1. An addition to a medical applicator, the medical applicator configured for applying a curable liquid substance, and including a lumen inlet for receiving therein gas from an exterior source, and a tubular body for applying the curable liquid substance on a surface, wherein the tubular body is in fluid communication with the lumen inlet, the addition comprising a turbulating unit configured for mixing said gas with a powder stored in a vial, the turbulating unit having:
an inlet port connectable to the exterior source;
an outlet port connectable to the lumen inlet of the medical applicator; and
a spike member configured for being entered into the vial and having a first passage for providing fluid communication between said inlet port and the vial, and a second passage for providing fluid communication between the vial and said outlet port;
whereby assembling the addition with the medical applicator enables delivery of the substance and the powder on the surface.
2. The addition of claim 1, wherein said delivery of the substance and the powder on the surface is carried out simultaneously.
3. The addition of claim 1, wherein said delivery of the substance and the powder on the surface is carried out sequentially.
4. The addition of claim 1, wherein said delivery of the substance and the powder on the surface is carried out alternatingly.
5. The addition of claim 1, wherein said second passage is configured to allow a flow of the gas homogeneously mixed with the powder.
6. The addition of claim 1, wherein said spike member includes a beveled tip configured for introducing said spike through a membrane covering the opening of the vial.
7. The addition of claim 1, wherein said gas is a medical gas, and wherein said powder is a medicament.
8. The addition of claim 1 to 7, wherein said powder comprises solid fibrinogen particles andor solid thrombin particles.
9. The addition of claim 1, wherein the substance includes at least a first component and a second component, wherein said first component being activated by said second component.
10. The addition of claim 9, wherein the tubular body contains a first channel for transferring therethrough said first component, a second channel for transferring therethrough said second component, and a third channel for transferring therethrough said powder.
11. The addition of claim 9, wherein the applicator comprises a first cannula hub for providing therethrough said first component and a second cannula hub for providing therethrough said second component.
12. The addition of claim 9, wherein said first component comprises liquid fibrinogen, and said second component comprises liquid thrombin.
13. The addition of claim 1, wherein said turbulating unit is configured for sealing engagement with the opening of the vial.
14. The addition of claim 1, wherein said turbulating unit is configured to homogeneously mix said powder with said gas.
15. The addition of claim 1, wherein said turbulating unit is configured to form a mixture of said powder and said gas with a predetermined concentration of said powder in said gas.
16. The addition claim 1, further comprising a first lumen configured for fluidly coupling said inlet port to said exterior source.
17. The addition of claim 16, further comprising a second lumen configured for fluidly coupling said outlet port to said lumen inlet of the medical applicator.
18. The addition of claim 17, further comprising a bypass lumen fluidly coupling said first lumen directly with said second lumen.
19. The addition of claim 18 further comprising a valve coupled to said bypass lumen, said valve being configured to shift between a first position in which fluid flow is allowed between said exterior source and said vial whereby said powder is mixed with said gas, and a second position in which fluid flow is allowed between said exterior source and said bypass lumen whereby said gas flows directly to said lumen inlet.
20. The addition of claim 19, wherein said valve allows gas flow from said exterior source, to be apportioned from said first lumen into said inlet port and into said bypass lumen.
21. An applicator assembly comprising:
at least one cannula hub for providing therethrough a curable liquid substance;
a lumen inlet for receiving therein gas from an exterior source; and
a turbulating unit configured for mixing said gas with a powder stored in a vial, said turbulating unit including
an inlet port connectable to said exterior source;
an outlet port connectable to said lumen inlet; and
a spike member configured for being entered into the vial and having a first passage for providing fluid communication between said inlet port and said vial and a second passage for providing fluid communication between said vial and said outlet port; and
a tubular body for applying said substance and a mixture of said gas and said powder on a surface.
22. The applicator assembly of claim 21 further comprising a first lumen fluidly coupling said inlet port to said exterior source.
23. The applicator assembly of claim 22 further comprising a second lumen fluidly coupling said outlet port to said lumen inlet.
24. The applicator assembly of claim 23 further comprising a bypass lumen fluidly coupling said first lumen directly with said second lumen.
25. The applicator assembly of claim 24 further comprising a valve coupled to said bypass lumen said valve being configured to shift between a first position in which fluid flow is allowed between said exterior source and said vial whereby said powder is mixed with said gas, and a second position in which fluid flow is allowed between said exterior source and said bypass lumen whereby said gas flows directly to said lumen inlet.
