Author: claimsbot

1. A method of treating either CD33+ acute myeloid leukemia or CD33+ chronic myeloid leukemia by administering a pharmaceutically effective amount of compound 3-O-p-coumaryl quinic acid to a subject in need thereof.
2. A method as claimed in claim 1, wherein the compound has 100% activity against CD33+ chronic myeloid leukemia.
3. A method as claimed in claim 1, wherein the compound has 85% activity against CD33+ chronic myeloid leukemia.
4. A method as claimed in claim 1, wherein the subject is an animal.
5. A method as claimed in claim 1, wherein the subject is a human being.
6. A method as claimed in claim 1, wherein the administering is intravenous.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. In a network where a virtual local area network is set up, a method for detecting topology of nodes constituting said virtual local area network, the method for detecting virtual local area network topology comprising:
a step in which an arbitrary node that indisputably belongs to said virtual local area network sends a request packet including a count value indicating the number of communication hops across nodes to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
a step in which, upon receiving said request packet, each of said adjacent nodes sends said request packet in which said count value is incremented or decremented, as predetermined, to each of its adjacent nodes that belong to said virtual local area network and are adjacent to the node, excluding a sender of said request packet received, and sends a reply packet including said sender’s address, an address of the node that is a replying node, and said count value to a given return destination;
an analysis step in which said given return destination collects said reply packets sent thereto and detects topology of said nodes constituting said virtual local area network from information contained in said reply packets.
2. The method for detecting virtual local area network topology according to claim 1, wherein:
said analysis step comprises the steps of:
creating a table of records comprising said count value entries, said sender address entries, and said replying node address entries from said collected packets;
sorting the records in said table by said count value entries as a first key and by said sender address entries as a second key;
linking said sender node and said replying node in each record and plotting sender nodes with the same sender address as a convergence point, and
determining topology of said virtual local area network by analyzing the records in said table in order.
3. The method for detecting virtual local area network topology according to claim 1, wherein said count value is either Time To Live or hop count from the arbitrary node.
4. The method for detecting virtual local area network topology according to claim 1, wherein:
said request packet includes said sender address and the number of a sending port through which the request packet is sent;
said reply packet includes said sending port number as well as said sender address and the number of a receiving port through which said request packet was received as well as said replying node address; and
said analysis step includes a step of creating a table of records comprising said count value entries, said sender address entries, said sending port number entries, said replying node address entries, and said receiving port number entries from said collected packets.
5. The method for detecting virtual local area network topology according to claim 1, wherein:
the step of sending said request packet includes a step of including time at which said request packet is sent in said request packet;
the step of sending the reply packet to the given return destination includes a step of including time at which said request packet is received and time at which said reply packet is sent in said reply packet; and
said analysis step includes a step of recording time at which said reply packet is received and a step of obtaining round trip time from the time at which said request packet is sent, the time at which said request packet is received, the time at which said reply packet is sent, and the time at which said reply packet is received.
6. In a network where a virtual local area network is set up, a method for detecting topology of nodes constituting said virtual local area network, the method for detecting virtual local area network topology comprising:
a step in which an arbitrary node that indisputably belongs to said virtual local area network sends a first request packet including a count value indicating the number of communication hops across nodes and an initial value of said count value to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
a step in which, upon receiving said request packet, each of said nodes sets its node address for a source address of said first request packet received, sends the packet as a first reply packet to a given return destination, and sends said first request packet in which said count value is incremented or decremented, as predetermined, to each of its adjacent nodes that belong to said virtual local area network and are adjacent to the node, excluding a sender of said first request packet received;
a step in which said given return destination collects said reply packets sent thereto and makes a list of nodes per hop count, based on said count values and said initial values included in said reply packets;
a sweep check step in which the arbitrary node sends, to a node to be checked, a second request packet in which the number of hops up to said node to be checked is set as said count value and said initial value and repeats sending the packet until said set number of hops becomes 1;
a step in which, upon receiving said second request packet, each of said nodes sets said initial value for said count value in said second request packet, sets its node address for a source address of said second request packet received, and sends the packet as a second reply packet to the given return destination; and
a step in which said given return destination assigns a node for said node to be checked from the nodes list in descending order in the hop counts and repeats said sweep check step until interconnections of all nodes in said nodes list are ascertained.
