of the composition, and an ethyl acetate extract of Scutellaria barbata in an amount of about 10 to about 50 percent by weight of the composition, in combination with a therapeutically effective amount of at least one antimetabolite chemotherapeutic agent.
2. The method of claim 1, wherein the composition displays at least one property selected from the group consisting of: anti-inflammatory activity, immunoboosting activity, inducing lymphocytes to release TNF-alpha and inhibiting cell proliferation.
3. The method of claim 2, wherein the anti-inflammatory activity selectively inhibits COX-2 over COX-1.
4. The method of claim 1, further comprising administering to the individual a therapeutically effective amount of one or more additional anticancer treatments selected from the group consisting of radiation therapy, chemotherapy, surgery, immunotherapy, photodynamic therapy, and combinations thereof.
5. The method of claim 1, wherein the cancer is lung cancer selected from the group consisting of small cell lung cancer and non-small cell lung cancer.
6. The method of claim 1, wherein the chemotherapeutic agent is selected from the group consisting of gemcitabine and methotrexate.
7. The method of claim 1, wherein the composition further comprises an organic extract of Camellia sinensis (green tea).
8. The method of claim 1, wherein the composition further includes a pharmaceutically acceptable carrier.
9. A method of treating colon, lung, breast or prostate cancer in an individual in need thereof comprising administering to said individual:
(a) a therapeutically effective amount of a composition consisting of an ethyl acetate extract of Ganoderma lucidum, an ethyl acetate extract of Salvia miltiorrhiza, and an ethyl acetate extract of Scutellaria barbata; and
(b) a therapeutically effective amount of at least one antimetabolite chemotherapeutic agent.
10. The method of claim 9, wherein the composition displays at least one property selected from the group consisting of: anti-inflammatory activity, immunoboosting activity, inducing lymphocytes to release TNF-alpha and inhibiting cell proliferation.
11. The method of claim 10, wherein the anti-inflammatory activity selectively inhibits COX-2 over COX-1.
12. The method of claim 9, wherein the cancer is lung cancer selected from the group consisting of small cell lung cancer and non-small cell lung cancer.
13. The method of claim 9, wherein the chemotherapeutic agent is selected from the group consisting of gemcitabine and methotrexate.
14. The method of claim 9, wherein the cancer is colon cancer.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
What is claimed is:
1. A linear motion guiding apparatus comprising:
a guide member provided with a rolling member running track, and
a movable member arranged so as to be movable along the guide member through a large number of rolling members, said movable member being provided with (i) a rolling member running counter-track corresponding to the rolling member running track of said guide member, (ii) a rolling member returning passage arranged away from said rolling member running counter-track by a prescribed distance and in parallel therewith and (iii) a pair of direction changing passages for connecting the rolling member running counter-track and the rolling member returning passage to permit circulation of the rolling members,
characterized in that:
a resin-formed body for forming a rolling member circulation passage comprises a pair of rolling member passage forming portions extending along both longitudinal sides of said rolling member running counter-track, a returning passage forming portion for forming the rolling member returning passage and a pair of direction changing passage-inner guide forming portions for forming inner peripheral guide portions of said direction changing passages, said resin-formed body being separately formed from a body of said movable member; and
at least two portions of (a) said pair of rolling member passage forming portions, (b) said returning passage forming portion, (c) one of said pair of direction changing passage-inner guide forming portions and (d) another of said pair of direction changing passage-inner guide forming portions are connected with each other through integral forming so that said resin-formed body can be built in the body of said movable member.
2. An apparatus as claimed in claim 1, wherein:
said resin-formed body comprises (i) an integral body of said pair of rolling member passage forming portions and said pair of direction changing passage-inner guide forming portions, and (ii) said returning passage forming portion separately formed from said integral body.
3. An apparatus as claimed in claim 1, wherein:
said resin-formed body comprises (i) an integral body of said pair of rolling member passage forming portions, said returning passage forming portion and one of said pair of direction changing passage-inner guide forming portions, and (ii) another of said pair of direction changing passage-inner guide forming portions separately formed from said integral body.
