1. An apparatus for dividing an entering gas flow (11) into two split flows (20,21) each of which flow through one branch (8,9) of a line system, comprising
a control element (7) in the line system which executes a control motion (26) about a shaft (10) between a first position (27) and a second position (28) to continuously divide the entering gas flow (1) between the split flows (20,21),
the control element (7) being adjustable to divide the gas flow (1) at a volumetric flow ratio VGas,
means supplying a metered input of a medium (5) to the line system at an infeed point (3,25)
the infeed point (3,25) being associated with the control element (7) whereby the control element (7) simultaneously allocates the medium (5) to the split flows (20,21) at different ratio VDos.
2. The apparatus of claim 1 wherein the volumetric flow ratio VGas of the outflowing split flows (20, 21) is variable between a first position (27) and a second position (28) by means of a suitable intermediate position of the control element (7).
3. The apparatus of claim 1 wherein the infeed point (3, 25) of the medium (5) to be metered is received in the bottom region or in the top region of the flow cross section (2, 29).
4. The apparatus of claim 1 wherein the infeed point (3, 25) protrudes in fingerlike fashion into the free flow cross section (2, 29).
5. The apparatus of claim 1 wherein the control element (7) includes vanelike face portions (22.1, 22.2) that are embodied symmetrically to the shaft (10).
6. The apparatus of claim 5 wherein the vanelike face portions (22.1, 22.2) each include window-like openings (24.1, 24.2).
7. The apparatus of claim 5 wherein the vanelike face portions (22.1, 22.2), in the first position (27) or the second position (28), are positioned at bearing edges (23.1, 23.2, 23.3) of the flow cross section (2).
8. The apparatus of claim 1 wherein the control element (7) is embodied as a flap element pivotably connected on one end, whose flap face (35) is received on a wall of the flow cross section (29).
9. The apparatus of claim 8 further comprising tubular portions (31, 32), which are offset from one another in the flap face (35), the tubular portions (31,32) being received on both sides of the flap face (35).
10. The apparatus of claim 9 further comprising funnel-shaped inlets (30) associated with the tubular portions (31, 32), on the ends opposite the flap face (35).
11. The apparatus of claim 8 further comprising the tubular portions (31, 32) are received at an angle to one another on the flap face (35).
12. The apparatus of claim 9 wherein the infeed point (3, 25) of the medium(5) to be metered is located upstream and in front of the tubular portion (31) of the control element (7), which tubular portion is associated with the flow cross section (2) of the entering gas flow (1).
13. The apparatus of claim 1 wherein the control element (7) is embodied on a hollow shaft (40), and wherein interior the infeed point (3, 25) for the medium (5) to be metered is received in the interior of the hollow shaft.
14. The apparatus of claim 13 wherein the wall of the hollow shaft (40) is pierced by window-like openings (24.1, 24.2), and wherein face portions (22.1, 22.2) are received on the hollow shaft (40).
15. The apparatus of claim 5 wherein the face portions (22.1, 22.2) are received at an angled disposition to one another.
16. The apparatus of claim 14 wherein the face portions (22.1, 22.2) are received at an angled disposition to one another.
17. The apparatus of claim 1 wherein the control element (7) comprises a drive unit (51) and wherein, upon failure of the drive unit (51), the control element 7 automatically moves into a middle position between the first position and second position (27, 28), so that the branches (8, 9) downstream of the control element (7) are subjected uniformly to the entering gas flow (1).
18. The apparatus of claim 1 wherein the control element (7) is embodied as disk-segment-shaped and is rotatable in the free flow cross section (2) about a pivot shaft (63) which is located parallel to the flow.
19. The apparatus of claim 18 wherein the disklike control element (7) includes edge portions (76, 77), extending parallel to one another, which define mean cross sections for split flows of the entering gas flow (1).
20. The apparatus of claim 19 wherein the edges (76, 77) opposite one another on the disk-segment-shaped control element (7) are of different edge lengths.
21. The apparatus of claim 1 wherein the control element (7) has openings or partial perforations, configured as oblong slots, in its surface.
22. The apparatus of claim 18 further comprising groovelike metering agent conduits (72, 79) embodied on the outer circumference of the disk-segment-shaped control element (7).