26. The applicator assembly of claim 25, wherein said valve allows gas flow from said exterior source, to be apportioned from said first lumen into said inlet port and into said bypass lumen.
27. The applicator assembly of any one of claims 21 to 26, wherein said substance includes a first component and a second component, wherein said first component being activated by said second component, and wherein said assembly includes a first cannula for transferring therethrough said first component, a second cannula for transferring therethrough said second component.
28. The applicator assembly of any one of claims 27 to 28, wherein the tubular body contains a first channel for transferring therethrough said first component, a second channel for transferring therethrough said second component, and a third channel for transferring therethrough said powder.
29. A method for applying a powder and a liquid curable substance on a surface, by utilizing an applicator assembly of any one of claims 21 to 28, the method comprising:
providing pressurized gas into a vial having the powder stored therein, such that a mixture of said gas and said powder is formed;
transferring said mixture towards said lumen inlet;
applying with said tubular body said mixture on the surface;
providing the substance into a cannula hub; and,
applying with said tubular body said substance on the surface.
30. The method of claim 29, wherein said step of applying said substance and said step of applying said mixture are carried out simultaneously.
31. The method of claim 29, wherein said step of applying said substance and said step of applying said mixture are carried out sequentially.
32. The method of claim 29, wherein said step of applying said mixture and said step of applying said substance are carried out alternatingly.
33. The method of claim 29, wherein said substance is formed by a first component and a second component, and wherein said first component is being activated by said second component.
34. The method of claim 29, wherein said surface is a moist surface.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An imaging array comprising:
a CCD imaging array comprising a plurality of pixels that accumulate charge when exposed to light;
a readout amplifier comprising
an operational amplifier having an input and an output port and a feedback capacitor connecting said input and output ports;
a variable impedance path between said input and output ports, said path having an impedance controlled by a reset signal;
a reset signal generator that generates said reset signal, said reset signal having three sequential phases, a first phase in which said path has a first impedance, a second phase in which said path has an impedance greater than a second impedance, and a third phase in which said path has an impedance greater than a cut-off impedance, said second impedance being greater than said first impedance; and
a shift register that sequentially shifts said charge accumulated by each pixel into said input port, said reset signal generator applying said reset signal prior to each charge being shifted into said input port, wherein said readout amplifier generates an output indicative of said charge shifted into said input port during said third phase.
2. The imaging array of claim 1 wherein
said variable impedance path comprises a transistor having a source and drain connected respectively to said input and output ports, and wherein said first phase comprises a signal having an amplitude sufficient to cause said transistor to provide a path having an impedance that is less than ten thousand ohms.
3. The imaging array of claim 2 wherein said second phase comprises a continuously changing potential from said amplitude of said first signal to a potential that causes said transistor to have an impedance greater than said cut-off impedance.
4. The imaging array of claim 1 wherein said feedback capacitor comprises a capacitor array having a first node connected to said input port and a second node connected to said output port, said capacitor array comprising a plurality of capacitors in which each capacitor has a capacitance that is greater than the capacitance between said first and second nodes.
5. The imaging array of claim 1 further comprising a first sample and hold circuit for recording a potential at said output port at the end of said third phase but before said charge is shifted into said input port;
a second sample and hold circuit for recording a potential at said output port after said charge is shifted into said input port;
a subtraction circuit for subtracting said potentials recorded by said first and second sample and hold circuits.
6. A method for reading out a CCD imaging array comprising a plurality of pixels that accumulate charge when exposed to light, said imaging array including a readout amplifier having
an operational amplifier having an input and an output port and a feedback capacitor connecting said input and output ports; and
a variable impedance path between said input and output ports, said path having an impedance controlled by a reset signal, said method comprising:
causing said variable impedance path to provide a first impedance for a first period of time;
causing said variable impedance path to provide a second impedance for a second period of time;
causing said variable impedance path to provide a third impedance for a third period of time;
inputting said charge from one of said pixels into said input port during said third period of time;
measuring a signal at said output port during said third period of time, wherein
said first impedance is less than said second impedance and wherein said third impedance is greater than a cut-off impedance.
7. The method of claim 6 further comprising recording a first potential at said output port at the end of said second period of time;
recording a second potential at said output port after said charge is shifted into said input port; and
subtracting said first and second potentials.