1. A portable computer, comprising:
a base comprising, between a front end and a rear end, a first area disposed at a front side of the base and a second area disposed at a rear side of the base;
a display module which comprising a connecting end, a display face, and a support plane opposite to the display face; and
at least one supporting element, each supporting element comprising a first fixed end and a second fixed end, the first fixed end being pivotally connected to a portion of the display module other than the display face so that the display module is able to rotate relative to the supporting element; the second fixed end being pivotally connected to the rear end of the base or a proximity of the rear end of the base so that the supporting element is able to rotate relative to the base; and
at least one sliding assembly, each sliding assembly comprising a sliding block and a slide rail, the slide rail being disposed at least in the second area of the base, the sliding block being connected with the connecting end of the display module and sliding along the slide rail, wherein the sliding block comprises at least one auxiliary sliding structure to reduce friction between the sliding block and the slide rail;
whereby, when the display module is opened and rotated to a suitable angle relative to the base via the second fixed end of the support element, the display module further rotates around the first fixed end with the first fixed end serving as a pivot point and simultaneously drives the connecting end to move from the second area towards the first area to a suitable position along with the sliding element; and
then the display module is supported by the support element to keep a suitable tilted angle.
2. The portable computer as claimed in claim 1, wherein the first area is disposed with a keyboard.
3. The portable computer as claimed in claim 1, wherein the supporting element has a length not smaller than a distance between the connecting end of the display module and the first fixed end of the supporting element.
4. The portable computer as claimed in claim 1, wherein the sliding block further comprises a pivoting portion, a sliding portion, and a connecting portion, the sliding portion is connected to the pivoting portion via the connecting portion, and the connecting end of the display module is pivotally connected to the sliding block via the pivoting portion; the sliding portion is disposed within the slide rail and the at least one auxiliary sliding structure is disposed on the sliding portion.
5. The portable computer as claimed in claim 4, wherein the base further comprises a surface having a slit; the slide rail is disposed below the surface, and the connecting portion of the sliding block goes through the slit so that the pivoting portion and a portion of the connecting portion protrude out of the surface; the slit has a width smaller than that of the sliding portion.
6. The portable computer as claimed in claim 5, wherein the pivoting portion and the surface of the base are spaced apart by a spacing.
7. The portable computer as claimed in claim 1, wherein the auxiliary sliding structure is at least one convex-like structure disposed at the outer surface of the sliding portion to reduce the contact area between the sliding portion and the slide rail.
8. The portable computer as claimed in claim 7, wherein the convex-like structure is a convex spot or a convex strip.
9. The portable computer as claimed in claim 1, wherein the auxiliary sliding structure is at least one groove-like structure disposed at the outer surface of the sliding portion, and each groove-like structure stores a material with the characteristic of lubricity to reduce the friction between the sliding portion and the slide rail.
10. The portable computer as claimed in claim 1, wherein the auxiliary sliding structure is a bush-like structure disposed at the outer surface of the sliding portion, and the bush-like structure is made of a material with the characteristic of lubricity to reduce the friction between the sliding portion and the slide rail.
11. The portable computer as claimed in claim 1, wherein the auxiliary sliding structure is at least a sheet-like structure with a flat surface disposed at the outer surface of the sliding portion to reduce the friction between the sliding portion and the slide rail.
12. The portable computer as claimed in claim 4, wherein the sliding assembly further comprises at least one positioning element, each positioning element is disposed at a fixed point in the slide rail, and the sliding portion further comprises a positioning portion, a positioning effect can be provided via the interference of each positioning element and the positioning portion as the sliding block slides to the fixed point.
13. The portable computer as claimed in claim 12, wherein the positioning element comprises at least one positioning structure, and the slide rail comprises at least one hole disposed corresponding to the position of the fixed point; the positioning structure of the positioning element can pass through the hole and be protruded in the slide rail, so the sliding portion can be positioned by the interference of the positioning portion of the sliding portion and the positioning structure.
14. The portable computer as claimed in claim 1, wherein when the display module overlaps with the base in a closed state, the connecting end of the display module and the second fixed end of the supporting element remain on the same axis.
15. The portable computer as claimed in claim 1, wherein when the display module overlaps with the base in a closed state, the connecting end of the display module and the second fixed end of the supporting element are respectively on different axes substantially parallel with each other.
16. The portable computer as claimed in claim 4, wherein the connecting portion and the sliding portion are pivotally connected with each other.
17. The portable computer as claimed in claim 4, wherein the connecting portion comprises an extendable structure and a length of the connecting portion can be adjusted via the extendable structure.
