1. A compound having the following structural formula (I):
in which:
R1 is an \u2014OH radical, a radical OR7 or a radical \u2014NR8R9, wherein R7, R8 and R9 are as defined below;
R2 is a hydrogen atom, a fluorine atom, a chlorine atom, an alkyl radical having 1 to 3 carbon atoms, an \u2014OH radical or a radical \u2014OR10, wherein R10 is as defined below;
R3 is a hydrogen atom, a methyl radical, an ethyl radical, an isopropyl radical, a tert-butyl radical or a \u2014CF3 radical;
R4 is a hydrogen atom, a fluorine atom, a chlorine atom, a radical \u2014OR11, a methyl radical, an ethyl radical, an isopropyl radical, a tert-butyl radical or a \u2014CF3 radical, wherein R11 is as defined below;
R5 and R6, which may be identical or different, are each a hydrogen atom, a methyl radical, an ethyl radical, an n-propyl radical, an isopropyl radical, a tert-butyl radical, a radical \u2014COR12 or may together form, with the nitrogen atom from which they depend, a piperidine, pyrrolidine, morpholine, pyrrolidin-2-one or piperid-2-one heterocycle, which may be unsubstituted or substituted with one or more methyl, ethyl, fluorine or chlorine groups, wherein R12 is as defined below;
Q is an \u2014OH radical, a radical \u2014OR13, a radical \u2014NR14R15 or a radical \u2014SO2R16, wherein R13, R14, R15 and R16 are as defined below;
is a divalent radical having the following structure:
wherein R17 is as defined below;
R7 is a linear or branched alkyl radical having from 1 to 20 carbon atoms, an alkenyl radical, a monohydroxyalkyl radical, a polyhydroxyalkyl radical, an aryl radical, an optionally substituted aralkyl radical or a sugar residue;
R8 and R9, which may be identical or different, are each a hydrogen atom, an \u2014OH radical, an alkyl radical having 1 to 6 carbon atoms, a monohydroxyalkyl radical, a polyhydroxyalkyl radical, an optionally substituted aryl radical, or form with the nitrogen atom from which they depend, an amino acid residue or a peptide residue, or alternatively R8 and R9 may together form, a piperidine, pyrrolidine, morpholine, pyrrolidin-2-one or piperid-2-one heterocycle;
R10 is an alkyl radical having from 1 to 6 carbon atoms;
R11 is an alkyl radical having from 1 to 6 carbon atoms or a mono- or polyether radical;
R12 is an alkyl radical having from 1 to 6 carbon atoms or a radical \u2014OR18, wherein R18 is as defined below;
R13 is a linear or branched alkyl radical having from 1 to 15 carbon atoms;
R14 and R15, which may be identical or different, are each a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms or a radical \u2014COR19, wherein R19 is as defined below;
R16 is an alkyl radical having from 1 to 6 carbon atoms;
R17 is a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms or a \u2014CF3 radical;
R18 is an alkyl radical having from 1 to 6 carbon atoms;
R19 is an alkyl radical having from 1 to 6 carbon atoms; or salt thereof when R1 is an OH function, or isomer thereof.
2. An alkali or alkaline earth metal, or zinc or organic amine salt of a compound as defined by claim 1.
3. A compound as defined by claim 1, comprising at least one alkyl radical substituent having from 1 to 6 carbon atoms and selected from the group consisting of methyl, ethyl, n-propyl, i-propyl, cyclopropyl, isopropyl, n-butyl, i-butyl, t-butyl, n-pentyl and n-hexyl radicals.
4. A compound as defined by claim 1, comprising at least one alkyl radical substituent having from 1 to 15 carbon atoms and selected from the group consisting of methyl, ethyl, propyl, isopropyl, cyclopropyl, n-butyl, i-butyl, t-butyl, n-pentyl, n-hexyl, 2-ethylhexyl, octyl and dodecyl radicals.
5. A compound as defined by claim 1, comprising at least one alkyl radical substituent having from 1 to 20 carbon atoms and selected from the group consisting of methyl, ethyl, propyl, isopropyl, cyclopropyl, n-butyl, i-butyl, t-butyl, n-pentyl, n-hexyl, 2-ethylhexyl, octyl, dodecyl, hexadecyl and octadecyl radicals.
