1460746536-c635dc2c-2c75-44ea-b765-54f77bb259fc

1. A cartridge assembly for reducing the base drag of a projectile in flight, comprising:
a. a low pressure case, having a base and an open end;
b. a high pressure cartridge inserted within said base of said low pressure case, having a closed first end, an open second end, and a continuous side wall running between said first and second ends, thereby defining a hollow interior;
c. propellant, contained within said hollow interior of said high pressure cartridge;
d. a burstable sealing member sealing said open second end of said high pressure cartridge, thereby closing said hollow interior within said high pressure cartridge;
e. wherein said low pressure case includes a charge casing surrounding said high pressure cartridge;
f. a projectile assembly seated in said open end of said low pressure case;
g. wherein said projectile assembly includes an aft closure having an aft opening;
h. wherein said aft closure includes a volume of gas generating material sufficient to inject pressurizing gas into the wake of said projectile assembly, through said aft opening, for a substantial portion of said flight of said projectile;
i. wherein said low pressure case further includes a charge vent hole positioned to direct hot propellant gas from said high pressure cartridge toward said aft opening in said aft closure;
j. said gas generating material being contained within a cavity in said aft closure;
k. said aft opening lying at the aft extreme of said cavity;
l. said aft closure including a forward extreme including a bulkhead;
m. said bulkhead opening into an output allowing fluid communication between said cavity and the area forward of said bulkhead;
n. an igniter charge located proximate said output opening;
o. an ignitable payload located forward of said bulkhead and configured to be ignited by said igniter charge, said ignitable payload having an interior cavity; and
p. a piece of ignition material having a forward portion and an aft portion, said piece of ignition material being located within said interior cavity in said ignitable payload, with said aft portion of said ignition material being proximate said igniter charge.
2. A cartridge assembly as recited in claim 1, wherein said ignitable payload comprises
a volume of illuminant composition proximate said piece of ignition material.
3. A cartridge assembly as recited in claim 1, wherein said bulkhead in said aft closure further comprises a plurality of secondary vents allowing fluid communication between said cavity and the area forward of said bulkhead.
4. A cartridge assembly as recited in claim 3, wherein said plurality of secondary vents are arranged in a radial array around said output opening.
5. A cartridge assembly as recited in claim 1 wherein said ignitable payload includes an explosive charge.
6. A cartridge assembly as recited in claim 2, wherein said ignitable payload includes an explosive charge.
7. A cartridge assembly as recited in claim 1 wherein said ignitable payload includes a volume of smoke material.
8. A cartridge assembly as recited in claim 1, wherein said ignitable payload includes an explosive charge.
9. A cartridge assembly as recited in claim 1, wherein said cavity further comprises at least one mechanical interference feature configured to retain said gas generating material within said cavity.
10. A cartridge assembly as recited in claim 2, wherein said cavity further comprises at least one mechanical interference feature configured to retain said gas generating material within said cavity.
11. A cartridge assembly for reducing the base drag of a projectile in flight, comprising:
a. a low pressure case, having a base and an open end;
b. a high pressure cartridge inserted within said base of said low pressure case, said high pressure cartridge having a hollow interior;
c. propellant, contained within said hollow interior of said high pressure cartridge;
d. a burstable sealing member sealing said high pressure cartridge;
e. a projectile assembly seated in said open end of said low pressure case;
f. wherein said projectile assembly includes an aft closure having an aft opening;
g. wherein said aft closure includes a volume of gas generating material sufficient to inject pressurizing gas into the wake of said projectile assembly, through said aft opening, for a substantial portion of said flight of said projectile;
h. wherein said low pressure case further includes a charge vent hole positioned to direct hot propellant gas from said high pressure cartridge toward said aft opening in said aft closure;
i. said gas generating material being contained within a cavity in said aft closure;
j. said aft opening lying at the aft extreme of said cavity;
k. said aft closure including a forward extreme including a bulkhead;
l. said bulkhead opening into an output allowing fluid communication between said cavity and the area forward of said bulkhead;
m. an igniter charge located proximate said output opening;
n. an ignitable payload located forward of said bulkhead and configured to be ignited by said igniter charge, said ignitable payload having an interior cavity; and
o. a piece of ignition material having a forward portion and an aft portion, said piece of ignition material being located within said interior cavity in said ignitable payload, with said aft portion of said ignition material being proximate said igniter charge.
12. A cartridge assembly as recited in claim 11, wherein said ignitable payload comprises a volume of illuminant composition proximate said piece of ignition material.
13. A cartridge assembly as recited in claim 11, wherein said bulkhead in said aft closure further comprises a plurality of secondary vents allowing fluid communication between said cavity and the area forward of said bulkhead.
14. A cartridge assembly as recited in claim 11, wherein said plurality of secondary vents are arranged in a radial array around said output opening.
15. A cartridge assembly as recited in claim 11 wherein said ignitable payload includes an explosive charge.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method of diagnosing preeclampsia in a subject, the method comprising the steps of:
(a) contacting a biological sample from the subject with a reagent that specifically binds to at least one marker selected from the group consisting of the nucleic acid and corresponding protein sequences shown in FIG. 3, FIG. 4, or Table 4; and
(b) determining whether or not the marker is overexpressed or underexpressed in the sample; thereby providing a diagnosis for preeclampsia.
2. The method of claim 1, wherein the reagent is an antibody.
3. The method of claim 2, wherein the antibody is monoclonal.
4. The method of claim 1, wherein the reagent is a nucleic acid.
5. The method of claim 1, wherein the reagent is an oligonucleotide.
6. The method of claim 1, wherein the reagent is an RT PCR primer set.
7. The method of claim 1, wherein the sample is a placental biopsy.
8. The method of claim 1, wherein the sample is a blood sample.
9. The method of claim 1, wherein the sample is a urine sample.
10. The method of claim 1, wherein the sample is a saliva sample.
11. The method of claim 1, wherein the sample is cervicovaginal fluid.
12. A method of providing a prediction for the risk for developing preeclampsia in a subject, the method comprising the steps of:
a) contacting a biological sample from the subject with a reagent that specifically binds to at least one marker selected from the group consisting of the nucleic acid and corresponding protein sequences shown in FIG. 3, FIG. 4, or Table 4; and
(b) determining whether or not the marker is overexpressed or underexpressed in the sample; thereby providing a prediction for preeclampsia development.
13. The method of claim 12, wherein the reagent is an antibody.
14. The method of claim 13, wherein the antibody is monoclonal.
15. The method of claim 12, wherein the reagent is a nucleic acid.
16. The method of claim 12, wherein the reagent is an oligonucleotide.
17. The method of claim 12, wherein the reagent is an RT PCR primer set.
18. The method of claim 12, wherein the sample is a placental biopsy.
19. The method of claim 12, wherein the sample is a blood sample.
20. The method of claim 12, wherein the sample is a urine sample.
21. The method of claim 12, wherein the sample is a saliva sample.
22. The method of claim 12, wherein the sample is cervicovaginal fluid.
23. The method of claim 12, wherein the prediction is a prognosis for the development of preeclampsia during a preexisting pregnancy or recurrence of preeclampsia during a subsequent pregnancy.
24. A method of identifying a compound that prevents or treats preeclampsia, the method comprising the steps of:
(a) contacting a compound with a sample comprising a cell that expresses a marker selected from the group consisting of the nucleic acid and corresponding protein sequences shown in FIG. 3, FIG. 4, or Table 4; and
(b) determining the functional effect of the compound on the marker, thereby identifying a compound that prevents or treats preeclampsia.
25. The method of claim 24, wherein the compound is a small molecule.
26. The method of claim 24, wherein the compound is a siRNA.
27. The method of claim 24, wherein the compound is a ribozyme.
28. The method of claim 24, wherein the compound is an antibody.
29. The method of claim 28, wherein the antibody is monoclonal.

