All The Claims

1. A method of displaying information in a mobile terminal, comprising:
receiving a message that includes text information and attached files, each attached file being a separate file from other files of the attached files; and
simultaneously displaying content from each of a predetermined number of the attached files with the text information on a screen of the mobile terminal when the message is opened, wherein the content from each of the predetermined number of the attached files is displayed at a predetermined location of the message on the screen,
wherein, when a number of the attached files is greater than the predetermined number, the content from each of the attached files is set to be displayed sequentially at said predetermined location, at least one scroll bar indicative of an amount of content from one or more of the attached files to be displayed is provided on the screen, and the content being scrolled based on input to move the scroll bar.
2. The method of claim 1, further comprising:
converting the message into a file of a predetermined format set to execute a number of attached files; and driving the converted files in response to activation of a key confirming the message.
3. The method of claim 2, wherein each file is in a format compatible with a synchronized multimedia integration language (SMIL).
4. The method of claim 2, wherein converting process includes allotting display areas for the predetermined number of attached files and the text to allow the content from the predetermined number of attached files and text to be simultaneously displayed based on display-specifying data stored in a memory of the terminal, wherein the display-specifying data include the predetermined setting.
5. The method of claim 4, further comprising:
receiving the display-specifying data to be stored in a memory.
6. The method of claim 5, wherein the display-specifying data includes data indicating whether a sound file is to be executed and data indicating when the sound file to be executed.
7. The method of claim 4, further comprising:
comparing the number of attached files to the predetermined number, and
wherein the predetermined number corresponds to the number of allotted display areas for displaying content from the number of attached files, and wherein said number of allotted display areas is included at said at least one location.
8. The method of claim 7, wherein the content from the number of attached files is set to be displayed sequentially and rotationally in at least one of said number of allotted display areas with a predetermined cycle.
9. The method of claim 8, wherein the predetermined cycle is set based on the display-specifying data.
10. The method of claim 1, wherein the content from the number of the attached files is displayed sequentially and rotationally at said predetermined location on the screen of the mobile terminal.
11. The method of claim 1, wherein the content from the number of attached files is automatically displayed sequentially and rotationally at said predetermined location on the screen of the mobile terminal.
12. The method of claim 1, wherein the content from the number of attached files is sequentially displayed according to a predetermined cycle.
13. The method of claim 12, wherein the predetermined cycle is set by a user of the mobile terminal.
14. The method of claim 12, wherein the predetermined cycle is adjustable.
15. The method of claim 14, wherein the predetermined cycle is adjustable based on control information stored in the mobile terminal.
16. The method of claim 1, wherein said displaying includes:
displaying the text and the content from at least one of the number of attached files in screen areas allotted based on display-specifying data corresponding to the predetermined setting stored in a memory by the user before the message is received,
wherein the text information is displayed in a first window and the content from the number of the attached files is sequentially displayed in a second window, the predetermined setting causing the content from the number of the attached files to be displayed in the second window in non-overlapping relationship with the first window so that the sequentially displayed content from the number of the attached files are displayed in the second window does not obscure any information including the text in the first window.
17. The method of claim 16, wherein the display-specifying data is input by a user using an input menu.
18. The method of claim 1, wherein the text is displayed in a first area and the content from at least one of the predetermined number of attached files is displayed in a second area of the screen of the mobile terminal.
19. The method of claim 18, further comprising:
changing areas of the screen where the text and content from the number of attached files are to be displayed, the areas being changed by changing the predetermined setting stored in a memory of the mobile terminal.
20. The method of claim 1, wherein said displaying includes:
simultaneously displaying content from at least two of the number of the attached files on the screen of the mobile terminal.
21. The method of claim 1, wherein the content from at least one of the predetermined number of attached files includes one or more images.
22. The method of claim 1, wherein the text information of the message is included in a body of the message.
23. The method of claim 1, wherein the text information of the message is included in a header of the message.
24. The method of claim 1, wherein the content from the number of attached files is sequentially displayed one-by-one at said predetermined location with the text.
25. The method of claim 1, wherein the content from the number of the attached files is set to be displayed sequentially at said predetermined location, the content from the number of the attached files is automatically displayed one-by-one at said predetermined location, and wherein the content from each of the number of attached files is displayed for a predetermined time duration at said predetermined location.
26. The method of claim 1, wherein the content from the predetermined number of attached files on the screen is independent from link information in any of the attached files or in the text information of the message.
27. The method of claim 1, wherein the content from the predetermined number of attached files is provided below the text information in the message.
28. The method of claim 1, wherein the text information is scrolled when the entire text information cannot be displayed on the screen.
