Author: claimsbot

1. A composition comprising a silicone-polyoxamide process additive and a thermoplastic with the proviso that the silicone-polyoxamide process additive is not acrylic modified;
wherein the refractive index difference between the silicone-polyoxamide process additive and the thermoplastic is less than about 0.07; and
wherein the weight percent of silicone-polyoxamide process additive based on the total weight of the composition is an amount effective to reduce extrusion melt defects in the thermoplastic.
2. (canceled)
3. The composition of claim 1 wherein the silicone-polyoxamide process additive is selected from:
(a) at least one copolymer comprising at least two repeat units of Formula I-a:
(b) at least one copolymer comprising at least two repeat units of Formula I-b:
(c) and combinations thereof
wherein each R1 is independently an alkyl, haloalkyl, aralkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; each Y is independently an alkylene, aralkylene, or a combination thereof; G is a divalent residue; each group B is selected from a covalent bond, an alkylene of 4-20 carbons, an aralkylene, an arylene, or a combination thereof; n is an integer of 0 to 1500; and p is an integer of 1 to 10.
4. The composition of claim 3 wherein the divalent residue is derived from a diamine having the formula R3HN-G-NHR3, wherein R3 is selected from a hydrogen and an alkyl.
5. The composition of claim 4 wherein the diamine is a heterocyclic group.
6. The composition of claim 1 wherein the silicone-polyoxamide process additive has a molecular weight greater than 50,000.
7. The composition of claim 1 wherein the silicone-polyoxamide process additive polymer has a viscosity of greater than 3160 Pa.
8. The composition of claim 1 wherein the weight percent of the silicone-polyoxamide process additive based on the total weight of the composition is 0.01 wt % to 5.0 wt %.
9. The composition of claim 1 wherein the weight percent of the silicone-polyoxamide process additive is 0.01 wt % to 1.0% wt %.
10. The composition of claim 1 further comprising a synergist.
11. The composition of claim 10 wherein the synergist is i) silicone-polyether copolymers; ii) aliphatic polyesters; iii) aromatic polyesters; iv) polyether polyols; and v) poly(oxyalkylene) polymers.
12. The composition of claim 1 wherein the thermoplastic is selected from polypropylenes, polystyrenes, polyethylenes, polyesters, and combinations thereof.
13. The composition of claim 12 wherein the thermoplastic is a polypropylene.
14. (canceled)
15. An article comprising the composition of claim 1, wherein the article is an extruded film, a bottle, a sheet or a tube.
16. A method of making the article of claim 15 comprising:
a. melt mixing the thermoplastic and the silicone-polyoxamide process additive to form a mixture;
b. extruding the mixture.
17. The method of claim 16 wherein the melt mixing step is done by batch blending or extrusion.
18. The method of claim 16 wherein the silicone-polyoxamide process additive is selected from
(a) at least one copolymer comprising at least two repeat units of Formula I-a:
(b) at least one copolymer comprising at least two repeat units of Formula I-b:
(c) and combinations thereof
wherein each R1 is independently an alkyl, haloalkyl, aralkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; each Y is independently an alkylene, aralkylene, or a combination thereof; G is a divalent residue; each group B is selected from a covalent bond, an alkylene of 4-20 carbons, an aralkylene, an arylene, or a combination thereof; n is an integer of 0 to 1500; and p is an integer of 1 to 10.
19. The method of claim 18 wherein the divalent residue is derived from a diamine having the formula R3HN-G-NHR3, wherein R3 is selected from a hydrogen and an alkyl,
20. The method of claim 19 wherein the diamine is a heterocyclic group.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A system for delivering a coated reconfigurable medical implant to a target site, the system comprising:
a carrier device, the carrier device having a proximal end and a distal end, the distal end having an implant carrying region; and
a reconfigurable deployable coated medical implant in physical communication with the implant carrying region of the carrier device,
the deployable medical implant coated with a coating having therapeutic,
the coating positioned on an exposed surface of the deployable medical implant,
the deployable medical implant reconfigurable from a first expanded configuration to a second contracted configuration,
the therapeutic encased by an encasing hollow deformable membrane,
the membrane, in an unexpanded state, defining a cavity having a cross-section that is smaller than the external cross-section of the deployable medical implant when the medical implant is in its second contracted configuration.
2. The system of claim 1 wherein the reconfigurable deployable medical implant is either a stent, a graft, a stent graft, or a vena cava filter.
3. The system of claim 1 wherein,
the medical implant comprises a frame,
the frame expandable from a first configuration to a second configuration,
the frame having the coating on an external outward facing surface, and

