Author: claimsbot

What is claimed is:

1. A thermoplastic polyester comprising at least one moiety having at least 10 sequential units, said sequential units consisting of units selected from units represented by the following formula (1) and units represented by the following formula (2),
10
wherein
each of R1 independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group;
each of R2 independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group;
each of R3 independently represents hydrogen or a substituted or unsubstituted homoalkyl or heteroalkyl group;
each of R4 independently represents a substituted or unsubstituted homoalkyl or heteroalkyl group; and
said moiety having no fewer than 1 unit represented by formula (1) and no fewer than 1 unit represented by formula (2).
2. The thermoplastic polymer of claim 1, wherein: for all units of formula (1), all R1 are identical, all R2 are identical, and all R3 are identical; and independently for all units of formula (2), all R1 are identical, all R2 are identical, and all R3 are identical.
3. The thermoplastic polymer of claim 2, wherein: for all units of formula (1), all R4 are identical; and independently for all units of formula (2), all R4 are identical.
4. The polyester of claim 3, wherein R1, R2, R3, and R4 in formula (1) correspond to R1, R2, R3, and R4 in formula (2).
5. The polyester of claim 4, wherein each R4 comprises an unsaturated group.
6. The polyester of claim 5, wherein each R4 is selected from the groups represented by the following formula (6):
(CH2)rCHCH(CH2)st (6)
wherein
r represents an integer of 0 to 20;
s represents an integer of 0 to 20;
r sat least 2;
and
t represents an integer of 1 to 4.
7. The polyester of claim 4, wherein each R4 comprises a saturated group.
8. The polyester of claim 7, wherein each R4 is selected from the groups represented by the following formulas (4) and (5):
(CH2)q(4)
(CH2)r-A-(CH2)st (5)
wherein
q represents an integer of 1 to 30;
r represents an integer of 0 to 20;
s represents an integer of 0 to 20;
rsat least 1;
t represents an integer of 1 to 4; and
A represents sulfur, oxygen, or carbonyl.
9. The polyester of claim 8, wherein each R4 is a saturated group containing at least 2 carbon atoms.
10. The polyester of claim 9, wherein each R4 comprises a linear, saturated, homoalkyl group of 8 carbon atoms.
11. The polyester of claim 4, wherein at least one of R1, R2, and R3 is substituted with a substituent selected from the group consisting of hydroxyl, cyano, nitro, chloro, bromo, and fluoro.
12. The polyester of claim 4, wherein each of R1, R2, and R3 independently represents hydrogen or a group represented by the following formula (3):
CH3(CH2)a(3)
wherein a represents an integer from 0 to 20.
13. The polyester of claim 12, wherein each of R1, R2, and R3 independently represents hydrogen or a linear, saturated, homoalkyl group of 4 or fewer carbon atoms.
14. The polyester of claim 13, wherein each of R1, R2, and R3 independently represents hydrogen or a linear, saturated, homoalkyl group of 2 or fewer carbon atoms.
15. The polyester of claim 12, wherein all R1, R2, and R3 are identical.
16. The polyester of claim 15, wherein all R1, R2, and R3 represent hydrogen.
17. A process for preparing a hydroxyfunctional, thermoplastic polyester having a weight average molecular weight of at least 5,000 gmol, comprising:
polymerizing an epoxidized fatty acid in the presence of an onium salt and optionally in the presence of a solvent.
18. The process of claim 17, wherein said solvent is an ether, an ether ester, or a hydroxylated ether solvent.
19. The process of claim 18, wherein said solvent is a bis(alkoxyalkyl)ether solvent, with alk and alkyl representing alkyl groups comprising two or fewer carbon atoms.
20. The process of claim 19, wherein said bis(alkoxyalkyl)ether is a bis(methoxyalkyl) ether.
21. The process of claim 20, wherein said bis(methoxyalkyl)ether is diglyme.
22. The process of claim 17, wherein said onium salt is an alkyl-onium or alkyl-aryl-onium salt, with alkyl representing alkyl groups comprising eight or fewer carbon atoms.