29. The method of claim 1, wherein the content from the predetermined number of attached files is simultaneously displayed with the text information within the screen of a message program that is different from a word processing program.
30. An apparatus for displaying information on a mobile terminal comprising:
a control circuit which simultaneously displays text information and content from each of a predetermined number of attached files of a received message when the message is opened, wherein said number is greater than one and each attached file is a separate file from other files of the attached files; and
a message display setting module which specifies the content from each of the predetermined number of attached files to be displayed simultaneously with text,
wherein the content from each of the predetermined number of attached files is displayed at a predetermined location of the message on a screen of the mobile terminal; and
wherein, when a number of the attached files is greater than the predetermined number, the content from each of the attached files is set to be displayed sequentially at said predetermined location, at least one scroll bar indicative of an amount of content from one or more of the attached files to be displayed is provided on the screen, and the content being scrolled based on input to move the scroll bar.
31. The apparatus of claim 30, wherein the message display setting module converts the message into a file of a predetermined format set to execute and display the content from the predetermined number of attached files simultaneously with the text, the control circuit displaying a message by driving the file in response to activation of a key indicating the confirmation of the message.
32. The apparatus of claim 31, wherein each file is in a format compatible with synchronized multimedia integration language (SMIL).
33. The apparatus of claim 31, wherein the message display setting module allots display areas for the content from the predetermined number of attached files and text, where the content from the predetermined number of the attached files and text are simultaneously displayed at said display areas respectively based on display-specifying data stored in the memory.
34. The apparatus of claim 33, wherein the display-specifying data is input by user to be stored in a memory.
35. The apparatus of claim 34,
wherein the predetermined number corresponds to the number of allotted displaying areas for displaying the content from the number of attached files, and wherein said number of allotted display areas is included at said location.
36. The apparatus of claim 35, wherein the message display setting module sets the content from the number of attached files to be displayed sequentially and rotationally in said number of allotted display areas with a predetermined cycle.
37. The apparatus of claim 36, wherein the message display setting module sets the predetermined cycle using the display-specifying data.
38. The method of claim 30, wherein the text is displayed in a first window and the content from at least a portion of the number of the attached files is sequentially displayed in a second window, the predetermined setting stored in a memory by the user causing the content from at least the portion of the number of the attached files to be sequentially displayed in the second window in non-overlapping relationship with the first window so that the content from at least the portion of the number of the attached files displayed in the second window does not obscure any information including the text in the first window.
39. The apparatus from claim 30, wherein the content from the predetermined number of attached files is simultaneously displayed with the text information within the screen of a message program that is different from a word processing program.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method of treating or preventing a proliferative disorder in a mammal, comprising administering to the mammal an effective amount of a compound represented by the following structural formula:
or a tautomer, pharmaceutically acceptable salt, solvate, clathrate or a prodrug thereof, wherein:
R1, R2 and R3 are independently \u2014OH, \u2014SH, \u2014NR7H, \u2014OR26, \u2014SR26, \u2014O(CH2)mOH, \u2014O(CH2)mSH, \u2014O(CH2)mNR7H, \u2014S(CH2)mOH, \u2014S(CH2)mSH, \u2014S(CH2)mNR7H, \u2014OC(O)NR10R11, \u2014SC(O)NR10R11, \u2014NR7C(O)NR10R11, \u2014OC(O)R7, \u2014SC(O)R7, \u2014NR7C(O)R7, \u2014OC(O)OR7, \u2014SC(O)OR7, \u2014NR7C(O)OR7, \u2014OCH2C(O)R7, \u2014SCH2C(O)R7, \u2014NR7CH2C(O)R7, \u2014OCH2C(O)OR7, \u2014SCH2C(O)OR7, \u2014NR7CH2C(O)OR7, \u2014OCH2C(O)NR10R11, \u2014SCH2C(O)NR10R11, \u2014NR7CH2C(O)NR10R11, \u2014OS(O)pR7, \u2014SS(O)pR7, \u2014S(O)pOR7, \u2014NR7S(O)pR7, \u2014OS(O)pNR10R11, \u2014SS(O)pNR10R11, \u2014NR7S(O)pNR10R11, \u2014OS(O)pOR7, \u2014SS(O)pOR7, \u2014NR7S(O)pOR7, \u2014OC(S)R7, \u2014SC(S)R7, \u2014NR7C(S)R7, \u2014OC(S)OR7, \u2014SC(S)OR7, \u2014NR7C(S)OR7, \u2014OC(S)NR10R11, \u2014SC(S)NR10R11, \u2014NR7C(S)NR10R11, \u2014OC(NR8)R7, \u2014SC(NR8)R7, \u2014NR7C(NR8)R7, \u2014OC(NR8)OR7, \u2014SC(NR8)OR7, \u2014NR7C(NR8)OR7, \u2014OC(NR8)NR10R11, \u2014SC(NR8)NR10R11, \u2014NR7C(NR8)NR10R11, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, provided that at least one of R1, R2 and R3 is \u2014OP(O)(OH)2;
R5 is \u2014X20R50, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl;
R7 and R8, for each occurrence, is independently, \u2014H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl;
R10 and R11, for each occurrence, is independently \u2014H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl; or R10 and R11, taken together with the nitrogen to which they are attached, form an optionally substituted heterocyclyl or an optionally substituted heteroaryl;
R26 is a lower alkyl;
R50 is an optionally substituted aryl or an optionally substituted heteroaryl;
X20 is a C1-C4 alkyl, NR7, C(O), C(S), C(NR8), or S(O)p;
Z is a substituent;
p, for each occurrence, is independently, 1 or 2;
m for each occurrence, is independently 1, 2, 3, or 4; and
n is 0, 1, 2, or 3; and
with the proviso that the compound is not 3-hydroxy-4-(5-mercapto-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)phenyl dihydrogen phosphate.