23. The apparatus of claim 22 wherein the disk-segment-shaped control element (7) in the flow cross section (2) is guided in a groove (83), which is embodied on the boundary wall of the flow cross section (2).
24. The apparatus of claim 22 wherein the metering agent conduits (72, 79) of the control element (7) are joined in disk form with a metering conduit portion (73) embodied in the boundary wall of the flow cross section (2).
25. The apparatus of claim 24 wherein the means supplying the metered input of a medium comprises a metering device (4) containing a tube evaporator (65, 69) is associated with the control element (7).
26. The apparatus of claim 17 wherein the control element (7) is embodied as disc-segment-shaped and is rotatable in the free flow cross section (2) about a pivot shaft (63) which is located parallel to the flow, and wherein, the apparatus further comprising drive means actuating the disk-segment-shaped control element (7), the drive means being coupled to the pivot shaft (63) of the control element (7) via a drive shaft (62).
27. The apparatus of claim 26 wherein the control element (7) in disk-segment form is rotatable in a first direction of rotation (61) by means of an electric drive (51) or a pneumatic drive.
28. The apparatus of claim 26 wherein the control element (7) in disk-segment form is rotatable in a second direction of rotation (64) by means of an electric drive (51) or a pneumatic drive.
29. The apparatus of claim 5 wherein the control element (7) is in flap form and is actuatable by means of an electric drive (51) in both a first direction of rotation (61) and the second direction of rotation (64).
30. The use of the apparatus of claim 1 in an assembly for exhaust gas posttreatment of internal combustion engines, in whose branches (8, 9), regeneratable catalytic converters or storage catalytic converters (15, 16) are received.
31. The use of the apparatus of claim 1 in an assembly for exhaust gas posttreatment of internal combustion engines, in whose branches (8, 9), a particle filter with an upstream oxidation catalytic converter is received.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An interfering peptide having peptide sequence S, of 7 to 12 amino acids, originating from the peptide sequence of an antigenic protein of a microorganism M, said sequence S being aligned with respect to a peptide sequence S\u2032, of 7 to 12 amino acids, originating from the peptide sequence of a target protein of a microorganism M\u2032 different than the microorganism M, it being understood that said sequences S and S\u2032 exhibit at least 50% identity over their length of 7 to 12 amino acids and at least 4 identical or analogous contiguous amino acids, that their length is identical or that they exhibit a difference of 1 or 2 amino acids distributed at one andor the other end of said sequences, and that the peptide V7E having sequence SEQ ID No 2 is excluded.
2. The interfering peptide as claimed in claim 1, wherein the sequences S and S\u2032 have from 8 to 10 amino acids.
3. The interfering peptide as claimed in claim 1, wherein the microorganism M\u2032 is a virus or a bacterium.
4. The interfering peptide as claimed in claim 1, wherein the microorganism M\u2032 is a virus and the microorganism M is a bacterium.
5. The interfering peptide as claimed in claim 1, wherein the microorganism M\u2032 is a bacterium and the microorganism M is a virus.
6. The interfering peptide as claimed in claim 3, wherein the virus is the hepatitis C virus (HCV).
7. The interfering peptide as claimed in claim 6, wherein the microorganism different than the HCV virus is chosen from Staphylococcus aureus, Streptococcus pneumoniae, Bacillus subtilis, Pseudomonas entomophila and Pseudomonas putida (GB-1 strain).
8. The interfering peptide as claimed in claim 1, wherein the peptides having sequence S are chosen from Y7E-1 having sequence SEQ ID No 1, A8E having sequence SEQ ID No 3, Y7E-2 having sequence SEQ ID No 5, D8E having sequence SEQ ID No 6 and E8E having sequence SEQ ID No 4.
9. The interfering peptide as claimed in claim 3, wherein the virus is the human immunodeficiency virus HIV-1.
10. The interfering peptide as claimed in claim 9, wherein the microorganism different than the virus to be detected is Mycoplasma pneumoniae.
11. The interfering peptide as claimed in claim 10, wherein the peptides having sequence S are chosen from E8L-1 having sequence SEQ ID No 7 and E8L-2 having sequence SEQ ID No 8.
