Author: claimsbot

1. An engine system comprising:
a) an intake system through which charge air enters combustion chambers to support combustion of fuel for running the engine;
b) an exhaust system, including one or more exhaust gas treatment devices, through which products of combustion pass from the combustion chambers to the surrounding atmosphere;
c) a turbocharger having a turbine disposed in the exhaust system and a compressor disposed in the intake system;
d) a throttle valve disposed in the exhaust system downstream of both the one or more exhaust gas treatment devices and the turbine for controlling engine back-pressure;
e) an EGR flow path for recirculating exhaust gas from the exhaust system to the intake system, including an EGR valve for controlling flow through the EGR flow path, wherein the EGR flow path has a pierce point to the exhaust system upstream of the throttle valve and downstream of both the one or more exhaust gas treatment devices and the turbine; and
f) wherein EGR flow path has a pierce point to the intake system upstream of the compressor.
2. An engine system as set forth in claim 1 in which the exhaust system further comprises a muffler, and the throttle valve is disposed upstream of the muffler in the exhaust system.
3. An engine system as set forth in claim 1 in which one of the one or more exhaust gas treatment devices comprises a catalyzed diesel particulate filter.
4. An engine system as set forth in claim 1 further including an EGR cooler disposed in the EGR flow path between the EGR valve and the pierce point to the intake system.
5. An engine system as set forth in claim 1 in which the throttle valve and the EGR valve are embodied in a device assembled as a unit into the exhaust system downstream of both the one or more exhaust gas treatment devices and the turbine and upstream of a muffler of the exhaust system.
6. An engine system as set forth in claim 1 in which the throttle valve and the EGR valve are under control of an engine control system via respective actuators for selectively restricting the respective valves to attain desired EGR flow through the EGR flow path.
7. A motor vehicle comprising:
a) an internal combustion engine for propelling the vehicle, including an intake system through which charge air enters combustion chambers to support combustion of fuel for running the engine and an exhaust system, including one or more exhaust gas treatment devices, through which products of combustion pass from the combustion chambers to the surrounding atmosphere;
b) a turbocharger having a turbine disposed in the exhaust system and a compressor disposed in the intake system;
c) a throttle valve disposed in the exhaust system downstream of both the one or more exhaust gas treatment devices and the turbine for controlling engine back-pressure; and
c) an EGR flow path for recirculating exhaust gas from the exhaust system to the intake system, including an EGR valve for controlling flow through the EGR flow path, wherein the EGR flow path has a pierce point to the exhaust system upstream of the throttle valve and downstream of both the one or more exhaust gas treatment devices and the turbine, and a pierce point to the intake system that is upstream of the compressor.
8. A motor vehicle as set forth in claim 7 in which the exhaust system further comprises a muffler, and the throttle valve is disposed upstream of the muffler in the exhaust system.
9. A motor vehicle as set forth in claim 7 in which one of the one or more exhaust gas treatment devices comprises a catalyzed diesel particulate filter.
10. A motor vehicle as set forth in claim 7 further including an EGR cooler disposed in the EGR flow path between the EGR valve and the pierce point to the intake system.
11. A motor vehicle as set forth in claim 7 in which the throttle valve and the EGR valve are embodied in a device assembled as a unit into the exhaust system downstream of both the one or more exhaust gas treatment devices and the turbine and upstream of a muffler of the exhaust system.
12. A motor vehicle as set forth in claim 7 in which the throttle valve and the EGR valve are under control of an engine control system via respective actuators for selectively restricting the respective valves to attain desired EGR flow through the EGR flow path.
13. A motor vehicle as set forth in claim 7 in which the vehicle has an engine compartment at the front of the vehicle and an undercarriage extending rearward from the engine compartment, the engine is disposed in the engine compartment, and the throttle valve is placed in the undercarriage outside and rearward of the engine compartment.
14. A motor vehicle as set forth in claim 13 in which the throttle valve and the EGR valve are embodied in a device assembled into the vehicle as a unit placed in the undercarriage outside and rearward of the engine compartment.
15. A method for low-pressure EGR control in a motor vehicle internal combustion engine having a turbocharger, the method comprising:
a) controlling engine back-pressure by selectively restricting a throttle valve disposed in an exhaust system of the engine downstream of both one or more exhaust gas treatment devices in the exhaust system and a turbine of the turbocharger in the exhaust system;
b) controlling, in conjunction with control of engine back-pressure, EGR flow to an intake system of the engine through an EGR flow path having a pierce point to the exhaust system upstream of the throttle valve and downstream of both the one or more exhaust gas treatment devices and the turbine and a pierce point to the intake system upstream of a compressor of the turbocharger in the intake system by selectively restricting an EGR valve in the EGR flow path to achieve desired EGR flow.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