7. The method for detecting virtual local area network topology according to claim 6, wherein said given return destination is the arbitrary node.
8. The method for detecting virtual local area network topology according to claim 6, wherein said count value is Time To Live.
9. The method for detecting virtual local area network topology according to claim 6, wherein said virtual local area network consists of a plurality of lower virtual local area networks.
10. In a network where a virtual local area network is set up, a method for detecting topology of nodes constituting said virtual local area network, the method for detecting virtual local area network topology in which:
an arbitrary node that indisputably belongs to said virtual local area network executes the steps of:
sending a request packet including a count value indicating the number of communication hops across nodes to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
receiving and collecting reply packets sent from the nodes that belong to said virtual local area network;
extracting said count values incremented or decremented, as predetermined, upon each transit through a node up to each of said nodes, the addresses of said nodes, and the addresses of said request packet sending nodes to said nodes from said reply packets received and collected; and
detecting topology of said nodes constituting said virtual local area network from information extracted from said reply packets.
11. The method for detecting virtual local area network topology according to claim 10, wherein said extracting step includes a step of creating a table of records comprising said count value entries, said sender address entries, and said replying node address entries from said collected packets.
12. In a network where a virtual local area network is set up, a node apparatus comprising:
means in which each of nodes constituting said virtual local area network receives a request packet including a count value indicating the number of communication hops across nodes, hop-by-hop sent in a multicast domain of said virtual local area network from an arbitrary node that indisputably belongs to said virtual local area network; and
means in which, upon receiving said request packet, each of said nodes sends said request packet in which said count value is incremented or decremented, as predetermined, to each of its adjacent nodes that belong to said virtual local area network and are adjacent to the node, excluding a sender of said request packet received, and sends back a reply packet including said sender’s address, an address of the node that is a replying node, and said count value to said arbitrary node.
13. The node apparatus according to claim 12, further comprising:
analysis means for collecting said reply packets and detecting the topology of the nodes constituting said virtual local area network from information contained in the reply packets.
14. A recording medium having a computer-executable program recorded thereon, said program comprising instructions for a process which detects, in a network where a virtual local area network is set up, topology of nodes constituting said virtual local area network, said process comprising:
a step in which an arbitrary node that indisputably belongs to said virtual local area network sends a request packet including a count value indicating the number of communication hops across nodes to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
a step in which, upon receiving said request packet, each of said adjacent nodes sends said request packet in which said count value is incremented or decremented, as predetermined, to each of its adjacent nodes that belong to said virtual local area network and are adjacent to the node, excluding a sender of said request packet received, and sends a reply packet including said sender’s address, an address of the node that is a replying node, and said count value to a given return destination;
an analysis step in which said given return destination collects said reply packets sent thereto and detects topology of said nodes constituting said virtual local area network from information contained in said reply packets.
15. A recording medium having a computer-executable program recorded thereon, said program comprising instructions for a process which detects, in a network where a virtual local area network is set up, topology of nodes constituting said virtual local area network, said process comprising:
a step in which an arbitrary node that indisputably belongs to said virtual local area network sends a first request packet including a count value indicating the number of communication hops across nodes and an initial value of said count to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
a step in which, upon receiving said request packet, each of said nodes sets its node address for a source address of said first request packet received, sends the packet as a first reply packet to a given return destination, and sends said first request packet in which said count value is incremented or decremented, as predetermined, to each of its adjacent nodes that belong to said virtual local area network and are adjacent to the node, excluding a sender of said first request packet received;
a step in which said given return destination collects said reply packets sent thereto and makes a list of nodes per hop count, based on said count values and said initial values included in said reply packets;
a sweep check step in which an arbitrary node sends, to a node to be checked, a second request packet in which the number of hops up to said node to be checked is set as said count value and said initial value and repeats sending the packet until said set number of hops becomes 1;
a step in which, upon receiving said second request packet, each of said nodes sets said initial value for said count value in said second request packet, sets its node address for a source address of said second request packet received, and sends the packet as a second reply packet to the given return destination; and
a step in which said given return destination assigns a node for said node to be checked from the nodes list in descending order in the hop counts and repeats said sweep check step until interconnections of all nodes in said nodes list are ascertained.