6. A compound as defined by claim 1, comprising at least one monohydroxyalkyl radical selected from the group consisting of hydroxymethyl, 2-hydroxyethyl, 2-hydroxypropyl and 3-hydroxypropyl radicals.
7. A compound as defined by claim 1, comprising at least one polyhydroxyalkyl radical selected from the group consisting of 2,3-dihydroxypropyl, 2,3,4-trihydroxybutyl and 2,3,4,5-tetrahydroxypentyl radicals, or a pentaerythritol residue.
8. A compound as defined by claim 1, comprising at least one polyether radical selected from the group consisting of methoxymethoxy, methoxyethoxy and methoxyethoxymethoxy radicals.
9. A compound as defined by claim 1, comprising at least one aryl radical selected from the group consisting of a phenyl radical optionally substituted with at least one halogen, an (a lower) alkyl radical having from 1 to 6 carbon atoms, a hydroxyl, a C1-C3 alkoxy radical, a nitro function, a polyether radical or an amino function optionally protected with an acetyl group or optionally substituted with at least one alkyl radical having from 1 to 6 carbon atoms or an alkoxy radical having from 1 to 6 carbon atoms.
10. A compound as defined by claim 1, comprising at least one aralkyl radical selected from the group consisting of a benzyl or phenethyl radical optionally substituted with at least one halogen, an alkyl radical having from 1 to 6 carbon atoms, a hydroxyl, an alkoxy radical having from 1 to 3 carbon atoms, a nitro function, a polyether radical or an amino function optionally protected with an acetyl group or optionally substituted with at least one alkyl radical having from 1 to 6 carbon atoms or an alkoxy radical having from 1 to 6 carbon atoms.
11. A compound as defined by claim 1, comprising at least one alkenyl radical having from 2 to 5 carbon atoms and having one or more sites of ethylenic unsaturation.
12. A compound as defined by claim 1, comprising at least one sugar residue selected from the group consisting of the residue derived from glucose, galactose or mannose, or from glucuronic acid.
13. A compound as defined by claim 1, comprising at least one amino acid residue selected from the group consisting of a residue derived from lysine, from glycine or from aspartic acid.
14. A compound as defined by claim 1, comprising at least one amino acid residue selected from the group consisting of a dipeptide or tripeptide residue resulting from the combination of amino acids.
15. A compound as defined by claim 1, selected from the group consisting of:
1. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxybenzoic acid;
2. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
3. 4-2-(3-tert-Butyl-4-pyrrolidin-1-ylphenyl)-2-hydroxyiminoethoxybenzoic acid;
4. 4-2-(3-tert-Butyl-4-pyrrolidin-1-ylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
5. 4-{2-4-(Acetylethylamino)-3-tert-butylphenyl-2-hydroxyiminoethoxy}benzoic acid;
6. 4-{2-4-(Acetylethylamino)-3-tert-butylphenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
7. Ethyl 4-2-(3-tert-butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoate;
8. Isopropyl 4-2-(3-tert-butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoate;
9. Isobutyl 4-2-(3-tert-butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoate;
10. Octyl 4-2-(3-tert-butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoate;
11. Dodecyl 4-2-(3-tert-butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoate;
12. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-hydroxyiminoethoxy-N-ethyl -2-hydroxy-N-methylbenzamide;
13. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-methoxyiminoethoxy-2-hydroxybenzonic acid;
14. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-methylhydrazono)ethoxy-2-hydroxybenzoic acid;
15. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-pentylhydrazono)ethoxy-2-hydroxybenzoic acid;
16. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-2-methanesulfonyliminoethoxy-2-hydroxybenzoic acid;
17. 4-2-(3-tert-Butyl-4-diethylaminophenyl)-2-(pentane-1-sulfonylimino)ethoxy-2-hydroxybenzoic acid;
18. 4-2-(3-tert-Butyl-5-chloro-4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
19. 4-2-(3-tert-Butyl-4-diethylamino-5-fluorophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
20. 4-2-(3-tert-Butyl-4-diethylamino-5-trifluoromethylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
21. 4-2-(3-tert-Butyl-4-diethylamino-5-methylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
22. 4-2-(3-tert-Butyl-4-diethylamino-5-ethylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
