1. A power source cut-off system constructed of: an outlet tap which is connected with a domestic commercial power source to supply electric power to an electrical appliance; and, a telephone set connected with an external telephone line to control said outlet comprising: an outlet with which said electrical appliance is connected; a power source cut-off device for interrupting said power source at said outlet; a receiver means for receiving a radio signal issued from said telephone set; and, a control means for controlling said power source cut-off device on the basis of said radio signal having been received in said receiver means, and wherein said telephone set includes: a control signal receiver means for receiving a control signal having been transmitted through said external telephone line; and, a transmitter means for transmitting said radio signal to said outlet tap on the basis of said control signal receiver means.
2. The power source cut-off system as set forth in claim 1, wherein said outlet tap further comprises: a signal generator means for showing the result of power source cut-off operation carried out with respect to said electrical appliance at said outlet; and, a transmitter means for transmitting said radio signal representing the result of said power source cut-off operation to said telephone set, wherein said telephone set further comprises a receiver means for receiving said radio signal having been transmitted from said transmitter means of said outlet tap.
3. The power source cut-off system as set forth in claim 1, wherein said telephone set further comprises: a voice guide choosing means for choosing a voice guide in report of the result in analysis of the result of said power source cut-off operation on the basis of said radio signal having been received in said receiver means, said power source cut-off operation being conducted in said outlet of said outlet tap; and, a playback means for reproducing said voice guide, wherein said voice guide reports said result to a user having been selected by said voice guide choosing means.
4. A power source cut-off system constructed of: an outlet tap which is connected with a domestic commercial power source to supply electric power to an electrical appliance; and, a telephone set connected in between an external telephone line and a telephone set to control said outlet tap comprising: an outlet with which said electrical appliance is connected; a power source cut-off device for interrupting said power source at said outlet; a receiver means for receiving a radio signal issued from said power source cut-off device; and, a control means for controlling said power source cut-off device on the basis of said radio signal having been received in said receiver means, and wherein said power source cut-off device includes: a control signal receiver means for receiving a control signal having been transmitted through said external telephone line; and, a transmitter means for transmitting said radio signal to said outlet tap on the basis of said control signal receiver means; and, wherein said outlet tap includes: a signal generator means for showing the result in power source cut-off operation of said electrical appliance conducted at said outlet; and, a transmitter means for radio transmitting a radio signal representing said result in power source cut-off operation to said power source cut-off device, said radio signal representing said result in power source cut-off operation being prepared in said signal generator means, wherein said power source cut-off device further includes a receiver means for receiving said radio signal issued from said transmitter means of said outlet tap.
5. The power source cut-off system as set forth in claim 4, wherein said power source cut-off device further comprises: a voice guide choosing means for choosing a voice guide in report of the result in analysis of the result of said power source out-off operation on the basis of said radio signal having been received in said receiver means, said power source cut-off operation being conducted in said outlet of said outlet tap; and, a playback means for reproducing said voice guide, wherein said voice guide reports said result to a user having been selected by said voice guide choosing means.
6. The power source cut-off system as set forth in claim 4, wherein said power source cut-off device comprises: a phone-call reply means for replying a phone call; a confirmation means for confirming whether or not said phone call contains a preset power source cut-off number in reply to said phone call; and, a power source cut-off operation carrying out means for carrying out said power source cut-off operation on the basis of said phone call in the case where said phone call contains said preset power source cut-off number which is confirmed by said confirmation means.
7. A power source cut-off system includes: an outlet tap which is connected with a domestic commercial power source to supply electric power to an electrical appliance; and, a telephone set connected with an external telephone line to control said outlet tap, wherein said outlet tap comprises: an outlet with which said electrical appliance is connected; a power source cut-off device for interrupting said power source at said outlet; a radio receiver which receives a radio signal issued from said telephone set; and, a control circuit section which controls said power source cut-off device on the basis of said radio signal having been received by said radio receiver, and wherein said telephone set includes: a control signal receiver for receiving a control signal having been transmitted through said external telephone line; and, a transmitter which transmits said radio signal to said outlet tap on the basis of said control signal receiver.
8. The radio receiver of claim 7, wherein said receiver comprises a radio communication device.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A sterilized polymeric material for use in a body of a mammal wherein said polymeric material is sterilized by irradiation at a temperature below 25\xb0 C.
2. The sterilized polymeric material of claim 1 which further comprises a therapeutically active agent.
3. The sterilized polymeric material of claim 1 wherein said temperature is at or below about 5\xb0 C.
4. The sterilized polymeric material of claim 2 which comprises polymeric microspheres, microparticles, microcapsules, or implants.
