Author: claimsbot

1. An insecticide in particular for killing bed bugs comprising:
Isopropyl Alcohol in an amount of from 5.0-99.9% by weight,
Andiroba Oil in an amount of from 0.0001-5.00% by weight,
Orange Oil in an amount of from 0.0001-5.000% by weight,
Neem Oil in an amount of from 0.0001-5.000% by weight,
Citronella Oil in an amount of from 0.0001-5.000% by weight,
Australian Myrtle Oil in an amount of from 0.0001-5.000% by weight,
Nanosphere structures 0.01%-30.000% by weight,
Phenoxyethanol in an amount of from 0.1-2.0% by weight,
Lavandox in an amount of from 0.1%-1.50% by weight, and
Leucojum Aestivum Bulb Extract in an amount of from 0.01-3.0% by weight, wherein each of said percentages are percentages by weight of the insecticide.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method operative in an Internet content delivery network (ICDN) having a set of content servers organized into regions and that provides delivery of Internet content on behalf of participating content providers, wherein the Internet content delivery network is managed by an Internet content delivery network service provider distinct from the participating content providers, comprising:
having the Internet content delivery network service provider establish a set of one or more enterprise CDN regions within a firewall of an enterprise, wherein each enterprise CDN region has one or more surrogate origin servers, wherein the set of one or more enterprise CDN regions are managed by the Internet content delivery network service provider as part of the ICDN, and wherein a given surrogate origin server in an enterprise CDN region is adapted to host both Internet content that has been tagged by at least one participating content provider for delivery over the ICDN and intranet content that has been tagged by the enterprise for delivery over the ICDN;
responsive to a request for given Internet or intranet content originating from an end user within the enterprise, mapping the end user to a preferred enterprise CDN region that is likely to host the given Internet or intranet content;
serving the given Internet or intranet content from the preferred enterprise CDN region; and
responsive to a DNS query or connection request originating from outside the enterprise and associated with a piece of intranet content that has been tagged by the enterprise for delivery over the ICDN, preventing the DNS query or connection request from being processed within a enterprise CDN region to restrict access to the piece of intranet content from the enterprise CDN region.
2. The method as described in claim 1 wherein the set of one or more enterprise CDN regions are managed in part by importing control data from the Internet content delivery network (ICDN) into the enterprise CDN regions to determine how the given Internet content is to be handled on the surrogate origin servers within the enterprise CDN region.
3. The method as described in claim 1 wherein the set of one or more enterprise CDN regions are managed in part by exporting given data from one or more of the enterprise CDN regions to the ICDN, wherein the given data is selected from log, usage and state data.
4. The method as described in claim 1 further including the step of publishing the given intranet content to the enterprise CDN region from a given location in the enterprise.
5. The method as described in claim 1 wherein each enterprise CDN region is identified using a public IP address space.
6. A method operative in an Internet content delivery network (ICDN) having a set of content servers organized into regions and that provides delivery of Internet content on behalf of participating content providers, wherein the Internet content delivery network is managed by an Internet content delivery network service provider distinct from the participating content providers, comprising:
having the Internet content delivery network service provider establish a set of one or more enterprise CDN regions within a firewall of an enterprise, wherein each enterprise CDN region has one or more servers and is identified by a public IP address, wherein the set of one or more enterprise CDN regions are managed by the Internet content delivery network service provider as part of the ICDN, and wherein a given server in an enterprise CDN region is adapted to host both Internet content that has been lagged by at least one participating content provider for delivery over the ICDN and intranet content that has been tagged by the enterprise for delivery over the ICDN;
responsive to a request for given Internet or intranet content originating from an end user within the enterprise, mapping the end user to a preferred enterprise CDN region that is likely to host the given Internet or intranet content;
serving the given Internet or intranet content to the requesting end user; and
responsive to a DNS query or connection request originating from outside the enterprise and associated with a request for a piece of intranet content that has been tagged by the enterprise for delivery over the ICDN, preventing the DNS query or connection request from being processed within an enterprise CDN region to restrict access to the piece of intranet content from the enterprise CDN region.