23. 4-{2-3-tert-Butyl-4-diethylamino-5-(2-ethoxyethoxy)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
24. 4-2-(3-tert-Butyl-4-diethylamino-5-propoxyphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
25. 4-2-(4-diethylamino-3-isopropylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
26. 4-2-(4-diethylamino-3-trifluoromethylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
27. 4-2-(4-diethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
28. 4-{2-3-tert-Butyl-4-(ethylmethylamino)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
29. 4-2-(3-tert-Butyl-4-dimethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
30. 4-{2-3-tert-Butyl-4-(ethylisobutylamino)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
31. 4-2-(3-tert-Butyl-4-morpholin-4-ylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
32. 4-2-(3-tert-Butyl-4-piperid-1-ylphenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
33. 4-{2-3-tert-Butyl-4-(2-oxopiperid-1-yl)phenyl-2-hydroxyiminoethoxy}benzoic acid;
34. 4-{2-3-tert-Butyl-4-(2-oxopyrrolidin-1-yl)phenyl-2-hydroxyiminoethoxy}benzoic acid;
35. 4-2-(3-tert-Butyl-4-ethylaminophenyl)-2-hydroxyiminoethoxy-2-hydroxybenzoic acid;
36. 4-{2-4-(Ethylpropionylamino)-3-tert-butylphenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
37. 4-{2-3-tert-Butyl-4-(ethoxycarbonylethylamino)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
38. 4-{2-3-tert-Butyl-4-(ethylmethoxycarbonylamino)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
39. 4-{2-4-(Ethyltrifluoroacetylamino)-3-tert-butylphenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid;
40. 4-{2-4-(Trifluoroacetylamino)-3-tert-butylphenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid; and
41 .4-{2-3-tert-Butyl-4-(ethylisopropylamino)phenyl-2-hydroxyiminoethoxy}-2-hydroxybenzoic acid.
16. A compound as defined by claim 1, wherein:
R1 is a radical \u2014OR7;
R2 is a hydrogen or \u2014OH;
R5 and R6, which may be identical or different, are each a methyl radical or an ethyl radical, or together form with the nitrogen atom from which they depend, a pyrrolidine heterocycle;
Q is a radical \u2014OR13.
17. A pharmaceutical composition comprising a pharmaceutically effective amount of at least one compound (I) as defined by claim 1, formulated into a physiologically acceptable support therefor.
18. The pharmaceutical composition as defined by claim 17, comprising from 0.001% to 10% by weight of said at least one compound (I).
19. The pharmaceutical composition as defined by claim 17, comprising from 0.01% to 1% by weight of said at least one compound (I).
20. A cosmetic composition comprising a cosmetically effective amount of at least one compound (I) as defined by claim 1, formulated into a physiologically acceptable support therefor.
21. The cosmetic composition as defined by claim 20, comprising from 0.001% to 3% by weight of said at least one compound (I).
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A UV light source comprising: a plurality of UV light-emitting diodes supported by a wall and arranged in a matrix, wherein the wall includes cooling air apertures that are in communication with a source of cooling air and are situated in the vicinity of the light emitting diodes.
2. The light source of claim 1, wherein the cooling-air apertures are in communication with a distribution chamber which is delimited by a rear wall and by a front wall supporting the light-emitting diodes.
3. The light source of claim 2, wherein the front wall exhibits cooling-air slots extending parallel to one another, the width of which is comparable to the dimension of a light-emitting diode, and in that further light-emitting diodes which are in alignment with the cooling-air slots are provided downstream of the front wall.
4. The light source of claim 2, wherein the distribution chamber have cooling air applied to it via supply slots which are in communication with cooling-air channels.
5. The light source of claim 4, wherein the cooling-air channels re formed by sections of a continuous profiled material.
6. The light source of claim 1, wherein the light-emitting diodes are arranged in densely packed manner.
7. The light source of claim 1, wherein the light-emitting diodes are each arranged downstream of an aperture in a mirror.
8. The light source of claim 7, wherein the mirror exhibits scattering surface irregularities.
9. The light source of claim 7, wherein the mirror exhibits dished or domed surface sections.
10. The light source of claim 9, wherein surface sections situated between the apertures in the mirror are convexly curved.
