1. ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
2. A pharmaceutical composition comprising ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
3. A drug for the prevention or treatment of inflammatory diseases comprising ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
4. A drug for the prevention or treatment of dermatitis, atopic dermatitis, contact dermatitis, urticaria, or psoriasis comprising ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
5. A drug for the prevention or treatment of asthma or chronic obstructive pulmonary disease comprising ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
6. A PDE IV inhibitor comprising ()-3-3-(1R,2R,4S)-bicyclo2.2.1hept-2-yloxy-4-methoxyanilino-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A sliding gate regulator comprising:
a valve body having a fluid inlet and a fluid outlet connected by a flow corridor;
an opening disposed in the valve body, the opening being oriented substantially perpendicular to the flow corridor;
a stationary plate disposed within the flow corridor;
a slidable gate disposed within the flow corridor, the slidable gate and the stationary plate cooperating to control fluid flow through the flow corridor; and
a removable plug disposed within the opening in the valve body, the removable plug providing access to the stationary plate and to the slidable gate.
2. The sliding gate regulator of claim 1, wherein the removable plug includes a counter-bore, the counter-bore being oriented substantially perpendicularly to the flow corridor.
3. The sliding gate regulator of claim 2, further comprising a counter spring disposed within the counter-bore.
4. The sliding gate regulator of claim 3, further comprising a counter plug disposed at least partially within the counter-bore, the counter spring biasing the counter plug towards the flow corridor.
5. The sliding gate regulator of claim 4, further comprising a counter pin attached to the counter plug, the counter pin extending towards the flow corridor, the counter pin being operatively connected to the sliding gate.
6. The sliding gate regulator of claim 1, wherein the removable plug is releasably secured to the valve body with a threaded connection.
7. The sliding gate regulator of claim 1, wherein the removable plug includes an outer flange that extends radially outward, the outer flange being disposed distal to the counter-bore.
8. The sliding gate regulator of claim 7, further comprising an o-ring disposed on the outer flange.
9. The sliding gate regulator of claim 1, wherein the slidable gate includes at least one tab extending outward from a side surface.
10. The sliding gate regulator of claim 9, further comprising at least one guiding channel disposed on an inner surface of the valve body, the guiding channel cooperating with the at least one tab to guide the slidable gate during reciprocation.
11. The sliding gate regulator of claim 10, wherein the at least one tab has a rear surface that is substantially flush with a rear surface of the slidable gate.
12. The sliding gate regulator of claim 1, wherein the stationary plate includes an o-ring on a rear surface, the o-ring forming a sealing connection with an inner surface of the valve body.
13. The sliding gate regulator of claim 1, wherein each of the slidable gate and the stationary plate include a plurality of slotted openings.
14. A sliding gate regulator comprising:
a valve body having a fluid inlet and a fluid outlet connected by a flow corridor;
a stationary plate disposed within the flow corridor; and
a slidable gate disposed within the flow corridor, the slidable gate and the stationary plate cooperating to control fluid flow through the flow corridor,
wherein the slidable gate is supported within the flow corridor by opposing biasing elements.
15. The sliding gate regulator of claim 14, wherein at least one of the biasing elements is a biasing spring.
16. The sliding gate regulator of claim 15, wherein both of the opposing biasing elements bias the slidable gate towards a center of the flow corridor.
17. The sliding gate regulator of claim 16, wherein a first biasing spring and a second biasing spring have different spring coefficients.
18. The sliding gate regulator of claim 16, wherein the biasing spring is connected to a pin and plug that are at least partially disposed in a counter-bore of a removable plug.
19. The sliding gate regulator of claim 18, further comprising at least one tab disposed on the slidable gate, the at least one tab cooperating with at least one channel disposed on an inner surface of the valve body.
20. A method of removing a slidable gate or a stationary plate of a sliding gate regulator, the method comprising:
removing a removable plug from a valve body, the removable plug being disposed within an opening in the valve body, the opening being oriented substantially perpendicular to a flow corridor through the valve body; and
withdrawing the slidable gate or the stationary plate through the opening.