1460742785-68a8459a-05a5-411d-a466-1fe0a4e5a467

What is claimed is:

1. An underwater building unit, characterized in that:
the underwater building unit includes a caisson with both ends open and is composed of two rows of box boards not being intersected with each other;
each row of box boards consists of a set of stake-plate body combinations and bind members between every two adjacent stake-plate body combinations;
a positioning beam is located on the top of the box boards and connects the two box boards; and
a cross rib is at the middle section of the outer surface of the plate body of each bind member.
2. The underwater building unit according to claim 1, characterized in that:
the said bind members are positioning stake-plate body combinations (1) which are located above the cross rib of the plate body and have outwardly protruded parts, the stake-plate body combination (2) and the positioning stake-plate body combination (1) are mounted facing each other in two rows of box boards respectively;
positioning beam mounting grooves are formed in the middle of the top edge of the plate body of the positioning stake-plate body combination (1), at least a part of the main girder of the positioning beam (3) is embedded into the positioning beam mounting groove; and
the length of the main girder of the positioning beam (3) should be consistent with the distance between the outer surface of the plate bodies of the two opposite positioning stake-plate body combinations (1) of two rows of box boards.
3. The underwater building unit according to claim 2, characterized in that:
a cross rib is provided on the outer surface of the stake-plate body combination (2), is located at the position being consistent with that of the cross rib on the plate body of the positioning stake-plate body combination (1), and is coupled with the outwardly protruded parts of the plate body of the positioning stake-plate body combination (1).
4. The underwater building unit according to claim 1, characterized in that:
the stake-plate body combination (11) in two rows of box boards is mounted in pairs and facing each other, the said bind member is a positioning baffle (12) comprised of a plate body and an outward lug protruded outwardly along the direction of its outer surface on the upper edge of the plate body; and
a groove is provided on the lower surface of the positioning plate body at the two ends of the positioning beam (13) to be coupled with the upper part of the middle stake of the stake-plate body combination (11), the length of the main girder of the positioning beam (13) should be consistent with the distance between the outer edges of the plate bodies of the two opposite positioning stake-plate body combinations (11) of the two rows of box boards.
5. The underwater building unit according to claim 4, characterized in that:
the cross rib on the positioning baffle (12) is composed of at least one cross rib (14) connecting the two vertical ribs (15) at the middle part of the positioning baffle (12).
6. The underwater building unit according to claim 1, 2, 3, 4 or 5, characterized in that:
a wall formed with plate body-plate body combination (7) is provided on the top of the open caisson, the plate body-plate body combination (7) is composed of two plate bodies posed at an angle and the connecting plate body (8) between the two plate bodies, a space is provided between the upper and the lower end surfaces of the plate body-plate body combination (11) and the plate body for the cast-in-place concrete.
7. The underwater building unit according to claim 6, characterized in that:
reinforcing bar through holes (9) are formed on the connecting plate body (8).
8. The underwater building unit according to claim 7, characterized in that:
the upper and the lower end surfaces of the connecting plate body (8) is perpendicular to one of the plate bodies.
9. The underwater building unit according to claim 8, characterized in that:
the connecting plate body (8) is integrally formed as a single unit with one of the plate body, a corresponding mounting hole is formed on the other plate body, pre-buried reinforcing bars (10) are placed inside the hole, and protruded pre-buried reinforcing bars are provided on the end surface on which the connecting plate body (8) is connected with the plate body.
10. The underwater building unit according to claim 6, characterized in that:
a breakwater (6) is provided above the plate body-plate body combination (7).
11. An installation method of the underwater building unit according to any one of claims 1 to 10, characterized in that:
a. locate the insert plate centring frame on water bottom along design direction;
b. put two rows of stake-plate body combination to a predetermined depth according to the position mark of the centring frame above water surface and set in place;
c. hang the positioning frame away;
d. for each row of stake-plate body combination, put positioning stake-plate body combination into the preserved gaps between every two adjacent stake-plate body combinations and make the outwardly protruded positioning part lock the stake-plate body combination and positioned by a cross rib; and
e. locate the no-ear positioning beam in the open groove of the positioning stake-plate body combination.
12. An installation method of the underwater building unit according to any one of claims 1 to 10, characterized in that:
a. locate the insert plate centring frame on water bottom along design direction;
b. put two rows of stake-plate body combination to a predetermined depth according to the position mark of the centring frame above water surface and set in place;
c. hang the insert plate centring frame away;
d. make positioning beam with forked ear buckled on two stake-plate body combinations to make the opening of the positioning beam baffle and the stake of the stake-plate body combinations being lock by each other; and
e. for each row of stake-plate body combination, put the baffle with rib in the space between two adjacent stake-plate body combinations.
13. The installation method of the underwater building unit according to claim 11 or 12, characterized in that:
in case the foundation is too soft, when inserting stake-plate body combination or positioning stake-plate body combination, put the stake into foundation to a predetermined depth first and fill with grit or crushed stone through stake hole, then lift the stake to make the filling material spread into the gap around the tip of the stake and then put the stake back in.
14. An application method of the underwater building unit according to any one of claims 1 to 10, characterized in that:
the construction of the sea entry road is proceeded as follows:
a. put the open caisson into water;
b. make the open caisson full of rubble;
c. add rubble to design height;
d. place mould plate above two rows of structural members of the open caisson; and
e. cast-in-place concrete between mould plates to design height.
15. An application method of the underwater building unit according to any one of claims 1 to 10, characterized in that:
the construction of the artificial island is proceeded as follows:
a. put the open caisson into water and form an annular frame;
b. make the open caisson full of rubble;
c. install the plate body-plate body combination on top of the open caisson;
d. put the trunk reinforcing bar through the reinforcing bar through hole in the plate body-plate body combination and tie up the trunk reinforcing bars with hoops;
e. cast-in-place concrete in the plate body-plate body combination and preserve space for the breakwater;
f. install the breakwater at the preserved space; and
g. fill the inside of the annular wall formed by the plate body-plate body combinations and the breakwater with dry soil until reaching the height of the wall.
16. An application method of the underwater building unit according to any one of claims 1 to 10, characterized in that:
the construction of the seawall is proceeded as follows:
a. put the open caisson into water along design direction;
b. make the open caisson full of rubble;
c. install the plate body-plate body combination on top of the open caisson;
d. put the trunk reinforcing bar through the reinforcing bar through hole on the plate body-plate body combination and tie up the trunk reinforcing bars with hoops;
e. cast-in-place concrete in the plate body-plate body combination and preserve space for the breakwater;
f. install the breakwater at the preserved space; and
g. fill the inside of the downstream face of the wall formed by the plate body-plate body combination and the breakwater with dry soil until reaching the height of the wall body.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