2. The method of claim 1, wherein Z is a C1-C6 alkyl, a C1-C6 haloalkyl, a C1-C6 alkoxy, a C1-C6 haloalkoxy, a C1-C6 alkyl sulfanyl or a C3-C6 cycloalkyl.
3. The method of claim 1, wherein the compound is represented by the following structural formula:
wherein R6 is an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, cyano, halo, nitro, an optionally substituted cycloalkyl, haloalkyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteroaralkyl, \u2014OR7, \u2014SR7, \u2014NR10R11, \u2014OC(O)NR10R11, \u2014SC(O)NR10R11, \u2014NR7C(O)NR10R11, \u2014OC(O)R7, \u2014SC(O)R7, \u2014NR7C(O)R7, \u2014OC(O)OR7, \u2014SC(O)OR7, \u2014NR7C(O)OR7, \u2014OCH2C(O)R7, \u2014SCH2C(O)R7, \u2014NR7CH2C(O)R7, \u2014OCH2C(O)OR7, \u2014SCH2C(O)OR7, \u2014NR7CH2C(O)OR7, \u2014OCH2C(O)NR10R11, \u2014SCH2C(O)NR10R11, \u2014NR7CH2C(O)NR10R11, \u2014OS(O)pR7, \u2014SS(O)pR7, \u2014NR7S(O)pR7, \u2014OS(O)pNR10R11, \u2014SS(O)pNR10R11, \u2014NR7S(O)pNR10R11, \u2014OS(O)pOR7, \u2014SS(O)pOR7, \u2014NR7S(O)pOR7, \u2014OC(S)R7, \u2014SC(S)R7, \u2014NR7C(S)R7, \u2014OC(S)OR7, \u2014SC(S)OR7, \u2014NR7C(S)OR7, \u2014OC(S)NR10R11, \u2014SC(S)NR10R11, \u2014NR7C(S)NR10R11, \u2014OC(NR8)R7, \u2014SC(NR8)R7, \u2014NR7C(NR8)R7, \u2014OC(NR8)OR7, \u2014SC(NR8)OR7, \u2014NR7C(NR8)OR7, \u2014OC(NR8)NR10R11, \u2014SC(NR8)NR10R11, \u2014NR7C(NR8)NR10R11, \u2014C(O)R7, \u2014C(O)OR7, \u2014C(O)NR10R11, \u2014C(O)SR7, \u2014C(S)R7, \u2014C(S)OR7, \u2014C(S)NR10R11, \u2014C(S)SR7, \u2014C(NR8)OR7, \u2014C(NR8)R7, \u2014C(NR8)NR10R11, \u2014C(NR8)SR7, \u2014S(O)pOR7, \u2014S(O)pNR10R11, or \u2014S(O)pR7.
4. The method of claim 1, wherein one of R1, R2, or R3 is \u2014OP(O)(OH)2.
5. The method of claim 3, wherein the compound is represented by the following structural formula:
6. The method of claim 5, wherein R5 is represented by the following formula:
wherein:
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, hydroxyalkyl, alkoxyalkyl, halo, cyano, nitro, guanadino, a haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
q is zero or an integer from 1 to 7.
7. The method of claim 5, wherein R5 is represented by the following formula:
wherein:
R33 is a halo, lower alkyl, a lower alkoxy, a lower haloalkyl, a lower haloalkoxy, and lower alkyl sulfanyl;
R34 is H, a lower alkyl, or a lower alkylcarbonyl; and
Ring B and Ring C are optionally substituted with one or more substituents.