7. The method as described in claim 6 wherein a given server within an enterprise CDN region is an ICDN-aware ECDN server.
8. A method operative in an Internet content delivery network (ICDN) having a set of surrogate origin servers that provide delivery of Internet content on behalf of participating content providers, wherein the Internet content delivery network is managed by an Internet content delivery network service provider distinct from the participating content providers, comprising:
having the Internet content delivery network service provider locate at least one ICDN-aware server within a firewall of an enterprise, and wherein the at least one ICDN-aware server is managed by the Internet content delivery network service provider as part of the ICDN, and wherein a given ICDN-aware server is adapted to host both Internet content that has been tagged by at least one participating content provider for delivery over the ICDN and intranet content that has been tagged by the enterprise for delivery over the ICDN;
associating the at least one ICDN-aware server with a public IP address irrespective of its location within the enterprise firewall;
responsive to a request for given Internet or intranet content originating from an end user within the enterprise, selectively mapping the end user to the ICDN-aware server to enable the end user to attempt to retrieve the given Internet or intranet content;
serving the given Internet or intranet content from the ICDN-aware server; and
responsive to a DNS query or connection request originating from outside the enterprise and associated wilt a request for a piece of intranet content that has been tagged by the enterprise for delivery over the ICDN, preventing the DNS query or connection request from being processed to restrict access to the piece of intranet content from the ICDN-aware server.

1. An isolated nucleic acid molecule selected from the group consisting of a nucleic acid molecule comprising the sequence shown in FIG. 1, FIG. 7A, FIG. 8A or 11A, a nucleic acid molecule which encodes the amino acid sequence of FIG. 2, FIG. 7B, FIG. 8B or FIG. 11B, or allelic variants of said sequences, and a nucleic acid molecule that hybridizes to one of the foregoing sequences under stringent conditions.
2. The isolated nucleic acid of claim 1, wherein the nucleic acid encodes a voltage gated Na channel that is preferentially expressed in dorsal root ganglia or trigeminal ganglia.
3. The isolated nucleic acid of claim 2, wherein the nucleic acid encodes the human NaN sodium channel.
4. An expression vector comprising the isolated nucleic acid of any of claims 1 to 3, alone or together with appropriate regulatory and expression control elements.
5. A host cell transformed with the expression vector of claim 4.
6. A Na channel encoded by the isolated nucleic acid of any of claims 1 to 3.
7. The Na channel of claim 6, having the amino acid sequence of FIG. 2.
8. A protein molecule having the amino acid sequence of FIG. 2, FIG. 7B, FIG. 8B, FIG. 11B or a peptide fragment thereof.
9. A protein encoded by the isolated nucleic acid of claim 6.
10. A method to identify an agent that modulates the activity of the Na channel of claim 6, comprising the steps of bringing the agent into contact with a cell that expresses the Na channel on its surface and measuring any resultant changes in the sodium current, resultant change in membrane potential or change in intracellular Na.
11. The method of claim 10, wherein the measuring step is accomplished with voltage clamp measurements or measurement of membrane potential.
12. The method of claim 10, wherein the measuring step is accomplished by measuring the level of intracellular sodium.
13. The method of claim 10, wherein the measuring step is accomplished by measuring sodium influx.
14. The method of claim 13, wherein the sodium influx is measured using 22Na or 86Rb.
15. A method to identify an agent that modulates the transcription or translation of mRNA encoding the Na channel of claim 6, comprising the steps of bringing the agent into contact with a cell that expresses the Na channel on its surface and measuring the resultant level of expression of the Na channel.
16. A method to treat pain, paraesthesia andor hyperexcitability phenomena in an animal or human subject by administering an effective amount of an agent capable of altering Na current flow through NaN channels in DRG or trigeminal neurons.
17. A method to treat pain, paraesthesia andor hyperexcitability phenomena in an animal or human subject by administering an effective amount of an agent capable of modulating the transcription or translation of mRNA encoding the Na channel of claim 6.
