1. A method of detecting magnetic resonance (MR) signals, comprising:
exciting a first set of two or more chemicals into a first set of multiple-quantum (MQ) states of two or more MQ-coherence transfer pathways of the corresponding chemicals;
applying a plurality of multiple-quantum coherence (MQC) selection gradient pulses, wherein the plurality of MQC selection gradient pulses suppress signals from a set of chemicals to be filtered out;
acquiring signals from the first set of two or more chemicals during a first acquisition period;
exciting a second set of chemicals into one or more spin echo pathways; and
acquiring signals from the second set of chemicals during the first acquisition period.
2. The method of claim 1, further comprising:
applying one or more selective pulses at one or more resonant frequencies of the second set of chemicals;
applying a pair of crusher gradients to reduce other signals; and
acquiring a second spin echo signal from the second set of chemicals during a second acquisition period.
3. The method of claim 1, wherein the second set of chemical comprises choline.
4. The method of claim 1, wherein the first set of chemicals comprises one or more of a polyunsaturated fatty acid, lactate, or an antineoplastic agents.
5. The method of claim 1, wherein the set of chemicals to be filtered out comprises one or more of water or a lipid, or other chemicals.
6. The method of claim 1, further comprising applying a fast magnetic resonance spectroscopic imaging (MRSI) technique to scan a k-space.
7. The method of claim 1, wherein the first set of molecules comprises one or more known molecules, and wherein exciting the first set of molecules comprises applying one or more RF pulses based at least in part on one or more scalar coupling constants associated with the one or more known molecules.
8. The method of claim 7, further comprising:
analyzing a spin coupling network of the one or more known molecules to determine one or more resonance frequencies of the one or more known molecules and one or more scalar coupling constants associated with the one or more known molecules; and
determining one or more frequency offsets of the one or more RF pulses based at least in part on the one or more scalar coupling constants associated with the one or more known molecules.
9. A magnetic resonance spectroscopic imaging (MRSI) system, comprising:
a sample that comprises a first set of two or more chemicals, a set of chemicals to be filtered out and a second set of chemicals;
a magnet that applies a B0 field to the first set of chemicals and the set of chemicals to be filtered out;
an excitationdetection component that excites the first set of at least two chemicals into a first set of multiple-quantum (MQ) states into different chemical-specific MQ coherence transfer pathways of two or more chemicals, wherein the excitationdetection component applies a plurality of multiple-quantum coherence (MQC) selection gradient pulses, wherein the plurality of MQC selection gradient pulses suppress signals from a set of chemicals to be filtered out, refocuses the signals of two or more chemicals, and wherein the excitationdetection component acquires signals from the first set of at least two chemicals during a first acquisition period and wherein the excitationdetection component excites the second set of chemicals into one or more spin echo pathways, and wherein the excitationdetection component acquires signals from the second set of chemicals during the first acquisition period.
10. The system of claim 9, wherein the excitationdetection component applies one or more selective pulses at one or more resonant frequencies of the second set of chemicals, applies a pair of crusher gradients to reduce other signals, and acquires a second spin echo signal from the second set of chemicals during a second acquisition period.
11. The system of claim 9, wherein the second set of chemical comprises choline.
12. The system of claim 9, wherein the first set of chemicals comprises one or more of a polyunsaturated fatty acid, lactate, or an antineoplastic agents.
13. The system of claim 9, wherein the set of chemicals to be filtered out comprises one or more of water or a lipid, or other chemicals.
14. The system of claim 9, wherein the excitationdetection component applies a fast magnetic resonance spectroscopic imaging (MRSI) technique to scan a k-space.
15. The system of claim 9, wherein the first set of molecules comprises one or more known molecules, and wherein the excitationdetection component applies one or more RF pulses based at least in part on one or more scalar coupling constants associated with the one or more known molecules.
16. The system of claim 9, further comprising:
a processor that analyzes a spin coupling network of the one or more known molecules to determine one or more resonance frequencies of the one or more known molecules and one or more scalar coupling constants associated with the one or more known molecules, wherein the one or more frequency offsets of the one or more RF pulses are determined based at least in part on the one or more scalar coupling constants associated with the one or more known molecules.