23. The process of claim 22, wherein said onium salt is an ammonium salt.
24. The process of claim 23, wherein said ammonium salt is a tetraalkyl-ammonium salt.
25. The process of claim 24, wherein said tetraalkyl-ammonium salt is a tetraalkyl-ammonium halide.
26. The process of claim 25, wherein said onium salt is tetrabutylammonium bromide.
27. The process of claim 17, wherein said onium salt is a phosphonium salt.
28. The process of claim 27, wherein said phosphonium salt is a monoalkyl-triaryl-phosphonium salt.
29. The process of claim 28, wherein said monoalkyl-triaryl-phosphonium salt is a monoalkyl-triaryl-phosphonium halide.
30. The process of claim 29, wherein said monoalkyl-triaryl-phosphonium halide is ethyltriphenylphosphonium bromide.
31. A polyester obtainable by the process of claim 17.
32. A process for preparing the polyester of claim 1, comprising polymerizing an epoxidized fatty acid in the presence of an onium salt.
33. The process of claim 32, wherein said epoxidized fatty acid is an omega-epoxy fatty acid.
34. The process of claim 33, wherein said omega-epoxy fatty acid is 10,11-epoxyundecanoic acid.
35. A composition made from or using the polyester of claim 4.
36. The composition of claim 35, wherein said composition is a blend comprising:
(i) the polyester of claim 4; and
(ii) at least one further thermoplastic polymer.
37. The blend of claim 36, wherein said at least one further thermoplastic polymer includes a polymer selected from the group consisting of polyethyleneterephthalate, polyethylene, polypropylene, and thermoplastic starch.
38. An article comprising the polyester of claim 4.
39. An article comprising the blend of claim 36.
40. The article of claim 38, wherein said article is a coating, a film, a laminate, a foam, a fiber, an adhesive, a molded part, a cast part, an extruded part, a melt-formed part; a composite, a conglomerate, a blend; a mass, a slab, a sheet, a fabric, a particle, a powder, a solution, a suspension, a dispersion, a colloid, a gel; a container; a pre-container; a bonded article; a heat-sealed or radiofrequency-sealed or vibrational welding-sealed article; or a heat-sealable or radiofrequency-sealable or vibrational welding-sealable article.
41. A process for adhering a first area of a first article to a second area of a second article, at least one of said first area and said second area comprising the polyester of claim 4, said process comprising:
(i) bringing said first area into contact with said second area; and subsequently
(ii) applying energy in the 100 kHz-1500 MHz radio frequency range to said first area and said second area.
42. The process of claim 41, wherein said first article is said second article.
43. An article obtainable with the process of claim 41.
44. The article of claim 43, wherein said article is a sealed bag or a sealed pouch.
45. The composition of claim 35, wherein said composition is a composite comprising the polyester of claim 4.
46. The composite of claim 45, comprising a fiber selected from the group of glass-, carbon-, polyamide-, polyester-, and natural fibers.
47. The composite of claim 45, comprising a natural fibrous material.
48. The composite of claim 47, wherein said material is wood, jute, ramie, flax, bamboo, or sisal.
49. The composite of claim 45, comprising an inert filler.
50. The composite of claim 49, wherein said inert filler is selected from the group consisting of inorganic fillers, polysaccharides, modified polysaccharides, and naturally occurring particulate fillers.
51. The polyester according to claim 1, wherein said polyester is derived from a plant oil.
52. The composition according to claim 35, wherein said polyester is derived from a plant oil.
53. The article according to any one of claims 38-40 and 43-44, wherein said polyester is derived from a plant oil.
54. Use of a polyester according to any one of claims 1-16 and 51 in a method for preparing a composition or article.
55. The use according to claim 54, wherein said article is a coating, a film, a laminate, a foam, a fiber, an adhesive, a molded part, a cast part, an extruded part, a melt-formed part; a composite, a conglomerate, a blend; a mass, a slab, a sheet, a fabric, a particle, a powder, a solution, a suspension, a dispersion, a colloid, a gel; a container; a pre-container; a bonded article; a heat-sealed or radiofrequency-sealed or vibrational welding-sealed article; or a heat-sealable or radiofrequency-sealable or vibrational welding-sealable article.
