Author: claimsbot

1. An external-control-type fan coupling device being configured such that an inside of a hermetic housing which is formed of a non-magnetic casing which is supported on a rotary shaft body which mounts a drive disc on a distal end thereof by way of a bearing and a cover which is mounted on the casing is divided into an oil reservoir chamber and a torque transmission chamber which houses the drive disc therein by a partition plate which is mounted on the drive disc, the coupling device includes an oil circulation flow passage which is formed between the torque transmission chamber and the oil reservoir chamber and an oil supply adjustment hole which is formed in the partition plate, the coupling device includes a valve element which opens or closes the oil supply adjustment hole in the oil reservoir chamber, and an openclose control of the oil circulation flow passage is performed by operating the valve element using an actuator, and the rotational torque transmission from a drive side to a driven side is controlled by increasing or decreasing an effective contact area of oil in a torque transmission gap portion defined between the drive side and the driven side, wherein
the coupling device adopts a method in which the actuator is arranged in the inside of the rotary shaft body, a control rod which is operated by the actuator penetrates the inside of the rotary shaft body in the axial direction so as to control the valve element, the coupling device includes a primary coil which is fixed to the outside and a secondary coil which is fixed to the rotary shaft body and faces the primary coil in an opposed manner, and the actuator which is mounted in the rotary shaft body is driven by an electric current induced to the secondary coil.
2. The external-control-type fan coupling device according to claim 1, wherein the coupling device adopts a method which rectifies an AC current induced to the secondary coil into a DC current by a rectifier and the actuator is driven using the DC current.
3. The external-control-type fan coupling device according to claim 2, wherein either one of a rotary-type solenoid type actuator or a linear-type solenoid type actuator is used as the actuator.
4. The external-control-type fan coupling device according to claim 1, wherein either one of a rotary-type solenoid type actuator or a linear-type solenoid type actuator is used as the actuator.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A ready-to-administer parenteral dosage form comprising
a. an aqueous solution comprising
I. therapeutically effective amount of norepinephrine or its pharmaceutically acceptable salt and
II. an antioxidant which is not a sulphite antioxidant

wherein the aqueous solution is stable at room temperature.
2. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein the antioxidant is selected from butylated hydroxyl anisole, ascorbic acid, sodium ascorbate, propyl gallate, vitamin E or alpha-tocopherol.
3. The ready-to-administer parenteral dosage form as claimed in claim 2, wherein the anti-oxidant is butylated hydroxyl anisole.
4. The ready-to-administer parenteral dosage form as claimed in claim 3, wherein butylated hydroxyl anisole is present in the aqueous solution in an amount ranging from about 0.001 mgml to about 0.01 mgml.
5. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein norepinephrine is present in an amount ranging from about 0.001 mgml to about 0.2 mgml.
6. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein norepinephrine or its pharmaceutically acceptable salt is norepinephrine bitartarate.
7. The ready-to-administer parenteral dosage form as claimed in claim 6, wherein norepinephrine bitartarate is present in an amount ranging from about 0.002 mgml to about 0.4 mgml.
8. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein the pH of the aqueous solution is in the range of about 3.0 to about 4.5.
9. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein the aqueous solution is filled in a container, which optionally is further packaged in a secondary packaging, wherein either the container or the secondary packaging is designed to protect the solution from light.
10. The ready-to-administer parenteral dosage form as claimed in claim 9, wherein the container is made up of a material selected from the group comprising polyolefin polymers, polyethylene, polypropylene; cyclo olefin polymers, cyclo olefin copolymers; polypropylene based polyolefin polymers; polycarbonates; modified polyolefin-polyethylene polymers; styrene-polyolefin based polymers and block co-polymers thereof.
11. The ready-to-administer parenteral dosage form as claimed in claim 9, wherein the secondary packaging comprises an aluminium pouch and an oxygen scavenger.
12. The ready-to-administer parenteral dosage form as claimed in claim 9, wherein the container is a pre-filled syringe and wherein norepinephrine is present in the aqueous solution in an amount ranging from about 0.05 mgml to about 0.2 mgml.
13. The ready-to-administer parenteral dosage form as claimed in claim 9, wherein the container is an infusion bag and wherein norepinephrine is present in the aqueous solution in an amount ranging from about 0.004 mgml to about 0.15 mgml.
14. The ready-to-administer parenteral dosage form as claimed in claim 1, wherein the parenteral dosage form is stable at room temperature and wherein the value of total impurities in the aqueous solution is not more than 2.0% by weight upon storage at room temperature or lower for at least 12 months.
15. A ready-to-administer parenteral dosage form comprising an aqueous solution comprising
therapeutically effective amount of norepinephrine or its pharmaceutically acceptable salt an anti-oxidant which is not a sulphite antioxidant
wherein the solution when stored at room temperature for twelve months has less than 4% of S-isomer content.