16. A recording medium having a computer-executable program recorded thereon, said program comprising instructions for a process which detects, in a network where a virtual local area network is set up, topology of nodes constituting said virtual local area network, said process comprising:
a step in which an arbitrary node that indisputably belongs to said virtual local area network sends a request packet including a count value indicating the number of communication hops across nodes to each of its adjacent nodes that belong to said virtual local area network and are adjacent;
a step in which said arbitrary node receives and collects reply packets sent from the nodes that belong to said virtual local area network;
a step in which said arbitrary node extracts said count values incremented or decremented, as predetermined, upon each transit through a node up to each of said nodes, the addresses of said nodes, and the addresses of said request packet sending nodes to said nodes from said reply packets received and collected; and
a step in which said arbitrary node detects the topology of said nodes constituting said virtual local area network from information extracted from said reply packets.

1. An aspiration catheter for removing particles from a blood vessel, the catheter comprising:
an elongate aspiration tube having an aspiration lumen defined by an inner surface of the aspiration tube, the aspiration tube having a proximal end port and a distal end port fluidly connected via the aspiration lumen; and
a guidewire tube disposed alongside and not extending proximally beyond a distal portion of the aspiration tube, the guidewire tube having a guidewire lumen defined by an inner surface of the guidewire tube and having a proximal end opening and a distal end opening that are connected via the guidewire lumen,
wherein the guidewire tube includes a distal portion secured to the distal portion of the aspiration tube and a proximal portion defining a detachable strain relief segment that is minimally attached to the distal portion of the aspiration tube, such that a transverse force applied to the guidewire tube detaches only the strain relief segment from the aspiration tube.
2-5. (canceled)
6. The aspiration catheter of claim 1, wherein the guidewire tube is secured to the aspiration tube by an over sleeve that surrounds the guidewire tube and the aspiration tube, the over sleeve having a proximal portion of a first thickness that overlays the strain relief segment and a distal portion of a second thickness that overlays the distal portion of the guidewire tube, the second thickness being greater than the first thickness.
7. The aspiration catheter of claim 1, wherein the guidewire tube is made from PTFE and the strain relief segment is minimally attached to the aspiration tube by a thermal bond, wherein the thermal bond is broken when the transverse force is applied thereto.
8. The aspiration catheter of claim 1, wherein the guidewire tube has a length of 10-30 cm.
9. The aspiration catheter of claim 1, wherein the length of the strain relief segment is 0.5-10% of the length of the guidewire tube.
10. The aspiration catheter of claim 1, wherein the distal portion of the guidewire tube is secured to the aspiration tube by a securement means selected from a group consisting of an adhesive, a solvent bond, thermal bonding, and an over sleeve that surrounds the distal portion of the guidewire tube and the aspiration tube.
11. The aspiration catheter of claim 1, wherein the aspiration tube further comprises:
a reinforcement layer encapsulated within a wall of the aspiration tube.
12. The aspiration catheter of claim 11, wherein the aspiration tube further comprises:
a liner having an inner surface defining the aspiration lumen; and
a jacket disposed about and adhered to the liner, wherein the reinforcement layer is interposed between the jacket and the liner.
13. The aspiration catheter of claim 11, wherein the reinforcement layer comprises a tubular braid.
14. The aspiration catheter of claim 1, wherein the distal port of the aspiration tube forms an oblique opening that faces away from the guidewire tube.
15. The aspiration catheter of claim 1, further comprising:
a fitting mounted to a proximal end of the aspiration tube in fluid communication with the proximal port.