1460746528-8dee49e5-8e6e-4664-ba7c-5ea01a3f895d

1. A financial transaction system comprising:
at least one financial institution transaction processing system;
at least one hub server operable to transmit data to and receive data from said financial institution transaction processing system;
at least one web server operable to transmit data to and receive data from
at least one user via an open network, said web server operable to transmit data to and receive data from said hub server;
at least one database server operable to transmit data to and receive data from said hub server and said web server, said database server capable of storing data in a hub database;
said hub server operable to map data received from said financial institution into mapped data and load said mapped data onto said hub database;
said web server operable to:
receive said mapped data from said hub database;
transmit said mapped data onto said user over the open network;
receive a financial transaction message from said user over the open network, the financial transaction message relating to said mapped data conforming to one of a plurality of transaction type profiles;
select a unified transaction format based on the transaction type profile of the transaction;
generate a unified transaction message by converting the transaction message to the unified transaction format;
provide the unified transaction message to the database server for storage in the hub database and to the hub server for delivery to the financial institution transaction processing system;

said hub server further operable to:
look up a financial institution transaction format associated with both the transaction type profile and the financial institution processing;
reformat the unified transaction to the financial institution transaction format; and
route said reformatted transaction to the financial institution transaction processing system.
2. The financial transaction system of claim 1, further comprising a data archive, said archive operable to remove data from said hub database andor said application database, index said data, and store said data for future retrieval.
3. The financial transaction system of claim 2, wherein said web server further comprises a mechanism allowing said user to at least one of enter and modify the financial transaction message at a time prior to a transaction execution date specified in the financial transaction message, such mechanism performing the steps of:
receiving an instruction message to at least one of enter, modify, and delete the financial transaction message, the instruction message specifying the financial transaction message;
generating a modified unified transaction message combining: i) the unified transaction message corresponding to the specified financial transaction message; and