8. The method of claim 5, wherein R5 is selected from the group consisting of:
wherein:
X6, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least three X6 groups are independently selected from CH and CR9;
X7, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least three X7 groups are independently selected from CH and CR9;
X8, for each occurrence, is independently CH2, CHR9, C(R9)2, S, S(O)p, NR7, or NR17;
X9, for each occurrence, is independently N or CH;
X10, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least one X10 is selected from CH and CR9;
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, hydroxyalkyl, alkoxyalkyl, halo, cyano, nitro, guanadino, a haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
R17, for each occurrence, is independently \u2014H, an alkyl, an aralkyl, \u2014C(O)R7, \u2014C(O)OR7, or \u2014C(O)NR10R11.
9. The method of claim 8, wherein R5 is an optionally substituted indolyl, an optionally substituted benzoimidazolyl, an optionally substituted indazolyl, an optionally substituted 3H-indazolyl, an optionally substituted indolizinyl, an optionally substituted quinolinyl, an optionally substituted isoquinolinyl, an optionally substituted benzoxazolyl, an optionally substituted benzo1,3dioxolyl, an optionally substituted benzofuryl, an optionally substituted benzothiazolyl, an optionally substituted benzodisoxazolyl, an optionally substituted benzodisothiazolyl, an optionally substituted thiazolo4,5-cpyridinyl, an optionally substituted thiazolo5,4-cpyridinyl, an optionally substituted thiazolo4,5-bpyridinyl, an optionally substituted thiazolo5,4-bpyridinyl, an optionally substituted oxazolo4,5-cpyridinyl, an optionally substituted oxazolo5,4-cpyridinyl, an optionally substituted oxazolo4,5-bpyridinyl, an optionally substituted oxazolo5,4-bpyridinyl, an optionally substituted imidazopyridinyl, an optionally substituted benzothiadiazolyl, benzoxadiazolyl, an optionally substituted benzotriazolyl, an optionally substituted tetrahydroindolyl, an optionally substituted azaindolyl, an optionally substituted quinazolinyl, an optionally substituted purinyl, an optionally substituted imidazo4,5-apyridinyl, an optionally substituted imidazo1,2-apyridinyl, an optionally substituted 3H-imidazo4,5-bpyridinyl, an optionally substituted 1H-imidazo4,5-bpyridinyl, an optionally substituted 1H-imidazo4,5-cpyridinyl, an optionally substituted 3H-imidazo4,5-cpyridinyl, an optionally substituted pyridopyrdazinyl, and optionally substituted pyridopyrimidinyl, an optionally substituted pyrrolo2,3pyrimidyl, an optionally substituted pyrazolo3,4pyrimidyl an optionally substituted cyclopentaimidazolyl, an optionally substituted cyclopentatriazolyl, an optionally substituted pyrrolopyrazolyl, an optionally substituted pyrroloimidazolyl, an optionally substituted pyrrolotriazolyl, or an optionally substituted benzo(b)thienyl.
10. The method of claim 5, wherein R5 is selected from the group consisting of:
wherein:
X11, for each occurrence, is independently CH, CR9, N, N(O), or N+(R17);
X12, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least one X12 group is independently selected from CH and CR9;
X13, for each occurrence, is independently O, S, S(O)p, NR7, or NR17;
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, halo, cyano, nitro, guanadino, a hydroxyalkyl, alkoxyalkyl, haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
R17, for each occurrence, is independently an alkyl or an aralkyl.