56. Use of a composition according to any one of claims 35-37, 45-50, and 52 in a method for preparing an article.
57. The use according to claim 56, wherein said article is a coating, a film, a laminate, a foam, a fiber, an adhesive, a molded part, a cast part, an extruded part, a melt-formed part; a composite, a conglomerate, a blend; a mass, a slab, a sheet, a fabric, a particle, a powder, a solution, a suspension, a dispersion, a colloid, a gel; a container; a pre-container; a bonded article; a heat-sealed or radiofrequency-sealed or vibrational welding-sealed article; or a heat-sealable or radiofrequency-sealable or vibrational welding-sealable article.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

What we claim is:

1. An advanced intelligent network telecommunication system comprising:
(a) at least one service switching point;
(b) a service control point comprising a database containing service interaction rules for providing multiple services per trigger to a subscriber, the subscriber having a telephone line connecting the subscriber’s telephone to at least one service switching point;
(c) a trigger with a translation type provisioned on the subscriber’s telephone line at the service switching point;
(d) a first feature service logic program on the service control point;
(e) a second feature service logic program on the service control point; and
(f) a feature interaction manager service logic program, located on the service control point,
wherein when said trigger prompts said at least one service switching point to send a query containing said translation type to the service control point, said feature interaction manager service logic program is invoked and in turn subsequently invokes at least one of said first feature service logic program and said second feature service logic program, according to said service interaction rules in the database.
2. The advanced intelligent network telecommunication system of claim 1, further comprising a signal transfer point located between the service switching point and the service control point, wherein the signal transfer point has the capability of supplementing a query from the service switching point with a subsystem number identifying said feature interaction manager service logic program.
3. The advanced intelligent network telecommunication system of claim 1, wherein said trigger is a termination attempt trigger.
4. The advanced intelligent network telecommunication system of claim 1, further comprising a second service control point, wherein at least one additional feature service logic program is installed on said second service control point.
5. The advanced intelligent network telecommunication system of claim 1, wherein the first and the second feature service logic programs are two services selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
6. The advanced intelligent network telecommunication system of claim 4, wherein said feature interaction manager service logic program invokes said at least one additional feature service logic program via SS7 network according to said rules in the database.
7. The advanced intelligent network telecommunication system of claim 6, wherein the first, the second, and said at least one additional feature service logic programs are selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
8. A method for providing multiple services per trigger to a telephone line subscriber of an advanced intelligent network telecommunication system having a telephone line, a service switching point, a service control point, and a database, comprising the steps of:
(a) provisioning a trigger with a translation type on the subscriber’s telephone line at the service switching point;
(b) providing a first feature service logic program on the service control point;
(c) providing a second feature service logic program on the service control point;
(d) specifying in the database the service interaction rules of priority for invoking at least one of the first feature service logic program and the second feature service logic program; and
(e) providing a feature interaction manager service logic program on the service control point,
wherein when said trigger prompts said service switching point to send a query to the service control point,
the feature interaction manager service logic program is invoked such that it subsequently invokes at least one of the first feature service logic program and the second feature service logic program as specified in the service interaction rules.
9. The method of claim 8, further comprising a signal transfer point located between the service switching point and the service control point, wherein the signal transfer point supplements the query from the service switching point with a subsystem number identifying said feature interaction manager service logic program.
10. The method of claim 8, wherein said trigger is a termination attempt trigger.
11. The method of claim 8, wherein said advanced intelligent network has a second service control point, the method further comprising the step of providing at least one additional feature service logic program on said second service control point.
12. The method of claim 8, wherein the first and the second feature service logic programs are two services selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
13. The method of claim 11, wherein said feature interaction manager service logic program invokes said at least one additional feature service logic program via SS7 network according to said rules in the database.
