Author: claimsbot

1. A screening apparatus for screening pulp suspensions, comprising:
a housing,
a tubular screen basket dividing the interior of the housing into a central chamber and an outer substantially annular chamber, the screen basket including at least two separate tubular screen sections,
an inlet member for supplying a suspension to be screened into one of the central chamber and outer chamber,
an accept outlet member for discharging a developed accept fraction of the suspension that has passed through the screen basket,
a reject outlet member for discharging a developed reject fraction of the suspension,
a rotor arranged in the housing for providing pressure and suction pulses in the suspension to be screened along the screen basket, and
dilution means for supplying diluting liquid to one of the central chamber or outer chamber, the dilution means including at least one annular element axially interconnecting the two tubular screen sections and forming a tubular dilution liquid compartment extending at least substantially around the screen basket, the annular element forming a plurality of dilution liquid ejection passages between the dilution liquid compartment and one of the central chamber and outer chamber.
2. A screening apparatus according to claim 1, wherein one of the accept outlet member and reject outlet member forms an outlet passage from the outer chamber, and the dilution means comprises at least one dilution liquid supply conduit extending through the outlet passage to the annular element, to supply dilution liquid from outside the housing to the dilution liquid compartment.
3. A screening apparatus according to claim 2, further comprising an outlet pipe releasably connected to the outlet member that forms said outlet passage, wherein the dilution liquid supply conduit extends from outside the housing through the wall of the outlet pipe into the outlet passage.
4. A screening apparatus according to claim 1, wherein the dilution means comprises first and second dilution liquid supply conduits connected to the annular element at different places thereon.
5. A screening apparatus according to claim 1, wherein the tubular dilution liquid compartment extends in a closed loop around the central chamber, and the dilution liquid supply conduit is arranged to direct the dilution liquid into the dilution liquid compartment such that the dilution liquid flows in one direction along said closed loop.
6. A screening apparatus according to claim 4, wherein the tubular dilution liquid compartment extends in a closed loop around the central chamber, and the first and second dilution liquid supply conduits are arranged to direct the dilution liquid into the dilution liquid compartment such that the dilution liquid flows in one direction along said closed loop.
7. A screen basket comprising.
a tubular mantle wall provided with screen holes and including at least two separate tubular wall sections, and
dilution means for supplying dilution liquid to one of the inside and outside of the tubular mantle wall, the dilution means including at least one annular element axially interconnecting the two tubular wall sections of the mantle wall and forming a tubular dilution liquid compartment extending at least substantially around the tubular mantle wall,
wherein the annular element forms a plurality of dilution liquid ejection passages between the dilution liquid compartment and one of the inside and outside of the screen basket.
8. A screen basket according to claim 7, wherein the ejection passages have circular cross-sections.
9. A screen basket according to claim 7, wherein the ejection passages take the shape of slots.
10. A screen basket according to claim 7, wherein the tubular dilution liquid compartment has a rectangular cross-section.
11. A screen basket according to claims 7, wherein the dilution means comprises first and second dilution liquid supply inlets on the annular element positioned at different places thereon.
12. A screen basket according to claims 7, wherein the tubular dilution liquid compartment extends in a closed loop around the tubular mantle wall.
13. A method of screening a pulp suspension by the use of a screening apparatus having a tubular screen basket, the method comprises:
feeding the suspension to be screened to one of the external side and internal side of the screen basket,
screening the suspension along a primary screening section of the screen basket to obtain a primary accept fraction that passes through the screen basket and a primary reject fraction that is prevented from passing through the screen basket,
supplying a flow of dilution liquid to dilute the primary reject fraction,
screening the diluted primary reject fraction along a secondary screening section of the screen basket to obtain a secondary accept fraction that passes through the screen basket and a secondary reject fraction that is prevented from passing through the screen basket,
discharging the secondary reject fraction from the screen basket,
combining the primary and secondary accept fractions to form a common final accept fraction, and
controlling the flow of dilution liquid being supplied in response to the consistency and flow of the suspension being fed to the screen basket and the consistency and flow of the secondary reject fraction being discharged from the screen basket, so that the consistency of the primary reject fraction entering the secondary screening section becomes substantially the same as the consistency of the suspension being fed to the screen basket.
14. A method according to claim 13, wherein the suspension to be screened is fed into the internal side of the screen basket and is screened so that the primary reject fraction develops inside the screen basket, whereby the flow of dilution liquid is supplied to the inside of the screen basket and the secondary reject fraction develops inside the screen basket.
