1. A method of treating a condition associated with an abnormal calcitriol level in serum of a mammal, comprising:
administering a carbohydrate-boron complex to the mammal at a dosage and schedule that transiently increases endogenous blood calcitriol and that simultaneously maintains endogenous blood calcidiol concentration in the mammal; wherein the carbohydrate-boron complex is a fructoborate complex
wherein the condition is an inflammatory condition or overreaction of the immune system; and
wherein the dosage and schedule are effective to transiently increase the endogenous blood calcitriol in an amount of at least 20% over baseline.
2. The method of claim 1 wherein the abnormal calcitriol level is an abnormally low level.
3. The method of claim 1 wherein the inflammatory condition is an inflammatory reaction.
4. The method of claim 1 wherein the overreaction of the immune system is an autoimmune disease or an allergic reaction.
5. The method of claim 1 wherein the fructoborate complex is a calcium fructoborate.
6. The method of claim 1 wherein the dosage is at least 250 mg per day.
7. The method of claim 1 wherein the dosage is at least 500 mg per day.
8. The method of claim 1 wherein the dosage is between 200 mg and 1,000 mg per day.
9. The method of claim 1 wherein the dosage and schedule are effective to transiently increase the endogenous blood calcitriol in an amount of at least 50% over baseline.
10. The method of claim 1 wherein the dosage and schedule are effective to concurrently increase endogenous testosterone in an amount of at least 15% over baseline.
11. The method of claim 10 wherein the dosage is between 100 and 600 mg and the schedule comprises administration over at least 14 days.
12. In a method of providing a carbohydrate-boron complex to a mammal, the improvement comprising:
administering the carbohydrate-boron complex to the mammal after the mammal is found to have an inflammatory condition or overreaction of the immune system;
wherein the step of administering comprises administration of the carbohydrate-boron complex at a dosage and schedule that transiently increases endogenous blood calcitriol and that simultaneously maintains endogenous blood calcidiol concentration in the mammal; wherein the carbohydrate-boron complex is a fructoborate complex and
wherein the dosage and schedule are effective to transiently increase the endogenous blood calcitriol in an amount of at least 20% over baseline.
13. The method of claim 12 wherein the dosage and schedule are effective to also concurrently increase endogenous testosterone in an amount of at least 15% over baseline.
14. The method of claim 13 wherein the dosage is between 100 and 600 mg and the schedule comprises administration over at least 14 days.
15. The method of claim 12 wherein the dosage is at least 500 mg per day.
16. The method of claim 12 wherein the inflammatory condition is an inflammatory reaction, or wherein the overreaction of the immune system is an autoimmune disease or an allergic reaction.
17. The method of claim 12 wherein the endogenous blood calcitriol is abnormally low.
18. The method of claim 12 wherein the carbohydrate-boron complex is a calcium fructoborate.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A disposable pull-on diaper, comprising:
a front waist region, a rear waist region, and a crotch region extending in a longitudinal direction of said diaper between said front and rear waist regions;
transversely opposite lateral edge portions of said front and rear waist regions being permanently joined together in joining zones so as to form a waist-hole and a pair of leg-holes;
a pair of tape fasteners attached to an outer surface of one of said front and rear waist regions; and
each of said tape fasteners being elongated in a transverse direction of said diaper and having:
opposite proximal and distal end portions, said proximal end portion being directly secured to said one of said front and rear waist regions while said distal end portion overlaying the respective lateral edge portion of said one of said front and rear waist regions and being directly releasably attached to said one of said front and rear waist regions in at least one of the joining zones so as to serve as a finger-grip, and
an intermediate portion formed between and connecting said proximal end portion and said distal end portion and adapted to be releasably anchored on the other of said front and rear waist regions;
wherein said joining zones comprise a plurality of depressions in which the respective lateral edge portions of said front and rear waist regions are compressed and permanently joined together,
wherein the distal end portion of each of said tape fasteners and the respective lateral edge portions of said front and rear waist regions are all compressed together in at least one of said depressions, and wherein, in said at least one depression, said distal end portion is also directly releasably welded to the respective lateral edge portion of said one of said front and rear waist regions.
2. A disposable pull-on diaper, comprising:
a front waist region, a rear waist region, and a crotch region extending in a longitudinal direction of said diaper between said front and rear waist regions;
transversely opposite lateral edge portions of said front and rear waist regions being permanently joined together in joining zones so as to form a waist-hole and a pair of leg-holes;
a pair of tape fasteners attached to an outer surface of one of said front and rear waist regions; and
each of said tape fasteners being elongated in a transverse direction of said diaper and having:
opposite proximal and distal end portions, said proximal end portion being directly secured to said one of said front and rear waist regions while said distal end portion overlaying the respective lateral edge portion of said one of said front and rear waist regions and being directly releasably attached to said one of said front and rear waist regions in at least one of the joining zones so as to serve as a finger-grip, and
an intermediate portion formed between and connecting said proximal end portion and said distal end portion and adapted to be releasably anchored on the other of said front and rear waist regions;
wherein said joining zones comprise a plurality of depressions in which the respective lateral edge portions of said front and rear waist regions are compressed together,
wherein the distal end portion of each of said tape fasteners and the respective lateral edge portions of said front and rear waist regions are all compressed together in at least one of said depressions, and wherein, in said at least one depression, the distal end portion is also directly, releasably and mechanically engaged with a material forming the respective lateral edge portion of said one of said front and rear waist regions.