14. The method of claim 13, wherein the first, the second, and said at least one additional feature service logic programs are selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
15. The method of claim 13, wherein the feature interaction manager service logic program is invoked such that it subsequently invokes at least one of the first and the second feature service logic programs on the first service control point and said at least one additional feature service logic program on said second service control point as specified in the service interaction rules.
16. A service control point for providing multiple services per trigger to a telephone line subscriber of an advanced intelligent network telecommunication system having a telephone line, a service switching point, and a trigger with a specific translation type on the subscriber’s telephone line at the service switching point, said service control point comprising:
(a) a plurality of feature service logic programs each of which has a unique subsystem number;
(b) a feature interaction manager service logic program having its own unique subsystem number;
(c) a database comprising service interaction rules for invoking one or more of said plurality of feature service logic programs;
wherein when the service control point receives a query with said feature interaction manager service logic program’s unique subsystem number, said feature interaction manager service logic program routes said query to one or more of said plurality of feature service logic programs according to said service interaction rules.
17. The service control point of claim 16, further comprising a signal transfer point located between the service switching point and the service control point, wherein the signal transfer point supplements an initial query received from the service switching point with said feature interaction manager service logic program’s own unique subsystem number.
18. The service control point of claim 16, wherein said trigger is a termination attempt trigger.
19. A method for managing a plurality of feature service logic programs through a feature interaction manager located on a service control point, comprising the steps of:
(a) provisioning a trigger on a subscriber’s line at a service switching point;
(b) receiving a query from the service switching point at the service control point;
(c) in response to the query, consulting a database containing service interaction rules regarding how the services are to be invoked; and
(d) using the feature interaction service manager to manage the plurality of feature service logic programs according to said rules.
20. The method of claim 19, further comprising the step of providing a signal transfer point located between the service switching point and the service control point, wherein the signal transfer point supplements an initial query received from the service switching point with a subsystem number identifying said feature interaction manager service logic program.
21. The method of claim 19, wherein at least one of said plurality of feature service logic programs is installed on a first service control point and at least a second one of said plurality of feature service logic programs is installed on a second service control point.
22. The method of claim 21, wherein said feature interaction manager is invoked such that said feature interaction manager subsequently invokes at least one of said plurality of feature service logic programs located on said first service control point and said at least one of said plurality of feature service logic programs installed on said second service control point, according to said service interaction rules in the database.
23. The method of claim 19, wherein said trigger is a termination attempt trigger having a translation type to invoke said feature interaction manager service logic program.
24. A method for managing multiple services of an advanced intelligent network telecommunication system having a telephone line, a service switching point, a signal transfer point, and a service control point comprising the steps of:
(a) installing a feature interaction manager service logic program on the service control point;
(b) installing a first feature service logic program and a second feature service logic program on the service control point;
(c) installing on the service control point service interaction rules for invoking said first feature service logic program and said second feature service logic program;
(d) assigning a first subsystem number to the feature interaction manager service logic program;
(e) assigning a second subsystem number to the first feature service logic program package and a third subsystem number to the second feature service logic program package;
(f) provisioning a trigger on the subscriber’s line at the service switching point;
(g) assigning a unique translation type to the trigger on the subscriber’s line;
(h) upon receiving a query at the signal transfer point from the service switching point containing the unique translation type, supplementing said query with the first subsystem number and sending said supplemented query to the service control point;
(i) upon receiving said supplemented query at the service control point containing the first subsystem number, invoking the feature interaction manager service logic program; and
(j) managing, in the feature interaction manager, said first and second feature service logic programs according to said service interaction rules.
25. The method of claim 24, wherein said trigger is a termination attempt trigger.
26. The method of claim 24, wherein the first and the second feature service logic programs are two services selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
27. The method of claim 24, further comprising the step of installing a second service control point, wherein at least one additional feature service logic program is installed on said second service control point.