What is claimed is:

1. An isolated polynucleotide comprising a member selected from the group consisting of:
(a) a polynucleotide having at least 95% identity to a polynucleotide encoding a polypeptide comprising an amino acid sequence set forth in FIGS. 1A-F;
(b) a polynucleotide having at least 95% identity to a polynucleotide encoding a polypeptide comprising amino acids 20 to 540 of FIGS. 1A-F;
(c) a polynucleotide having at least 95% identity to a polynucleotide encoding a polypeptide comprising the hECM-1-SV-1 amino acid sequence; and
(d) a polynucleotide which is complementary to the polynucleotide of (a), (b) or (c).
2. The polynucleotide of claim 1 wherein the polynucleotide is DNA.
3. The polynucleotide of claim 1 wherein the polynucleotide is RNA.
4. The polynucleotide of claim 2 encoding a polypeptide comprising amino acids 20 to 540 set forth in FIGS. 1A-F.
5. The polynucleotide of claim 2 comprising nucleotides 139 to 1701 set forth in FIGS. 1A-F.
6. The polynucleotide of claim 2 comprising nucleotides 139 to 1701 but missing nucleotides 812 to 1186 as set forth in FIGS. 1A-F.
7. An isolated polynucleotide comprising a member selected from the group consisting of:
(a) a polynucleotide having at least 95% identity to a polynucleotide encoding the same mature polypeptide expressed by the DNA contained in ATCC Deposit No. 97302; and
(b) a polynucleotide complementary to the polynucleotide of (a).
8. A vector comprising the DNA of claim 2.
9. A host cell comprising the vector of claim 8.
10. A process for producing a polypeptide comprising: expressing from the host cell of claim 9 the polypeptide encoded by said DNA.
11. A process for producing cells capable of expressing a polypeptide comprising genetically engineering cells with the vector of claim 8.
12. A polypeptide comprising a member selected from the group consisting of:
(a) a polypeptide having an amino acid sequence set forth in FIGS. 1A-F;
(b) a polypeptide comprising amino acids 20 to 540 set forth in FIGS. 1A-F;
(c) a polypeptide which is at least 95% identical to the polypeptide of (a); and
(d) a polypeptide which is at least 95% identical to the polypeptide of (b).
13. The polypeptide of claim 12 comprising amino acid 20 to amino acid 540 of FIGS. 1A-F.
14. An antibody against the polypeptide of claim 12.
15. An agonist to the polypeptide of claim 12.
16. An antagonist to the polypeptide of claim 12.
17. A method for the treatment of a patient having need of hECM-1 comprising: administering to the patient a therapeutically effective amount of the polypeptide of claim 12.
18. The method of claim 17 wherein said patient is administered a therapeutically effective amount of the agonist of claim 15.
19. The method of claim 17 wherein said therapeutically effective amount of the polypeptide is administered by providing to the patient DNA encoding said polypeptide and expressing said polypeptide in vivo.
20. A method for the treatment of a patient having need to inhibit hECM-1 comprising: administering to the patient a therapeutically effective amount of the compound of claim 16.
21. A process for identifying compounds active as antagonists to the polypeptide of claim 12 comprising:
contacting a reaction mixture containing a cell type which expresses an hECM-1 receptor and a compound to be screened; and
detecting the absence of a signal generated from said receptor after binding of said compound to identify if the compound is an effective antagonist.
22. A process for diagnosing a disease or a susceptibility to a disease comprising:
determining a mutation in the polynucleotide of claim 1.
23. A diagnostic process comprising:
analyzing for the presence of the polypeptide of claim 12 in a sample derived from host.
24. A method of stimulating angiogenesis in a patient comprising administering to the patient the polypeptide of claim 16.