What is claimed is:

1. A purified and isolated 528 kD molecular weight protein, free of the cell line M20 and M20-2, said protein being characterized by a pI of 4.1 and by having general cytostatic but not cytotoxic activity.
2. A purified and isolated 524 kD molecular weight protein, free of the cell line M20 and M20-2, said protein being characterized by a pI of 4.1 and by having general cytostatic but not cytotoxic activity.
3. A protein of claim 1 or claim 2, wherein the cytostatic activity is on immune cells.
4. A purified and isolated 528 kD molecular weight protein, free of the cell line M20-2, said protein being characterized by a pI of 4.1 and the inhibition or reduction of an inflammatory response.
5. A purified and isolated 524 kD molecular weight protein, free of the cell line M20-2, said protein being characterized by a pI of 4.1 and the inhibition or reduction of an inflammatory response.
6. A purified and isolated 528 kD molecular weight protein, free of the cell line M20-2, said protein being characterized by a pI of 4.1 and the inhibition or reduction of IL-1 associated effects.
7. A purified and isolated 524 kD molecular weight protein, free of the cell line M20-2, said protein being characterized by a pI of 4.1 and the inhibition or reduction of IL-1 associated effects.
8. A protein of claim 6 or claim 7, wherein one of the IL-1 associated effects is an inflammatory response.
9. A therapeutic composition comprising an anti-inflammatory-effective amount of the protein of claim 1 in combination with a pharmaceutically acceptable carrier.
10. A method of inhibition or reduction of an inflammatory response which comprises administering to an individual in need of such treatment an effective amount of the protein of claim 1.
11. The method of claim 10 wherein the amount is about 0.0001-1.0 g per kg of body weight.
12. A substantially pure protein free of major contaminants as shown by the presence of one band in SDS-PAGE, the protein having general cytostatic but not cytotoxic activity and the same amino acid sequence and isoelectric point as the cytostatic factor protein with an isoelectric point of 4.10.2 obtained from M20-2 cells, and active fragments thereof.
13. A protein of claim 12, wherein the molecular weight is 548.
14. A protein of claim 12, wherein the molecular weight is 544.

1. A Global Positioning System (GPS)-based positioning system, comprising:
a GPS terminal, including:
a GPS section for receiving and processing a GPS signal;
a call processing section, coupled to the GPS section via an interface, a first message being passed from the call processing section to the GPS section via the interface, and a second message is passed via the interface from the GPS section to the call processing section in response thereto, wherein the first message is a Quality of Service (QOS) message and the second message is a QoS response message;