11. The method of claim 1, where the proliferative disorder is cancer.
12. The method of claim 1, where the mammal is a human.
13. The method of claim 11, where the mammal is a human.
14. A method of blocking, occluding, or otherwise disrupting blood flow in neovasculature, comprising contacting the neovasculature with an effective amount of a compound represented by the following structural formula:
or a tautomer, pharmaceutically acceptable salt, solvate, clathrate or a prodrug thereof, wherein:
R1, R2 and R3 are independently \u2014OH, \u2014SH, \u2014NR7H, \u2014OR26, \u2014SR26, \u2014O(CH2)mOH, \u2014O(CH2)mSH, \u2014O(CH2)mNR7H, \u2014S(CH2)mOH, \u2014S(CH2)mSH, \u2014S(CH2)mNR7H, \u2014OC(O)NR10R11, \u2014SC(O)NR10R11, \u2014NR7C(O)NR10R11, \u2014OC(O)R7, \u2014SC(O)R7, \u2014NR7C(O)R7, \u2014OC(O)OR7, \u2014SC(O)OR7, \u2014NR7C(O)OR7, \u2014OCH2C(O)R7, \u2014SCH2C(O)R7, \u2014NR7CH2C(O)R7, \u2014OCH2C(O)OR7, \u2014SCH2C(O)OR7, \u2014NR7CH2C(O)OR7, \u2014OCH2C(O)NR10R11, \u2014SCH2C(O)NR10R11, \u2014NR7CH2C(O)NR10R11, \u2014OS(O)pR7, \u2014SS(O)pR7, \u2014S(O)pOR7, \u2014NR7S(O)pR7, \u2014OS(O)pNR10R11, \u2014SS(O)pNR10R11, \u2014NR7S(O)pNR10R11, \u2014OS(O)pOR7, \u2014SS(O)pOR7, \u2014NR7S(O)pOR7, \u2014OC(S)R7, \u2014SC(S)R7, \u2014NR7C(S)R7, \u2014OC(S)OR7, \u2014SC(S)OR7, \u2014NR7C(S)OR7, \u2014OC(S)NR10R11, \u2014SC(S)NR10R11, \u2014NR7C(S)NR10R11, \u2014OC(NR8)R7, \u2014SC(NR8)R7, \u2014NR7C(NR8)R7, \u2014OC(NR8)OR7, \u2014SC(NR8)OR7, \u2014NR7C(NR8)OR7, \u2014OC(NR8)NR10R11, \u2014SC(NR8)NR10R11, \u2014NR7C(NR8)NR10R11, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, provided that at least one of R1, R2 and R3 is \u2014OP(O)(OH)2;
R5 is \u2014X20R50, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl;
R7 and R8, for each occurrence, is independently, \u2014H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl;
R10 and R11, for each occurrence, is independently \u2014H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl; or R10 and R11, taken together with the nitrogen to which they are attached, form an optionally substituted heterocyclyl or an optionally substituted heteroaryl;
R26 is a lower alkyl;
R50 is an optionally substituted aryl or an optionally substituted heteroaryl;
X20 is a C1-C4 alkyl, NR7, C(O), C(S), C(NR8), or S(O)p;
Z is a substituent;
p, for each occurrence, is independently, 1 or 2;
m for each occurrence, is independently 1, 2, 3, or 4; and
n is 0, 1, 2, or 3; and
with the proviso that the compound is not 3-hydroxy-4-(5-mercapto-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)phenyl dihydrogen phosphate.
15. The method of claim 14, wherein Z is a C1-C6 alkyl, a C1-C6 haloalkyl, a C1-C6 alkoxy, a C1-C6 haloalkoxy, a C1-C6 alkyl sulfanyl or a C3-C6 cycloalkyl.
16. The method of claim 14, wherein the compound is represented by the following structural formula:
wherein R6 is an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, cyano, halo, nitro, an optionally substituted cycloalkyl, haloalkyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteroaralkyl, \u2014OR7, \u2014SR7, \u2014NR10R11, \u2014OC(O)NR10R11, \u2014SC(O)NR10R11, \u2014NR7C(O)NR10R11, \u2014OC(O)R7, \u2014SC(O)R7, \u2014NR7C(O)R7, \u2014OC(O)OR7, \u2014SC(O)OR7, \u2014NR7C(O)OR7, \u2014OCH2C(O)R7, \u2014SCH2C(O)R7, \u2014NR7CH2C(O)R7, \u2014OCH2C(O)OR7, \u2014SCH2C(O)OR7, \u2014NR7CH2C(O)OR7, \u2014OCH2C(O)NR10R11, \u2014SCH2C(O)NR10R11, \u2014NR7CH2C(O)NR10R11, \u2014OS(O)pR7, \u2014SS(O)pR7, \u2014NR7S(O)pR7, \u2014OS(O)pNR10R11, \u2014SS(O)pNR10R11, \u2014NR7S(O)pNR10R11, \u2014OS(O)pOR7, \u2014SS(O)pOR7, \u2014NR7S(O)pOR7, \u2014OC(S)R7, \u2014SC(S)R7, \u2014NR7C(S)R7, \u2014OC(S)OR7, \u2014SC(S)OR7, \u2014NR7C(S)OR7, \u2014OC(S)NR10R11, \u2014SC(S)NR10R11, \u2014NR7C(S)NR10R11, \u2014OC(NR8)R7, \u2014SC(NR8)R7, \u2014NR7C(NR8)R7, \u2014OC(NR8)OR7, \u2014SC(NR8)OR7, \u2014NR7C(NR8)OR7, \u2014OC(NR8)NR10R11, \u2014SC(NR8)NR10R11, \u2014NR7C(NR8)NR10R11, \u2014C(O)R7, \u2014C(O)OR7, \u2014C(O)NR10R11, \u2014C(O)SR7, \u2014C(S)R7, \u2014C(S)OR7, \u2014C(S)NR10R11, \u2014C(S)SR7, \u2014C(NR8)OR7, \u2014C(NR8)R7, \u2014C(NR8)NR10R11, \u2014C(NR8)SR7, \u2014S(O)pOR7, \u2014S(O)pNR10R11, or \u2014S(O)pR7.