1460742777-2ee4c4fa-a589-4a66-9e0d-36820ef16824

What is claimed is:

1. An apparatus for continuously manufacturing ingots of low-oxygen copper, comprising:
a melting furnace in which combustion may be performed in a reducing atmosphere so as to produce molten copper;
a soaking furnace connected to receive molten copper supplied from the melting furnace and adapted to maintain a predetermined temperature of the molten copper;
a casting trough connected to receive molten copper supplied from the soaking furnace and configured to seal the molten copper supplied from the soaking furnace in a non-oxidizing atmosphere, and configured for transferring the molten copper to a turn-dish;
a degasser provided in the casting trough and adapted for dehydrogenating the molten copper passing through the casting trough;
a continuous casting machine connected and adapted for continuously producing cast copper from the molten copper supplied from the turn-dish; and
a cutter positioned for cutting the cast copper into a predetermined length.
2. An apparatus for manufacturing ingots of low-oxygen copper, according to claim 1, wherein the degasser comprises a stirrer.
3. An apparatus for manufacturing ingots of low-oxygen copper, according to claim 2, wherein the stirrer comprises dikes positioned to cause a meandering the flow of the molten copper passing through the casting trough.
4. An apparatus for continuously manufacturing a low-oxygen copper wire, comprising:
a melting furnace in which combustion may be performed in a reducing atmosphere so as to produce molten copper;
a soaking furnace connected to receive molten copper supplied from the melting furnace and adapted to maintain a predetermined temperature of the molten copper;
a casting trough connected to receive molten copper supplied from the soaking furnace and configured to seal the molten copper supplied from the soaking furnace in a non-oxidizing atmosphere, and configured for transferring the molten copper to a turn-dish;
a degasser provided in the casting trough and adapted for dehydrogenating the molten copper passing through the casting trough;
a continuous casting machine, including a belt caster, connected and adapted for continuously producing cast copper from the molten copper supplied from the turn-dish; and
a rolling machine positioned for rolling the cast copper so as to produce the low-oxygen copper wire.
5. An apparatus for manufacturing a low-oxygen copper wire, according to claim 4, wherein the degasser comprises a stirrer.
6. An apparatus for manufacturing a low-oxygen copper wire, according to claim 5, wherein the stirrer comprises dikes positioned for causing a meandering the flow of the molten copper passing through the casting trough.
7. An apparatus for continuously manufacturing ingots of low-oxygen copper, comprising:
a melting furnace in which combustion may be performed in a reducing atmosphere so as to produce molten copper;
a soaking furnace connected to receive molten copper supplied from the melting furnace and adapted to maintain a predetermined temperature of the molten copper;
a casting trough connected to receive molten copper supplied from the soaking furnace and configured to seal the molten copper supplied from the soaking furnace in a non-oxidizing atmosphere, and configured for transferring the molten copper to a turn-dish;
a degasser provided in the casting trough and adapted for dehydrogenating the molten copper passing through the casting trough;
an adder positioned for adding silver to the dehydrogenated molten copper;
a continuous casting machine, including a belt caster, connected and adapted for continuously producing cast copper from the molten copper supplied from the turn-dish; and
a rolling machine positioned for rolling the cast copper so as to produce the low-oxygen copper wire.
8. An apparatus for manufacturing a wire composed of a low-oxygen copper alloy, according to claim 7, wherein the degasser comprises a stirrer.
9. An apparatus for manufacturing a wire composed of a low-oxygen copper alloy, according to claim 8, wherein the stirrer comprises dikes positioned for causing a meandering the flow of the molten copper passing through the casting trough.
10. An apparatus for continuously manufacturing ingots of low-oxygen copper, comprising:
a melting furnace in which combustion may be performed in a reducing atmosphere so as to produce molten copper;
a soaking furnace connected to receive molten copper supplied from the melting furnace and adapted to maintain a predetermined temperature of the molten copper;
a casting trough connected to receive molten copper supplied from the soaking furnace and configured to seal the molten copper supplied from the soaking furnace in a non-oxidizing atmosphere, and configured for transferring the molten copper to a turn-dish;
a degasser provided in the casting trough and adapted for dehydrogenating the molten copper passing through the casting trough;
an adder positioned for adding phosphorus to the dehydrogenated molten copper;
a continuous casting machine, including a belt caster, connected and adapted for continuously producing base cast copper from the molten copper supplied from the turn-dish; and
a rolling machine positioned for rolling the base cast copper so as to produce the low-oxygen copper wire.
