Author: claimsbot

1. An incubator comprising:
a hand insertion window provided on a side surface of a newborn infant container;
a hand insertion door configured to pivot to open and close said hand insertion window; and
a latch mechanism configured to hold said hand insertion door at a closed position for the closing of said hand insertion window;
a hand insertion door board attached along a peripheral portion of said hand insertion window,
wherein said hand insertion door board is provided with a first lateral side portion located at one lateral end portion of said hand insertion door board and a second lateral side portion located at the other lateral end portion of said hand insertion door board;

a pivot shaft provided on the first lateral side portion of said hand insertion door board, wherein said hand insertion door is supported so as to be pivotal about a vertical axis of said pivot shaft;
a bracket attached and fixed on a holding portion of said hand insertion door board; said latch mechanism comprising a latch lever configured to pivot between a hold position for the holding of said hand insertion door and a release position for releasing the holding of said hand insertion door on the side surface of the newborn infant container and a press lever configured to pivot about an axis identical or parallel to a pivot axis of said latch lever to make said latch lever pivot to the release position, wherein said press lever and said latch lever are separate units, wherein said latch lever is separate from and pivotable within said press lever, wherein said latch mechanism is provided on the second lateral side portion of said hand insertion door board, wherein said latch mechanism holds said hand insertion door at a closed position by pressing a tongue-like portion on a distal end side of said hand insertion door, wherein said latch lever is pivotally supported by a vertical support shaft supported by said bracket, wherein said latch lever is pivotally biased by a biasing spring to cause a distal end side projection to press the tongue-like portion on the distal end side of said hand insertion door so as to hold said hand insertion door at the closed position;
said press lever is pivotally supported by said support shaft on said bracket; and
when said press lever is pressed, said press lever presses a projecting piece of said latch lever to make said latch lever pivot to the release position.
2. An incubator according to claim 1, further comprising:
an opening mechanism configured to bias said hand insertion door in an opening direction by abutting against the hand insertion door during pivoting of said hand insertion door in a closing direction before completion of a closing operation.
3. An incubator according to claim 1, further comprising:
a braking mechanism configured to brake the pivoting of said hand insertion door for at least a portion of an opening operation during the pivoting of said hand insertion door in an opening direction.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A network comprising a plurality of nodes, the plurality of nodes comprising a first node and a second node. the first and second nodes being connected through the network of nodes via a first path and a second path, the first and second paths being different, in which the network has first and second modes of operation, a first mode in which traffic between the first and second nodes is transmitted over the first path and not the second path, and a second mode where the traffic is transmitted over the first and second paths, wherein the network comprises a mode selector arranged to select the mode of operation based upon a demanded level of traffic between the first and second nodes.
2. The network of claim 1, in which the second path comprises a protection path such that the network has a third mode of operation in which traffic between the first and second nodes is sent over only the second path, and in which the mode selector is arranged to select this mode should there be a fault on the first path.
3. The network of claim 1, in which the selection of the mode of operation dependent upon the demanded level of traffic depends upon the rate at which data to be transmitted across the link is received.
4. The network of claim 1, in which the network further comprises a priority assignor, which is operable to assign a priority to the assignment of data between the first and second paths.
5. A network node for use in sending data to a destination node in a network, the network node comprising a first network interface and a second network interface, in which the network node has first and second modes of operation, a first mode in which the network node transmits data for the destination using the first network interface and not the second network interface, and a second mode where the data for the destination node is transmitted over the first and second network interfaces, wherein the network node comprises a mode selector arranged to select the mode of operation based upon a demanded level of traffic for the destination node.
6. The network node of claim 5, in which the first network interface is connectable to a first path across the network to the destination node and the second network interface is connectable to a second path across the network to the destination node.
7. The network node of claim 5, in which the network node comprises a protection switch, whereby in case of a fault traffic for the destination node is sent via the second network interface should there be a fault on a link from the first interface to the destination node.
8. The network node of claim 5, in which the selection of the mode of operation dependent upon the demanded level of traffic depends upon the rate at which data to be transmitted across the link is received.
9. The network node of claim 5, in which the network node further comprises a priority assignor, which is operable to assign a priority to the assignment of data between the first and second paths.
10. A method of operating a network, the network comprising a plurality of nodes, the plurality of nodes comprising a first node and a second node, the first and second nodes being connected through the network of nodes via a first path and a second path, the first and second paths being different,
the method comprising the operation of the network in first and second modes of operation, a first mode in which traffic between the first and second nodes is transmitted over the first path and not the second path, and a second mode where the traffic is transmitted over the first and second paths, and wherein the mode of operation is selected based upon a level of traffic between the first and second nodes.
11. The method of claim 10, in which the second path comprises a protection path such that the network is operated in a third mode of operation in which traffic between the first and second nodes is sent over only the second path, and in which the third mode is selected should there be a fault on the first path.
12. The method of claim 10, in which the selection of the mode of operation dependent upon the demanded level of traffic depends upon the rate at which data to be transmitted across the link is received.
