1. A package comprising:
one or more surfaces; and
a first flexure having a first base attached to the one or more surfaces, the first flexure having a body coupled to a plurality of legs via flexing spring regions, the flexing spring regions enabling legs of the plurality of legs on opposite sides of the body to spread further apart in response to a force on the body when not attached to the one or more surfaces; and
at least two optical elements coupled to the first base of the flexure, the first base having at least one vertical surface to mount an optical element thereon perpendicular to an optical axis, wherein the optical element is one selected from the group that includes a laser, a lens, a modulator, a filter, a beam splitter, an isolator, a polarizer, a detector, and a grating.
2. The package in claim 1 further comprising a second flexure, wherein the second flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and
a second base having a vertical surface to mount a first optical element and a channel having an opening opposite the vertical surface on the second base for coupling a second optical element.
3. The package in claim 2 wherein the second base further comprises subtracted radius corners for handling the flexure.
4. The package in claim 1 further comprising a second flexure, wherein the second flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal
surface; and
a second base having an inverted U-shape draping over the optical component support with a least one vertical surface to mount an optical element.
5. The package in claim 4 wherein the second base includes a horizontal surface and a plurality corners of the base have extracted circular regions for handling.
6. The package in claim 1 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a cube with an opening along the optical axis and including one or more vertical surfaces for mounting optical elements.
7. The package in claim 1 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped portion with an extension having a vertical surface to mount the optical element thereon and a horizontal extension to mount the optical element thereon.
8. The package in claim 1 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped base with a spherical radius top with a horizontal surface thereon for suction handling, wherein the rod-shaped base includes a vertical surface for mounting the optical element thereon and curved side surfaces for handling.
9. The package in claim 1 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a C-shaped base with a vertical surface to mount the optical element as well as a cavity the opposite side of the first base in relation to the vertical surface, the cavity for mounting an optical element.
10. The package in claim 1 wherein the at least two optical elements are aligned with an optical axis.
11. The package of claim 1 wherein the first base includes a semi-circular portion.
12. The package of claim 11 further comprising a flat handling surface on the semi-circular portion.
13. The package of claim 1 wherein the first base further comprises a groove for attaching an optical fiber.
14. The package in claim 13 wherein the first base further includes at least two surfaces to attach the at least two optical elements.
15. A package comprising:
one or more surfaces;
a first flexure having a first base attached to the one or more surfaces, a body,
a plurality of legs coupled to the body via flexing spring regions, the flexing spring regions enabling legs of the plurality of legs on opposite sides of the body to spread further apart in response to a force on the body when not attached to the one or more surfaces, and
at least a pair of handling features; and
at least two optical elements coupled to the first base of the flexure and aligned with an optical axis, the first base having at least one vertical surface to mount an optical element thereon perpendicular to the optical axis, wherein the optical element is one selected from the group that includes a laser, a lens, a modulator, a filter, a beam splitter, an isolator, a polarizer, a detector, and a grating.
16. The package in claim 15 further comprising a second flexure wherein the second flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and
a second base having a vertical surface to mount a first optical element and a channel having an opening opposite the vertical surface on the second base for coupling a second optical element.
17. The package in claim 16 wherein the second base further comprises subtracted radius corners for handling the flexure.
18. The package in claim 15 further comprising a second flexure, wherein the second flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and
a second base having an inverted U-shape draping over the optical component support with a least one vertical surface to mount an optical element.
19. The package in claim 18 wherein the second base includes a horizontal surface and a plurality corners of the base have extracted circular regions for handling.
20. The package in claim 15 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a cube with an opening along the optical axis and including one or more vertical surfaces for mounting optical elements.
21. The package in claim 15 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped portion with an extension having a vertical surface to mount the optical element thereon and a horizontal extension to mount the optical element thereon.
22. The package in claim 15 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped base with a spherical radius top with a horizontal surface thereon for suction handling, wherein the rod-shaped base includes a vertical surface for mounting the optical element thereon and curved side surfaces for handling.
23. The package defined in claim 15 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the base comprises a C-shaped base with a vertical surface to mount the optical element as well as a cavity the opposite side of the first base in relation to the vertical surface, the cavity for mounting the optical element.
24. The package of claim 15 wherein the first base includes a semi-circular portion.
25. The package of claim 24 further comprising a flat handling surface on the semi-circular portion.
26. The package of claim 15 wherein the first base further comprises a groove for attaching an optical fiber.
27. The package defined in claim 26 wherein the first base further includes at least two surfaces to attach the at least two optical elements.
28. A package comprising:
one or more surfaces;
a first flexure having a first base attached to the one or more surfaces, a body,
two pairs of legs coupled to the body via flexing spring regions, the flexing spring regions enabling legs of the two pairs of legs on opposite sides of the body to spread further apart in response to a force on the body when not attached to the one or more surfaces, and
at least a pair of handling features; and
at least two optical elements coupled to the first base of the flexure and aligned with an optical axis, the first base having at least one vertical surface to mount an optical element thereon perpendicular to the optical axis, wherein the optical element is one selected from the group that includes a laser, a lens, a modulator, a filter, a beam splitter, an isolator, a polarizer a detector, and a grating.
29. The package in claim 28 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped portion with an extension having a vertical surface to mount the optical element thereon and a horizontal extension to mount the optical element thereon.
30. The package in claim 28 wherein the first flexure comprises:
an optical component support having a pair of legs on opposite sides of a horizontal surface with a flexing spring region between each leg and the horizontal surface; and wherein the first base comprises a rod-shaped base with a spherical radius top with a horizontal surface thereon for suction handling, wherein the rod-shaped base includes a vertical surface for mounting the optical element thereon and curved side surfaces for handling.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A pharmaceutically acceptable salt of N-4-(1-cyanocyclopentyl)phenyl-2-(4-pyridylmethyl)amino-3-pyridine carboxamide.
2. The compound according to claim 1, wherein the salt is an inorganic salt.
3. The compound according to claim 1, wherein the salt is an organic salt.
4. The compound according to claim 1, wherein the salt is selected from the group consisting of mesylate salt, maleate salt, tartrate salt, succinate salt, acetate salt, trifluoroacetate salt, fumarate salt, citrate salt, benzene sulfonate salt, benzoate salt, naphthalene sulfonate salt, lactate salt, and malate salt.
5. The compound according to claim 1, wherein the salt is selected from the group consisting of hydrochloride salt, hydrobromide salt, sulphate salt, nitrate, and phosphate salt.
6. The compound according to claim 1, wherein the salt is mesylate salt.
7. The compound according to claim 1, wherein the salt is hydrochloride salt.
8. A pharmaceutical composition comprising a therapeutically effective amount of the compounds according to any one of claims 1-7, and one or more pharmaceutically acceptable carrier(s).
9. A use of the compounds according to any one of claims 1-7 in the preparation of an antineoplastic medicament.
10. A process for the preparation of the compounds according to any one of claims 1-7, comprising the step of forming the salt of N-4-(1-cyanocyclopentyl)phenyl-2-(4-pyridylmethyl) amino-3-pyridine carboxamide with a corresponding acid.