an internal surface of the deformable membrane is in contact with the coating on an external outward facing surface of the medical implant.
4. The system of claim 3 wherein the frame is in communication with a first sock, the sock sized to secure the frame to the implant carrying region of the carrier device, the first sock positioned at an end of the frame.
5. The system of claim 4 wherein the frame is in communication with a second sock,
the second sock at an end of the frame opposite the end of the frame in communication with the first sock,
the second sock sized to secure the frame to the implant carrying region of the carrier device.
6. The system of claim 1 wherein the deformable membrane includes a zip chord,
the zip chord having an accessible graspable portion extending from the deformable membrane.
7. The system of claim 1 wherein the deformable membrane has a cylindrically shaped portion.
8. The system of claim 1 wherein the deformable membrane defines a vessel with a single orifice.
9. The system of claim 1 wherein the deformable membrane has a thickness substantially between 0.3 mm and 0.6 mm.
10. The system of claim 1 wherein the deformable membrane defines a sleeve having a first orifice and a second orifice.
11. The system of claim 1 wherein the deformable membrane also covers at least a portion of a first sock,
the first sock sized to position the medical implant at the implant carrying region of the carrier device.
12. The system of claim 11 wherein the deformable membrane also covers at least a portion of a second sock,
the first sock at an end of the medical implant and the second sock at a different end of the medical implant.
13. The system of claim 1 wherein the carrier device is a balloon catheter.
14. The system of claim 1 wherein the deformable membrane includes an external coating along an outside exposed surface of the deformable membrane.
15. The system of claim 1 wherein the deformable membrane is covered with a protective covering.
16. The system of claim 15 wherein the protective covering is a monofilament nylon braided sleeve.

1. An information processing apparatus with a processor, the information processing apparatus comprising:
an instruction unit configured to instruct, using the processor, changing of layout for document data including a first page on which objects are arranged and a second page following the first page;
a display control unit configured to display, using the processor, a definition screen to define a page range;
a definition unit configured to define, using the processor, a page number as the page range of changing target in accordance with instruction input via the definition screen;
a reducing unit configured to reduce a distance between the objects arranged on a first page included in the page range to a predetermined distance shorter than the distance between the objects arranged on the first page when the changing of layout is instructed;
an arranging unit configured to arrange an object arranged on the second page in a space of the first page generated by reducing the distance between the objects arranged on the first page to the predetermined distance;
a determining unit configured to determine whether a ratio of the object arranged on the second page exceeds a threshold value; and
an eliminating unit configured to eliminate the second page by arranging the object arranged on the second page in the space of the first page,
wherein the reducing unit is configured to reduce the distance between the objects arranged on the first page included in the page range to the predetermined distance when the determining unit determines that the ratio does not exceed the threshold value.
2. The information processing apparatus according to claim 1, further comprising:
a setting unit configured to set a priority for a gap between the objects, wherein the reducing unit is configured to reduce the distance of the gap between the objects in a priority order from low to high based on the priority set by the setting unit.
3. An information processing method comprising:
instructing changing of layout for document data including a first page on which objects are arranged and a second page following the first page;
displaying, using a processor, a definition screen to define a page range;
defining, using the processor, a page number as the page range of changing target in accordance with instruction input via the definition screen;
reducing a distance between the objects arranged on a first page included in the page range to a predetermined distance shorter than the distance between the objects arranged on the first page when the changing of layout is instructed;
arranging an object arranged on the second page in a space of the first page generated by reducing the distance between the objects arranged on the first page to the predetermined distance;
determining whether a ratio of the object arranged on the second page exceeds a threshold value; and
eliminating the second page by arranging the object arranged on the second page in the space of the first page,
wherein the reducing unit is configured to reduce the distance between the objects arranged on the first page included in the page range to the predetermined distance when the determining unit determines that the ratio does not exceed the threshold value.
4. The information processing method according to claim 3, further comprising:
setting a priority for a gap between the objects, wherein reducing a distance of the gap between the objects arranged on a first page comprises reducing the distance between the objects in a priority order from low to high based on the priority set.
5. A computer readable device storing a program for causing an information processing apparatus to perform an information processing method comprising:
instructing changing of layout for document data including a first page on which objects are arranged and a second page following the first page;
displaying a definition screen to define a page range;
defining a page number as the page range of changing target in accordance with instruction input via the definition screen;
reducing a distance between the objects arranged on a first page included in the page range to a predetermined distance shorter than the distance between the objects arranged on the first page when the changing of layout is instructed;
arranging an object arranged on the second page in a space of the first page generated by reducing the distance between the objects arranged on the first page to the predetermined distance;
determining whether a ratio of the object arranged on the second page exceeds a threshold value; and
eliminating the second page by arranging the object arranged on the second page in the space of the first page,
wherein the reducing unit is configured to reduce the distance between the objects arranged on the first page included in the page range to the predetermined distance when the determining unit determines that the ratio does not exceed the threshold value.
6. The computer readable device according to claim 5, wherein the method further comprises:
setting a priority for a gap between the objects, wherein reducing a distance of the gap between the objects arranged on a first page comprises reducing the distance between the objects in a priority order from low to high based on the priority set.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method for detecting the presence of cervical dysplasia in a subject, the method comprising
a) contacting a cervical sample from a subject with a reagent or reagents for detecting a level of at least one target RNA, wherein the at least one target RNA:
(i) is capable of specifically hybridizing to a nucleic acid having a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(ii) comprises a sequence that is complementary to at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(iii) comprises at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 345 to 388;