4. An apparatus as claimed in claim 1, wherein:
said resin-formed body is manufactured by preparing an integral body of said pair of rolling member passage forming portions, said returning passage forming portion and said pair of direction changing passage-inner guide forming portions, and then dividing said pair of rolling member passage forming portions and said returning passage forming portion in longitudinal intermediate portions thereof into respective two parts.
5. An apparatus as claimed in claim 1, wherein
a rolling member retainer is provided, said rolling member retainer being able to retain the rolling members in a train with a prescribed distance kept between adjacent two of the rolling members, and said rolling member retainer having side edge portions projecting from both sides of each of the rolling members; and
guide grooves for guiding the side edge portions of the rolling member retainer are formed on an entire periphery of the rolling member circulation passage.
6. An apparatus as claimed in claim 1, wherein:
each of said direction changing passage-inner guide forming portions has a thin sheet portion, which is to be brought into contact with an end face of the body of said movable member, and said each of said direction changing passage-inner guide forming portions is connected to the rolling member passage forming portions or the returning passage forming portion by means of said thin sheet portion.
7. An apparatus as claimed in claim 1, wherein:
said guide member comprises a guide rail;
said movable member comprises a movable block, which is provided with a horizontal portion, which faces an upper surface of said guide rail and a pair of wing portions, between which the guide rail is held at right and left-hand side surfaces thereof; and
two trains of the rolling members are arranged in a gap between the upper surface of the guide rail and a lower surface of the movable block, and a single train of the rolling members is arranged in each of gaps between the right and left-hand side surfaces of the guide rail and both of the wing portions, so as to provide a total number of trains of four.
8. An apparatus as claimed in claim 1, wherein:
said guide member comprises a guide rail;
said movable member comprises a movable block, which is provided with a pair of wing portions, between which the guide rail is held at right and left-hand side surfaces thereof; and
two trains of the rolling members are arranged in each of gaps between the right and left-hand side surfaces of the guide rail and both of the wing portions, so as to provide a total number of trains of four.
9. An apparatus as claimed in claim 8, wherein:
four direction changing passage-inner guide forming portions are formed corresponding to the four trains of the rolling members, respectively, and said four direction changing passage-inner guide forming portions are integrally connected with each other.
10. An apparatus as claimed in claim 8 wherein:
two direction changing passage-inner guide forming portions located at a side of the right-hand side surface of the guide rail are integrally connected with each other, and other two direction changing passage-inner guide forming portions located at a side of the left-hand side surface of the guide rail are integrally connected with each other.
11. An apparatus as claimed in claim 1, wherein:
said guide member comprises a guide rail;
said movable member is provided with a horizontal portion, which faces an upper surface of said guide rail and a single wing portion, which faces one side surface of the guide rail; and
a single train of the rolling members is arranged in a gap between said one side surface of the guide rail and said single wing portion, and another single train of the rolling members is arranged in a gap between the upper surface of the guide rail and a lower surface of said horizontal portion in a vicinity of a corner of the guide rail.
12. An apparatus as claimed in claim 1, wherein:
said guide member comprises a guide rail;
said movable member comprises a movable block, which is provided with a pair of wing portions, between which the guide rail is held at right and left-hand side surfaces thereof; and
a single train of the rolling members is arranged in each of gaps between the right and left-hand side surfaces of the guide rail and both of the wing portions, so as to provide a total number of trains of two.
13. An apparatus as claimed in claim 1, wherein:
said guide member comprises a guide rail;
said movable member comprises a movable block arranged along one side surface of the guide rail; and
two trains of the rolling members are arranged in a gap between said one side surface of the guide rail and the movable block.
14. An apparatus as claimed in claim 1, wherein:
said guide member comprises a spline shaft; and
said movable member comprises an outer tube, said outer tube is movably supported on said spline shaft through a plurality of trains of the rolling members.