17. The method of claim 14, wherein one of R1, R2, or R3 is \u2014OP(O)(OH)2.
18. The method of claim 16, wherein the compound is represented by the following structural formula:
19. The method of claim 18, wherein R5 is represented by the following formula:
wherein:
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, hydroxyalkyl, alkoxyalkyl, halo, cyano, nitro, guanadino, a haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
q is zero or an integer from 1 to 7.
20. The method of claim 18, wherein R5 is represented by the following formula:
wherein:
R33 is a halo, lower alkyl, a lower alkoxy, a lower haloalkyl, a lower haloalkoxy, and lower alkyl sulfanyl;
R34 is H, a lower alkyl, or a lower alkylcarbonyl; and
Ring B and Ring C are optionally substituted with one or more substituents.
21. The method of claim 18, wherein R5 is selected from the group consisting of:
wherein:
X6, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least three X6 groups are independently selected from CH and CR9;
X7, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least three X7 groups are independently selected from CH and CR9;
X8, for each occurrence, is independently CH2, CHR9, C(R9)2, S, S(O)p, NR7, or NR17;
X9, for each occurrence, is independently N or CH;
X10, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least one X10 is selected from CH and CR9;
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, hydroxyalkyl, alkoxyalkyl, halo, cyano, nitro, guanadino, a haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
R17, for each occurrence, is independently \u2014H, an alkyl, an aralkyl, \u2014C(O)R7, \u2014C(O)OR7, or \u2014C(O)NR10R11.
22. The method of claim 21, wherein R5 is an optionally substituted indolyl, an optionally substituted benzoimidazolyl, an optionally substituted indazolyl, an optionally substituted 3H-indazolyl, an optionally substituted indolizinyl, an optionally substituted quinolinyl, an optionally substituted isoquinolinyl, an optionally substituted benzoxazolyl, an optionally substituted benzo1,3dioxolyl, an optionally substituted benzofuryl, an optionally substituted benzothiazolyl, an optionally substituted benzodisoxazolyl, an optionally substituted benzodisothiazolyl, an optionally substituted thiazolo4,5-bpyridinyl, an optionally substituted thiazolo5,4-cpyridinyl, an optionally substituted thiazolo4,5-bpyridinyl, an optionally substituted thiazolo5,4-bpyridinyl, an optionally substituted oxazolo4,5-cpyridinyl, an optionally substituted oxazolo5,4-cpyridinyl, an optionally substituted oxazolo4,5-bpyridinyl, an optionally substituted oxazolo5,4-bpyridinyl, an optionally substituted imidazopyridinyl, an optionally substituted benzothiadiazolyl, benzoxadiazolyl, an optionally substituted benzotriazolyl, an optionally substituted tetrahydroindolyl, an optionally substituted azaindolyl, an optionally substituted quinazolinyl, an optionally substituted purinyl, an optionally substituted imidazo4,5-apyridinyl, an optionally substituted imidazo1,2-apyridinyl, an optionally substituted 3H-imidazo4,5-bpyridinyl, an optionally substituted 1H-imidazo4,5-bpyridinyl, an optionally substituted 1H-imidazo4,5-cpyridinyl, an optionally substituted 3H-imidazo4,5-cpyridinyl, an optionally substituted pyridopyrdazinyl, and optionally substituted pyridopyrimidinyl, an optionally substituted pyrrolo2,3pyrimidyl, an optionally substituted pyrazolo3,4pyrimidyl an optionally substituted cyclopentaimidazolyl, an optionally substituted cyclopentatriazolyl, an optionally substituted pyrrolopyrazolyl, an optionally substituted pyrroloimidazolyl, an optionally substituted pyrrolotriazolyl, or an optionally substituted benzo(b)thienyl.