15. A method according to claim 13 or 14, further comprising supplying the flow of dilution liquid in the form of jets having a velocity in the range of 2-10 ms, preferably 4-8 ms.
16. A method of screening a pulp suspension by the use of a screening apparatus having a tubular screen basket with perforations, the method comprises:
feeding the suspension to be screened to one of the external side and internal side of the screen basket,
screening the suspension along a primary screening section of the screen basket to obtain a primary accept fraction that passes through the screen basket and a primary reject fraction that is prevented from passing through the screen basket,
supplying a first flow of dilution liquid to dilute the primary reject fraction,
screening the diluted primary reject fraction along a secondary screening section of the screen basket to obtain a secondary accept fraction that passes through the screen basket and a secondary reject fraction that is prevented from passing through the screen basket,
supplying a second flow of dilution liquid to dilute the secondary reject fraction,
screening the diluted secondary reject fraction along a tertiary screening section of the screen basket to obtain a tertiary accept fraction that passes through the screen basket and a tertiary reject fraction that is prevented from passing through the screen basket,
discharging the tertiary reject fraction from the screen basket,
combining the primary, secondary and tertiary accept fractions to form a common final accept fraction, and
controlling the first and second, respectively, flow of dilution liquid being supplied to the screen basket in response to the consistency and flow of the suspension being fed to the screen basket and the consistency and flow of the tertiary reject fraction being discharged from the screen basket, so that the consistency of the primary reject fraction entering the secondary screening section and the consistency of the secondary reject fraction entering the tertiary screening section, respectively, becomes substantially the same as the consistency of the suspension being fed to the screen basket.
17. A method according to claim 16, wherein the suspension to be screened is fed into the internal side of the screen basket and is screened so that the primary reject fraction develops inside the screen basket, whereby the first and second flows of dilution liquid are supplied to the inside of the screen basket and the secondary and tertiary reject fractions develop inside the screen basket.
18. A method according to claim 16, further comprising supplying the first and second flows of dilution liquid in the form of jets having a velocity in the range of 2-10 ms, preferably 4-8 ms.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A fuel cell system, comprising:
a fuel cell stack in a hot zone, the fuel cell stack comprising a plurality of fuel cells and a plurality of interconnects; and
a module comprising a plurality of bypass elements, the module attached to the fuel cell stack and located in the hot zone,
wherein:
at least one of the plurality of bypass elements is electrically connected to at least two of the plurality of interconnects so as to bypass at least one of the plurality of fuel cells located between the interconnects;
each of the plurality of interconnects comprise at least one recess;
the bypass module comprise at least one protrusion; and
the bypass module is attached to the fuel cell stack by inserting the at least one protrusion into the at least one recess.

1. A method for treating a tumor chosen from breast cancer, squamous carcinoma, cell lung cancer, ovarian cancer, stomach cancer, and pancreatic cancer, the method comprising the step of administering to a patient in need of treatment 0.05-100 mgkg of bodyweight daily a compound of formula I, or a pharmaceutically acceptable salt thereof:
wherein, R1 is selected from:
(a) C1-C4 alkyl, C1-C4 alkyl substituted by halogens, C1-C4 alkoxy, C1-C4 alkoxy substituted by halogens, methoxyethoxy, N-morpholinopropoxy, formate, acetate, propionate, butyrate, acylamino or sulfonamide group;
(b) Unsubstituted or substituted phenyl, wherein the substituents are 1-3 substituents selected from the group consisting of halogen, \u2014OH, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkyl-OH, C1-C4 alkoxymethyl, acetate, propionate, butyrate, and sulfonate;
(c) Unsubstituted or substituted furyl, and unsubstituted or substituted thienyl, wherein the substituents are 1-3 substituents selected from the group consisting of halogen, \u2014OH, \u2014NH2, C1-C4 alkyl, C1-C4 alkoxy, alkoxymethyl, formate, acetate, propionate, butyrate, and sulfonate;
or R1 is
wherein R1 is attached to the ring via oxygen, and X is selected from furyl, pyrrolidyl, pyridyl, oxazoline, thiazolyl, and thienyl;
R1\u2032 is selected from hydrogen, C1-C4 alkyl, C1-C4 alkyl substituted by halogens, C1-C4 alkoxy, and C1-C4 alkoxy substituted by halogens;
R2 is selected from benzyl, mono-, di- or tri-halobenzyl, benzoyl, pyridylmethyl, pyridylmethoxy, benzyloxy, mono-, di, -or tri-halobenzyloxy or mono-, di- or tri-halophenylsulfonyl, furylmethyl, pyrrolylmethyl, pyrrolylmethoxy, halogen, C1-C4 alkyl and C1-C4 alkoxy, wherein said phenyl, benzyl, pyridyl, furyl or pyrrolyl may have 1-3 substituents selected from the group consisting of halogen, \u2014OH, \u2014NH2, C1-C4 alkyl and C1-C4 alkoxy;
R2\u2032 is selected from benzyl, mono-, di- or tri-halobenzyl, benzoyl, pyridylmethyl, pyridylmethoxy, phenoxy, mono-, di- or tri-halophenoxy or mono-, di-, or tri-halophenylsulfonyl, furylmethyl, pyrrolylmethyl, pyrrolylmethoxy, halogen, C1-C4 alkyl and C1-C4 alkoxy, wherein said phenyl, benzyl, pyridyl, furyl or pyrrolyl may have 1-3 substituents selected from the group consisting of halogen, \u2014OH, \u2014NH2, C1-C4 alkyl and C1-C4 alkoxyl.