18. An isolated nucleic acid that is antisense to the nucleic acid of claim 1 and of sufficient length to modulate the expression of NaN channel in a cell containing the mRNA.
19. A scintigraphic method to image the loci of pain generation or provide a measure of the level of pain associated with DRG or trigeminal neuron mediated hyperexcitability in an animal or human subject by administering labeled monoclonal antibodies or other labeled ligands specific for the NaN Na channel.
20. A method to identify tissues, cells and cell types that express the NaN sodium channel, comprising the step of detecting NaN on the cell surface or intracellularly.
21. A method to identify tissues, cells and cell types that express NaN comprising the step of detecting the presence therein of NaN encoding mRNA.
22. A method of producing a transformed cell that expresses an exogenous NaN encoding nucleic acid, comprising the step of transforming the cell with an expression vector comprising the isolated nucleic acid of any of claims 1 to 3, together with appropriate regulatory and expression control elements.
23. An isolated antibody specific for the NaN channel or polypeptide fragment thereof.
24. The isolated antibody of claim 23, wherein the antibody is labeled.
25. A method of producing recombinant NaN protein, comprising the step of culturing the transformed host of claim 5 under conditions in which the NaN sodium channel or protein is expressed, and recovering the NaN protein.
26. A therapeutic composition comprising an effective amount of an agent capable of altering, such as by increasing or decreasing, the rapidly repriming current flow in axotomized, inflamed or otherwise injured DRG neurons.
27. A method to treat acute pain or acute or chronic neuropathic or inflammatory pain and hyperexcitability phenomena in an animal or a human patient by administering the therapeutic composition of claim 26.
28. A method to screen candidate compounds for use in treating pain and hyperexcitability phenomena by testing their ability to upregulate or downregulate the NaN channel mRNA in axotomized, inflamed or otherwise injured DRG neurons.
29. A method of screening for a mutant NaN allele in a nucleic acid sample comprising the step of hybridizing an intronic microsattelite sequence of Example 20 to the sample under conditions of sufficient stringency to produce a clear signal.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A radiographing apparatus which comprises:
an X-ray source which radiates x-rays with a first energy spectrum and x-rays with a second energy spectrum;
an X-ray detector which detects the x-rays with the first energy spectrum and the x-rays with the second energy spectrum transmitted through an object to be examined, and outputs projection data of the first energy spectrum and projection data of the second energy spectrum;
a control device which controls operations of the X-ray source and the X-ray detector;
an image processing device which generates a desired image on the basis of the projection data of the first energy spectrum and the projection data of the second energy spectrum; and
a display device which displays the image,
wherein the image processing device comprises:
an acquisition device which acquires the projection data of the first energy spectrum and the projection data of the second energy spectrum;
a synthetic image generating device which synthesizes a first image on the basis of the projection data of the first energy spectrum and a second image on the basis of the projection data of the second energy spectrum according to a predetermined synthetic condition to generate a synthetic image,
wherein the display device displays the generated synthetic image; and
a correction device which performs correction according to levels of effective energy of the first energy spectrum and effective energy of the second energy spectrum in order to equalize noise of the first image to noise of the second image for the first image based on projection data of the first energy spectrum and the second image based on projection data of the second energy spectrum,
wherein the synthetic image generating device synthesizes the first image and the second image with noise equalized by the correction device.
2. The radiographing apparatus according to claim 1, wherein
the image processing device generates a first reconstructed image by reconstructing projection data of the first energy spectrum, and generates a second reconstructed image by reconstructing projection data of a second energy spectrum, and
the synthetic image generating device synthesizes the first reconstructed image and the second reconstructed image according to the predetermined synthetic condition to generate the synthetic image.
3. The radiographing apparatus according to claim 2, further comprising:
a mixed ratio calculation device which calculates a mixed ratio of the first reconstructed image and the second reconstructed image, wherein
the synthetic image generating device synthesizes the first reconstructed image and the second reconstructed image according to the mixed ratio which the mixed ratio calculation device calculates.