11. The light source according of claim 9, wherein surface sections of the mirror surrounding the apertures are concavely curved.
12. The light source of claim 1, further comprising a scattering unit arranged upstream of the light-emitting diodes.
13. The light source of claim 7, further comprising a scattering unit arranged upstream of the light-emitting diodes wherein the scattering unit exhibits scattering elements situated upstream of the apertures in the mirror.
14. The light source of claim 13, wherein the scattering element exhibits diminishing scattering power with increasing spacing from the axis of the assigned light-emitting diode.
15. The light source of claim 1, wherein the light-emitting diodes include light-emitting diodes with varying operating wavelength.
16. The light source of claim 1, wherein the light-emitting diodes are arranged in consecutive rows.
17. The light source of claim 16, wherein the light-emitting diodes of consecutive rows are offset in relation to one another.
18. The light source of claim 1, wherein the light-emitting diodes are arranged on a curved separation surface.
19. The light source of claim 1, wherein the light-emitting diodes exhibit a radiation pattern with an aperture angle from about 10\xb0 to about 60\xb0.
20. The light source of claim 1, wherein the light-emitting diodes are arranged on one or more printed circuit boards and the rear of these printed circuit boards is cooled by a cooling fluid.
21. The light source of claim 20, wherein the printed circuit board exhibits on the rear, a metal lamination conducting heat well, with the metal layer forming a plurality of conductive tracks to which the light-emitting diodes are connected, whereas the other metal layer is connected in heat-conducting manner to at least one cooling tube.
22. The light source of claim 21, wherein the printed circuit board carries a plurality of cooling tubes extending substantially parallel to one another which are connected at least one of their ends, by means of a head channel.
23. The light source of claim 1, wherein groups of light emitting diodes are electrically connected in series.
24. The light source of claim 23, wherein the power supply contacts to be poled differently of adjacent light-emitting diodes are connected to one another via conductive tracks of a printed connecting pcb.
25. The light source of claim 1, wherein at least some of the light-emitting diodes are electrically connected in parallel.
26. The light source of claim 25, further comprising a connecting pcb supporting a group of light-emitting diodes and carrying carries two supply busbars parallel to one another, and the light-emitting diodes are rotated in such a way that the connecting lines of their anode contacts and cathode contacts extend at such an angle to the supply busbars that the anode contacts are situated above a first one of the supply busbars and the cathode contacts are situated above the second one of the supply busbars, and heat-dissipating contacts are situated to the side of the supply busbars.
27. A UV light source comprising:
a housing; and,
a plurality of light-emitting diodes arranged in a matrix and supported by a supporting structure, wherein the light-emitting diodes are provided on their mounting side with power supply contacts and with at least one heat-dissipating contact that is in heat-transmitting contact with a heat-dissipating surface of the housing.
28. The light source of claim 27, wherein the light-emitting diodes are arranged in densely packed manner.
29. The light source of claim 27, wherein the light-emitting diodes are each arranged downstream of an aperture in a mirror.
30. The light source of claim 29, wherein the mirror exhibits scattering surface irregularities.
31. The light source of claim 29, wherein the mirror exhibits dished or domed surface sections.
32. The light source of claim 31, wherein surface sections situated between the apertures in the mirror are convexly curved.
33. The light source according of claim 31, wherein surface sections of the mirror surrounding the apertures are concavely curved.
34. The light source of claim 27, further comprising a scattering unit arranged upstream of the light-emitting diodes.
35. The light source of claim 29, further comprising a scattering unit arranged upstream of the light-emitting diodes wherein the scattering unit exhibits scattering elements situated upstream of the apertures in the mirror.
36. The light source of claim 35, wherein the scattering element exhibits diminishing scattering power with increasing spacing from the axis of the assigned light-emitting diode.
37. The light source of claim 27, wherein the light-emitting diodes include light-emitting diodes with varying operating wavelength.
38. The light source of claim 27, wherein the light-emitting diodes are arranged in consecutive rows.
39. The light source of claim 38, wherein the light emitting diodes of consecutive rows are offset in relation to one another.