28. The method of claim 27, wherein said feature interaction manager service logic program is invoked such that it subsequently invokes at least one of the first feature service logic program, the second feature service logic program, and said at least one additional feature service logic program, according to said service interaction rules in the database.
29. The method of claim 24, further comprising the step of installing a second service control point having at least one additional feature service logic program, wherein said feature interaction manager service logic program invokes said at least one additional feature service logic program via SS7 network according to said service interaction rules in the database.
30. The method of claim 29, wherein the first, the second, and said at least one additional feature service logic programs are selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
31. The method of claim 29, wherein the feature interaction manager service logic program is invoked such that it subsequently invokes at least one of the first and the second feature service packaging applications on the first service control point and said at least one additional feature service logic program on said second service control point as specified in the service interaction rules.
32. The method of claim 24, wherein said feature interaction manager service logic program returns a default response to the service switching point as specified in the service interaction rules when none of said first and second feature service logic programs has been activated.
33. The method of claim 32, wherein said default response is an instruction authorizing call termination.
34. An advanced intelligent network telecommunication system comprising:
(a) a telephone line;
(b) a service switching point that is connected to the telephone line;
(c) a trigger having a unique translation type provisioned on the subscriber’s line at the service switching point;
(d) a service control point in communication with the service switching point;
(e) a feature interaction manager service logic program installed on the service control point having a first subsystem number;
(f) a first feature service logic program having a second subsystem number and a second feature service logic program having a third subsystem number; and
(g) means for managing said first feature service logic program and said first feature service logic program according to a set of service interaction rules.
35. The advanced intelligent network telecommunication system of claim 34, further comprising a signal transfer point located between the service switching point and the service control point, wherein the signal transfer point supplements an initial query received from the service switching point with said first subsystem number.
36. The advanced intelligent network telecommunication system of claim 34, wherein said trigger is a termination attempt trigger.
37. The advanced intelligent network telecommunication system of claim 34, wherein the first and the second feature service logic programs are two services selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
38. The advanced intelligent network telecommunication system of claim 34, further comprising a second service control point, wherein at least one additional feature service logic program is installed on said second service control point.
39. The advanced intelligent network telecommunication system of claim 38, wherein said feature interaction manager service logic program is invoked such that it subsequently invokes at least one of the first feature service logic program, the second feature service logic program, and said at least one additional feature service logic program according to said service interaction rules in the database.
40. The advanced intelligent network telecommunication system of claim 39, wherein the first, the second, and said at least one additional feature service logic programs are services selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
41. The advanced intelligent network telecommunication system of claim 34, further comprising a second service control point having at least one additional feature service logic program, wherein said feature interaction manager service logic program invokes said at least one additional feature service logic program via SS7 network according to said service interaction rules in the database.
42. The advanced intelligent network telecommunication system of claim 41, wherein the first, the second, and said at least one additional feature service logic programs are selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
43. A method for managing multiple services of an advanced intelligent network telecommunication system having a telephone line, a service switching point, and a signal transfer point, comprising the steps of:
(a) installing a feature interaction manager service logic program on a first service control point;
(b) installing a first feature service logic program on said first service control point;
(c) installing a second feature service logic program on a second service control point;
(d) installing on said first service control point service interaction rules for invoking said first feature service logic program and said second feature service logic program;
(e) assigning a first subsystem number to the feature interaction manager service logic program;
(f) assigning a first unique subsystem number to the first feature service logic program package and a second unique subsystem number to the second feature service logic program package;
(g) provisioning a trigger on the subscriber’s line at the service switching point;
(h) assigning a unique translation type to the trigger on the subscriber’s line;
(i) upon receiving a query at the signal transfer point from the service switching point containing the unique translation type, supplementing said query with the first subsystem number and sending said supplemented query to said first service control point;
(j) upon receiving said supplemented query at said first service control point containing the first subsystem number, invoking the feature interaction manager service logic program; and
(k) managing, in the feature interaction manager, said first and second feature service logic programs according to said service interaction rules.