11. An apparatus for manufacturing a base low-oxygen copper material, according to claim 10, wherein the degasser is a stirrer.
12. An apparatus for manufacturing a base low-oxygen copper material, according to claim 11, wherein the stirrer comprises dikes positioned to cause a meandering the flow of the molten copper passing through the casting trough.
13. An apparatus for manufacturing a base low-oxygen copper material, according to claim 12, further comprising a cutter positioned to cut the base low-oxygen copper material to a predetermined length.
14. An apparatus for manufacturing a base low-oxygen copper material, according to claim 13, further comprising a washing positioned and adapted to wash the base low-oxygen copper material having a predetermined length.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method comprising:
continuously monitoring an audio stream associated with a gesture input stream;
detecting a speech event in the audio stream;
identifying a temporal window associated with a time of the speech event;
analyzing, via a processor, data from the gesture input stream within the temporal window to identify a gesture event; and
processing the speech event and the gesture event to produce a multimodal command.
2. The method of claim 1, wherein a gesture in the gesture input stream is directed to a display, but is remote from the display.
3. The method of claim 1, wherein analyzing the data from the gesture input stream further comprises calculating an average of gesture coordinates within the temporal window.
4. The method of claim 1, wherein processing the speech event and the gesture event further comprises:
identifying a speech command from the speech event;
identifying parameters from the gesture event; and
applying the parameters to the speech command.
5. The method of claim 1, wherein a gesture filtering module focuses the temporal window based on timing of specific words in the speech event.
6. The method of claim 1, further comprising executing the multimodal command.
7. The method of claim 1, wherein at least one of a length and a position of the temporal window is based on a type of the speech event.
8. The method of claim 1, wherein the speech event is detected in the audio stream without an explicit user activation via one of a button press and a touch gesture.
9. The method of claim 1, wherein the gesture input stream comprises input from at least one of a motion detector, a motion capture system, a camera, and an infrared camera.
10. The method of claim 1, wherein the audio stream comprises input from at least one of a microphone and an array of microphones.
11. The method of claim 1, wherein identifying the temporal window comprises modifying the temporal window based on one of the gesture event and any other data to yield a modified temporal window.
12. A system comprising:
a processor;
a memory having stored therein instructions for controlling the processor to perform steps comprising:
monitoring an audio stream associated with a gesture input stream;
detecting a speech event in the audio stream;
identifying a temporal window associated with a time of the speech event;
analyzing, via a processor, data from the gesture input stream within the temporal window to identify a gesture event; and
processing the speech event and the gesture event to produce a multimodal command.
13. The system of claim 12, wherein a gesture in the gesture input stream is directed to a display, but is remote from the display.
14. The system of claim 12, wherein analyzing the data from the gesture input stream further comprises calculating an average of gesture coordinates within the temporal window.
15. The system of claim 12, wherein processing the speech event and the gesture event further comprises:
identifying a speech command from the speech event;
identifying parameters from the gesture event; and
applying the parameters to the speech command.
16. The system of claim 1, wherein a gesture filtering module focuses the temporal window based on timing of specific words in the speech event.
17. A non-transitory computer-readable storage medium having stored therein instructions which, when executed by a computing device, cause the computing device to perform steps comprising:
continuously monitoring an audio stream associated with a gesture input stream;
detecting a speech event in the audio stream;
identifying a temporal window associated with a time of the speech event;
analyzing, via a processor, data from the gesture input stream within the temporal window to identify a gesture event; and
processing the speech event and the gesture event to produce a multimodal command.
18. The non-transitory computer-readable storage medium of claim 17, wherein the speech event is detected in the audio stream without an explicit user activation via one of a button press and a touch gesture.
19. The non-transitory computer-readable storage medium of claim 17, wherein the gesture input stream comprises input from at least one of a motion detector, a motion capture system, a camera, and an infrared camera.
20. The non-transitory computer-readable storage medium of claim 17, wherein the audio stream comprises input from at least one of a microphone and an array of microphones.