1. A printing apparatus which prints an image on the basis of received image data, comprising:
a mounting unit in which a storage medium storing the image data is mounted;
a terminal for connecting an image supply device for supplying the image data;
processing means for processing the image data input via the mounting unit or the terminal;
an operation unit adapted to be operated by a user and input an instruction and data;
detection means for detecting whether the image supply device has been connected via the terminal;
invalidation means for invalidating input of the image data from the storage medium mounted in the mounting unit and operation on the operation unit when said detection means detects that the image supply device has been connected;
image print control means for printing the image on the basis of the image data from the image supply device;
interface means for connecting a host computer; and
means for permitting access from the host computer to the storage medium via said interface means even when said detection means detects the image supply device has been connected.
2. The apparatus according to claim 1, wherein the printing apparatus further comprises a display unit for displaying the image to be printed, and said invalidation means invalidates the image display on the display unit when said detection means detects that the image supply device has been connected.
3. The apparatus according to claim 2, wherein the display unit is detachable from a main body of the printing apparatus.
4. The apparatus according to claim 1, wherein the operation unit comprises a display, and the printing apparatus further comprises display control means for displaying a predetermined image on the display when said detection means detects that the image supply device has been connected.
5. The apparatus according to claim 1, wherein the image supply device includes a digital camera.
6. A printing apparatus which prints an image on the basis of received image data comprising:
a mounting unit in which a memory card storing image data is mounted;
a first terminal for connecting an image supply device for supplying sensed image data:
a second terminal for connecting a computer device;
image processing means for processing the image data input via the mounting unit or the first terminal;
an operation unit adapted to be operated by a user and input an instruction and data;
detection means for detecting whether or not the image supply device has been connected via the first terminal;
invalidation means for invalidating input of image data from the memory card mounted in the mounting unit and operation on the operation unit when said detection means detects that the image supply device has been connected;
print control means for controlling to print an image on the basis of the image data from the image supply device;
interface means for connecting a host computer; and
means for permitting access from the host computer to the memory card via said interface means even when said detection means detects the image supply device has been connected.
7. A printing apparatus which prints an image on the basis of received image data, comprising:
a mounting unit in which a memory card storing image data is mounted;
a first terminal for connecting an image supply device for supplying image data;
a second terminal for connecting a computer device;
image processing means for processing the image data input via the mounting unit or the first terminal;
an operation unit adapted to be operated by a user and input an instruction and data;
detection means for detecting whether or not the image supply device has been connected via the first terminal;
selection means for selecting which of the memory card, the image supply device, and the computer device is given priority for data processing;
print control means for controlling to print an image on the basis of image data from one of the memory card, the image supply device, and the computer device, which is selected by said selection means;
interface means for connecting a host computer; and
means for permitting access from the host computer to the memory card device via said interface means even when said detection means detects the image supply device has been connected.
8. A control method of controlling a printing apparatus for printing an image on the basis of received image data, comprising:
a detection step of detecting whether an image supply device has been connected;
an invalidation step of invalidating input of the image data from a mounted storage medium and user operation on an operation unit when connection of the image supply device is detected in said detection step;
a print control step of controlling to print the image on the basis of the image data from the image supply device; and
a step of permitting access from a host computer to the storage medium even when connection of the image supply device is detected in said detection step.
9. The method according to claim 8, wherein in said invalidation step, an image display on a display unit is invalidated when connection of the image supply device is detected in said detection step.
10. The method according to claim 9, wherein the display unit is detachable from a main body of the printing apparatus.
11. The method according to claim 8, further comprising a display control step of displaying a predetermined image when connection of the image supply device is detected in said detection step.
12. The method according to claim 8, wherein the image supply device includes a digital camera.
13. A computer readable storage medium storing a program for executing the control method defined in claim 8.
14. A program stored on a computer executable medium which executes the control method defined in claim 8.
15. A control method for a printing apparatus for printing an image on the basis of received image data, comprising:
a detection step of detecting whether an image supply device has been connected via a first terminal for connecting the image supply device for supplying the image data;
an invalidation step of, when connection of the image supply device is detected in said detection step, invalidating input of the image data from a memory card mounted in a mounting unit for mounting the memory card storing image data, and operation on an operation unit which is operated by a user and inputs an instruction and data;
a print control step of controlling to print an image on the basis of image data from the image supply device in accordance with an operation on the image supply device; and
a step of permitting access from a host computer to the memory card even when connection of the image supply device is detected in said detection step.