44. The method of claim 43, wherein said trigger is a termination attempt trigger.
45. The method of claim 43, wherein the first and the second feature service logic programs are selected from the group consisting of flexible call forwarding, Internet call waiting, privacy director, advanced intelligent messaging, and simultaneous ringing.
46. The method of claim 43, wherein said feature interaction manager service logic program returns a default response to the service switching point as specified in the service interaction rules when none of said first and second feature service logic programs has been activated.
47. The method of claim 46, wherein said default response is an instruction authorizing call termination.
48. An advanced intelligent network telecommunication system comprising:
(a) at least one service switching point;
(b) a first service control point comprising a database containing service interaction rules for providing multiple services per trigger to a subscriber, the subscriber having a telephone line connecting the subscriber’s telephone to at least one service switching point;
(c) a trigger with a translation type provisioned on the subscriber’s telephone line at the service switching point;
(d) a feature interaction manager service logic program, located on the first service control point;
(e) a first feature service logic program on a second service control point; and
(f) a second feature service logic program on one of a third service control point and the second service control point,
wherein when said trigger prompts said at least one service switching point to send a query containing said translation type to the first service control point, said feature interaction manager service logic program is invoked and in turn subsequently invokes at least one of said first feature service logic program and said second feature service logic program, according to said service interaction rules in the database.

1. A method for calibrating antimicrobic susceptibility testing data of microorganisms, wherein the method comprises the steps of
creating a histogram based on in vitro susceptibility test data against an antimicrobial agent for isolates from a microbial species, which microbial species isolates may contain unknown resistant strains against said antimicrobial agent wherein the number of isolates of microbial species or percentage of the total number of isolates of microbial species is on a y-axis of said histogram and registered response values against said antimicrobial agent on a x-axis of said histogram;
determining a position of a response peak of the histogram between a high response side and a low response side corresponding to isolates of microbial species susceptible to said antimicrobial agent;
calculating from said high response side of said histogram at least one statistical parameter; and
defining a limit for susceptibility interpretation and comparative analysis of antimicrobic resistance, which is based on said at least one statistical parameter; said limit separating susceptible strains from resistant strains against said antimicrobial agent.
2. Method as in claim 1, wherein said isolates arc clinical isolates.
3. Method as in claim 1, wherein said at least one statistical parameter is statistically obtained from a probability distribution calculated from said high response side of said histogram.
4. Method as in claim 1, wherein said microbial species is a bacterial species or a fungal species.
5. Method as in claim 1, wherein said antimicrobial agent is an antibiotic.
6. Method as in claim 1, wherein said antimicrobic susceptibility testing is a Minimal Inhibitory Concentration test, said registered response values being minimal inhibitory concentrations.
7. Method as in claim 1, wherein said antimicrobic susceptibility testing is a disk diffusion test, said registered response values being inhibition zone diameter values from paper disks impregnated with said antimicrobial agent.
8. Method as in claim 3, wherein said probability distribution is a Gaussian distribution.
9. Method as in claim 8, wherein said at least one statistical parameter is the mean, defining a position of the statistical response peak between a high statistical response distribution side and a low statistical response distribution side, andor standard deviation.
10. Method as in claim 9. wherein said limit is defined as three times said standard deviation below said mean.
11. Method as in claim 9, wherein said Gaussian distribution is a standard Gaussian distribution.
12. Method as in claim 9, wherein said Gaussian distribution is a normalized Gaussian distribution of a theoretical normal population.
13. Method as in claim 12, wherein said normalized Gaussian distribution is construed from said position of said statistical response peak, said high statistical response distribution side, and its mirror image.
14. Method as in claim 12, wherein a total number for said theoretical normal population is construed by a procedure comprising the steps of
calculating a slope for a line through said number of isolates of adjacent registered response values starting on said high response distribution side;
detecting a shift in slope direction, which represents the position of said statistical response peak, thereby defining said mean; and
calculating said total number as the doubled sum of half the number of isolates at said position plus the number of isolates having higher response values.
