1. A composition comprising a silicone-polyoxamide process additive and a thermoplastic with the proviso that the silicone-polyoxamide process additive is not acrylic modified;
wherein the refractive index difference between the silicone-polyoxamide process additive and the thermoplastic is less than about 0.07; and
wherein the weight percent of silicone-polyoxamide process additive based on the total weight of the composition is an amount effective to reduce extrusion melt defects in the thermoplastic.
2. (canceled)
3. The composition of claim 1 wherein the silicone-polyoxamide process additive is selected from:
(a) at least one copolymer comprising at least two repeat units of Formula I-a:
(b) at least one copolymer comprising at least two repeat units of Formula I-b:
(c) and combinations thereof
wherein each R1 is independently an alkyl, haloalkyl, aralkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; each Y is independently an alkylene, aralkylene, or a combination thereof; G is a divalent residue; each group B is selected from a covalent bond, an alkylene of 4-20 carbons, an aralkylene, an arylene, or a combination thereof; n is an integer of 0 to 1500; and p is an integer of 1 to 10.
4. The composition of claim 3 wherein the divalent residue is derived from a diamine having the formula R3HN-G-NHR3, wherein R3 is selected from a hydrogen and an alkyl.
5. The composition of claim 4 wherein the diamine is a heterocyclic group.
6. The composition of claim 1 wherein the silicone-polyoxamide process additive has a molecular weight greater than 50,000.
7. The composition of claim 1 wherein the silicone-polyoxamide process additive polymer has a viscosity of greater than 3160 Pa.
8. The composition of claim 1 wherein the weight percent of the silicone-polyoxamide process additive based on the total weight of the composition is 0.01 wt % to 5.0 wt %.
9. The composition of claim 1 wherein the weight percent of the silicone-polyoxamide process additive is 0.01 wt % to 1.0% wt %.
10. The composition of claim 1 further comprising a synergist.
11. The composition of claim 10 wherein the synergist is i) silicone-polyether copolymers; ii) aliphatic polyesters; iii) aromatic polyesters; iv) polyether polyols; and v) poly(oxyalkylene) polymers.
12. The composition of claim 1 wherein the thermoplastic is selected from polypropylenes, polystyrenes, polyethylenes, polyesters, and combinations thereof.
13. The composition of claim 12 wherein the thermoplastic is a polypropylene.
14. (canceled)
15. An article comprising the composition of claim 1, wherein the article is an extruded film, a bottle, a sheet or a tube.
16. A method of making the article of claim 15 comprising:
a. melt mixing the thermoplastic and the silicone-polyoxamide process additive to form a mixture;
b. extruding the mixture.
17. The method of claim 16 wherein the melt mixing step is done by batch blending or extrusion.
18. The method of claim 16 wherein the silicone-polyoxamide process additive is selected from
(a) at least one copolymer comprising at least two repeat units of Formula I-a:
(b) at least one copolymer comprising at least two repeat units of Formula I-b:
(c) and combinations thereof
wherein each R1 is independently an alkyl, haloalkyl, aralkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; each Y is independently an alkylene, aralkylene, or a combination thereof; G is a divalent residue; each group B is selected from a covalent bond, an alkylene of 4-20 carbons, an aralkylene, an arylene, or a combination thereof; n is an integer of 0 to 1500; and p is an integer of 1 to 10.
19. The method of claim 18 wherein the divalent residue is derived from a diamine having the formula R3HN-G-NHR3, wherein R3 is selected from a hydrogen and an alkyl,
20. The method of claim 19 wherein the diamine is a heterocyclic group.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A system for delivering a coated reconfigurable medical implant to a target site, the system comprising:
a carrier device, the carrier device having a proximal end and a distal end, the distal end having an implant carrying region; and
a reconfigurable deployable coated medical implant in physical communication with the implant carrying region of the carrier device,
the deployable medical implant coated with a coating having therapeutic,
the coating positioned on an exposed surface of the deployable medical implant,
the deployable medical implant reconfigurable from a first expanded configuration to a second contracted configuration,
the therapeutic encased by an encasing hollow deformable membrane,
the membrane, in an unexpanded state, defining a cavity having a cross-section that is smaller than the external cross-section of the deployable medical implant when the medical implant is in its second contracted configuration.
2. The system of claim 1 wherein the reconfigurable deployable medical implant is either a stent, a graft, a stent graft, or a vena cava filter.
3. The system of claim 1 wherein,
the medical implant comprises a frame,
the frame expandable from a first configuration to a second configuration,
the frame having the coating on an external outward facing surface, and
an internal surface of the deformable membrane is in contact with the coating on an external outward facing surface of the medical implant.
4. The system of claim 3 wherein the frame is in communication with a first sock, the sock sized to secure the frame to the implant carrying region of the carrier device, the first sock positioned at an end of the frame.
5. The system of claim 4 wherein the frame is in communication with a second sock,
the second sock at an end of the frame opposite the end of the frame in communication with the first sock,
the second sock sized to secure the frame to the implant carrying region of the carrier device.
6. The system of claim 1 wherein the deformable membrane includes a zip chord,
the zip chord having an accessible graspable portion extending from the deformable membrane.
7. The system of claim 1 wherein the deformable membrane has a cylindrically shaped portion.
8. The system of claim 1 wherein the deformable membrane defines a vessel with a single orifice.
9. The system of claim 1 wherein the deformable membrane has a thickness substantially between 0.3 mm and 0.6 mm.
10. The system of claim 1 wherein the deformable membrane defines a sleeve having a first orifice and a second orifice.
11. The system of claim 1 wherein the deformable membrane also covers at least a portion of a first sock,
the first sock sized to position the medical implant at the implant carrying region of the carrier device.
12. The system of claim 11 wherein the deformable membrane also covers at least a portion of a second sock,
the first sock at an end of the medical implant and the second sock at a different end of the medical implant.
13. The system of claim 1 wherein the carrier device is a balloon catheter.
14. The system of claim 1 wherein the deformable membrane includes an external coating along an outside exposed surface of the deformable membrane.
15. The system of claim 1 wherein the deformable membrane is covered with a protective covering.
16. The system of claim 15 wherein the protective covering is a monofilament nylon braided sleeve.