16. A method of making an aspiration catheter, the method comprising the following steps:
providing an elongate, flexible first tube having a single lumen extending longitudinally therethrough;
providing a flexible second tube having a lumen extending longitudinally therethrough and being open at proximal and distal ends thereof, wherein the second tube is substantially shorter than the first tube; and
securing the second tube beside a distalmost portion of the first tube such that a proximal portion of the second tube that is of a length that is 0.5-10% of a total length of the second tube forms a detachable strain relief segment that is minimally attached to the distalmost portion of the first tube, such that a transverse force applied to the second tube detaches only the strain relief segment from the first tube.
17-18. (canceled)
19. The method of claim 16, wherein securing the second tube beside a distalmost portion of the first tube farther comprises surrounding the first and second tubes with an over sleeve, the over sleeve having a proximal portion of a first thickness that overlays the strain relief segment and a distal portion of a second thickness that overlays the remaining portion of the second tube beside the distalmost portion of the first tube, the second thickness being greater than the first thickness.
20. The method of claim 16, wherein the second tube is made from PTFE and the strain relief segment is minimally attached to the first tube by a thermal bond, wherein the thermal bond is broken when a transverse force is applied to urge the second tube away from the first tube.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A seat apparatus, comprising:
a seat cushion;
a seat back attached to, and inclinable relative to, the seat cushion and movable between an upright position and a forward inclined position;
a biasing member which biases the seat back in a forward inclined direction;
a lock mechanism configured to lock the seat back at the upright position;
a lock lever which is supported on the seat cushion and configured to switch the lock mechanism between a lock state and a lock release state, the lock lever moveable in a lock release direction to cause the lock mechanism to be in the lock release state, the lock lever moveable in a lock direction to cause the lock mechanism to be in the lock state when the seat back reaches the upright position;
a gear which is pivotally supported on the seat back, is configured to be turned in a first turning direction corresponding to the forward inclined direction and in a second turning direction, and has a first abutting portion and a second abutting portion, wherein the first abutting portion is set to abut on a stopper fixed in the seat cushion by turning of the gear in the first turning direction while the second abutting portion is set to abut on the lock lever by turning of the gear in the second turning direction thereby to move the lock lever in the lock release direction;
a motor which has a motor shaft meshed with the gear and is attached to the seat back, and is configured to cause the gear to be turned in the first turning direction by rotating the motor shaft in a first rotating direction and to cause the gear to be turned in the second turning direction by rotating the motor shaft in a second rotating direction;
a motor controlling unit configured to control driving of the motor;
a detecting unit configured to detect whether or not the seat back is in the upright position; and
a manipulating unit configured to be manipulated when the seat back is to be moved to either the upright position or the forward inclined position,
wherein, in a case where the manipulating unit is manipulated when the detecting unit detects that the seat back is in the upright position, the motor controlling unit is configured to control the driving of the motor to rotate the motor shaft in the second rotating direction until the gear turned in the second turning direction moves the lock lever in the lock release direction at the second abutting portion thereby to cause the lock mechanism to be in the lock release state, and
in a case where the manipulating unit is manipulated when the detecting unit detects that the seat back is not in the upright position, the motor controlling unit is configured to control the driving of the motor to rotate the motor shaft in the first rotating direction to move the seat back, after the first abutting portion has abutted on the stopper, until the detecting unit detects the fact that the seat back is in the upright position.
2. The seat apparatus according to claim 1, wherein
the detecting unit is in contact with a part of the seat back in the upright position, and this contact state is set to be released by inclination of the seat back from the upright position to the forward inclined position, and
the detecting unit is configured to detect whether or not the seat back is in the upright position based on the contact state.
3. A seat apparatus having a seat back which is attached to a seat cushion and moves between an upright position and a forward inclined position, comprising:
a gear pivotally supported on the seat back and including a first abutting portion which abuts on a stopper fixed to the seat cushion;
a motor attached to the seat back and having a motor shaft which is meshed with the gear; and
a motor controlling unit which controls the motor,
wherein the motor controlling unit rotates the motor shaft of the motor in a first direction according to an external input so as to press the first abutting portion of the gear against the stopper, and then moves the seat back to the upright position along with the motor.
4. The seat apparatus according to claim 3, further comprising:
a detecting unit which detects whether or not the seat back is in the upright position,
wherein the motor controlling unit rotates the motor shaft of the motor in the first direction until the detecting unit detects the fact that the seat back is in the upright position.