3. The diaper according to claim 1, wherein, in each of said tape fasteners, the proximal end portion directly secured to the outer surface of said one of said front and rear waist regions is spaced inwardly in the transverse direction from the respective distal end portion, which is directly releasably attached to said one of said front and rear waist regions in said at least one depression.
4. The diaper according to claim 1, wherein, in each of said tape fasteners, the proximal end portion is directly secured by adhesive to the outer surface of said one of said front and rear waist regions and is spaced inwardly in the transverse direction from the respective distal end portion, which is directly releasably attached to said one of said front and rear waist regions in said at least one of the depressions.
5. The diaper according to claim 2, wherein
in each of said tape fasteners, the proximal end portion is directly secured by adhesive to the outer surface of said one of said front and rear waist regions and is spaced inwardly in the transverse direction from the respective distal end portion, which is directly releasably attached to said one of said front and rear waist regions in said at least one of the depressions, and
in said at least one of said depressions, thermoplastic synthetic fibers contained in the respective lateral edge portions of said front and rear waist regions are inseparably mechanically entangled together and releasably joined to the distal end portion of the respective one of said tape fasteners.
6. The diaper according to claim 4, wherein, in said at least one of said depressions, thermoplastic synthetic resins contained in the respective lateral edge portions of said front and rear waist regions are inseparably welded together and are releasably welded to the distal end portion of the respective one of said tape fasteners.
7. The diaper according to claim 6, wherein the thermoplastic synthetic resins contained in the respective lateral edge portions of said front and rear waist regions have a softening point or a melting point lower than that of a thermoplastic synthetic resin contained in the distal end portion of the respective tape fastener, thereby allowing the thermoplastic synthetic resins in the respective lateral edge portions in said at least one of said depressions to be inseparably welded together and releasably welded to the thermoplastic synthetic resin in the distal end portion of the respective tape fastener.
8. The diaper according to claim 6, wherein
the thermoplastic synthetic resins contained in the respective lateral edge portions of said front and rear waist regions have a softening point or a melting point approximate to that of a thermoplastic synthetic material contained in the distal end portion of the respective tape fastener; and
the thermoplastic synthetic resins contained in the respective lateral edge portions have a thickness less than that of the thermoplastic synthetic material contained in the distal end portion of the respective tape fastener, thereby allowing the thermoplastic synthetic resins in the respective lateral edge portions in said at least one of said depressions to be inseparably welded together and releasably welded to the thermoplastic synthetic material in the distal end portion of the respective tape fastener.
9. The diaper according to claim 8, wherein the thickness of said thermoplastic synthetic material contained in the distal end of each said tape fastener is at least three times greater than the thickness of said thermoplastic synthetic resins contained in the respective lateral edge portions of said front and rear waist regions.
10. The diaper according to claim 6, wherein said at least one of said depressions includes
melted and solidified said thermoplastic synthetic resins contained in the respective lateral edge portions of said front and rear waist regions; and
a thermoplastic synthetic resin contained in the distal end portion of the respective tape fastener and releasably heat-bonded to said melted and solidified thermoplastic synthetic resins in the respective lateral edge portions.
11. The diaper according to claim 1, wherein each said fastener is in a folded state and comprises
a first tape section, and
a second tape section which is sandwiched, in said folded state of the fastener, between the first tape section and the outer surface of said one of said front and rear waist regions;
wherein
the first tape section comprises
the respective distal end portion which is, in said folded state of the fastener, directly releasably welded to the respective lateral edge portion of said one of said front and rear waist regions in said at least one depression, and
a first inner end portion which is, in said folded state of the fastener,
inwardly spaced in the transverse direction from said distal end portion; the second tape section comprises
the respective proximal end portion directly secured to the outer surface of said one of said front and rear waist regions at a location that is, in said folded state of the fastener, inwardly spaced in the transverse direction from said distal end portion, and
a second inner end portion which is bonded to the first inner end portion and, in said folded state of the fastener, inwardly spaced in the transverse direction from said proximal end portion.
12. The diaper according to claim 11, wherein each said fastener further comprises a fastening element adapted to be releasably anchored on the other of said front and rear waist regions;
wherein said fastening element is disposed on a underside of said first tape section and is, in said folded state of the fastener, located between the first and second tape sections to releasably attach the first tape section to the underlying second tape section.