a location aiding server, and
a communication system, coupled to the GPS section and the call processing section, for selectively transmitting first data to the GPS terminal from the location aiding server and receiving data from the GPS terminal to be sent to the location aiding server, based on the first message and the second message.
2. The system of claim 1, wherein the location aiding server calculates a position of the GPS terminal based upon data received from the GPS terminal.
3. The system of claim 2, wherein the GPS section further comprises a processor separate from the call processor.
4. The system of claim 3, wherein the call processor uses a predetermined strategy to determine content of the second message.
5. The system of claim 4, wherein the predetermined strategy employed by the call processor of the GPS section is determined by at least one parameter selected from a group comprising: a signal level of received satellite signals, a number of satellites from which signals are being received, a frequency range used for searching for satellites, a time range used for searching for satellites, and a current searching status of the GPS section.
6. The system of claim 5, wherein the second message comprises a message indicating that a QoS request can be met by the GPS section.
7. The system of claim 5, wherein the second message comprises a message indicating that a QoS request can not be obtained by the GPS section and can be obtained if additional time is granted by the call processor.
8. The system of claim 7, wherein the call processor switches an operational mode of the GPS section in response to the second message.
9. The system of claim 7, wherein the GPS section switches an operational mode of the GPS section based on content of the second message.
10. The system of claim 5, wherein the second message comprises a message indicating that a QoS request cannot be obtained by the GPS section.
11. The system of claim 10, wherein the call processor switches an operational mode of the GPS section in response to the second message.
12. The system of claim 10, wherein the GPS section switches an operational mode of the GPS section based on content of the second message.
13. The system of claim 10, wherein the location aiding server sends aiding data to the GPS section.
14. The system of claim 7, wherein the location aiding server sends aiding data to the GPS section.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method for synchronizing multiple media streams, the method comprising:
querying a plurality of media stream output devices;
responsive to the querying step, receiving, from each queried media stream output device: a) its current time according to its device clock, b) a next available media stream output time, according to its device clock and c) a delta between available media stream output times;
determining an earliest available media stream output time common to each media stream output device based on data received responsive to the querying step; and
synchronizing output of the plurality of media streams by providing each media stream to an associated media stream output device at the earliest available common media stream output time.
2. The method of claim 1 further comprising:
defining one media stream of the plurality as a master media stream;
slaving at least one additional media stream of the plurality off the master media stream.
3. The method of claim 1 wherein:
the plurality of media streams comprises at least a video stream and an audio stream.
4. The method of claim 1 wherein:
at least one of the plurality of media streams comprises a media stream from a group of media streams consisting of:
a video stream;
an audio stream;
a closed captioning data stream;
a stream of MIDI events;
a stream of text to Braille data; and
a stream of side band data.
5. The method of claim 1 further comprising:
correlating each received device clock time into a common host clock time; and
referencing events on the plurality of media stream output devices in the common host clock time.
6. A computer readable medium containing a computer program product for synchronizing multiple media streams, the computer program product comprising:
program code for querying a plurality of media stream output devices;
program code for receiving, from each queried media stream output device: a) its current time according to its device clock, b) a next available media stream output time, according to its device clock and c) a delta between available media stream output times;
program code for determining an earliest available media stream output time common to each media stream output device based on data received responsive to the querying step; and
program code for synchronizing output of the plurality of media streams by providing each media stream to an associated media stream output device at the earliest available common media stream output time.
7. The computer program product of claim 6 further comprising:
program code for defining one media stream of the plurality as a master media stream;
program code for slaving at least one additional media stream of the plurality off the master media stream.
8. The computer program product of claim 6 wherein:
the plurality of media streams comprises at least a video stream and an audio stream.
9. The computer program product of claim 6 wherein:
at least one of the plurality of media streams comprises a media stream from a group of media streams consisting of:
a video stream;
an audio stream;
a closed captioning data stream;
a stream of MIDI events;
a stream of text to Braille data; and
a stream of side band data.
10. The computer program product of claim 6 further comprising:
program code for correlating each received device clock time into a common host clock time; and
program code for referencing events on the plurality of media stream output devices in the common host clock time.
11. A computer system for synchronizing multiple media streams, the computer system comprising:
a processor;
a software portion configured to query a plurality of media stream output devices;
a software portion configured to receive, from each queried media stream output device: a) its current time according to its device clock, b) a next available media stream output time, according to its device clock and c) a delta between available media stream output times;
a software portion configured to determine an earliest available media stream output time common to each media stream output device based on data received responsive to querying step; and
a software portion configured to synchronize output of the plurality of media streams by providing each media stream to an associated media stream output device at the earliest available common media stream output time.
12. The computer system of claim 11 further comprising:
a software portion configured to define one media stream of the plurality as a master media stream;
a software portion configured to slave at least one additional media stream of the plurality off the master media stream.
13. The computer system of claim 11 wherein:
the plurality of media streams comprises at least a video stream and an audio stream.
14. The computer system of claim 11 wherein:
at least one of the plurality of media streams comprises a media stream from a group of media streams consisting of:
a video stream;
an audio stream;
a closed captioning data stream;
a stream of MIDI events;
a stream of text to Braille data; and
a stream of side band data.
15. The computer system of claim 11 further comprising:
a software portion configured to correlate each received device clock time into a common host clock time; and
a software portion configured to reference events on the plurality of media stream output devices in the common host clock time.
16. A computer system for synchronizing multiple media streams, the computer system comprising:
a processor;
means for querying a plurality of media stream output devices;
means for receiving, from each queried media stream output device: a) its current time according to its device clock, b) a next available media stream output time, according to its device clock and c) a delta between available media stream output times;
means for determining an earliest available media stream output time common to each media stream output device based on data received responsive to querying step; and
means for synchronizing output of the plurality of media streams by providing each media stream to an associated media stream output device at the earliest available common media stream output time.
17. The computer system of claim 16 further comprising:
means for defining one media stream of the plurality as a master media stream;
means for slaving at least one additional media stream of the plurality off the master media stream.
18. The computer system of claim 16 wherein:
the plurality of media streams comprises at least a video stream and an audio stream.
19. The computer system of claim 16 wherein:
at least one of the plurality of media streams comprises a media stream from a group of media streams consisting of:
a video stream;
an audio stream;
a closed captioning data stream;
a stream of MIDI events;
a stream of text to Braille data; and
a stream of side band data.
20. The computer system of claim 16 further comprising:
means for correlating each received device clock time into a common host clock time; and
means for referencing events on the plurality of media stream output devices in the common host clock time.