2. The method according to claim 1, wherein
R2 is selected from benzyloxy, mono-, di- or tri-halobenzyloxy; and
R2\u2032 is halogen.
3. The method according to claim 2, wherein
R1 is selected from C1-C4 alkoxy, C1-C4 alkoxy
Substituted by halogens, methoxyethoxy, N-morpholinopropoxy, formate, acetate, propionate, butyrate, acylamino, sulfonamide group, phenyl, furyl,
or R1 is
\u2003wherein X is furyl.
4. The method according to claim 3, wherein
R1 is acylamino:
wherein R3 is selected from hydrogen, N,N-dimethyl aminomethyl, N,N-diethylaminomethyl, N,N-dipropylaminomethyl and N-morpholinomethyl.
5. The method according to claim 4, wherein
R1 is acylamino:
wherein R3 is selected from hydrogen and N,N-dimethylaminomethyl.
6. The method according to claim 1, wherein the compound of formula I is selected from the group consisting of:
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-quinazolin-6-yl}-acrylamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-quinazolin-6-yl}-4-methylbenzenesulfonamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-quinazolin-6-yl}-E,4-(dimethylamino)-but-2-enamide;
N-4-(3-chloro-4-benzyloxy-phenylamino)-quinazolin-6-yl-E,4-(dimethylamino)-but-2-enamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-7-trifluoroethoxy-quinazolin-6-yl}-E,4-(dimethylamino)-but-2-enamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-7-methoxy-quinazolin-6-yl}-E,4-(dimethylamino)-but-2-enamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-7-methoxy-quinazolin-6-yl}-acrylamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-7-chloro-quinazolin-6-yl}-E,4-(dimethylamino)-but-2-enamide;
N-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-7-chloro-quinazolin-6-yl}-acrylamide;
O-{4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-quinazolin-6-yl}-acetate;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(3-oxo-butoxy)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-3-(4-morpholino)-propoxy-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6,7-dimethoxy-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(4-methoxy-phenyl)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(3-hydroxymethyl-phenyl)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(3-acetoxymethyl-phenyl)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-3-(3-oxo-butoxymethyl)-phenyl-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(5-hydroxymethylfuran-2-yl)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(5-methanesulfonyloxymethylene-furan-2-yl)-quinazoline;
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-(5-dimethylaminomethyl-furan-2-yl-methoxy)-quinazoline; and
4-3-chloro-4-(3-fluorobenzyloxy)-phenylamino-6-3-(4-morpholino)propoxy)-7-methoxy-quinazoline.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. An optical transceiver integrated circuit (IC) comprising:
a single IC substrate having multiple cells integrated on the single IC substrate and the multiple cells being vertically arranged with respect to each other and to the single IC substrate, each cell being optically isolated from each other cell with at least one cell being configured to operate at one bitrate and at least another cell being configured to operate an another, different bitrate, each cell including:
an optoelectronic transducer on an optoelectronic transducer substrate and being optically coupled to an optoelectronic transducer optical port that is configured to be operably coupled to a first optical fiber of a network, the optoelectronic transducer substrate being mounted on the IC substrate; and
an electro-optic transducer on an electro-optic transducer substrate and being optically coupled to an electro-optic transducer optical port that is configured to be operably coupled to a second optical fiber of the network, the electro-optic transducer substrate being mounted on the IC substrate;

a post-amplifier integrated on the IC substrate and configured for communication with the optoelectronic transducer;
an electro-optic transducer driver integrated on the IC substrate and configured for communication with the electro-optic transducer; and
a control module integrated on the IC substrate and configured to control the operation of at least one of the electro-optic transducer driver and the post-amplifier,
wherein the optoelectronic transducer substrate, the electro-optic transducer substrate, the post-amplifier, the electro-optic transducer driver, and the control module are integrated together and the optoelectronic transducer substrate is a separate substrate from the electro-optic transducer substrate, and the optical transceiver IC is devoid of a printed circuit board (PCB).