4. The radiographing apparatus according to claim 3, wherein
the mixed ratio calculation device changes the mixed ratio for every pixel in the first reconstructed image and the second reconstructed image or for every first local area set in the first reconstructed image and second local area set in an area equivalent to the first local area in the second reconstructed image according to local physical quantity.
5. The radiographing apparatus according to claim 3, wherein
the mixed ratio calculation device identifies tissue with the same vital function in the first reconstructed image and in the second reconstructed image, and determines a mixed ratio for said tissue on the basis of a first energy difference and a second energy difference, where the first energy difference is an energy difference between an X-ray absorption edge of the tissue and effective energy of the first energy spectrum, and the second energy difference is an energy difference between the X-ray absorption edge of the tissue and effective energy of the second energy spectrum.
6. The radiographing apparatus according to claim 2, wherein
the synthetic image generating device assigns different colors respectively to the first reconstructed image and the second reconstructed image to generate a plurality of monochrome color images, and synthesizes a plurality of monochrome color images to generate a synthetic color image.
7. The radiographing apparatus according to claim 6, wherein the synthetic image generating device uses colors selected from blue, green and red as the different colors.
8. The radiographing apparatus according to claim 6, further comprising:
a mixed ratio calculation device which calculates a mixed ratio of the plurality of monochrome color images, wherein
the synthetic image generating device synthesizes the plurality of monochrome color images according to the calculated mixed ratio.
9. The radiographing apparatus according to claim 1, wherein
the synthetic image generating device synthesizes projection data of the first energy spectrum and projection data of the second energy spectrum according to the predetermined synthetic condition to generate synthetic projection data, and reconstructs the synthesized projection data to generate the synthetic image.
10. The radiographing apparatus according to claim 9, wherein
the synthetic image generating device combines projection data of the first energy spectrum and projection data of the second energy spectrum which correspond to a position of the object to generate combined projection data, and reconstructs the combined projection data to generate the synthetic image.
11. The radiographing apparatus according to claim 1, further comprising:
a correction device which performs correction according to levels of effective energy of the first energy spectrum and effective energy of the second energy spectrum in order to smooth noise of the first image and noise of the second image for the first image based on projection data of the first energy spectrum and the second image based on projection data of the second energy spectrum, wherein
the synthetic image generating device synthesizes the first image and the second image that the noise is smoothed by the correction device.
12. The radiographing apparatus according to claim 11, wherein the correction device is a device which adjusts at least one of image filter size, scanning speed, a tube current, and an X-ray irradiation range during scanning.
13. The radiographing apparatus according to claim 1, wherein
the X-ray source comprises a target which has a plurality of collision surfaces with different collision angles respectively, and an electron ray generation device which makes electron rays collide with the target, and performs variable control of an energy spectrum or effective energy of X-rays radiated from the X-ray source by making electron rays collide with collision surfaces of a target at different collision angles, or with a target which is constructed of a plurality of target members of different material, and performs variable control of an energy spectrum or effective energy of X-rays radiated from the X-ray source by making the electron rays collide with the target with different material.
14. The radiographing apparatus according to claim 1, further comprising:
an X-ray display device which associates (a) least one of a tube voltage applied to the X-ray source, an X-ray tube filter with which the X-ray source is equipped, which filter absorbs a part of X-rays radiated from a target with which electron rays collide, a collision angle of a collision surface with which the electron rays are made to collide, and a target member with which the electron rays are made to collide, and (b) an energy spectrum or effective energy of X-rays radiated from the X-ray source, wherein the display device displays information related to the energy spectrum or effective energy corresponding thereto.
15. The radiographing apparatus according to claim 1, wherein the X-ray detector comprises a plurality of X-ray detectors with respective different sensitivities.
