1. A method of treating the central nervous system, comprising administering an effective amount of an IGF structural analog to treat or prevent neuronal damage in the central nervous system.
2. The method of claim 1, wherein the neuronal damage to the central nervous system is due to a disorder or disease in the post-birth brain or spinal cord.
3. The method of claim 2, wherein the neuronal damage in the brain is due to Alzheimer’s Disease, Parkinson’s Disease, AIDS-related dementia, senile dementia, stroke, trauma, cortical-basal ganglionic syndromes, progressive dementia, familial dementia with spastic paraparesis, progressive supranuclear palsy, multiple sclerosis, hepatic encephalopathy, Pick’s Disease, Huntington’s Disease, diffuse cerebral sclerosis of Schilder, or acute necrotizing hemorrhagic encephalomyelitis.
4. The method of claim 2, wherein the neuronal damage in the brain or spinal cord is a tumor or cancer.
5. The method of claim 1, wherein the IGF structural analog is des(1-3)IGF-I.
6. The method of claim 1, wherein the IGF structural analog is Arg3IGF-I, Leu24IGF-I, Leu60IGF-I, Long R3IGF-I, des(1-6)IGF-II, Gly1IGF-II, Arg6IGF-II or Leu27IGF-II.
7. The method of claim 1, wherein the mutant IGF or IGF analog is administered in an amount from about 0.01 \u03bcgkgday up to about 4 mgkgday.
8. The method of claim 1, wherein the IGF structural analog is administered by nonintracranial and nonintravertebral column administration.
9. A method of treating the central nervous system, comprising nonintracranial and nonintravertebral column administration of an effective amount of an IGF structural analog to treat or prevent neuronal damage in the central nervous system.
10. The method of claim 9, in which the damage is due to a disorder or disease in the central nervous system, except where the disease is amyotrophic lateral sclerosis.
11. The method of claim 9, wherein the damage is due to a tumor or cancer.
12. The method of claims 9, wherein the mutant IGF or IGF analog is des(1-3)IGF-I.
13. The method of claim 9, wherein the IGF structural analog is Arg3IGF-I, Leu24IGF-I, Leu60IGF-I, Long R3IGF-I, des(1-6)IGF-II, Gly1IGF-II, Arg6IGF-II or Leu27IGF-II.
14. The method of claim 9, wherein the mutant IGF or IGF analog is administered in an amount from about 0.01 \u03bcgkgday up to about 4 mgkgday.
15. The method of claim 9, wherein the nonintracranial and nonintravertebral column administration is percutaneous, subcutaneous, intramuscular, intravenous, intraarterial, by inhalation, or intranasal.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A method in a wireless communication system of notifying a calling party when a called party acknowledges a missed called notification, where said calling party initiated said missed call to said called party, said method comprising:
sending a notification to said calling party, on said called party viewing and acknowledging said missed call notification for said missed call from said calling party.
2. The method, as claimed in claim 1, wherein said calling party is subscribed to a notification service which regulates permission of calling parties to use said method.
3. The method, as claimed in claim 1, wherein said called party is subscribed to a notification service which regulates permission of called parties to use said method.
4. The method, as claimed in claim 1, wherein an application present on a communication device of said called party prompts said called party to send a notification.
5. The method, as claimed in claim 1, wherein an application present on a communication device of said called party sends said notification automatically.
6. The method, as claimed in claim 1, wherein an application present on a communication device of said called party sends said notification on receiving a confirmation from said called party.
7. The method, as claimed in claim 1, wherein said notification is one of:
a Short Messaging Service (SMS);
a Multimedia Messaging Service (MMS); and
a Wireless Application Protocol (WAP) message.
8. The method, as claimed in claim 1, wherein said notification is pre-defined by an application present on a communication device of said called party.
9. The method, as claimed in claim 1, wherein said notification is defined by said called party.
10. The method, as claimed in claim 1, wherein said notification is sent to said calling party via an application server.
11. The method, as claimed in claim 1, wherein an application server verifies if said calling party is subscribed to a notification service which regulates permission of calling parties to use said method.
12. The method, as claimed in claim 1, wherein said notification is sent to said calling party through networks of said calling party and said called party directly.
13. A communication device, said device comprising:
a prompt that, in response to the device receiving a missed call from a calling party and a user of the device accessing a record of said missed call, prompts the user of said communication device to send a notification to said calling party; and
a sending part operative to send said notification to said calling party.
14. The communication device as claimed in claim 13, wherein said communication device is adapted to send said notification in the form of one of:
a Short Messaging Service (SMS);
a Multimedia Messaging Service (MMS); and
a Wireless Application Protocol (WAP) message.
15. A method in a wireless communication system of notifying a calling party when a called party acknowledges a missed called, said method comprising:
detecting if a call initiated from the calling party to the called party is missed by the called party;
updating a list of missed calls on a device of the called party, wherein said updating includes adding a missed call record to the list indicating a missed called from the calling party in response to detecting said missed called;
detecting if at least one of the missed called list or the missed call record is accessed; and
generating a notification intended for said calling party in response to detecting said access.
16. The method of claim 15, wherein the call initiated from the calling party to the called party is detected as missed if any one of the following occurs: the called party does not answer the call, the calling party is returned a busy signal, the device of the called party is switched off or the device of the called party is outside a coverage area in which service is provided to the device.
17. The method of claim 15, wherein the notification includes an indication of a time of the detected access which resulted in the notification being generated.
18. The method of claim 15, wherein the notification includes an indication of a time that the missed call record was added to the list of missed calls.
19. The method of claim 15, further comprising:
sending the notification directed to the calling party.
20. The method of claim 15, further comprising:
providing a prompt to confirm sending of the notification;
sending said notification directed to the calling party in response to detecting an affirmative response to said prompt; and
not sending said notification directed to the calling party in response to detecting a negative response to said prompt.