1. A method for monitoring track strength comprising the steps of:
receiving analog signals from force sensors positioned on axle half shafts of a rail strength measuring axle;
boosting the analog signals from the force sensors;
converting the analog signals from the force sensors to digital values;
calculating lateral and vertical load values based on the digital values;
providing a graphical display of the lateral and vertical load value data points; and
displaying the limits of permissible deviation of values from an envelope of acceptable force;
further including the step of increasing hydraulic force on the rail strength measuring axle when the lateral load value is below a predetermined level to maintain a constant lateral force on the tracks.
2. A method for monitoring track strength comprising the steps of;
receiving analog signals from force sensors positioned on axle half shafts of a rail strength measuring axle;
boosting the analog signals from the force sensors;
converting the analog signals from the force sensors to digital values;
calculating lateral and vertical load values based on the digital values;
providing a graphical display of the lateral and vertical load value data points; and
displaying the limits of permissible deviation of values from an envelope of acceptable force;
further including the step of decreasing hydraulic force on the rail strength measuring axle when the lateral load value is above a predetermined level to maintain a constant lateral force on the tracks.
3. A method for monitoring track strength comprising the steps of:
receiving analog signals from force sensors positioned on axle half shafts of a rail strength measuring axle;
boosting the analog signals from the force sensors;
converting the analog signals from the force sensors to digital values;
calculating lateral and vertical load values based on the digital values;
providing a graphical display of the lateral and vertical load value data points; and
displaying the limits of permissible deviation of values from an envelope of acceptable force;
further including the step of increasing the vertical hydraulic force on the rail strength measuring axle when the vertical load value is below a predetermined level to maintain a constant vertical force on the tracks.
4. A method for monitoring and controlling lateral and vertical forces applied to a medium being tested, the method for monitoring and controlling the lateral and vertical forces on the tested medium comprising the steps of:
receiving analog signals from force sensors positioned within a force application device;
boosting the analog signals from the force sensors;
converting the analog signals from the force sensors to digital values;
calculating lateral and vertical load values based on the digital values;
increasing or decreasing lateral and vertical forces on the tested medium to maintain a substantially constant lateral and vertical force on the tested medium;
providing a graphical display of the lateral and vertical load value data points; and
displaying the limits of permissible deviation of values from an envelope of acceptable force.
5. The method for monitoring and controlling lateral and vertical forces of claim 4 further including the step of receiving video signals from cameras monitoring the tested medium.
6. The method for monitoring and controlling lateral and vertical forces of claim 5 further including the step of storing the video signals.
7. The method for monitoring and controlling lateral and vertical forces of claim 4, further including the steps of receiving and storing input received from an electronic measuring device.
8. The method for monitoring and controlling lateral and vertical forces of claim 4, further including the steps of receiving and storing input received from a electronic counter and associating the counter reading to the lateral and vertical load values.
9. The method for monitoring and controlling lateral and vertical forces of claim 4 wherein the force sensors are in the form of load cells to detect changes in lateral and vertical forces in the force application and detection device.
10. The method for monitoring and controlling lateral and vertical forces of claim 4 wherein the force sensors are in the form of strain gauges used to detect changes in lateral and vertical forces in the force application device.
11. A method for monitoring and controlling forces applied to a medium being tested, the method comprising the steps of:
receiving analog signals from force sensors positioned within a force application and detection device;
boosting the analog signals from the force sensors;
converting the analog signals from the force sensors to digital values;
calculating load values based on the digital values;
increasing or decreasing forces on the tested medium to maintain a substantially constant force on the tested medium;
providing a graphical display of the load values in the form of data points; and
displaying the limits of permissible deviation of values from an envelope of acceptable force, further including the step of receiving video signals from cameras monitoring the tested medium.
12. The method for monitoring and controlling lateral and vertical forces of claim 11 further including the step of storing the video signals.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound of formula (I):
wherein
R1 represents a hydrogen atom, a C1-C6 alkyl group, or a substituted carbonyl group derived from an amino acid, a dipeptide, or a tripeptide;
R2 represents a hydrogen atom or a C1-C6 alkyl group, and, when either one or each of R1 and R2 is an alkyl group, the alkyl group may be substituted with a group selected from the group consisting of a hydroxyl group, an amino group, a halogen atom, a C1-C6 alkylthio group, and a C1-C6 alkoxy group;
R3 represents a C2-C6 alkyl group, a C2-C6 alkenyl group, or a C3-C6 cycloalkyl group;
R4 and R5 each independently represents a hydrogen atom or a C1-C6 alkyl group;
R7 represents a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxycarbonyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, a 3-acetoxy-2-oxobutyl group, a C1-C6 alkyl group, a C2-C7 alkoxymethyl group, or a phenylalkyl group formed of a C1-C6 alkylene group and a phenyl group;
X1 represents a hydrogen atom or a halogen atom; and
A represents a partial structure represented by the following formula (II):
wherein X2 and R6 together form a cyclic structure so as to contain a part of the quinolone nucleus to form a pyridobenzoxazine skeleton of the formula:
wherein the arrow denotes a bond connected with the pyrrolidine ring of formula (I);
or a salt thereof.
2. The compound as described in claim 1 or a salt thereof, wherein the compound of formula (I) is a compound represented by the following formula:
wherein R1, R2, R3, R4, R5, R7, and X1 are as defined in claim 1.
3. The compound as described in claim 1 or a salt thereof, wherein each of R1 and R2 in formula (I) is a hydrogen atom.
4. The compound as described in claim 1 or a salt thereof, wherein one of R1 and R2 in formula (I) is a hydrogen atom, and the other is a methyl group.
5. The compound as described in claim 1 or a salt thereof, wherein R3 in formula (I) is an ethyl group, an n-propyl group, a vinyl group, an isopropyl group, or a cyclopropyl group.
6. The compound as described in claim 1 or a salt thereof, wherein R3 in formula (I) is an ethyl group.
7. The compound as described in claim 1 or a salt thereof, wherein each of R4 and R5 in formula (I) is a hydrogen atom.
8. The compound as described in claim 1 or a salt thereof, wherein X1 in formula (I) is a fluorine atom.
9. The compound as described in claim 1 or a salt thereof, wherein R7 in formula (I) is a hydrogen atom.
10. The compound as described in claim 1 or a salt thereof, wherein a compound of formula (I) is a stereochemically single compound.
11. (3S)-10-(3S,4S)-3-Amino-4-ethylpyrrolidine-1-yl-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido1,2,3-de 1,4benzoxazine-6-carboxylic acid or a salt thereof.
12. A drug containing, as an active ingredient, the compound as recited in claim 1 or a salt thereof.
13. An antibacterial drug containing, as an active ingredient, the compound as recited in claim 1 or a salt thereof.
14. An infectious disease treating drug containing, as an active ingredient, the compound as recited in claim 1 or a salt thereof.
15. A method for producing a drug, comprising incorporating the compound as recited in claim 1 or a salt thereof into a tablet, a powder, a granule, a capsule, a solution, a syrup, an elixir, an oil, or an aqueous suspension.
16. A method for producing an antibacterial drug, comprising incorporating the compound as recited in claim 1 or a salt thereof into a tablet, a powder, a granule, a capsule, a solution, a syrup, an elixir, an oil, or an aqueous suspension.
17. A method for producing an infectious disease treating drug, comprising incorporating the compound as recited in claim 1 or a salt thereof into a tablet, a powder, a granule, a capsule, a solution, a syrup, an elixir, an oil, or an aqueous suspension.