Author: claimsbot

1. A method of manufacturing a composite wood adhesive comprising:
providing an amylaceous material consisting essentially of starch or flour that is uncooked comprising less than about 25% moisture;
providing about 5-60% of a high fiber by-product;
mixing the amylaceous material and the high fiber by-product;
co-extruding the high fiber by-product with the amylaceous material at a temperature of about 150 F to about 400 F, at a die pressure of about 50 PSI to about 2000 PSI, and at a rate of about 100 RPM to about 600 RPM, such that the amylaceous material comprises about 25-35% of fully or partially pre-gelatinized starch or flour and about 65-75% of substantially uncooked starch or flour to form a secondary extender;
providing about 60-80% of at least one resin, about 3-10% of a primary extender comprising walnut shell, pecan shell, alder bark, coconut shell or the fibrous dry substance remaining after furfural production, about 12-18% added water and about 1-5% of at least one caustic; and
mixing the secondary extender, the at least one resin, the primary extender, the water and the at least one caustic to form the composite wood adhesive.
2. The method of claim 1, wherein the amylaceous material comprises corn flour and the high fiber by-product comprises soy hull.
3. The method of claim 1, wherein the high fiber by-product is chosen from the group consisting of soybean hull, corn hull, wheat hull, oat hull, sorghum hull, cotton seed hull, malt husks, extracted corn germ, rice hull, rice bran, spent distillers grain, spent brewers grain, spent solids from cellulosic fermentation or mixtures thereof.
4. The method of claim 1, wherein the resin is phenol-formaldehyde.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method of forming an MRI system having an associated imaging volume and main field generating coils of an MRI magnet that generate a magnetic field within the imaging volume, comprising:
forming at least one winding of the main field generating coils with high temperature superconducting material;
positioning the winding in a heat station for receiving cryogenic cooling in order to depress the winding temperature and place the winding material in a superconducting state when generating the main field; and
positioning a gradient coil between the imaging volume and the winding without placing a thermal radiation shield structure between the gradient coil and the winding.
2. The method of claim 1 wherein the winding is capable of sustaining a critical current density of at least 100 Amps per square cm at a temperature of 20 K.
3. The method of claim 1 further comprising the step of forming the high temperature superconductor material with at least Magnesium and Boron.
4. The method of claim 3 wherein the step of forming the high temperature superconductor material further comprises adding nano-particles selected from the group consisting of binary, ternary or complex oxides, carbides, borides, andor nitrides.
5. The method of claim 4 wherein the nano-particles comprise SiC.
6. The method of claim 3 wherein the high temperature superconductor material comprises MgB2.
7. The method of claim 1 further comprising the step of forming a thermal reservoir within a portion of the heat station for receiving cryogenic fluid.
8. The method of claim 1 including the further step of positioning the heat station within a vacuum vessel, wherein the step of positioning the gradient coil includes placing the gradient coil interior to the vacuum vessel.
9. A method of operating a Magnetic Resonance Imaging (MRI) system having an imaging volume therein, a vacuum vessel positioned about the imaging volume, at least one superconducting main coil positioned within the vacuum vessel for generating a magnetic field within the imaging volume and at least one gradient coil for adjusting the magnetic field within the imaging volume, the method comprising:
providing cryogenic cooling from a cooling device into a portion of the vacuum vessel containing the main coil to cool the main coil to a superconducting state a temperature at or lower than Tc but higher than 20 K;
energizing the main coil while in the superconducting state; and
energizing the gradient coil in the absence of a thermal shield structure between the gradient coil and the main coil.
10. The method of claim 9 wherein the step of energizing the gradient coil is performed with the gradient coil positioned in the vacuum vessel to receive cryogenic cooling thereby rendering the gradient coil in a superconductive state at or near said temperature.
11. A Magnetic Resonance Imaging (MRI) systems with an imaging volume therein, comprising:
a vacuum vessel positioned about the imaging volume;
at least one high temperature superconducting coil positioned within the vacuum vessel and configured to pass a magnetic field into the imaging volume;
a cryocooler coupled to the vacuum vessel to operate the superconducting coil in a superconductive state while at a temperature above 20 K; and
at least one gradient coil for modulating the magnetic field within the imaging volume, said gradient coil positioned between the imaging volume and the superconducting coil without any thermal shield structure interposed between the gradient coil and the superconducting coil.
