1. A composition characterized by comprising a drug of protein derivatives adsorbed on a surface of fine particles of a lactic acid copolymer.
2. The composition according to claim 1, wherein an average diameter of the fine particles is less than 1,000 nanometers.
3. The composition according to claim 1, wherein an average diameter of the fine particles is within a range of 50 to 500 nanometers.
4. The composition according to claim 1, wherein the drug of protein derivatives is an interferon.
5. The composition according to claim 4, wherein the interferon is an interferon-.
6. The composition according to claim 1, wherein the lactic acid copolymer comprises lactic acid units and glycolic acid units.
7. A composition characterized by comprising an interferon- adsorbed on fine particles of a lactic acid copolymer that comprises lactic acid units and glycolic acid units, the fine particles having an average diameter of less than 1,000 nanometers.
8. A scleral plug formed from a composition characterized by comprising a drug of protein derivatives adsorbed on a surface of fine particles of a lactic acid copolymer.
9. The scleral plug according to claim 8, wherein an average diameter of the fine particles is less than 1,000 nanometers.
10. The scleral plug according to claim 8, wherein an average diameter of the fine particles is within a range of 50 to 500 nanometers.
11. The scleral plug according to claim 8, wherein the drug of protein derivatives is an interferon.
12. The scleral plug according to claim 11, wherein the interferon is an interferon-.
13. The scleral plug according to claim 8, wherein the lactic acid copolymer comprises lactic acid units and glycolic acid units.
14. A scleral plug formed from a composition characterized by comprising an interferon- adsorbed on fine particles of a lactic acid copolymer that comprises lactic acid units and glycolic acid units, the fine particles having an average diameter of less than 1,000 nanometers.
15. The scleral plug according to claim 8, wherein a weight average molecular weight of the lactic acid copolymer is within a range of 10,000 to 1,000,000.
16. The scleral plug according to claim 8, wherein a weight average molecular weight of the lactic acid copolymer is within a range of 20,000 to 200,000.
17. The scleral plug according to any one of claims 8 to 16, wherein a compositional molar ratio of the lactic acid units to the glycolic acid units is within a range of 5050 to 1000.
18. The scleral plug according to any one of claims 8 to 16, wherein a compositional molar ratio of the lactic acid units to the glycolic acid units is within a range of 5050 to 8020.
19. The scleral plug according to any one of claims 8 to 16, wherein a compositional molar ratio of the lactic acid units to the glycolic acid units is within a range of 7030 to 8020.
20. A scleral plug formed from a composition comprising a drug of protein derivatives adsorbed on a surface of fine particles of a lactic acid copolymer, the drug being gradually released into a vitreous body.
21. A scleral plug for treatment or prevention of an intraocular diseases, the scleral plug being formed from a composition characterized by comprising a drug of protein derivatives adsorbed on a surface of fine particles of a lactic acid copolymer, the drug being gradually released into a vitreous body.
22. The scleral plug according to claim 21, wherein the intraocular diseases is a retinal disease.
23. The scleral plug according to claim 22, wherein the retinal disease is diabetic retinopathy, macular degeneration, or retinal central vein obstruction.
24. A scleral plug formed from a composition characterized by comprising an interferon- adsorbed on a surface of fine particles of a lactic acid copolymer, the lactic acid copolymer having a compositional molar ratio of lactic acid units to glycolic acid units within a range of 5050 to 1000 and having a weight average molecular weight of 10,000 to 1,000,000, the interferon- being gradually released into a vitreous body.
25. A scleral plug formed from a composition characterized by being formed comprising an interferon- adsorbed on a surface of fine particles of a lactic acid copolymer, the lactic acid copolymer having a compositional molar ratio of lactic acid units to glycolic acid units within a range of 7030 to 8020 and having a weight average molecular weight of 20,000 to 200,000, the interferon- being gradually released into a vitreous body.
26. The scleral plug according to any one of claims 8 to 25, wherein the lactic acid units are in L-, D-, or DL-form.
27. The scleral plug according to any one of claims 8 to 26, manufactured by compression molding.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. Electric exhaler for the vaporization of disinfesting insecticide products, of the type comprising a heating element and a porous support impregnated with an active substance apt to be evaporated at high temperature, characterized in that said heating element is a resistance (R) apt to reach a surface temperature of at least 400 C., and in that said support is a refill (S) of porous ceramic material.
2. Electric exhaler as in claim 1, wherein said ceramic refill (S) is positioned adjacent to said resistance (R) and, preferably, in contact therewith.
3. Electric exhaler as in claim 2, wherein said ceramic refill (S) comprises a first central portion, in tight contact with the resistance (R) and partially surrounding the same.
4. Electric exhaler as in claim 3, wherein said ceramic refill (S) also comprises a second, peripheral, portion consisting of one or more wings projecting from said first portion, to rest the ceramic support (S) onto the structure of the electric exhaler.
5. Electric exhaler as in claim 4, wherein said resistance (R) has the shape of a straight cylinder, and said ceramic refill (S) consists of a cylindrical body whose generating lines are parallel to the axis of the resistance (R) and the cross-section of which has a -shape.
6. Electric exhaler as in claim 5, wherein the inner radius of the curved portion of said -shape corresponds to the outer radius of said resistance (R).
7. Electric exhaler as in claim 5, wherein said ceramic refill (S) bears, with the wings of its -shape, onto a plurality of vertical rods (3) projecting from the base (1) of the electric exhaler and formed, in one piece therewith, of a heat-resisting plastic material.
8. Electric exhaler as in claim 3, wherein said resistance (R) has the shape of a straight cylinder, and said ceramic refill (S) consists of a cylindrical body whose generating lines are parallel to the axis of the resistance (R) and the cross-section of which has a C-shape the inner radius of which corresponds to the outer radius of said resistance (R).
9. Electric exhaler as in any one of the previous claims, wherein said resistance (R) is fixed to the central portion of a metallic heatsink (5), the arms (5a, 5b) of which are fixed to the structure of the electric exhaler.
10. Electric exhaler as in claim 9, wherein the arms (5a, 5b) of the metallic heatsink (5) are fixed to supports (4, 6) projecting from the base (1) andor from the cap (2) of the electric exhaler and formed, in one piece therewith, of a heat-resisting plastic material.
11. Electric exhaler as in claim 9, wherein a portion (5c) of said metallic heatsink (5) is associated to a bimetallic thermostat (7), so as to transfer to said thermostat part of the heat transmitted by said resistance (R).
12. Electric exhaler as in claim 11, wherein said bimetallic thermostat (7) is apt to interrupt the power supply to the resistance (R) after a preset period of operating time of said resistance.
13. Electric exhaler as in claim 11 or 12, wherein said bimetallic thermostat (7) is of the manual resetting type, or of the self-hold type.
14. Electric exhaler as in any one of the previous claims, wherein said resistance (R) is apt to reach a surface temperature of at least 500 C. and, preferably, a temperature of 600 C.