ii) the instruction message; and
storing the modified unified transaction message in the application database.
4. The financial transaction system of claim 3, wherein said web server is operable to require approval by a predetermined number of remote approvers prior to providing the unified transaction message to the hub server, the web server performing the steps of:
determining each remote approver required to approve the financial transaction message based on an identity of the user providing the financial transaction message and the transaction type profile;
duplicating the unified transaction message in an approval queue for each remote approver;
receiving an instruction to execute said transaction from each remote approver;
storing each instruction to execute said transaction in the hub database;
routing the unified transaction message to the hub server only after an instruction to execute the transaction has been approved by each remote approver.
5. The financial transaction system of claim 4, wherein said web server is operable to prevent processing of a financial transaction message until the execution date specified in said financial transaction message matches the current date by routing the unified transaction message to the hub server only when the specified execution date matches the current date.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1-10. (canceled)
11. A switchgear comprising:
a primary disconnecting switch and a secondary disconnecting switch respectively arranged on a primary side and a secondary side of a load switch or a voltage and current transformer for an instrument,
a primary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said primary disconnecting switch,
a secondary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said secondary disconnecting switch,
a connection means linked to said primary and secondary disconnecting switches and said primary and secondary grounding switches to move moving electrodes of said disconnecting switches and those of said grounding switches, and
an operation device which operates said moving electrodes in connection with each other via said connection means,
wherein said primary and secondary disconnecting switches or said primary and secondary grounding switches connect or disconnect to each other with a time difference at switching operation.
12. A switchgear according to claim 11, wherein
said connection means is connected to each of said primary and secondary disconnecting switches and each of said primary and secondary grounding switches so that when said primary disconnecting switch and said secondary disconnecting switch are in a \u201cclosed\u201d state, said primary switch and said secondary grounding switch are put into an \u201copen\u201d state, or when said primary grounding switch and said secondary grounding switch are in a \u201cclosed\u201d state, said primary disconnecting switch and said secondary disconnecting switch are put into an \u201copen\u201d state, or when said primary disconnecting switch and said secondary disconnecting switch are in an \u201copen\u201d state, said primary grounding switch and said secondary grounding switch are put into an \u201copen\u201d state.
13. A switchgear comprising;
a primary disconnecting switch and a secondary disconnecting switch respectively arranged on a primary side and a secondary side of a load switch or a voltage and current transformer for an instrument,
a primary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said primary disconnecting switch,
a secondary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said secondary disconnecting switch,
a drive structure for operating said primary and secondary disconnecting switches and said primary and secondary grounding switches in connection with each other and adjusting a start time or an end time of said operation, and
an operation device for driving each of said primary and secondary disconnecting switches and each of said primary and secondary grounding switches,
wherein said primary and secondary disconnecting switches or said primary and secondary grounding switches connect or disconnect to each other with a time difference at switching operation.
14. A switchgear comprising;
a primary disconnecting switch and a secondary disconnecting switch respectively arranged on a primary side and a secondary side of a load switch or a voltage and current transformer for an instrument,
a primary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said primary disconnecting switch,
a secondary-grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said secondary disconnecting switch,
drive levers connected to moving electrodes of said primary and secondary disconnecting switches and said primary and secondary grounding switches for driving said moving electrodes,
drive shafts for driving said drive levers,
first relay levers for rotating said drive shafts,
link rods for driving said first relay levers,
second relay levers for driving said link rods,
a relay shaft for driving said second relay levers,
an operation device for rotating said relay shaft, and
a drive structure for driving said moving electrodes of said primary and secondary disconnecting switches and said primary and secondary grounding switches in connection with each other by rotation of said relay shaft,
wherein said primary and secondary disconnecting switches or said primary and secondary grounding switches connect or disconnect to each other with a time difference at switching operation.
15. A switchgear comprising;
a primary disconnecting switch and a secondary disconnecting switch respectively arranged on a primary side and a secondary side of a load switch or a voltage and current transformer for an instrument,
a primary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said primary disconnecting switch,
a secondary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said secondary disconnecting switch,
a three-position switching means for driving fixed electrodes of said primary and secondary disconnecting switches and said primary and secondary grounding switches so as to freely switch,
a drive lever for driving said three-position switch means,
a drive shaft for driving said drive lever,
an operation lever for rotating said drive shaft, and
a drive structure for driving moving electrodes of said circuit breakers and said grounding switches in connection with each other by driving of said operation lever,
wherein said primary and secondary disconnecting switches or said primary and secondary grounding switches connect or disconnect to each other with a time difference at switching operation.
16. A switchgear comprising:
a primary disconnecting switch and a secondary disconnecting switch respectively arranged on a primary side and a secondary side of a load switch or a voltage and current transformer for an instrument,
a primary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said primary disconnecting switch,
a secondary grounding switch arranged between said load switch or said voltage and current transformer for an instrument and said secondary disconnecting switch,
a three-position switching means for driving fixed electrodes of said primary and secondary disconnecting switches and said primary and secondary grounding switches so as to freely switch,
a drive lever for driving said three-position switching means,
a drive shaft for driving said drive lever,
a first relay lever for rotating said drive shaft,
a first link rod for driving said first relay lever,
a second relay lever for driving said first link rod,
a relay shaft for driving said second relay lever,
a third relay lever for rotating said relay shaft,
a second link rod for driving said third relay lever,
an operation device for driving said second link rod, and
a drive means for driving moving electrodes of said primary and secondary disconnecting switches and said primary and secondary grounding switches in connection with each other by driving of said second link rod,
wherein said primary and secondary disconnecting switches or said primary and secondary grounding switches connect or disconnect to each other with a time difference at switching operation.