1-17. (canceled)
18: A method of treating colorectal cancer in a human subject in need thereof comprising administering rNAPc2pro to the subject twice-weekly via subcutaneous injection in a dosage range of about 1 to about 10 \u03bcgkg body weight, and subsequently administering FOLFOX to the subject.
19. The method of claim 18, further comprising administering bevacizumab.
20-82. (canceled)
83. A method for treating cancer comprising administering to a subject in need thereof an anti-metastatic agent and an anti-cancer agent.
84. The method of claim 83, wherein the anti-metastatic agent is a NAP protein.
85. The method of claim 83, wherein the cancer is selected from the group consisting of colorectal cancer, melanoma and lung cancer.
86. A method for decreasing or inhibiting tumor metastasis comprising administering to a subject in need thereof an anti-cancer agent and a NAP protein.
87. A method for reducing tumor burden comprising administering to a subject in need thereof an anti-cancer agent and a NAP protein.
88. The method of claim 83, 86 or 87, wherein the anti-cancer agent is selected from the group consisting of a chemotherapeutic agent and a targeted anti-cancer agent.
89. The method of claim 88, wherein the chemotherapeutic agent is FOLFOX or FOLFIRI.
90. The method of claim 88, wherein the targeted anti-cancer agent is bevacizumab.
91. The method of claim 86 or 87, wherein the anti-cancer agent is administered concurrently, prior to, or subsequent to the NAP protein.
92. The method of claim 83, wherein the anti-cancer agent is administered concurrently, prior to, or subsequent to the anti-metastatic agent.
93. The method of claim 84, 86 or 87, wherein the NAP protein is selected from a group consisting of a NAP protein that has a NAP domain of Formula III, rNAPc2, and rNAPc2pro.
94. The method of claim 84, 86 or 87, wherein the NAP protein is administered subcutaneously.
95. The method of claim 83, 86 or 87, wherein the subject is a mammal.
96. The method of claim 95, wherein the mammal is a human.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A container comprising:
a rigid body constructed from a multilayer reinforced wrap including at least one reinforced sheet and one bonding layer; and
a closeable lid.
2. The container of claim 1, further comprising a honeycomb layer as part of the reinforced wrap.
3. The container of claim 1, further comprising carving patterns embedded therein.
4. The container of claim 1, wherein the rigid body comprises a burial casket shell.
5. The container of claim 1, wherein the reinforced sheet comprises a Fiber Reinforced Polymer (FRP) sheet.
6. The container of claim 1, wherein the bonding layer comprises a curable resin layer.
7. The container of claim 1, wherein the rigid body is constructed using a vacuum mold.
8. The container of claim 1, wherein the closeable lid is constructed from the reinforced wrap.
9. The container of claim 1, wherein the closeable lid is constructed as an integral part of the rigid body.
10. A method of constructing a rigid container, the method comprising:
using a forming mold configured to be used to form a rigid body of the rigid container;
wrapping a reinforced wrap, including at least one reinforced sheet and one bonding layer, around the forming mold; and
curing the bonding layer to harden the rigid body.
11. The method of claim 10, further comprising using an air pump to force the reinforced wrap against a surface of the forming mold.
12. The method of claim 10, further comprising using a separate forming mold to form a lid configured to be integrated with the rigid body.
13. The method of claim 10, wherein the forming mold is a vacuum mold.
14. The method of claim 10, wherein the forming mold includes carvings configured to be embedded in the rigid body.
15. The method of claim 10, wherein the forming mold includes handle cavities configured to be embedded in the rigid body.
16. The method of claim 10, wherein the reinforced sheet comprises a Fiber Reinforced Polymer (FRP) sheet.
17. The method of claim 10, wherein the rigid body includes an integral lid.
18. The method of claim 10, wherein the bonding layer comprises a curable resin.
19. The method of claim 10, wherein the curing the bonding layer comprises using heat or Ultra Violet (UV) light to cure the bonding layer.
20. The method of claim 10, wherein the reinforced sheet comprises a honeycomb layer.