17. A magnetic resonance spectroscopic imaging (MRSI) system, comprising:
means for producing a B0 field that acts on a sample that contains a first set of molecules;
means for exciting a first set of chemicals into a first set of multiple-quantum (MQ) states using separate MQ-coherence transfer pathways for different chemicals, wherein the means for exciting further applies a plurality of multiple-quantum coherence (MQC) selection gradient pulses, wherein the plurality of MQC selection gradient pulses suppress signals from a set of chemicals to be filtered out and wherein the means for exciting further excites a second set of chemicals into one or more spin echo pathways; and
means for acquiring signals from the first set of two or more chemicals during a first acquisition period and wherein the means for acquiring further acquires signals from the second set of chemicals during the first acquisition period.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A hearing apparatus, for a user having a hearing canal, comprising:
a microphone connected to signal processing electronics and a power supply;
a housing shaped for use in at least a portion of the hearing canal and including at least one opening;
a microphone hood detachably connected to the housing near the at least one opening, wherein the microphone hood covers the at least one opening and includes at least two external ports that redirect air flow laterally from the axis of the at least one opening; and,
wherein the two external ports communicate with one another to allow passage of a cleaning element through both external ports.
2. The apparatus of claim 1, further comprising a microphone housing connecting the microphone hood to the housing.
3. The apparatus of claim 2, wherein the microphone, the microphone housing and microphone hood are connected, such that air may flow between the at least two external ports and the microphone.
4. The apparatus of claim 3, further comprising a receiver assembly enclosed in the housing.
5. The apparatus of claim 4, wherein the receiver assembly includes a tube and a receiver box coupled to the tube.
6. The apparatus of claim 4, wherein the housing includes a receiver opening and an end of the tube is attached about the receiver opening.
7. The apparatus of claim 4, wherein the housing includes a receiver opening and an end of the tube is attached about the receiver opening using glue.
8. The apparatus of claim 4, wherein the housing is comprised of sections.
9. The apparatus of claim 1, wherein the at least two external ports are linked with a passageway which allows passage of a cleaning element through the at least two external ports.
10. The apparatus of claim 1, further comprising an o-ring adapted to provide a seal between the microphone hood and the housing.
11. The apparatus of claim 1, further comprising a receiver assembly enclosed in the housing.
12. The apparatus of claim 11, wherein the receiver assembly includes a tube and a receiver box coupled to the tube.
13. The apparatus of claim 12, wherein the housing includes a receiver opening and an end of the tube is attached about the receiver opening.
14. The apparatus of claim 12, wherein the housing includes a receiver opening and an end of the tube is attached about the receiver opening using glue.
15. The apparatus of claim 11, wherein the housing is comprised of sections.
16. A hearing apparatus, for a user having a hearing canal, comprising:
a housing adapted to fit within at least a portion of the hearing canal, the housing having at least one access port;
a cover adapted for at least partially covering the at least one access port;
signal processing electronics connected to a microphone, the signal processing electronics adapted to fit within the at least one access port;
a microphone housing, adapted to mount to the housing and the access port, the microphone housing connected to the microphone;
a fastener as a unitary connector of the cover and microphone housing to the housing; and
a microphone hood detachably connected to the microphone housing.
17. The apparatus of claim 16, wherein the microphone hood includes one or more external ports linked to an internal port such that air may flow between the one or more external ports and the internal port.
18. The apparatus of claim 16, wherein the microphone hood includes at least two external ports and the external ports are linked with a passageway which allows passage of a cleaning element through the external ports.
19. The apparatus of claim 16, further comprising an o-ring adapted to provide a seal between the microphone hood and the housing.
20. The apparatus of claim 16, wherein the microphone housing includes battery terminals and the cover is adapted to hold a battery, and the cover is further adapted to move the battery into and out of electrical communication with battery terminals.