b) comparing the level of the at least one target RNA to a normal level of the RNA; and
c) detecting the presence of cervical dysplasia in the subject when the level of the at least one target RNA in the sample is greater than a normal level of the at least one target RNA.
2. (canceled)
3. A method for facilitating the detection of cervical dysplasia in a subject, comprising:
(a) contacting a cervical sample from a subject with a reagent or reagents for detecting a level of at least one target RNA, wherein the at least one target RNA:
(i) is capable of specifically hybridizing to a nucleic acid having a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(ii) comprises a sequence that is complementary to at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(iii) comprises at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 345 to 388; and

(b) comparing the level of the at least one target RNA to a normal level of the RNA; and
(c) communicating the results of (b) to a medical practitioner for the purpose of determining whether the subject has cervical dysplasia.
4. The method of claim 1, wherein detecting a level of at least one target RNA in a sample comprises:
(a) hybridizing nucleic acids of the sample with at least one polynucleotide that is complementary to a target RNA in the sample or to a complement thereof; and
(b) detecting at least one complex comprising a polynucleotide hybridized to at least one nucleic acid selected from the target RNA, a DNA amplicon of the target RNA, and a complement of the target RNA.
5. (canceled)
6. The method of claim 1, wherein the method further comprises isolating nucleic acids from the cervical sample.
7. The method of claim 6, wherein the nucleic acids comprise RNA that has been separated from DNA.
8. The method of claim 1, wherein at least one target RNA in its mature form comprises fewer than 30 nucleotides.
9. The method of claim 1, wherein at least one target RNA is a microRNA.
10. The method of claim 1, wherein levels of at least two target RNAs are detected, wherein at least two of the target RNAs:
(i) are capable of specifically hybridizing to a nucleic acid having a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(ii) comprise a sequence that is complementary to at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(iii) comprise at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 345 to 388; and

wherein the at least two target RNAs are different.
11-12. (canceled)
13. The method of claim 10, wherein levels of at least three target RNAs are detected, wherein at least three of the target RNAs:
(i) are capable of specifically hybridizing to a nucleic acid having a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(ii) comprise a sequence that is complementary to at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 1 to 41 and 133 to 211; or
(iii) comprise at least 15 contiguous nucleotides of a sequence selected from SEQ ID NOs: 345 to 388; and

wherein the at least three target RNAs are different.
14-16. (canceled)
17. The method of claim 10, wherein levels of at least five target RNAs are detected.
18. (canceled)
19. The method of claim 1, wherein the method further comprises detection of a level of at least one target RNA that is an mRNA.
20. The method of claim 19, wherein the mRNA is selected from CDKN2A, MKI67, TOP2A, MCM5, BIRC5, MMP9, and MCM2.
21.-24. (canceled)
25. A synthetic polynucleotide comprising a first region, wherein the first region comprises a sequence of at least 8 contiguous nucleotides that is identical or complementary to a sequence of at least 8 contiguous nucleotides of one of SEQ ID NOs: 1 to 7, 9 to 37, 133 to 201, and 345 to 388.
26-27. (canceled)
28. The synthetic polynucleotide of claim 25, wherein the first region comprises a sequence of at least 12 contiguous nucleotides that is identical or complementary to a sequence of at least 12 contiguous nucleotides of one of SEQ ID NOs: 1 to 7, 9 to 37, 133 to 201, and 345 to 388.
29. The synthetic polynucleotide of claim 25, wherein the polynucleotide comprises a detectable label.
30. The synthetic polynucleotide of claim 29, wherein the detectable label is a FRET label.
31. (canceled)
32. The synthetic polynucleotide of claim 25, wherein the polynucleotide further comprises a second region that is not identical or complementary to a region of the target RNA.
33-36. (canceled)
37. A kit comprising a synthetic polynucleotide of claim 25.
38. (canceled)
39. The kit of claim 37, wherein the kit further comprises at least one polymerase.
40. The kit of claim 37, wherein the kit further comprises dNTPs.
41. The method of claim 1, wherein the reagent is selected from a probe that specifically hybridizes to the RNA, a primer or primers for reverse transcribing the RNA into cDNA, a primer or primers for amplifying the cDNA, a microarray comprising at least one nucleic acid that hybridizes to the RNA or cDNA reverse transcribed from the RNA, and a primer for sequencing the RNA or cDNA reverse transcribed from the RNA.