23. The method of claim 18, wherein R5 is selected from the group consisting of:
wherein:
X11, for each occurrence, is independently CH, CR9, N, N(O), or N+(R17);
X12, for each occurrence, is independently CH, CR9, N, N(O), N+(R17), provided that at least one X12 group is independently selected from CH and CR9;
X13, for each occurrence, is independently O, S, S(O)p, NR7, or NR17;
R9, for each occurrence, is independently a substituent selected from the group consisting of an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, an optionally substituted heteraralkyl, halo, cyano, nitro, guanadino, a hydroxyalkyl, alkoxyalkyl, haloalkyl, a heteroalkyl, \u2014NR10R11, \u2014OR7, \u2014C(O)R7, \u2014C(O)OR7, \u2014OC(O)R7, \u2014C(O)NR10R11, \u2014NR8C(O)R7, \u2014SR7, \u2014S(O)pR7, \u2014OS(O)pR7, \u2014S(O)pOR7, \u2014NR8S(O)pR7, or \u2014S(O)pNR10R11, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2, \u2014S(O)pOR7, \u2014OP(O)(OR7)2, or \u2014SP(O)(OR7)2;
or two R9 groups taken together with the carbon atoms to which they are attached form a fused ring; and
R17, for each occurrence, is independently an alkyl or an aralkyl.
24. The method of claim 14, wherein the neovasculature is in a subject and blood flow in the neovasculature is blocked, occluded, or otherwise disrupted in the subject by administering to the subject an effective amount of the compound.
25. The method of claim 24, wherein the subject is human.

1. A method, comprising:
introducing a channel through a first node and a second node, wherein the channel is introduced simultaneously over the first node and the second node;
measuring power of the channel entering the first node and the channel entering the second node;
determining a first measured error of the channel based on a first target power and the measured power at the first node and a second measured error of the channel based on a second target power and the measured power at the second node;
performing a control loop using the first measured error at the first node and using the second measured error at the second node, wherein the first node and the second node perform the control loop simultaneously and independently of one another, and wherein each of the first node and the second node perform the control loop based only on their own measurements;
modifying parameters of the control loop at each of the first node and the second node with a plurality of states to maintain a stable response; and
adjusting power of the channel based on the modified control loop at each of the first node and the second node.
2. The method of claim 1, further comprising:
modifying the control loop at each of the first node and the second node to set a derivative coefficient to zero if an overshoot is detected in a previous iteration of the control loop.
3. The method of claim 1, further comprising:
modifying the control loop at each of the first node and the second node to select coefficients in such a way that a response remains always damped until complete convergence.
4. The method of claim 1, further comprising:
performing the control loop initially at each of the first node and the second node with coefficients selected for a damped unit step response;
modifying the control loop at the first node with a first damping factor once absolute magnitude of the first measured error is below a first threshold when the first node is not an ingress node for the channel;
modifying the control loop at the second node with the first damping factor once absolute magnitude of the second measured error is below the first threshold when the second node is not an ingress node for the channel;
modifying the control loop at the first node with a second damping factor once absolute magnitude of the first measured error is below a second threshold when the first node is not an ingress node for the channel; and
modifying the control loop at the second node with the second damping factor once absolute magnitude of the second measured error is below the second threshold when the second node is not an ingress node for the channel.
5. The method of claim 4, further comprising:
setting a proportional coefficient and an integral coefficient of the coefficients to zero at the first node when the first measured error is below the second threshold; and
setting the proportional coefficient and the integral coefficient of the coefficients to zero at the second node when the second measured error is below the second threshold.
6. The method of claim 1, further comprising:
modifying the control loop at the second node with an expected error change offset to dampen a response due to variable input power from the first node.
7. The method of claim 1, further comprising:
determining a first drive offset parameter for each iteration of the control loop to compensate for plant drift and aging effects at the first node; and
determining a second drive offset parameter for each iteration of the control loop to compensate for plant drift and aging effects at the second node.
8. The method of claim 1, wherein the first node and the second node utilize a same set of parameters and a same set of rules for adjusting the parameters, and wherein the first node and the second node do not communicate with one another with respect to the control loop.
9. The method of claim 8, wherein the second node is downstream from the first node, and wherein the second node utilizes the control loop and associated modifications to adjust the power of the channel while the first node is converging to its target power.
10. The method of claim 1, wherein the channel comprises a first channel, and further comprising:
introducing a second channel through the first node and the second node, wherein the second channel is introduced in parallel over the first node and the second node; and
performing the measuring, the determining, the performing, the modifying, and the adjusting steps with respect to the second channel independent of the first channel with independent parameters.
11. The method of claim 1, further comprising:
adjusting the power of the channel based on the modified control loop at each of the first node and the second node with any of a wavelength selective switch, a variable optical attenuator, an optical amplifier, and a dynamic gain equalizer.
12. The method of claim 1, wherein the channel comprises any of a wavelength, a group of wavelengths, a range of wavelengths, and a band of wavelengths.