15. Method as in claim 13, wherein said normalized Gaussian distribution is construed graphically.
16. Method as in claim 14, wherein said normalized Gaussian distribution is determined by a procedure comprising the steps of
calculating for each registered response value a percentage value as percent of said total number;
calculating accumulated percentage values for each of said number of isolates or percent isolates on said statistical high response distribution side;
performing a linearized transformation of said accumulated percentage values against said statistical response values; and
calculating the equation constants for a linear relationship obtained from said transformation; thereby defining said normalized Gaussian distribution of said theoretical normal population.
17. Method as in claim 15, wherein said graphical construction is performed by means of an undirected graphical model or a directed graphical model.
18. Method as in claim 16, wherein said calculation of equation constants is performed by means of the least squares method.
19. Method as in claim 16, wherein said calculation of accumulated percentage values is performed in the direction 100% to 0%.
20. Method as in claim 16, wherein said transformation k a probit transformation.
21. Method as in claim 20, wherein said standard deviation is calculated from said probit transformation.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. At least one compound of the Formula I:
a pharmaceutically acceptable salt thereof, a solvate thereof, a chelate thereof, a non-covalent complex thereof, a prodrug thereof, and mixtures of any of the foregoing, wherein:
n is 1 to 6;
R1 is chosen from H, lower alkyl and substituted lower alkyl;
R2 is chosen from H, lower alkyl and substituted lower alkyl;
R3 and R4 are independently chosen from H, lower alkyl, substituted lower alkyl, lower haloalkyl, substituted lower haloalkyl, or R3 and R4 can join together to form a 3 to 6 membered ring or a substituted 3 to 6 membered ring;
R5 is chosen from OH, SH, NH2, lower alkyl, substituted lower alkyl, lower alkoxy, substituted lower alkoxy and sulfanyl;
R6 is chosen from H, OH, SH NH2, NHSO2R1 and sulfonyl;
each of R7, R8, R9 and R10 is independently chosen from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, NR3R4, C(O)OH, OR13, SR13, SO2R13, CN, NO2, halo, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkylsilyl, substituted alkylsilyl, alkynylsilyl, substituted alkynylsilyl, alkoxy, substituted alkoxy, alkoxycarbonyl, substituted alkoxycarbonyl, and \u2014X\u2014R12, wherein:
R3 and R4 are defined above;
X is chosen from \u2014N(R11)\u2014Y\u2014 and \u2014Y\u2014N(R11)\u2014;
Y is chosen from C(O), SO2, alkylene, substituted alkylene, alkenylene, substituted alkenylene, alkynylene, and substituted alkynylene;
R11 is chosen from H, lower alkyl, and substituted lower alkyl,
R12 is chosen from H, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; and
R13 is chosen from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl; alkynyl, substituted alkynyl and NR3R4;
wherein optionally at least one of adjacent pairs R6 and R7, R7 and R8, R8 and R9, R9 and R10, and R10 and R1, join together to form a 4 to 7 membered ring or a substituted 4 to 7 membered ring.
2. The at least one compound according to claim 1, wherein R3 and R4 join together to form a 3 to 6 membered ring or a substituted 3 to 6 membered ring.
3. The at least one compound according to claim 2, wherein the 3 to 6 membered ring or the substituted 3 to 6 membered ring comprises at least one heteroatom.
4. The at least one compound according to claim 2, wherein the 3 to 6 membered ring or the substituted 3 to 6 membered ring comprises at least two heteroatoms.
5. The at least one compound according to claim 1, wherein R6 and R7 join together to form a 4 to 7 membered ring or a substituted 4 to 7 membered ring.
6. The at least one compound according to claim 5, wherein the 4 to 7 membered ring or the substituted 4 to 7 membered ring comprises at least one heteroatom.
7. The at least one compound according to claim 5 wherein the 4 to 7 membered ring or the substituted 4 to 7 membered ring comprises at least two heteroatoms.
8. The at least one compound according to claim 5 wherein the 4 to 7 membered ring or the substituted 4 to 7 membered ring comprises at least three heteroatoms.