13. The method of claim 12 in which the selection is made dependent upon whether the rate exceeds a threshold.
14. The method of claim 13, in which the threshold is a fraction of an available bandwidth of the first path.
15. The method of claim 10, in which the method comprises the step of assigning a priority to the assignment of data between the first and second paths.
16. The method of claim 15, in which data that is potentially to be routed onto the second path because of a failure in the network is assigned a higher priority than that assigned to data potentially to be assigned to the second path because of traffic levels.
17. A method of operating a network node so as to send data to a destination node in a network, the network node comprising a first network interface and a second network interface, in which the method comprises operating the network node in first and second modes of operation; a first mode in which the network node transmits data For the destination using the first network interface and not the second network interface, and a second mode where the data for the destination node is transmitted over the first and second network interfaces, and wherein the mode is selected based upon a level of traffic for the destination node.

1. A drug delivery system for administration of a pharmaceutically active substance that is a cationic amphiphile by itself and has a solubility per se in water of at least 4 mgml, wherein the drug delivery system comprises nanoparticles smaller than about 50 nm having a solubility in water below 0.1 mgml, said nanoparticles being formed by said substance in association with a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof.
2. A drug delivery system according to claim 1, wherein said nanoparticles have a solubility in water below 0.01 mgml.
3. A drug delivery system according to claim 1, wherein said substance is non-covalently associated with a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof.
4. A drug delivery system according to claim 1, wherein said substance is a cytotoxic or a cytostatic compound.
5. A drug delivery system according to claim 1, wherein said substance is a cytotoxic or cytostatic compound chosen among a protonated form of doxorubicin, mitoxantrone, epirubicin, daunorubicin, idarubicin, topotecan, irinotecan, vinblastine, vincristine, vinorelbine, amsacrine, procarbazine, mechlorethamine, or a combination thereof.
6. A drug delivery system according to claim 4 for use in treatment of cancer.
7. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and the drug delivery system according to claim 1.
8. A pharmaceutical composition according to claim 7 in the form of an aqueous solution, a gel, a cream, an ointment, a tablet, a capsule, or a softgel.
9. A method for the preparation of a drug delivery system for administration of at least one pharmaceutically active substance that is a cationic amphiphile by itself and has a solubility per se in water of at least 4 mgml, wherein said substance is combined with a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof to form nanoparticles smaller than about 50 nm having a solubility in water below 0.1 mgml.
10. A method according to claim 9, wherein a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof is non-covalently bound to said substance.
11. A method according to claim 9, wherein said nanoparticles have a solubility in water below 0.01 mgml.
12. A method for the preparation of pharmaceutical composition comprising a pharmaceutically acceptable carrier and a drug delivery system according to claim 1, wherein said drug delivery system is combined with an amount of about 0.2-10 equivalents, based on the cationic charge of the amphiphile comprised in the drug delivery system, of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof.
13. A method for enhancing the drug efficiency of at least one pharmaceutically active substance that is a cationic amphiphile by itself and has a solubility per se in water of at least 4 mgml, wherein said substance is combined with a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof to form nanoparticles having a solubility in water below 0.1 mgml.
14. A method according to claim 13, wherein a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of the methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof is non-covalently bound to said substance.
15. A method according to claim 13, wherein said substance is combined with an excess of about 0.2-10 equivalents of said sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or combination thereof.
16. A method according to claim 13, wherein said nanoparticles have a solubility in water below 0.01 mgml.
17. A method for increasing the bioavailability of at least one pharmaceutically active substance that is a cationic amphiphile by itself and has a solubility per se in water of at least 4 mgml,
wherein said substance is combined with a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of the methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof to form nanoparticles having a solubility in water below 0.1 mgml.
18. A method according to claim 17, wherein a sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, a sodium salt of the methyl ester of N-13-cis-retinoyl cysteic acid, or a combination thereof is non-covalently bound to said substance.
19. A method according to claim 17, wherein said substance is combined with an excess of about 0.2-10 equivalents of said sodium salt of the methyl ester of N-all-trans-retinoyl cysteic acid, sodium salt of methyl ester of N-13-cis-retinoyl cysteic acid, or combination thereof.
20. A method according to claim 17, wherein said nanoparticles have a solubility in water below 0.01 mgml.
21. A method for the treatment of cancer, wherein a drug delivery system according to claim 1 is administered in a therapeutically effective amount to a patient in need of such treatment.
22. A method for the treatment of cancer, wherein a pharmaceutical composition according to claim 7 in the form of an aqueous solution, a gel, a cream, an ointment, a tablet, a capsule, or a softgel, is administered in a therapeutically effective amount to a patient in need of such treatment.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A system for testing a device, comprising:
a processor in a automatic test operable to:
execute a plurality of test instructions, the plurality of test instructions operable to test a device; the automatic tester not configured to have a radio frequency module;

a test assembly including a high speed data (HSD) module and a radio frequency (RF) module operable to generate a plurality of test signals associated with the plurality of test instructions; and
an interface apparatus coupled to the processor comprising a plurality of connectors operable to communicate the plurality of test signals from the test assembly to the device under test.