13. An optical node, comprising:
at least one degree comprising components configured to selectively alter power of a channel being added to the at least one degree;
an optical power monitor measuring an output power of the channel out of the at least one degree; and
a power controller communicatively coupled to the at least one degree and the optical power monitor, wherein the power controller is configured to:
measure power of the channel being added to the at least one degree, wherein the channel is being added simultaneously over at least one additional node;
determine a measured error of the channel based on a target power and the measured power;
perform a control loop using the measured error, wherein the at least one additional node performs the control loop simultaneously and independently of the optical node, and wherein each of the optical node and the at least one additional node perform the control loop based only on their own measurements;
modify parameters of the control loop with a plurality of states to maintain a stable response; and
adjust power of the channel based on the modified control loop using the components to selectively alter the power.
14. The optical node of claim 13, wherein the power controller is further configured to:
modify the control loop to set a derivative coefficient to zero if an overshoot is detected in a previous iteration of the control loop.
15. The optical node of claim 13, wherein the power controller is further configured to:
modify the control loop to select coefficients in such a way that a response remains always damped until complete convergence.
16. The optical node of claim 13, wherein the power controller is further configured to:
perform the control loop initially with coefficients selected for a damped unit step response;
modify the control loop with a first damping factor once absolute magnitude of the measured error is below a first threshold when the optical node is not an ingress node for the channel; and
modify the control loop with a second damping factor once absolute magnitude of the measured error is below a second threshold when the optical node is not an ingress node for the channel.
17. The optical node of claim 13, wherein the at least one additional node performs the control loop in parallel with the optical node utilizing a same set of coefficients; and wherein the power controller is further configured to:
modify the control loop at the optical node with an expected error change offset to dampen a response due to variable input power from the at least one additional node.
18. The optical node of claim 13, wherein the power controller is further configured to:
determine a drive offset parameter for each iteration of the control loop to compensate for plant drift and aging effects.
19. The optical node of claim 13, wherein the channel comprises a first channel, and wherein the power controller is further configured to:
detect a second channel being added to the at least one degree; and
perform the measure, the determine, the perform, the modify, and the adjust steps with respect to the second channel independent of the first channel with independent parameters.
20. An optical network, comprising:
N nodes interconnected therebetween, wherein each of the N nodes comprises:
at least one degree comprising components configured to selectively modify power of a channel being added thereto;
an optical power monitor measuring a power of the channel at least one degree; and
a power controller communicatively coupled to the at least one degree and the optical power monitor; and

a channel being added to M nodes of the N nodes simultaneously, M <N;
wherein the power controller at each of the M nodes is configured to:
measure power of the channel through the at least one degree;
determine a measured error of the channel based on a target power and the measured power;
simultaneously and independently perform a control loop using the measured error, and wherein each of the M nodes perform the control loop based only on their own measurements;
modify parameters of the control loop with a plurality of states to maintain a stable response; and
adjust power of the channel based on the modified control loop using the components to selectively alter the power.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

What is claimed is:

1. An image predictive decoding method for decoding an input coded data by referring to a reference image including an object image comprising a luminance signal indicating a pixel value and a shape signal indicating whether a pixel is located inside or outside the object image, said method comprising:
obtaining a substitute pixel value for a pixel located outside the object image, which is determined according to the shape signal, in a subarea of the reference image by using a pixel value of a pixel located inside the object image, which is determined according to the shape signal, in the subarea of the reference image;
generating a padded predictive subarea by padding the pixel located outside the object image with the substitute pixel value;
decoding the input coded data to obtain a decoded difference data; and
adding the decoded difference data and the padded predictive subarea to generate a decoded image.
2. An image predictive decoding method according to claim 1, wherein the substitute pixel value is an average of pixel values of pixels located inside the object image, which is determined according to the shape signal.
3. An image predictive decoding apparatus for decoding an input coded data by referring to a reference image including an object image comprising a luminance signal indicating a pixel value and a shape signal indicating whether a pixel is located inside or outside the objectimage, said apparatus comprising:
a device operable to obtain a substitute pixel value for a pixel located outside the object image, which is determined according to the shape signal, in a subarea of the reference image by using a pixel value of a pixel located inside the object image, which is determined according to the shape signal, in the subarea of the reference image;
a device operable to generate a padded predictive subarea by padding the pixel located outside the object image with the substitute pixel value;
a device operable to decode the input coded data to obtain a decoded difference data; and
a device operable to add the decoded difference data and the padded predictive subarea to generate a decoded image.
4. An image predictive decoding apparatus according to claim 3, wherein the substitute pixel value is an average of pixel values of pixels located inside the object image, which is determined according to the shape signal.