2. The optical transceiver IC in accordance with claim 1, each cell further comprising:
one or more optical receive ports directly mounted onto the optoelectronic transducer, wherein the one or more optical receive ports are configured as a physical interface with one or more optical fibers configured to transmit optical signals to the optoelectronic transducer; and
one or more optical transmit ports directly mounted onto the electro-optic transducer, wherein the one or more optical transmit ports are configured as a physical interface with one or more optical fibers configured to transmit optical signals from the electro-optic transducer.
3. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a transimpedance amplifier (TIA) configured for communication with the post-amplifier, wherein the TIA of each cell is integrated on the IC substrate and does not use a PCB for interconnection with the post-amplifier.
4. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a sense photo-diode configured for communication with the control module, wherein the sense photo-diode of each cell is integrated on the IC substrate and does not use a PCB for interconnection with the control module.
5. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a TIA on the optoelectronic transducer substrate and coupled to the optoelectronic transducer, the TIA further being coupled to the post-amplifier,
wherein the optoelectronic transducer and the TIA of each cell do not use a PCB for interconnections with other components in the cell.
6. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a sense photodiode on the electro-optic transducer substrate and coupled to the electro-optic transducer,
wherein the electro-optic transducer and the sense photodiode of each cell do not use a PCB for interconnections with other components in the cell.
7. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a sense photodiode coupled to the electro-optic transducer driver,
wherein the sense photodiode of each cell is integrated on the IC substrate without the use of a PCB for interconnection between components of the cell.
8. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a TIA coupled to the post-amplifier and the optoelectronic transducer,
wherein the TIA of each cell is integrated on the IC substrate without the use of a PCB for interconnection between components of the cell.
9. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a TIA coupled to the post-amplifier and the optoelectronic transducer; and
a sense photodiode coupled to the electro-optic transducer;
wherein the TIA and the sense photodiode of each cell are integrated on the IC substrate without the use of a PCB for interconnection between components of the cell.
10. The optical transceiver IC in accordance with claim 1, wherein the optical transceiver IC is configured for parallel processing where each cell of the multiple cells operates at a different data rate.
11. A computing device used in optical communications comprising:
a Transmit Optical SubAssembly (TOSA);
a Receiver Optical SubAssembly (ROSA); and
a control module configured to control the operation of the TOSA and the ROSA;
wherein the TOSA and the ROSA are integrated together on the single integrated circuit (IC) of claim 1 without the use of a printed circuit board (PCB).
12. The computing device in accordance with claim 11, wherein the ROSA includes a post-amplifier that does not use a PCB to interconnect with other components of the computing device.
13. The computing device in accordance with claim 12, wherein the ROSA further includes an optical receiver and a transimpedance amplifier (TIA) coupled to the post-amplifier, optical receiver and TIA not using a PCB to interconnect with other components of the computing device.
14. The computing device in accordance with claim 11, wherein the TOSA includes a laser driver that does not use a PCB to interconnect with other components of the computing device.
15. The computing device in accordance with claim 14, wherein the TOSA further includes an optical transmitter coupled to the laser driver and a sense photodiode coupled to the optical transmitter, the optical transmitter and sense photodiode not using a PCB to interconnect with other components of the computing device.
16. The computing device in accordance with claim 11, wherein the computing device is one of a 1 G laser transceiver, a 2 G laser transceiver, a 4 G laser transceiver, a 8 G laser transceiver, a 10 G laser transceiver, or a laser transceiver suitable for fiber optic links greater than 10 G.
17. The computing device in accordance with claim 11, wherein the computing device is one of a XFP laser transceiver, a SFP laser transceiver, or a SFF laser transceiver.
18. The optical transceiver IC in accordance with claim 1, wherein the electro-optic transducer driver of each cell is direct current coupled to the corresponding electro-optic transducer.