9. The at least one compound according to claim 1, wherein at least one of R7, R8, R9 and R10 is independently chosen from halo and a moiety substituted with at least one halo.
10. The at least one compound according to claim 1, wherein at least one of R7, R8, R9 and R10 is independently chosen from alkoxy or substituted alkoxy.
11. The at least one compound according to claim 1, wherein at least one of R7, R8, R9 and R10 is independently chosen from alkylsilyl, substituted alkylsilyl, alkynylsilyl, and substituted alkynylsilyl.
12. The at least one compound according to claim 1, wherein at least one of R7, R8, R9 and R10 is independently chosen from aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, and substituted heterocycloalkyl.
13. The at least one compound according to claim 1, wherein at least one of R7, R8, R9 and R10 is independently chosen from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, and substituted alkynyl.
14. The at least one compound according to claim 1 having the structure of any one of Compounds 1-175 set forth in Table 1.
15. A pharmaceutical composition comprising at least one pharmaceutically acceptable excipient, and a therapeutically effective amount of at least one compound according to claim 1.
16. The pharmaceutical composition of claim 15, wherein the at least one compound is present in an amount effective for the treatment of at least one disease chosen from ischemia, anemia, wound healing, auto-transplantation, allo-transplantation, xeno-transplantation, systemic high blood pressure, thalassemia, diabetes, cancer and an inflammatory disorder.
17. A method of increasing HIF levels or activity in a subject administering to the subject at least one compound according to claim 1.
18. A method of treating a condition where it is desired to modulate HIF activity comprising administering to a subject at least one compound according to claim 1.
19. A method according to claim 18, wherein said condition is chosen from at least one of ischemia, anemia, wound healing, auto-transplantation, allo-transplantation, xeno-transplantation, systemic high blood pressure, thalassemia, diabetes, cancer and an inflammatory disorder.
20. A method of treating a hypoxic or ischemic related disorder in a subject comprising administering to a subject at least one compound according to claim 1.
21. A method of modulating the amount of HIF in a cell comprising contacting the cell with at least one compound according to claim 1.
22. A method of increasing the amount of hemoglobin F in a subject comprising administering to the subject at least one compound according to claim 1.
23. A method of modulating angiogenesis in a subject comprising administering to the subject at least one compound according to claim 1.
24. A method of treating at least one disease in a patient in need of such treatment comprising administering to the patient a therapeutically effective amount of at least one compound according to claim 1.
25. The method according to claim 24, wherein the at least one disease is chosen from ischemia, anemia, wound healing, auto-transplantation, allo-transplantation, xeno-transplantation, systemic high blood pressure, thalassemia, diabetes, cancer and an inflammatory disorder.
26. A method of inhibiting HIF hydroxylation in a subject comprising administering to the subject at least one compound according to claim 1.
27. The at least one compound according to claim 1, wherein the HIF PHD inhibitory activity IC50 value is 40 \u03bcM or less.
28. The at least one compound according to claim 1, wherein the HIF PHD inhibitory activity IC50 value is 1.0 \u03bcM or less.
29. An assay for the detection of HIF1\u03b1 hydroxyproline residues comprising:
a) incubating a fluorochrome-labeled HIF1\u03b1 polypeptide or fragment thereof with a VCB complex labeled with a rare earth element;
b) detecting the binding of the VCB complex to HIF1\u03b1 by homogeneous time-resolved FRET.
30. The assay according to claim 29, wherein the fluorochrome is allophycocyanin.
31. The assay according to claim 29, wherein the rare earth element is europium.
32. An assay for the detection of HIF1\u03b1 hydroxyproline residues comprising:
a) incubating a HIF1\u03b1 polypeptide or fragment thereof with a VCB complex labeled with ruthenium;
b) detecting the binding of the VCB complex to HIF1\u03b1 by electrochemiluminescence.
33. The assay according to claim 32, wherein the HIF1\u03b1 polypeptide or fragment thereof is bound to a solid support.