40. The light source of claim 27, wherein the light-emitting diodes are arranged on a curved separation surface.
41. The light source of claim 27, wherein the light-emitting diodes exhibit a radiation pattern with an aperture angle from about 10\xb0 to about 60\xb0.
42. The light source of claim 27, wherein the light emitting diodes are arranged on one or more printed circuit boards and the rear of these printed circuit boards is cooled by a cooling fluid.
43. The light source of claim 42, wherein the printed circuit board exhibits on the rear, a metal lamination conducting heat well, with the metal layer forming a plurality of conductive tracks to which the light-emitting diodes are connected, whereas the other metal layer is connected in heat-conducting manner to at least one cooling tube.
44. The light source of claim 43, wherein the printed circuit board carries a plurality of cooling tubes extending substantially parallel to one another which are connected at least one of their ends, by means of a head channel.
45. The light source of claim 27, wherein the power supply contacts and the heat-dissipating contacts of the light-emitting diodes are arranged in separate regions of the mounting side of the light-emitting diodes, and the power-supply contacts and heat-dissipating contacts of the light-emitting diodes are each arranged in a common row or column and are orientated in alignment with one another, and the aligned heat-dissipating contacts are in communication with a heat dissipating surface facing towards them.
46. The light source of claim 45, wherein the power supply contacts are connected to a connecting pcb which is arranged in each instance in a receiving groove in the housing, said receiving groove being situated between two adjacent heat-dissipating surfaces.
47. The light source of claim 46, wherein the bottom of the receiving grooves exhibits passageways for supply lines leading to the connecting pcb.
48. The light source of claim 27, wherein the heat dissipating surface is formed on a housing which is traversed by coolant channels.
49. The light source of claim 48, wherein at least some of the coolant channels conduct a liquid coolant, in particular water.
50. The light source of claim 48, wherein at least some of the coolant channels conduct a gaseous coolant, in particular air.
51. The light source of claim 27, further comprising retaining plates wherein by the use thereof, the light-emitting diodes are pressed against the heat-dissipating surfaces which exhibit a window for each of the light emitting diodes.
52. The light source of claim 51, wherein the retaining frames each exhibit a fastening section which is free of windows and in which a fastening means is arranged which cooperates with a housing bearing the heat dissipating surface.
53. The light source of claim 52, wherein the retaining frames are arranged in rows or columns and are offset in relation to one another in the row-direction or column-direction in such a way that substantially the same number of light-emitting diodes is obtained overall in each column or row.
54. The light source of claim 52, wherein the fastening means cooperates with retaining means, which each slightly overlap an adjacent retaining frame.
55. The light source of claim 51, wherein the marginal ends, in the line-direction or column-direction, of several adjacent frames of the peripheral retaining frames are fixed via a retaining strip to a housing bearing the heat dissipating surface.
56. The light source of claim 51, wherein the windows exhibit window walls extending towards the outside of the retaining plate.
57. The light source of claim 51, wherein the retaining frames are provided on two mutually opposing sides with complementary parts of a tongue-and-groove joint.
58. The light source of claim 51, wherein the housing bearing the heat-dissipating surfaces is formed by a section of an extrusion profile which is manufactured from a material that conducts heat well.
59. The light source of claim 58, wherein the extrusion profile is provided with at least one mounting groove.
60. The light source of claim 58, wherein the extrusion profile at least partially delimits an air channel.
61. The light source of claim 58, wherein the extrusion profile at least partially delimits a cable channel.
62. The light source of claim 27, wherein groups of light emitting diodes are electrically connected in series.
63. The light source of claim 61, wherein the power supply contacts to be poled differently of adjacent light-emitting diodes are connected to one another via conductive tracks of a printed connecting pcb.
64. The light source of claim 27, wherein at least some of the light-emitting diodes are electrically connected in parallel.
65. The light source of claim 64, further comprising a connecting pcb supporting a group of light-emitting diodes and carrying carries two supply busbars parallel to one another, and the light-emitting diodes are rotated in such a way that the connecting lines of their anode contacts and cathode contacts extend at such an angle to the supply busbars that the anode contacts are situated above a first one of the supply busbars and the cathode contacts are situated above the second one of the supply busbars, and heat-dissipating contacts are situated to the side of the supply busbars.