16. A radiographing apparatus which comprises:
an X-ray source which radiates x-rays with a first energy spectrum and x-rays with a second energy spectrum;
an X-ray detector which detects the x-rays with the first energy spectrum and the x-rays with the second energy spectrum transmitted through an object to be examined, and outputs projection data of the first energy spectrum and projection data of the second energy spectrum;
a control device which controls operations of the X-ray source and the X-ray detector;
an image processing device which generates a desired image on the basis of the projection data of the first energy spectrum and the projection data of the second energy spectrum; and
a display device which displays the image,
wherein the image processing device comprises:
an acquisition device which acquires the projection data of the first energy spectrum and the projection data of the second energy spectrum;
a synthetic image generating device which synthesizes a first image on the basis of the projection data of the first energy spectrum and a second image on the basis of the projection data of the second energy spectrum according to a predetermined synthetic condition to generate a synthetic image,
wherein the display device displays the generated synthetic image;
wherein the image processing device generates a first reconstructed image by reconstructing projection data of the first energy spectrum, and a second reconstructed image by reconstructing projection data of a second energy spectrum, and
the synthetic image generating device synthesizes the first reconstructed image and the second reconstructed image according to the predetermined synthetic condition to generate the synthetic image; and
wherein the synthetic image generating device generates a differential synthetic color image by generating an average value image of the first reconstructed image and the second reconstructed image, calculating a first difference image related to a difference between the average value image and the first reconstructed image, and a second difference image related to a difference between the average value image and the second reconstructed image respectively, and assigning different colors to the first difference image and the second difference image respectively, generating a plurality of differential monochrome color images, and synthesizing the plurality of differential monochrome color images.
17. The radiographing apparatus according to claim 16, wherein
the synthetic image generating device generates an average value image of the first reconstructed image and the second reconstructed image, calculates a first difference image related to a difference between the average value image and the first reconstructed image and a second difference image related to a difference between the average value image and the second reconstructed image respectively, and generates an emphasis image containing pixel values related to respective pixels of the difference images having the greatest absolute values.
18. A radiographing apparatus which comprises:
an X-ray source which radiates x-rays with a first energy spectrum and x-rays with a second energy spectrum;
an X-ray detector which detects the x-rays with the first energy spectrum and the x-rays with the second energy spectrum transmitted through an object to be examined, and outputs projection data of the first energy spectrum and projection data of the second energy spectrum;
a control device which controls operations of the X-ray source and the X-ray detector;
an image processing device which generates a desired image on the basis of the projection data of the first energy spectrum and the projection data of the second energy spectrum; and
a display device which displays the image,
wherein the image processing device comprises:
an acquisition device which acquires the projection data of the first energy spectrum and the projection data of the second energy spectrum;
a synthetic image generating device which synthesizes a first image on the basis of the projection data of the first energy spectrum and a second image on the basis of the projection data of the second energy spectrum according to a predetermined synthetic condition to generate a synthetic image,
wherein the display device displays the generated synthetic image; and
an interpolation device which performs interpolation processing on the basis of projection data of the first energy spectrum and projection data of the second energy spectrum, and generates projection data of an energy spectrum different from the first energy spectrum and the second energy spectrum, wherein
the image processing device reconstructs projection data, generated by the interpolation device, to generate a reconstructed image corresponding to the different energy spectrum.
19. An image processing program stored in non-transitory form in a computer-readable medium, said program when executed in a computer causing the carrying out of the following steps:
a reading step of reading projection data of an X-ray with a first energy spectrum and projection data of an X-ray with a second energy spectrum which transmit an object to be examined; and
a synthesizing step of synthesizing a first image on the basis of the projection data of the first energy spectrum, and a second image on the basis of the projection data of the second energy spectrum according to a predetermined synthetic condition, and generating a synthetic image;
a correction step which performs correction according to levels of effective energy of the first energy spectrum and effective energy of the second energy spectrum in order to equalize noise of the first image to noise of the second image for the first image based on projection data of the first energy spectrum and the second image based on projection data of the second energy spectrum,
wherein noise in the synthetic image is equalized by said correction step.
20. The image processing program according to claim 19, wherein
the synthesizing step combines projection data of a first energy spectrum and projection data of the second energy spectrum which correspond to respective positions in the object to generate combined projection data, and reconstructs the combined projection data to generate a synthetic image.