12. A method for the in vitro immunoassay-based detection of the presence of a microorganism M in a biological sample comprising or consisting of the detection of at least one antibody AbM directed against a target protein of the microorganism M to be detected, said method comprising or consisting of the steps of:
a) providing at least one interfering peptide having peptide sequence S as defined in claim 1,
b) providing at least one binding partner for said at least one antibody AbM to be detected, required for the immunoassay, said at least one binding partner being derived from said target protein against which the antibody is directed or being the target protein itself, and including the peptide sequence S,
c) carrying out the immunoassay in the presence of said at least one interfering peptide having peptide sequence S, and
d) detecting the presence of the microorganism M by measuring the complex formed between the antibody AbM and the binding partner(s).
13. A method for the in vitro immunoassay-based detection of the presence of a microorganism M\u2032 in a biological sample comprising or consisting of the detection of at least one antibody AbM\u2032 directed against a target protein of the microorganism M\u2032 to be detected, said method comprising or consisting of the steps of:
a) providing at least one interfering peptide having peptide sequence S as defined in claim 1,
b) providing at least one binding partner for said at least one antibody AbM\u2032 to be detected, required for the immunoassay, said at least one binding partner being derived from said target protein against which the antibody is directed or being the target protein itself, and including the peptide sequence S\u2032 as previously defined,
c) carrying out the immunoassay in the presence of said at least one interfering peptide having peptide sequence S, and
d) detecting the presence of the microorganism by measuring the complex formed between the antibody AbM\u2032 and the binding partner(s).
14. A method for the in vitro immunoassay-based detection of the presence of a microorganism M in a biological sample comprising or consisting of the detection of at least one target protein of the microorganism M to be detected, said method comprising or consisting of the steps of:
providing at least one binding partner for said at least one target protein of said microorganism M, required for the immunoassay,
providing at least one interfering peptide having sequence S as defined in claim 1, said sequence S being included in the peptide sequence of said at least one target protein,
carrying out the immunoassay in the presence of said at least one interfering peptide having sequence S, and
detecting the presence of the microorganism M by measuring the complex formed between the target protein and the binding partner(s).
15. A method for the in vitro immunoassay-based detection of the presence of a microorganism M\u2032 in a biological sample comprising or consisting of the detection of at least one target protein of the microorganism M\u2032 to be detected, said method comprising or consisting of the steps of:
providing at least one binding partner for said at least one target protein of said microorganism M\u2032, required for the immunoassay,
providing at least one interfering peptide having sequence S as defined in claim 1, it being understood that the corresponding sequence S\u2032 is included in the peptide sequence of said at least one target protein,
carrying out the immunoassay in the presence of said at least one interfering peptide having sequence S, and
detecting the presence of the microorganism M\u2032 by measuring the complex formed between the target protein and the binding partner(s).
16. A method for the in vitro immunoassay-based detection of an analyte representative of a microorganism M or M\u2032 to be detected, comprising an interfering peptide having peptide sequence S as defined in claim 1, in a biological sample.
17. A method for improving the specificity of a method for the in vitro immunoassay-based detection of an analyte representative of a microorganism M or M\u2032 to be detected, in a biological sample, comprising at least one peptide having peptide sequence S as defined in claim 1 during the implementation of the immunoassay.
18. The method as claimed in claim 12, in which the microorganism M or M\u2032 to be detected is a virus or a bacterium.
19. The method as claimed in claim 12, wherein the microorganism M or M\u2032 to be detected is a virus and the corresponding microorganism M\u2032 or M is a bacterium.
20. The method as claimed in claim 12, wherein the microorganism M or M\u2032 to be detected is a bacterium and the corresponding microorganism M\u2032 or M is a virus.
21. A peptide Y7E-1 having sequence SEQ ID No 1.
22. A peptide A8E having sequence SEQ ID No 3.
23. A peptide E8E having sequence SEQ ID No 4.
24. A peptide Y7E-2 having sequence SEQ ID No 5.
25. A peptide D8E having sequence SEQ ID No 6.
26. A peptide E8L-1 having sequence SEQ ID No 7.
27. A peptide E8L-2 having sequence SEQ ID No 8.