19. The optical transceiver IC in accordance with claim 1, each cell further comprising:
a TIA, the optoelectronic transducer being coupled to the post-amplifier via the TIA; and a sense photo-diode coupled to the electro-optic transducer for monitoring and coupled to at least one of the electro-optic transducer driver and the control module for providing monitoring information,
wherein the TIA and the sense photo-diode of each cell are integrated with other components of the cell without the use of a PCB.
20. The optical transceiver IC in accordance with claim 1, each cell further including electrical interconnections that:
connect the post-amplifier with the optoelectronic transducer,
connect the electro-optic transducer driver with the electro-optic transducer, and
connect the control module with the electro-optic transducer driver and the post-amplifier,
wherein the electrical interconnections are directly integrated onto the IC substrate by one or more semiconductor fabrication processes including at least one of a photo lithography process, an etching process, and a growth process.
21. A multiple cell optical transceiver comprising:
multiple optical transceiver cells optically isolated from each other optical transceiver cell and fabricated one on top of another in a single integrated circuit (IC), each cell including:
a post-amplifier configured for communication with an optoelectronic transducer;
an optoelectronic transducer coupled to the post-amplifier;
an electro-optic transducer driver configured for communication with an electro-optic transducer;
an electro-optic transducer coupled to the electro-optic transducer driver; and
a control module configured to control operation of at least one of the post-amplifier and the electro-optic transducer driver,
wherein the post-amplifier, the optoelectronic transducer, the electro-optic transducer driver, the electro-optic transducer, and the control module are integrated together without the use of a printed circuit board (PCB), and
wherein the optoelectronic transducer of each cell is integrated on an IC substrate on which the cells of the IC are integrated and the electro-optic transducer of each cell is on a separate electro-optic transducer substrate mounted on the IC substrate.
22. The multiple cell optical transceiver in accordance with claim 21, each cell further comprising:
a trans-impendence amplifier (TIA), the optoelectronic transducer being coupled to the TIA and the TIA being coupled to the post-amplifier;
wherein the optoelectronic transducer and the TIA are integrated with the post-amplifier and the control module; and
wherein the optoelectronic transducer and the TIA do not use a PCB for interconnections with other components in the cell and the interconnections between the post-amplifier, the TIA and the optoelectronic transducer of each cell are directly integrated onto the IC.
23. The multiple cell optical transceiver in accordance with claim 21, each cell further comprising:
a sense photo-diode on the electro-optic transducer substrate mounted on the IC substrate, the sense photo-diode being coupled to the electro-optic transducer for monitoring and coupled to at least one of the electro-optic transducer driver and the control module for providing monitoring information.
24. A multiple cell optical transceiver comprising:
multiple optical transceiver cells optically isolated from each other optical transceiver cell and fabricated one on top of another in a single integrated circuit (IC), each cell being optically isolated from each other cell with at least one cell being configured to operate at one bitrate and at least another cell being configured to operate an another, different bitrate, each cell including:
a post-amplifier configured for communication with an optoelectronic transducer;
an optoelectronic transducer coupled to the post-amplifier;
an electro-optic transducer driver configured for communication with an electro-optic transducer;
an electro-optic transducer coupled to the electro-optic transducer driver; and
a control module configured to control operation of at least one of the post-amplifier and the electro-optic transducer driver,
wherein the post-amplifier, the optoelectronic transducer, the electro-optic transducer driver, the electro-optic transducer, and the control module are integrated together without the use of a printed circuit board (PCB), and
wherein the electro-optic transducer of each cell is integrated on an IC substrate on which the cells of the IC are integrated and the optoelectronic transducer of each cell is on a separate optoelectronic transducer substrate mounted on the IC substrate.
25. The multiple cell optical transceiver in accordance with claim 24, each cell further comprising:
a sense photodiode, the electro-optic transducer being coupled to the sense photodiode and the electro-optic transducer driver;
wherein the electro-optic transducer and the sense photodiode are integrated with the electro-optic transducer driver and the control module; and
wherein the electro-optic transducer and the sense photodiode do not use a PCB for interconnections with other components in the cell and the interconnections between the electro-optic transducer driver, the electro-optic transducer, and the sense photodiode are directly integrated onto the IC.
26. The multiple cell optical transceiver in accordance with claim 24, each cell further comprising:
a TIA on the optoelectronic transducer substrate mounted on the IC substrate, the optoelectronic transducer being coupled to the post-amplifier via the TIA.