2. The system of claim 1, wherein the plurality of test signals comprises a radio frequency signal and a high speed digital signal.
3. The system of claim 1, wherein:
the plurality of test signals comprises a radio frequency signal and a high speed digital signal; and
the plurality of connectors comprises a first connector operable to communicate the radio frequency signal and a second connector operable to communicate the high speed digital signal.
4. The system of claim 1, wherein the interface apparatus comprises a coupling plane, the coupling plane comprising the plurality of connectors arranged in a plurality of rows.
5. The system of claim 1, wherein:
the interface apparatus has an annular shape with an inner edge and an outer edge; and
a portion of the plurality of connectors is arranged in a curved line between the inner edge and the outer edge.
6. The system of claim 1, wherein the the radio frequency module and the high speed data module are located at a test assembly comprising a movable rack, the movable rack operable to transport the test assembly from a first location to a second location.
7. The system of claim 1, wherein the the radio frequency module and the high speed data module are located at a test assembly comprising a movable rack, the movable rack operable to move the test assembly from a first height to a second height.
8. The system of claim 1, further comprising a test head coupled to the interface apparatus and operable to apply the plurality of test signals to the device.
9. The system of claim 1, further comprising a plurality of test modules coupled to the processor, the plurality of test modules operable to transmit the plurality of test signals to the interface apparatus.
10. The system of claim 1, further comprising a handler coupled to the interface apparatus and operable to automatically position the device substantially proximate to the interface apparatus.
11. An interface apparatus for communicating a plurality of signals, comprising:
a plurality of first connectors, each first connector operable to communicate a test signal comprising a radio frequency signal generated by a radio frequency module; and
a plurality of second connectors operable to communicate a test signal comprising a high speed data signal generated by a high speed data module.
12. The interface apparatus of claim 11, further comprising a coupling plane, the coupling plane comprising the plurality of first connectors and the plurality of second connectors arranged in a plurality of rows.
13. The interface apparatus of claim 11, wherein:
the interface apparatus has an annular shape with an inner edge and an outer edge; and
a portion of the plurality of connectors is arranged in a curved line between the inner edge and the outer edge.
14. A method for testing a device, comprising:
executing a plurality of test instructions in a processor in an automatic tester not having a radio frequency module and a high speed data module, the plurality of test instructions operable to test a device;
generating a plurality of test signals associated with the plurality of test instructions in a test assembly including a radio frequency module and a high speed data module; and
communicating the plurality of test signals to the device using an interface apparatus, the interface apparatus comprising a plurality of connectors, each connector operable to communicate at least one signal of the plurality of test signals.
15. The method of claim 14, wherein the plurality of test signals comprises a radio frequency signal and a high speed digital signal.
16. The method of claim 14, wherein the plurality of test signals comprises a radio frequency signal and a high speed digital signal, and further comprising:
communicating the radio frequency signal at a first connector of the plurality of connectors; and
communicating the high speed digital signal at a second connector of the plurality of connectors.
17. The method of claim 14, wherein the interface apparatus comprises a coupling plane, the coupling plane comprising the plurality of connectors arranged in a plurality of rows.
18. The method of claim 14, wherein:
the interface apparatus has an annular shape with an inner edge and an outer edge; and
a portion of the plurality of connectors is arranged in a curved line between the inner edge and the outer edge.
19. A system for testing a device, comprising:
a processor in an automatic tester, which does not include a radio frequency module and a high speed data module, operable to execute a plurality of test instructions, the plurality of test instructions operable to test a device; and
a test assembly including a high speed data (HSD) module and a radio frequency (RF) module operable to generate a plurality of test signals associated with the plurality of test instructions, the plurality of test signals comprising a radio frequency signal and a high speed digital signal, located at a test assembly comprising a movable rack, the movable rack operable to transport the test assembly from a first location to a second location; and move the test assembly from a first height to a second height;
an interface apparatus coupled to the processor and operable to communicate the plurality of test signals to the device, the interface apparatus comprising a coupling plane, the coupling plane comprising a plurality of connectors arranged in a plurality of rows, the interface apparatus having an annular shape with an inner edge and an outer edge, a portion of the plurality of connectors arranged in a curved line between the inner edge and the outer edge, each connector of the plurality of connectors operable to communicate at least one signal of the plurality of test signals, the plurality of connectors comprising a first connector operable to communicate the radio frequency signal and a second connector operable to communicate the high speed digital signal;
a plurality of test modules coupled to the processor, the plurality of test modules operable to transmit the plurality of test signals to the interface apparatus;
a test head coupled to the interface apparatus and operable to apply the plurality of test signals to the device; and
a handler coupled to the interface apparatus and operable to automatically position the device substantially proximate to the interface apparatus.