16. A control method for a printing apparatus for printing an image on the basis of received image data, comprising:
a detection step of detecting whether or not an image supply device has been connected via a first terminal for connecting the image supply device for supplying the image data;
a selection step of selecting which of a memory card, the image supply device, and a computer device is given priority for data processing;
a print control step of controlling to print the image on the basis of one of the image data from the memory card, the image supply device, and the computer device, which is selected in said selection step; and
a step of permitting access from a host computer to the memory card even when connection of the image supply device is detected in said detection step.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A recombinant adenovirus comprising: a liver tissue-specific phosphoenolpyruvate carboxykinase (PEPCK) gene promoter; a trans-splicing ribozyme operably linked to the promoter and acting on a cancer-specific gene; a therapeutic gene or reporter gene linked to a 3\u2032 exon of the ribozyme; and a serotype 35 fiber knob and serotype 5 shaft, the recombinant adenovirus lacking adenovirus E1, E3 and E4 orf1 to orf4 genes.
2. The recombinant adenovirus of claim 1, wherein the liver tissue-specific PEPCK gene promoter has a nucleotide sequence set forth in SEQ ID NO: 1.
3. The recombinant adenovirus of claim 1, wherein the promoter further comprises an ApoAl intron having a nucleotide sequence set forth in SEQ ID NO: 2.
4. The recombinant adenovirus of claim 1, wherein the cancer-specific gene is hTERT (human telomerase reverse transcriptase) mRNA, AFP (alphafetoprotein) mRNA, CEA (carcinoembryonic antigen) mRNA, PSA (prostate-specific antigen) mRNA, or CKAP2 (cytoskeleton-associated protein 2) mRNA.
5. The recombinant adenovirus of claim 1, wherein the ribozyme is a trans-splicing group I ribozyme that specifically targets hTERT (human telomerase reverse transcriptase) mRNA.
6. The recombinant adenovirus of claim 1, wherein the therapeutic gene is any one selected from the group consisting of drug-sensitizing genes, proapoptotic genes, cytostatic genes, cytotoxic genes, tumor suppressor genes, antigenic genes, cytokine genes, and anti-angiogenic genes.
7. The recombinant adenovirus of claim 1, wherein the reporter gene is a gene that encodes LacZ, CAT (chloramphenicol acetyl transferase), Renila luciferase, firefly luciferase, red fluorescent protein (RFP), green fluorescent protein (GFP), secreted placental alkaline phosphatase (SEAP) or HSV-tk (Herpes simplex virus-thymidine kinase).
8. The recombinant adenovirus of claim 1, further comprising an ApoE (apolipoprotein E) gene enhancer set forth in SEQ ID NO: 6, a PEPCK (phosphoenolpyruvate carboxykinase) gene enhancer, a serum albumin gene enhancer, an AFP (alphafetoprotein) gene enhancer, a CEA (carcinoembryonic antigen) gene enhancer, or a PSA (prostate-specific antigen) gene enhancer.
9. The recombinant adenovirus of claim 1, wherein the trans-splicing ribozyme has a nucleotide sequence set forth in SEQ ID NO: 3.
10. The recombinant adenovirus of claim 1, wherein the therapeutic gene is a HSV-tk (herpes simplex virus-thymidine kinase) gene having a nucleotide sequence set forth in SEQ ID NO: 4.
11. A pharmaceutical composition for treating liver cancer, which comprises, as an active ingredient, a recombinant adenovirus set forth in claim 1.
12. A composition for diagnosing liver cancer, which comprises, as an active ingredient, a recombinant adenovirus set forth in claim 1.
13. A method of treating liver cancer, the method comprising administering a pharmaceutically acceptable amount of the recombinant adenovirus set forth in claim 1 to a subject in need of treatment.