1. A resin composition comprising 3.0 to 7.0 parts by weight of an acryl-modified polyorganosiloxane (component B) based on 100 parts by weight of an aromatic polycarbonate resin (component A), wherein
the acryl-modified polyorganosiloxane (component B) is obtained by graft copolymerizing a polyorganosiloxane (component B1) represented by the following formula (1) with a mixture (component B2) of 70 to 100 wt % of a (meth)acrylic ester (component B2-1) and 0 to 30 wt % of another copolymerizable monomer (component B2-2) in a (component B2component B1) weight ratio of 595 to 955.
(in the above formula, R1, R2 and R3 are each independently a hydrocarbon group having 1 to 20 carbon atoms or halogenated hydrocarbon group having 1 to 20 carbon atoms, Y is a radical reactive group selected from the group consisting of vinyl group, allyl group and \u03b3-(meth)acryloxypropyl group, X1 and X2 are each independently a hydrogen atom, alkyl group having 1 to 4 carbon atoms or group represented by \u2014SiR4R5R6 (R4 and R5 are each independently a hydrocarbon group having 1 to 20 carbon atoms or halogenated hydrocarbon group having 1 to 20 carbon atoms, and R6 is a hydrocarbon group having 1 to 20 carbon atoms, halogenated hydrocarbon group having 1 to 20 carbon atoms or radical reactive group selected from the group consisting of vinyl group, allyl group and \u03b3-(meth)acryloxypropyl group), m is a positive integer of 10,000 or less, and n is an integer of 1 to 500.)
2. The resin composition according to claim 1, wherein the component B2-1 is methyl methacrylate andor 2-hydroxyethyl methacrylate.
3. The resin composition according to claim 1, wherein the weight ratio of the component B2 to the component B1 is 2080 to 6040.
4. The resin composition according to claim 1 which comprises 0.005 to 0.6 part by weight of an organic metal salt-based flame retardant (component C) based on 100 parts by weight of the aromatic polycarbonate resin (component A).
5. The resin composition according to claim 4, wherein the organic metal salt-based flame retardant (component C) is an alkali (earth) metal salt of an organic acid.
6. The resin composition according to claim 5, wherein the alkali (earth) metal salt of an organic acid (component C) is an alkali (earth) metal salt of an organic sulfonic acid.
7. The resin composition according to claim 1 which comprises 4.0 to 9.0 parts by weight of an organic phosphorus compound-based flame retardant (component D) based on 100 parts by weight of the aromatic polycarbonate resin (component A).
8. The resin composition according to claim 1 which comprises 0.01 to 1 part by weight of a fluorine-containing dripping inhibitor (component E) based on 100 parts by weight of the aromatic polycarbonate resin (component A).
9. The resin composition according to claim 1 which comprises 4.0 to 9.0 parts by weight of an organic phosphorus compound-based flame retardant (component D) and 0.01 to 1 part by weight of a fluorine-containing dripping inhibitor (component E) based on 100 parts by weight of the aromatic polycarbonate resin (component A).
10. The resin composition according to claim 7, wherein the organic phosphorus compound-based flame retardant (component D) is a phosphate represented by the following formula (2).
(In the above formula, X is a diphenol residue derived from a dihydroxy compound selected from the group consisting of hydroquinone, resorcinol, bis(4-hydroxydiphenyl)methane, bisphenol A, dihydroxydiphenyl, dihydroxynaphthalene, bis(4-hydroxyphenyl)sulfone, bis(4-hydroxyphenyl)ketone and bis(4-hydroxyphenyl)sulfide, j, k, l and m are each independently 0 or 1, and n is an integer of 0 to 5 (n is an average value in the case of a mixture of phosphates having different degrees n of polymerization), and R11, R12, R13 and R14 are each independently a monophenol residue derived from an aryl group selected from the group consisting of phenol, cresol, xylenol, isopropylphenol, butylphenol and p-cumylphenol which may be substituted by a halogen atom.
11. A molded article comprises the resin composition of claim 1.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A method for the treatment of cystic fibrosis, comprising administering to a subject in need thereof a pharmaceutically acceptable amount of a glucosidase inhibitor, wherein said inhibitor is a compound having the following formula:
NB-DMJ (N-butyldeoxymannojirimycin).
2. The method of claim 1, wherein the inhibitor is administered by oral, rectal or nasal route.
3. The method of claim 1, wherein the inhibitor is administered in an amount of 1 mg to 2 g per day for adults, or 1 mg to 1 g per day for children and infants, in one or more doses.
4. The method of claim 1, wherein the inhibitor is administered in a form selected from the group consisting of: syrup, suspension, gelatine capsules, tables, powder, granules, suppositories, aerosol by inhalation, and drops.