1. A method of lowering blood pressure in an individual in need thereof comprising administering to the individual an effective amount of a compound selected from the group consisting of Compound Nos. 6, 9 to 12, 14, 16 to 21, 23 to 28, 39 to 40, 42, 44 to 59, 63 to 72, 77 to 82, 104, 108 to 116, 118 to 131, 133 to 142, 144 to 171, 173 to 179, 187 to 192, 195 to 198, 220, 269 to 271, 273 to 287, 290 to 306, 308 to 319, 321 to 338, 340 to 342, II-1 to II-4, II-6 to II-16, II-18 to II-19, II-39 to II-40, II-58 to II-65, II-67 to II-68, II-70 to II-71, II-75 to II-77, II-80 to II-84, II-88 to II-94, II-96 to II-106, II-108 to II-118, II-120 to II-121, II-123 to II-125, II-127 to II-128, II-130 to II-136, II-138 to II-154, II-188 to II-206, II-212 to II-213, II-215, II-220 to II-227, II-229 to II-232, II-240, II-243 to II-253, II-255 to II-269, II-271 to II-272, II-274, II-276 to II-285, II-287 to II-291, II-293 to II-298, IV1, IV-8 to IV-9, IV-11 to IV-18, IV-49 to IV-58, IV-91, IV-93 to IV-98, IV129 to IV-138, IV-169 to IV-178, IV-209 to IV-211, IV-213 to IV-218, and V-1 to V-23; or a salt, solvate or N-oxide thereof.
2. A method of (i) increasing renal blood flow, andor (ii) decreasing sodium reabsorption, in an individual in need thereof comprising administering to the individual an effective amount of a compound selected from the group consisting of Compound Nos. 6, 9 to 12, 14, 16 to 21, 23 to 28, 39 to 40, 42, 44 to 59, 63 to 72, 77 to 82, 104, 108 to 116, 118 to 131, 133 to 142, 144 to 171, 173 to 179, 187 to 192, 195 to 198, 220, 269 to 271, 273 to 287, 290 to 306, 308 to 319, 321 to 338, 340 to 342, II-1 to II-4, II-6 to II-16, II-18 to II-19, II-39 to II-40, II-58 to II-65, II-67 to 11-68, II-70 to II-71, II-75 to II-77, II-80 to II-84, II-88 to II-94, II-96 to II-106, II-108 to II-118, II-120 to II-121, II-123 to II-125, II-127 to II-128, II-130 to II-136, II-138 to II-154, II-188 to II-206, II-212 to II-213, II-215, II-220 to II-227, II-229 to II-232, II-240, II-243 to II-253, II-255 to II-269, II-271 to II-272, II-274, II-276 to II-285, II-287 to II-291, II-293 to II-298, IV1, IV-8 to IV-9, IV-11 to IV-18, IV-49 to 1V-58, IV-91, IV-93 to IV-98, IV129 to IV-138, IV-169 to IV-178, IV-209 to IV-211, IV-213 to IV-218, and V-1 to V-23; or a salt, solvate or N-oxide thereof.
3. A method of treating a disease or condition that is responsive to any one or more of: (i) a decrease in blood pressure; (ii) an increase in renal blood flow; and (iii) a decrease of sodium reabsorption, comprising administering to an individual in need thereof an effective amount of a compound selected from the group consisting of Compound Nos. 6, 9 to 12, 14, 16 to 21, 23 to 28, 39 to 40, 42, 44 to 59, 63 to 72, 77 to 82, 104, 108 to 116, 118 to 131, 133 to 142, 144 to 171, 173 to 179, 187 to 192, 195 to 198, 220, 269 to 271, 273 to 287, 290 to 306, 308 to 319, 321 to 338, 340 to 342, II-1 to II-4, II-6 to II-16, II-18 to II-19, II-39 to II-40, II-58 to II-65, II-67 to 11-68, II-70 to II-71, II-75 to II-77, II-80 to II-84, II-88 to II-94, II-96 to II-106, II-108 to II-118, II-120 to II-121, II-123 to II-125, II-127 to II-128, II-130 to II-136, II-138 to II-154, II-188 to II-206, II-212 to II-213, II-215, II-220 to II-227, II-229 to II-232, II-240, II-243 to II-253, II-255 to II-269, II-271 to II-272, II-274, II-276 to II-285, II-287 to II-291, II-293 to II-298, IV1, IV-8 to 1V-9, 1V-11 to IV-18, IV-49 to IV-58, IV-91, IV-93 to IV-98, IV129 to IV-138, IV-169 to IV-178, IV-209 to IV-211, IV-213 to IV-218, and V-1 to V-23; or a salt, solvate or N-oxide thereof.
4. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
5. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
6. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
7. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
8. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
9. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
10. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
11. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
12. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
13. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
14. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
15. The method of any one of claims 1, 3, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
16. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
17. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
18. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
19. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
20. The method of any one of claims 1, 2, and 3, wherein the compound is selected from the group consisting of:
or a salt thereof.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A double-winged radiator for CPU, comprising:
two sets of first radiator fins being made of a material having a high heat transfer capacity, and provided at a predetermined position with at least one through hole;
at least one heat-transfer tube extended through said at least one through hole provided on said two sets of first radiator fins, so that said two sets of first radiator fins are separately fixedly located at two outer ends of said at least one heat-transfer tube; and
a heat-transfer block being made of a material having a high heat transfer capacity, and provided at a top with a receiving portion, in which a section of said at least one heat-transfer tube between said two sets of first radiator fins is seated; and
said heat-transfer block being mounted on an upper side of a central processing unit (CPU) to transfer heat produced by said CPU during an operation thereof via said at least one heat-transfer tube to said two sets of first radiator fins that provide a large radiating area and therefore enable heat transferred thereto to quickly dissipate therefrom;
further comprising a locating member having a projection downward extended from a lower middle portion thereof, and a recess portion being provided on a top of each of said two sets of first radiator fins for receiving two outer ends of said locating member while said downward extended projection of said locating member is located between said two sets of first radiator fins.
2. The double-winged radiator for CPU as claimed in claim 1, wherein said heat-transfer tube is more than one in number.
3. The double-winged radiator for CPU as claimed in claim 1, wherein said heat-transfer block is preferably made of a copper material.
4. The double-winged radiator for CPU as claimed in claim 1, further comprising one set of second radiator fins located between said two sets of first radiator fins, said set of second radiator fins being provided at a lower side with an engaging portion for engaging with said at least one heat-transfer tube, so as to provide increased radiating area and radiating efficiency for said double-winged radiator for CPU.
5. The double-winged radiator for CPU as claimed in claim 1, wherein said receiving portion on the top of said heat-transfer block comprises at least one groove corresponding to and receiving said at least one heat-transfer tube therein.
6. The double-winged radiator for CPU as claimed in claim 1, wherein said receiving portion on the top of said heat-transfer block comprises at least one pair of two rows of protuberances, and a distance between said two rows of protuberance corresponding to said at least one heat-transfer tube for receiving said heat-transfer tube therein.