1. A method of wireless transmission of information, comprising:
(a) transmitting a signal comprising a single preamble randomly selected from among a group of available preambles, at a power level;
(b) determining if number of preamble transmissions has reached a limit;
(c) determining if an acknowledgement corresponding a preamble transmission is received from a base station;
(d) if the number of preamble transmissions has not reached the limit and there has been no receipt of a corresponding acknowledgement, repeating step (a) at a higher power level and repeating steps (b) and (c);
(e) ceasing transmitting of the signal, upon any determination at (b) that the number of preamble transmissions has reached the limit; and
(f) upon any determination at (c) that a corresponding acknowledgement is received from the base station, initiating transmission of information over a wireless spread-spectrum uplink channel to the base station.
2. The method of claim 1, further comprising receiving information over a wireless spread-spectrum downlink channel from the base station.
3. The method of claim 2, wherein the information received from the base station comprises any of packet data and power control information.
4. The method of claim 1, wherein the initiating of transmission of information comprises:
randomly selecting a collision detection symbol from a number of possible collision detection symbols;
transmitting the collision detection symbol at a power level the same as the power level used for the preamble transmission immediately preceding the receipt of the corresponding acknowledgement; and
if a collision detection acknowledgment corresponding to the collision detection symbol is received, transmitting the information over the spread-spectrum uplink channel to the base station.
5. The method of claim 4, wherein the information transmitted to the base station comprises at least one of packet data and power control information.
6. The method of claim 4, further comprising receiving information over a wireless spread-spectrum downlink channel from the base station.
7. The method of claim 6, wherein the information received from the base station comprises any of packet data and power control information.
8. The method of claim 7, wherein during each repetition of transmitting at (a), power level of transmission of the pilot signal increases.
9. The method of claim 1, wherein during each transmitting at (a) the signal further comprises a pilot signal.
10. The method of claim 1, further comprising:
receiving a frame timing signal from the base station;
wherein each transmitting at (a) involves transmitting the signal comprising the single preamble in a time slot randomly selected from among a plurality of possible time slots defined in relation to the received frame timing signal.
11. A method of wireless transmission of information, comprising:
(a) transmitting a signal comprising a single preamble randomly selected from among a group of available preambles, at a power level;
(b) determining if number of preamble transmissions has reached a limit;
(c) determining if an acknowledgement corresponding a preamble transmission is received from the base station;
(d) if the number of preamble transmissions has not reached the limit and there has been no receipt of a corresponding acknowledgement, repeating step (a) at a higher power level, transmitting a pilot symbol, and repeating steps (b) and (c);
(e) ceasing transmitting of the signal, upon any determination at (b) that the number of preamble transmissions has reached the limit;
(f) upon any determination at (c) that a corresponding acknowledgement is received from the base station, randomly selecting a collision detection symbol from among a number of possible collision detection symbols;
(h) transmitting the collision detection symbol at a power level the same as the power level used for the preamble transmission immediately preceding the receipt of the corresponding acknowledgement;
(g) if a collision detection acknowledgment corresponding to the collision detection symbol is received, transmitting information over a wireless spread-spectrum uplink channel to the base station; and
(h) receiving information over a wireless spread-spectrum downlink channel from the base station.
12. The method of claim 11, wherein:
the information transmitted over the wireless spread-spectrum uplink channel to the base station comprises at least one of packet data and power control information; and
the information received over the wireless spread-spectrum downlink channel from the base station comprises at least one of packet data and power control information.
13. The method of claim 11, further comprising:
receiving a frame timing signal from the base station;
wherein each transmitting at (a) comprises transmitting the signal comprising the single selected preamble in a time slot randomly selected from among a plurality of possible time slots defined in relation to the received frame timing signal.
14. A spread-spectrum wireless mobile station, comprising:
a spread-spectrum transmitter;
a spread-spectrum receiver; and
a controller coupled to the spread-spectrum receiver for responding to received signals and coupled for controlling the spread-spectrum transmitter, such that in operation the wireless mobile station performs steps comprising:
(a) transmitting a signal comprising a single preamble randomly selected from among a group of available preambles, at a power level;
(b) determining if number of preamble transmissions has reached a limit;
(c) determining if an acknowledgement corresponding a preamble transmission is received from a base station;
(d) if the number of preamble transmissions has not reached the limit and there has been no receipt of a corresponding acknowledgement, repeating step (a) at a higher power level and repeating steps (b) and (c);
(e) ceasing transmitting of the signal, upon any determination at (b) that the number of preamble transmissions has reached the limit; and
(f) upon any determination at (c) that a corresponding acknowledgement is received from the base station, initiating transmission of information over a wireless spread-spectrum uplink channel to the base station.
15. The mobile station of claim 14, wherein the initiating of transmission of information comprises:
randomly selecting a collision detection symbol from a number of possible collision detection symbols;
transmitting the collision detection symbol at a power level the same as the power level used for the preamble transmission immediately preceding the receipt of the corresponding acknowledgement; and
if a collision detection acknowledgment corresponding to the collision detection symbol is received, transmitting the information over the spread-spectrum uplink channel to the base station.