5. The sterilized polymeric material of claim 2 which comprises polymeric microspheres, microparticles, or microcapsules.
6. The sterilized polymeric material of claim 5 which comprises polymeric microparticles.
7. The sterilized polymeric material of claim 5 which comprises polylactide-co-glycolide or polylactic acid.
8. The sterilized polymeric material of claim 5 which comprises polylactide-co-glycolide.
9. The sterilized polymeric material of claim 5 wherein said temperature is below about 15\xb0 C.
10. The sterilized polymeric material of claim 5 wherein said temperature is below about 10\xb0 C.
11. The sterilized polymeric material of claim 5 wherein said composition temperature is at or below about 5\xb0 C.
12. The sterilized polymeric material of claim 5 which is sterilized by gamma irradiation at a dose of about 1.5 to about 4.0 mRad.
13. The sterilized polymeric material of claim 5 wherein said therapeutically active agent comprises a retinoid, a prostaglandin, a tyrosine kinase inhibitor, a glucocorticoid, an androgenic steroid, an estrogenic steroid, a non-estrogenic steroid, an intracellular adhesion molecule inhibitor or an alpha-2-adrenergic agonist.
14. The sterilized polymeric material of claim 5 wherein said therapeutically active agent comprises a retinoid.
15. The sterilized polymeric material of claim 5 wherein said therapeutically active agent comprises tazarotene.
16. A method of sustained delivery of a therapeutically active agent to a mammal comprising administering a sterilized polymeric material comprising said therapeutically active agent to said mammal, wherein the polymeric material is sterilized by irradiation at a temperature below 25\xb0 C.
17. The method of claim 16 wherein the sterilization by irradiation comprises gamma irradiation.
18. The method of claim 17 wherein said temperature is below about 15\xb0 C.
19. The method of claim 17 wherein said temperature is below about 10\xb0 C.
20. The method of claim 17 wherein said temperature is below about 5\xb0 C.
21. The method of claim 17 wherein said temperature is from \u221225\xb0 C. to 5\xb0 C.
22. A method of sterilizing a polymeric material for use in a body of a mammal comprising irradiating said polymeric material at a temperature below 25\xb0 C.
23. The method of claim 22 wherein the polymeric material further comprises a therapeutically active agent.
24. The method of claim 22 wherein said temperature is below about 15\xb0 C.
25. The method of claim 22 wherein said temperature is below about 10\xb0 C.
26. The method of claim 22 wherein said temperature is below about 5\xb0 C.
27. A composition comprising sterilized polymeric microparticles and a therapeutically active agent for use in a body of a mammal wherein said polymeric material is sterilized by irradiation with external cooling of said polymeric material during sterilization.
28. The composition of claim 27 wherein said composition is suitable for sustained delivery of said therapeutically active agent.
29. The composition of claim 27 wherein the temperature of said polymeric material at the end of the sterilization process is about 10\xb0 C. to about 50\xb0 C. lower than said temperature would be in the absence of external cooling.
30. The composition of claim 27 wherein the temperature of said polymeric material at the end of the sterilization process is about 20\xb0 C. to about 50\xb0 C. lower than said temperature would be in the absence of external cooling.
31. The composition of claim 27 wherein the temperature of said polymeric material at the end of the sterilization process is about 50\xb0 C. or more lower than said temperature would be in the absence of external cooling.
32. A method of sterilizing a polymeric material for use in a body of a mammal comprising irradiating said polymeric material with external cooling of the polymeric material.
33. The method of claim 32 wherein the temperature of said polymeric material at the end of the sterilization process is about 10\xb0 C. to about 50\xb0 C. lower than said temperature would be in the absence of external cooling.
34. The method of claim 32 wherein the temperature of said polymeric material at the end of the sterilization process is about 20\xb0 C. to about 50\xb0 C. lower than said temperature would be in the absence of external cooling.
35. The method of claim 32 wherein the temperature of said polymeric material at the end of the sterilization process is about 50\xb0 C. or more lower than said temperature would be in the absence of external cooling.
36. The method of claim 16 wherein the polymeric material comprises polylactide-co-glycolide or polylactic acid.
37. The method of claim 16 wherein the polymeric material comprises polylactide-co-glycolide.
38. The composition of claim 27 wherein the polymeric material comprises polylactide-co-glycolide or polylactic acid.
39. The composition of claim 27 wherein the polymeric material comprises polylactide-co-glycolide.