18. The portable computer as claimed in claim 5, wherein the surface having the slit corresponds to the second area; and the slide rail is disposed correspondingly below the surface of the second area corresponding to the slit.
19. The portable computer as claimed in claim 5, wherein the surface having the slit comprises the second area and at least part of or all of the first area; and the slide rail is disposed correspondingly below the surface comprising the second area and at least part of or all of the first area.
20. The portable computer as claimed in claim 1, wherein the at least one supporting element comprises two support elements arranged in parallel.
21. The portable computer as claimed in claim 1, wherein the at least one sliding assembly comprises two sliding assemblies parallel to each other and spaced apart, the two slide rails are disposed in parallel at least in the second area, and each sliding block is respectively and pivotally connected to the connecting end of the display module corresponding to each slide rail.
22. The portable computer as claimed in claim 1, wherein the at least one sliding assembly comprises a single sliding assembly disposed at the central position of at least the second area of the base; the slide rail is disposed at the central position of at least the second area of the base, and the sliding block is correspondingly disposed at the central position of the connecting end of the display module.
23. The portable computer as claimed in claim 1, wherein the sliding block is rotatably and pivotally connected with the connecting end of the display module.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound, or a pharmaceutically acceptable salt, ester, or isomer thereof, of Formula (IV):
wherein L, R1, R2, R3, R4, R5, and R6 are selected independently of each other and wherein:
L is \u2014CH2\u2014S\u2014;
R1 is a benzofused heteroaryl-,
wherein said R1 group is unsubstituted or optionally substituted with from 1 to 5 substituents, which may be the same or different, each independently selected from halogen, hydroxy, \u2014CN, oxo, oxide, alkyl, haloalkyl, haloalkoxy-, hydroxyalkyl-, heteroalkyl, cyanoalkyl-, alkoxy, optionally substituted aryl, optionally substituted \u2014O-aryl, optionally substituted \u2014O-alkyl-aryl, optionally substituted heteroaryl, optionally substituted arylalkyl-, optionally substituted arylalkoxy, \u2014N(R7)2, -alkylN(R7)2, \u2014NC(O)R7, \u2014CO2R7, \u2014SO2R7, and \u2014SO2N(R7)2, wherein said optional substituents are present from 1 to 4 times and may be the same or different, each independently selected from alkyl, halogen, haloalkyl, hydroxyl, \u2014CN, and \u2014N(R11)2;
and wherein the benzo portion of each said benzofused R1 group is optionally further fused to another ring selected from heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, and heterocycloalkenyl,
R2 is \u2014OR8;
R3 is selected from hydrogen, hydroxy, and straight or branched alkyl,
R4 is selected from H and halogen;
R5 is selected from H, halogen, and alkyl;
z (the dotted line) represents a single or double bond, with the proviso that when z is a single bond, R6 is H;
R6 is selected from H and halogen;
each R7 is independently selected from hydrogen, alkyl, haloalkyl, aryl, and heteroaryl,
or, when two groups R7 are attached to the same nitrogen atom, two groups R7 are taken together with the nitrogen atom to which they are attached to form a 3- to 7-membered heterocycloalkyl group;
R8 selected from haloalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, \u2014C(O)NHR9, and \u2014C(O)R11;
R9 is selected from alkyl, haloalkyl, aryl, heteroaryl, cycloalkyl, and heterocycloalkyl, each unsubstituted or optionally substituted with from 1 to 4 substituents independently selected from the group consisting of alkyl, halogen, haloalkyl, hydroxy, \u2014N(R7)2, and \u2014CN;
R10 is selected from hydrogen and alkyl; and
R11 is selected from haloalkyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, and heterocycloalkenyl, each unsubstituted or optionally substituted with from 1 to 4 substituents independently selected from the group consisting of alkyl, halogen, haloalkyl, hydroxy, \u2014N(R7)2, and \u2014CN.
2. A compound according to claim 1, or a pharmaceutically acceptable salt, ester, or isomer thereof, selected from:
3. A compound according to claim 2, or a pharmaceutically acceptable salt, ester, or isomer thereof, selected from:
4. A compound or a pharmaceutically acceptable salt, ester, or isomer thereof of structure:
5. A compound or a pharmaceutically acceptable salt, ester, or isomer therof of stucture:
6. A compound or a pharmaceutically acceptable salt, ester, or isomer thereof of structure:
7. A compound or a pharmaceutically acceptable salt, ester, or isomer thereof of structure: