1. A pneumatic tire comprising:
a tread portion provided with circumferential grooves extending continuously in the circumferential direction of the tire and axial grooves joining the circumferential grooves,
said circumferential grooves including a wavy circumferential groove, and
said axial grooves including first axial grooves joining the wavy circumferential groove so that
at the junction of each of the first axial grooves with the wavy circumferential groove, an acute-angled corner is formed between the first axial groove and the wavy circumferential groove, and
at said junction of each of the first axial grooves, the first axial groove has a toe-side edge intersecting a junction-side side edge of the wavy circumferential groove at a first intersecting point (P1), and a heel-side edge intersecting said junction-side side edge at a third intersecting point (P3), wherein
the first intersecting point (P1) is positioned between a second intersecting point (P2) and one of junction-side maximum amplitude points (RLO) which is positioned adjacently to the second intersecting point (P2) on the heel-side,
the second intersecting point (P2) is an intersecting point between said junction-side side edge and one of maximally-inclined tangents (Ka),
the maximally-inclined tangents (Ka) are tangents to an opposite-of-junction-side side edge of the wavy circumferential groove which are inclined, with respect to the circumferential direction, maximally to the junction-side side edge towards the toe-side,
said junction-side maximum amplitude points (RLO) are points on the junction-side side edge at which the junction-side side edge protrudes maximally towards the junction-side, and
said third intersecting point (P3) is positioned between the second intersecting point (P2) and the junction-side maximum amplitude point (RLO), wherein
said junction-side side edge and said opposite-of-junction-side side edge of the wavy circumferential groove are each formed by a curved line and are substantially parallel with each other, and
there is no groove extending from the junction-side edge other than the first axial grooves which extends axially outwardly to the tread edge while inclining to one circumferential direction at an inclination angle (\u03b1) with respect to the tire circumferential direction, which angle (\u03b1) increases as the axial distance from the wavy circumferential groove is increased, so that the first axial grooves are curved.
2. The pneumatic tire according to claim 1, wherein the angle \u03b81 of the maximally-inclined tangent (Ka) is in a range of from 5 to 25 degrees with respect to the tire circumferential direction.
3. The pneumatic tire according to claim 1, wherein the acute angle \u03b82 between the maximally-inclined tangent (Ka) and a tangent (Kb) to the toe-side edge of the first axial groove at the first intersecting point (P1) is not more than 45 degrees.
4. The pneumatic tire according to claim 1, wherein
the axial distance between the first intersecting point (P1) and an opposite-of-junction-side maximum amplitude point (RR) is in a range of from 2 to 30 mm, wherein
the opposite-of-junction-side maximum amplitude point (RR) is a point on the junction-side edge at which the junction-side edge protrudes maximally towards the opposite-of-junction-side.
5. The pneumatic tire according to claim 1, wherein the width of the first axial groove at the first intersecting point (P1) is in a range of from 50 to 100% of the width of the wavy circumferential groove at the first intersecting point (P1).
6. The pneumatic tire according to claim 1, wherein the width of the first axial groove decreases as the distance from the wavy circumferential groove is increased.
7. The pneumatic tire according to claim 1, wherein
the wavy circumferential groove is disposed on the tire equator,
the first axial grooves are disposed on both sides of the wavy circumferential groove and join both of the edges of the wavy circumferential groove, and
the first axial grooves on both sides of the wavy circumferential groove are arranged in a staggered manner.
8. The pneumatic tire according to claim 1, wherein
the wavy circumferential groove is disposed on each side of the tire equator,
the first axial grooves are disposed axially outside of the wavy circumferential grooves, and
the first axial grooves join only the axially outer edge of each of the wavy circumferential grooves.
9. The pneumatic tire according to claim 1, wherein said circumferential grooves include a straight circumferential groove disposed between the wavy circumferential groove and the tread edge and crossed by said first axial grooves extending from the junction-side edge to the tread edge.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1.-89. (canceled)
90. An electrochemical analyte sensor configured for implantation in vivo and for measuring an analyte concentration in a host, the sensor comprising:
at least one electrode; and
a membrane system located over an electroactive surface of the electrode, wherein the membrane system comprises an interference domain comprising a blend of at least one hydrophilic component and at least one hydrophobic component, wherein the interference domain is configured such that the sensor provides an equivalent analyte signal response, to at least one interferent, that does not substantially affect accuracy of an in vivo analyte concentration measurement, and wherein the sensor provides a linear response to analyte concentration, in vivo, within in a physiological range.
91. The sensor of claim 90, wherein an amount of the hydrophobic component is greater than an amount of the hydrophilic component.
92. The sensor of claim 90, wherein the interference domain is a uni-component domain comprising a polymer, and wherein the blend of at least one hydrophilic component and at least one hydrophobic component comprises at least one hydrophilic substituent of the polymer and at least one hydrophobic substituent of the polymer.
93. The sensor of claim 90, wherein the analyte is glucose, and wherein the sensor is configured to possess a glucose sensitivity of from about 1 nM to about 30 nM.
94. The sensor of claim 90, further comprising sensor electronics operably connected to the electrode and configured to provide a signal representative of an analyte concentration in the host, wherein the analyte is glucose.
95. A method of manufacturing an analyte sensor, comprising:
applying a membrane system to an electroactive surface, wherein the membrane system comprises an interference domain comprising a blend of at least one hydrophilic component and at least one hydrophobic component.
96. The method of claim 95, wherein the step of applying the membrane system comprises applying an electrode domain to the electroactive surface such that the electrode domain is more proximal to the electroactive surface than the interference domain.
97. The method of claim 96, wherein the step of applying the electrode domain comprises depositing at least one layer comprising at least one hydrophilic polymer over the electroactive surface.
98. The method of claim 97, wherein the step of applying the electrode domain comprises depositing at least two layers, each comprising at least one hydrophilic polymer, over the electroactive surface.
99. The method of claim 96, wherein the step of applying the electrode domain comprises depositing polyvinylimidazole or a copolymer thereof.
100. The method of claim 95, wherein the step of applying the membrane system comprises applying the interference domain over the electroactive surface.
101. The method of claim 100, wherein the interference domain possesses a symmetrical structure.
102. The method of claim 100, wherein the step of applying a membrane system comprises providing a solution of at least one hydrophilic component and at least one hydrophobic component in a single solvent, and casting the solution over the electroactive surface.