12. A method for forming an MRI system comprising the steps of:
providing a main coil formed of a High Temperature Superconductor material within a cryogenically cooled vessel and configuring the main coil to generate a magnetic field within an imaging volume;
providing a gradient coil for adjusting the magnetic field generated by the main coil, operation of the gradient coil contributing to a thermal load within the vessel; and
providing sufficient cooling capacity to the vessel to sustain a desired temperature for energizing the main coil under a thermal load in the absence of a thermal shield structure interposed between the gradient coil and the main coil.
13. The method of claim 12 wherein the step of providing the gradient coil includes positioning the gradient coil within the vessel.
14. A magnetic resonance imaging (MRI) system with an imaging volume therein, comprising;
a cryogenically cooled vessel positioned about the imaging volume;
at least one main coil predominately comprising a High Temperature Superconductor material, said coil configured within the cryogenically cooled vessel for operation in a superconducting state to generate a magnetic field within the imaging volume; and
at least one gradient coil for adjusting the generated magnetic field, wherein said gradient coil comprises a High Temperature Superconductor material and is disposed within said vessel together with said main coil and wherein the operating temperature at which the main coil generates the magnetic field enables said main coil and said gradient coil to operate free of a thermal shield structure interposed between them.
15. The system of claim 14 wherein the main coil is a winding formed of MgB2.
16. The system of claim 14 wherein the main coil is a winding capable of sustaining a critical current density of at least 100 Amps per square cm at a temperature of 20 K.
17. The system of claim 14 further including thermal reservoir material within a portion of the vessel allowing sufficient volume to receive cryogen for heat exchange therein.

1.-30. (canceled)
31. A method for treating a disease mediated at least in part by \u03b14 integrin in a patient, which method comprises administering a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of a compound of formula I
wherein:
R1 is selected from the group consisting of C1 to C4 alkyl and C1 to C4 haloalkyl; and
R2 is selected from the group consisting of C1 to C4 alkyl, C2 to C4 alkenyl, C2 to C4 alkynyl, and C1-C6 cycloalkyl
or a pharmaceutically acceptable salt or ester thereof.
32. A method for reducing andor preventing an inflammatory component of a disease in a mammalian patient which method comprises administering to said mammal the pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of a compound of formula I
wherein:
R1 is selected from the group consisting of C1 to C4 alkyl and C1 to C4 haloalkyl; and
R2 is selected from the group consisting of C1 to C4 alkyl C2 to C4 alkenyl C2 to C4 alkynyl, and C3-C6 cycloalkyl
or a pharmaceutically acceptable salt or ester thereof.
33. A method for reducing andor preventing an autoimmune response in a mammalian patient which method comprises administering to said mammal the pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of a compound of formula I
wherein:
R1 is selected from the group consisting of C1 to C4 alkyl and C1 to C4 haloalkyl, and
R2 is selected from the group consisting of C1 to C4 alkyl, C2 to C4 alkenyl, C2 to C4 alkynyl, and C3-C6 cycloalkyl
or a pharmaceutically acceptable salt or ester thereof.
34. The method of claim 31, wherein the disease is selected from asthma, multiple sclerosis and inflammatory bowel disease.
35. The method of claim 31 wherein the disease is Crohn’s disease.
36. The method of claim 31, wherein the disease is rheumatoid arthritis.
37.-38. (canceled)