5. The seat apparatus according to claim 4, further comprising:
a lock mechanism which locks the seat back in the upright position when the seat back reaches the upright position.
6. The seat apparatus according to claim 5, further comprising:
a biasing member which biases the seat back in a forward inclined direction; and
a lock lever which releases the seat back locked by the lock mechanism,
wherein, when the seat back is in the upright position, the motor controlling unit releases, via the lock lever and according to the external input, the seat back locked by the lock mechanism.
7. The seat apparatus according to claim 6, wherein
the gear includes a second abutting portion which presses the lock lever,
the lock lever is set to release the seat back locked by the lock mechanism when the lock lever is pressed by the second abutting portion, and
the motor controlling unit rotates the motor shaft of the motor in a second direction so as to press the lock lever by the second abutting portion of the gear, and then releases the seat back locked by the lock mechanism.
8. The seat apparatus according to claim 7, wherein
the detecting unit includes a lever which is in contact with a part of the seat back in the upright position, and detects whether or not the seat back is in the upright position based on the contact state between the lever and the seat back.
9. A seat apparatus, comprising:
a seat cushion;
a seat back which is attached to the seat cushion and pivotable between an upright position and a forward inclined position;
a gear which is pivotally supported on the seat back to be rotatable about an axis, and includes a first abutting portion for abutting a stopper fixed to the seat cushion; and
a motor attached to the seat back and having a motor shaft which is meshed with the gear;
wherein, in response to a rotation of the motor shaft in a first direction,
the first abutting portion of the gear is pressed, by the rotation of the motor shaft, against the stopper, and
the seat back is moved, by the rotation of the motor shaft, to the upright position along with the motor while the gear is kept irrotational about the axis due to abutment between the first abutting portion and the stopper.
10. The seat apparatus according to claim 9, further comprising a motor controlling unit configured to control the motor.
11. The seat apparatus according to claim 10, further comprising:
a detecting unit configured to detect whether or not the seat back is in the upright position,
wherein the motor controlling unit is configured to control, according to an external input, the motor to rotate the motor shaft in the first direction until the detecting unit detects that the seat back is in the upright position.
12. The seat apparatus according to claim 11, further comprising:
a lock mechanism configured to lock the seat back in the upright position when the seat back reaches the upright position.
13. The seat apparatus according to claim 12, further comprising:
a biasing member biasing the seat back toward the forward inclined position; and
a lock lever configured to release the seat back locked by the lock mechanism,
wherein, when the seat back is in the upright position, the motor controlling unit is configured to release, via the lock lever and according to the external input, the seat back locked by the lock mechanism.
14. The seat apparatus according to claim 13, wherein
the gear includes a second abutting portion for pressing the lock lever,
the lock lever is configured to release the seat back locked by the lock mechanism when the lock lever is pressed by the second abutting portion, and
the motor controlling unit is configured to control the motor to rotate the motor shaft in a second direction opposite to the first direction so as to press the second abutting portion of the gear against the lock lever and to release the seat back locked by the lock mechanism.
15. The seat apparatus according to claim 14, wherein
the detecting unit includes a lever which is in contact with a part of the seat back in the upright position, and
the detecting unit is configured to detect whether or not the seat back is in the upright position based on a contact state between the lever and the part of the seat back.
16. The seat apparatus according to claim 9, wherein, in response to the rotation of the motor shaft in the first direction and when the seat back is at an intermediate position between the upright position and the forward inclined position,
during a first period, the gear is rotated, by the rotation of the motor shaft and while the seat back is irrotational relative to the seat cushion, until the first abutting portion of the gear is pressed against the stopper, and
during a second period subsequent to the first period, the seat back is moved, by the rotation of the motor shaft and while the gear is kept irrotational about the axis due to abutment between the first abutting portion and the stopper, to the upright position along with the motor.
17. The seat apparatus according to claim 16, wherein
during the first period, the gear is rotated in a first rotational direction, and
during the second period, the seat back is rotated in a second rotational direction opposite to the first rotational direction.