16. The mobile station of claim 14, wherein at least during a repetition of (a), the signal transmitted further comprises a pilot signal following the selected preamble.
17. The mobile station of claim 14, wherein:
the controller is for controlling operation of the remote station for performing the additional step comprising receiving a frame timing signal from the base station; and
each transmitting of the signal at (a) involves transmitting the signal comprising the single preamble in a time slot randomly selected from among a plurality of possible time slots defined in relation to the received frame timing signal.
18. A base band processor for use in a spread-spectrum wireless remote station, comprising:
an acknowledgment detector for detecting an acknowledgment in received spread-spectrum signals;
a data and control processor, for detecting and processing data and control information contained in received spread-spectrum signals;
a encoder, for encoding data;
a preamble generator for generating preambles;
a multiplexer for multiplexing the encoded data and the preambles;
a packet formatter, coupled to the multiplexer, for formatting the multiplexed data and preambles into packets; and
a controller coupled to the acknowledgment detector for controlling the preamble generator, the multiplexer and the packet formatter, such that in operation the base band processor performs steps comprising:
(a) transmitting a signal comprising a single preamble randomly selected from among a group of available preambles, at a power level;
(b) determining if number of preamble transmissions has reached a limit;
(c) determining if an acknowledgement corresponding a preamble transmission is received from a base station;
(d) if the number of preamble transmissions has not reached the limit and there has been no receipt of a corresponding acknowledgement, repeating step (a) at a higher power level and repeating steps (b) and (c);
(e) ceasing transmitting of the signal, upon any determination at (b) that the number of preamble transmissions has reached the limit; and
(f) upon any determination at (c) that a corresponding acknowledgement is received from the base station, initiating transmission of information over a wireless spread-spectrum uplink channel to the base station.
19. The base band processor of claim 18, wherein the initiating of transmission of information comprises:
randomly selecting a collision detection symbol from a number of possible collision detection symbols;
transmitting the collision detection symbol at a power level the same as the power level used for the preamble transmission immediately preceding the receipt of the corresponding acknowledgement; and
if a collision detection acknowledgment corresponding to the collision detection symbol is received, transmitting the information over the spread-spectrum uplink channel to the base station.
20. The base band processor of claim 18, wherein at least during a repetition of (a), the signal transmitted further comprises a pilot signal following the selected preamble.
21. The base band processor of claim 18, wherein:
the controller is for controlling operation of the base band processor for performing the additional step comprising receiving a frame timing signal from the base station; and
each transmitting of the signal at (a) involves transmitting the signal comprising the single preamble in a time slot randomly selected from among a plurality of possible time slots defined in relation to the received frame timing signal.
22. The base band processor of claim 18, further comprising:
a spread-spectrum modulator for modulating formatted packets from the packet formatter for transmission over the wireless uplink channel; and
a spread-spectrum demodulator for demodulating the received spread-spectrum signals.
23. The base band processor of claim 22, further comprising an interleaver for interleaving encoded data from the encoder and supplying interleaved encoded data to the packet formatter.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A plant, comprising plant cells containing:
a) nucleotide sequence encoding an immunoglobulin single polypeptide product comprising a single immunoglobulin polypeptide containing an immunoglobulin heavy chain, wherein said nucleotide sequence encodes a leader sequence forming a secretion signal for said single polypeptide product, said heavy chain obtained from an antigen-specific immunoglobulin comprising a heavy and light chain, and said single polypeptide product being capable of forming an antigen-specific immunoglobulin when co-expressed in a plant cell with said light chain from said antigen-specific immunoglobulin and wherein said plant cells do not contain nucleic acid encoding light chain; and
b) immunoglobulin single polypeptide product encoded by said nucleotide sequence, wherein said leader sequence is cleaved from said single polypeptide product following proteolytic processing of said single polypeptide product.
2. The plant of claim 1, wherein at least some of said product comprising a single immunoglobulin polypeptide is present within the cell wall of said plant cells.
3. The plant of claim 1, wherein said product comprising a single immunoglobulin polypeptide is trafficked through the Golgi of said plant cells.
4. The plant of claim 1, wherein said product comprising a single immunoglobulin polypeptide associates to form a multimer of said heavy chain.
5. The plant of claim 1, wherein product comprising a single immunoglobulin polypeptide comprises a glycosylated single immunoglobulin polypeptide molecule free of sialic acid residues.
6. The plant of claim 1, wherein the heavy chain is selected from the group consisting of IgG, IgM, IgA, IgD and IgE heavy chains.
7. The plant of claim 1, wherein the plant is a dicotyledonous plant.
8. The plant of claim 1, wherein the plant is a monocotyledonous plant.
9. The plant of claim 1, wherein the plant is an alga.