39. The method of claim 31, wherein R1 is C1 to C2 alkyl.
40. The method of claim 31, wherein R1 is methyl or trifluoromethyl.
41. The method of claim 31, wherein R1 is methyl.
42. The method of claim 31, wherein R2 is C1 to C4 alkyl.
43. The method of claim 31, wherein R2 is C1 to C3 alkyl.
44. The method of claim 43, wherein R2 is methyl or ethyl.
45. The method of claim 43, wherein R2 is isopropyl.
46. The method of claim 31, wherein R2 is C3 to C6 cycloalkyl.
47. The method of claim 46, wherein R2 is cyclopentyl.
48. The method of claim 31, wherein R2 is C2 to C4 alkenyl.
49. The method of claim 48, wherein R2 is allyl.
50. The method of claim 31, wherein R2 is C2 to C4 alkynyl.
51. The method of claim 50, wherein R2 is propargyl.
52. The method of claim 31, wherein the compound is selected from the group consisting of:
(S)-2-(2-(diethylamino)-5-(N-ethyl-1,1,1-trifluoromethylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-isopropylmethylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(5-(N-cyclopentylmethylsulfonamido)-2-(diethylamino)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-methylmethylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-(prop-2-ynyl)methylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-ethylmethylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(5-(N-allylmethyl sulfonamido)-2-(diethylamino)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid; (S)-2-(2-(diethylamino)-5-(N-ethyl butylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)-propanoic acid;
(S)-2-(5-(3-chloro-N-ethylpropylsulfonamido)-2-(diethylamino)-pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(5-(3-chloro-N-methylpropyl-sulfonamido)-2-(diethylamino)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-ethyl-3,3,3-trifluoropropylsulfonamido)-pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)propanoic acid;
(S)-2-(2-(diethylamino)-5-(N-ethylpropylsulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)phenyl)-propanoic acid; and
(S)-2-(2-(diethylamino)-5-(N-ethyl-2-methylpropyl sulfonamido)pyrimidin-4-ylamino)-3-(4-(pyrrolidine-1-carbonyloxy)-phenyl)propanoic acid;
and pharmaceutically acceptable salts or esters, thereof.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A radio apparatus, comprising:
an antenna that transmits and receives a radio signal;
a modulatingdemodulating module, connected to the antenna, which modulates a transmission signal to a radio-frequency signal, and demodulates a reception signal from a radio-frequency signal;
a signal processing module, connected to the modulatingdemodulating module, which performs signal processing for a transmissionreception signal; and
a CPU, connected to the signal processing module, which performs protocol processing for a transmissionreception signal,
wherein the signal processing module includes plural functional blocks, which perform signal processing for transmission signal data or reception signal data, and whose function is defined by an installed program, and
wherein each of the functional blocks sends, to the functional block of the prior stage, busy state information indicating whether the functional block is in preparation to receive next transmission signal data or next reception signal data as a backward control signal, and outputs, to the functional block of the next stage, transmission signal data or reception signal data having been processed in the functional block when receiving busy state information indicating in preparation to receive next transmission signal data or reception signal data from a functional block of a subsequent stage.
2. The radio apparatus according to claim 1, wherein each of the functional blocks is supplied with a clock signal from a common clock oscillator, performs signal processing according to the clock signal, and transfers the transmission signal data or the reception signal data to a functional block of a prior stage or a subsequent stage according to the clock signal.
3. The radio apparatus according to claim 1, wherein each of the functional blocks outputs, to the functional block of the prior stage, busy state information indicating in preparation to receive the next transmission signal data or the next reception signal data, upon outputting, to the functional block of the subsequent stage, transmission signal data or reception signal data having been processed in the functional block.
4. The radio apparatus according to claim 1, wherein each of the functional blocks:
receives a forward control signal corresponding with the transmission signal data or the reception signal data from the functional block of a prior stage;
performs signal processing for transmission signal data or reception signal data corresponding with the received forward control signal, using the received forward control signal, when the received forward control signal includes information relating to a signal processing of the functional block;
performs signal processing for transmission signal data or reception signal data corresponding with the received forward control signal, without using the received forward control signal, when the received forward control signal does not include information relating to a signal processing of the functional block; and
outputs, to a functional block of a subsequent stage, the processed transmission signal data or the processed reception signal data corresponding with the received forward control signal.
5. The radio apparatus according to claim 4, wherein the forward control signal includes the type of the transmission signal data or the reception signal data corresponding with the received forward control signal, or information indicating whether the transmission signal data or the reception signal data is effective or ineffective.
6. The radio apparatus according to claim 5, wherein the functional blocks dose not performs signal processing when the received forward control signal includes information indicating that the transmission signal data or reception signal data corresponding with the received forward control signal is ineffective.
7. The radio apparatus according to claim 4, wherein the forward control signal is transferred in the same format from a functional block of the forefront stage to a functional block of the final stage of a transmission processing system or a reception processing system, among the plural functional blocks.
