1. A composition for the prevention and treatment of diabetic complications, which contains an extract obtained by: crushing and drying anyone selected from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix; extracting the dried herbal material with alcohol or aqueous alcohol solution; filtering the extract; and concentrating the filtrate under reduced pressure.
2. A composition for the prevention and treatment of diabetic complications, which contains a mixture of extracts from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix, the amount of each of the herbal extracts being 5-85% by weight based on 100% by weight of the herbal extract mixture.
3. A composition for the prevention and treatment of diabetic complications, which contains an herbal extract mixture obtained by: crushing and drying each of Euphorbiae Radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix: mixing the crushed herbal materials together, each of the herbal materials being used at an amount of 5-85% by weight based on the total weight of the herbal materials taken as 100% by weight: extracting the herbal mixture with alcohol or aqueous alcohol solution; filtering the extract; and concentrating the filtrate under reduced pressure.
4. A pharmaceutical composition for the prevention or treatment of diabetic complications, which contains, as an active ingredient, an extract obtained as claimed in claim 1.
5. A functional food for the prevention or treatment of diabetic complications, which contains, as an active ingredient, an extract obtained as claimed in claim 1.
6. A pharmaceutical composition for the prevention and delay of aging, which contains, as an active ingredient, an extract obtained as claimed in claim 1.
7. A functional food for the prevention and delay of aging, which contains, as an active ingredient, an extract obtained as claimed in claim 1.
8. A composition for the prevention or treatment of diabetic complications, which contains, as an active ingredient, magnolol isolated from Magnolia bark, or a pharmaceutically acceptable salt thereof.
9. The composition of claim 8, wherein the magnolol is obtained by: extracting Magnolia bark with 80% ethanol aqueous solution at ambient temperature for 24 hours; systematically separating the extract in the order of normal-hexane, ethyl acetate and normal-butanol; selecting the normal-hexane layer 20 and separating the selected layer into pre-fractions by normal silica gel chromatography; comparing the pre-fractions with the standard form magnolol on TLC to determine a magnolol-enriched fraction; and separating magnolol from the magnolol-enriched fraction by silica gel column chromatography.
10. A pharmaceutical composition for the prevention or treatment of diabetic complications, which contains, as an active ingredient, magnolol obtained as claimed in claim 8.
11. A functional food for the prevention or treatment of diabetic complications, which contains, as an active ingredient, magnolol obtained as claimed in claim 8.
12. A pharmaceutical composition for the prevention and 35 delay of aging, which contains, as an active ingredient, magnolol obtained as claimed in claim 8.
13. A functional food for the prevention and delay of aging, which contains, as an active ingredient, magnolol obtained as claimed in claim 8.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. Apparatus for cleaning the interior surface of a containment wall containing a water pool, said apparatus comprising:
a body adapted to be immersed in said water pool;
at least one first discharge outlet on said body oriented to discharge a water flow in a direction acting to move said body in a first direction;
at least one second discharge outlet on said body oriented to discharge a water flow in a direction acting to move said body in a second direction different from said first direction; and
a propulsion subsystem for selectively providing a water flow to said first discharge outlet or said second discharge outlet, said propulsion subsystem comprising:
a valve assembly including an inlet port and first and second outlet ports, said inlet port being adapted to receive a water flow supplied by a positive pressure source, said first outlet port being coupled to said first discharge outlet, and said second outlet port being coupled to said second discharge outlet;
a valve element mounted for reciprocal linear movement between first and second positions such that said valve element in said first position closes said second outlet port and in said second position closes said first outlet port;
a hydraulic actuator for moving said valve element between said first and second positions, said actuator comprising at least one piston having first and second oppositely directed faces; and
means for selectively applying water pressure supplied by said positive pressure source to said faces to selectively move said valve element to said first position or second position.
2. The apparatus of claim 1 wherein said means applying water pressure to said faces includes means continuously applying said water pressure to said second face acting in a direction to restore said valve element to said second position; and
means for selectively applying said water pressure to said first face for moving said valve element to said first position.
3. The apparatus of claim 1 wherein said means for applying water pressure to said first face includes a controller having a first control port and wherein said controller is operable to selectively produce said water pressure at said first control port.
4. The apparatus of claim 1 wherein said piston first face has an area larger than the area of said second face whereby an equal pressure applied to said first and second faces produces a greater force on said first face for moving said valve element to said first position.
5. The apparatus of claim 1 wherein said means applying water pressure to said faces includes a controller selectively operable to apply said pressure to either said first face or said second face.
6. The apparatus of claim 1 wherein said second discharge outlet includes first and second nozzles mounted on said body in spaced relationship and oriented to discharge water flows having spaced horizontal components for producing a moment to rotate said body.
7. The apparatus of claim 6 wherein at least one of said nozzles is oriented to discharge a water flow having a vertical component for lifting said body.