8. The radio apparatus according to claim 4,
wherein the CPU notifies the functional block of a change a method of processing the transmission signal data or the reception signal data based on the protocol processing when the change is determined, and notifies the functional block of the forefront stage of a transmission processing system or an reception processing system that information for indicating the change timing is included in the forward control signal corresponding with transmission signal data or reception signal data which is object of the change, and
wherein the functional block notified of the change performs signal processing based on the notified change for the transmission signal data or reception signal data corresponding with the received forward control signal when receiving the forward control signal including the timing information.
9. A radio communication signal processing method in a radio apparatus comprising: an antenna that transmits and receives a radio signal; a modulatingdemodulating module, connected to the antenna, which modulates a transmission signal to a radio-frequency signal, and demodulates a reception signal from a radio-frequency signal; a signal processing module, connected to the modulatingdemodulating module, which performs signal processing for a transmissionreception signal; a CPU, connected to the signal processing module, which performs protocol processing for a transmissionreception signal; plural functional blocks, included in the signal processing module, that perform signal processing for transmission signal data or reception signal data, function of the functional blocks being defined by an installed program, the method comprising:
a first step of sending, to the functional block of the prior stage, busy state information indicating whether the functional block is in preparation to receive next transmission signal data or next reception signal data as a backward control signal, and
a second step of outputting, to the functional block of the next stage, transmission signal data or reception signal data having been subjected to signal processing in the functional block when receiving busy state information indicating in preparation to receive next transmission signal data or reception signal data from a functional block of a subsequent stage.
10. The radio communication signal processing method according to claim 9, further comprising
a third step of supplying each of the functional blocks with a clock signal from a common clock oscillator,
wherein, in the second step, the transmission signal data or the reception signal data is transferred to a functional block of a prior stage or a subsequent stage by using the clock signal.
11. The radio communication signal processing method according to claim 9, further comprising the steps of, in each of the functional blocks, outputting, to the functional block of the prior stage, busy state information indicating in preparation to receive the next transmission signal data or the next reception signal data, upon outputting, to the functional block of the subsequent stage, transmission signal data or reception signal data having been processed in the functional block.
12. The radio communication signal processing method according to claim 9, further comprising:
a fourth step of receiving by each of the functional blocks a forward control signal corresponding with the transmission signal data or the reception signal data from the functional block of a prior stage;
a fifth step of performing signal processing for transmission signal data or reception signal data corresponding with the received forward control signal, using the received forward control signal, when the received forward control signal includes information relating to a signal processing of the functional block, and performing signal processing for transmission signal data or reception signal data corresponding with the received forward control signal, without using the received forward control signal, when the received forward control signal does not include information relating to a signal processing of the functional block.; and
a sixth step of outputting, to a functional block of a subsequent stage, the processed transmission signal data or the processed reception signal data 0corresponding with the received forward control signal.
13. The radio communication signal processing method according to claim 12, further comprising the steps of including in the forward control signal the type of the transmission signal data or the reception signal data corresponding with the received forward control signal, or information indicating whether the transmission signal data or the reception signal data is effective or ineffective.
14. The radio communication signal processing method according to claim 13, wherein, in the fifth step, signal processing in the functional block is not performed when the received forward control signal includes information indicating that the transmission signal data or reception signal data corresponding with the received forward control signal is ineffective.
15. The radio communication signal processing method according to claim 12, further comprising the steps of transferring the forward control signal in the same format from a functional block of the forefront stage to a functional block of the final stage of a transmission processing system or a reception processing system, of the plural functional blocks.
16. The radio communication signal processing method according to claim 12, further comprising:
a seventh step notifying, by the CPU, a functional block of a change a method of processing the transmission signal data or the reception signal data based on the protocol processing when the change is determined;
an eighth step of notifying the functional block of the forefront stage of a transmission processing system or an reception processing system that timing information for indicating the change timing is included in the forward control signal corresponding with transmission signal data or reception signal data which is object of the change, at the same time of performing the seventh step; and
a ninth step of performing, in the functional block notified of the change, signal processing based on the notified change for the transmission signal data or reception signal data corresponding with the received forward control signal when receiving the forward control signal including the timing information.