1. A method of using an endoscope and a guide having an elongated body member with a handle at a proximal end to perform a colonoscopy in a colon, the method comprising the steps of:
a) inserting a tip of the endoscope into the colon through the anus;
b) advancing the endoscope in the colon;
c) withdrawing the endoscope to reduce or straighten a loop in the sigmoid colon;
d) introducing a distal end of the body member into the rectum generally along the endoscope with an inner side of said body member substantially adjacent or against the endoscope;
e) advancing the inner side of the body member along the endoscope;
f) tilting the body member of the guide to direct the endoscope towards the descending colon; and
g) advancing the endoscope against the body member in the colon to perform the colonoscopy.
2. The method according to claim 1 further comprising the step of:
h) repeating steps f) and g) as necessary upon formation of a subsequent loop in the sigmoid colon.
3. The method according to claim 1, wherein the tilting step is achieved by manipulating the handle.
4. The method according to claim 1, wherein the distal end of the body member has a curved cross-section configured to improve contact of the inner side with the endoscope.
5. The method according to claim 4, wherein the inner side of the body member is coated or lined with a liner material.
6. The method according to claim 5, wherein the liner material is coated or impregnated with a lubricant.
7. The method according to claim 1, wherein the inner side of the body member is coated or lined with a liner material.
8. The method according to claim 7, wherein the liner material is coated or impregnated with a lubricant.
9. The method of claim 1, wherein the inner side of the body member is coated or impregnated with a lubricant.
10. The method of claim 9, wherein the lubricant is a hydrophilic material.
11. The method of claim 1, wherein at least part of the body member is rigid.
12. The method according to claim 1, wherein the guide has an injection port generally at said proximal end of said body member on or near the handle, one or more discharge openings on the inner side of the body member and one or more channels interconnecting the injection port and the one or more discharge openings, the method further comprising the step of injecting a fluid onto the endoscope.
13. The method according to claim 1, wherein the guide further comprises a ring member integral with or attached to the body member, the ring member sized and configured to substantially encircle the endoscope.
14. The method according to claim 13, wherein the ring member comprises a slot configured to facilitate placement of the endoscope in the ring member prior to the introducing step and the method comprises the step of closing said slot prior to the introducing step.
15. The method according to claim 1, wherein the guide further comprises an elongated tube member at or near said distal end of the body member, the tube member integral with or attached to the body member.
16. The method according to claim 15, wherein the tube member extends substantially the entire length of the body member.
17. The method according to claim 16, wherein the tube member has graduated stiffness along its length, the distal end of the body member being generally more flexible than the proximal end thereof.
18. The method of claim 16, wherein the tube member is at least partially rigid.
19. A method of using an endoscope and a guide having an elongated body member with a handle at a proximal end and means for engaging the endoscope at or near a distal end to perform a colonoscopy in a colon, the method comprising the steps of:
a) inserting a tip of the endoscope into the colon through the anus;
b) advancing the endoscope in the colon;
c) with the tip of the endoscope in the sigmoid colon or beyond, withdrawing the endoscope to reduce or straighten a loop in the sigmoid colon;
d) placing the engaging means over the endoscope outside the anus;
e) introducing the distal end of the body member into the rectum generally along the endoscope with the endoscope disposed in the engaging means so as to place an inner side of the body member substantially adjacent to or abutting the endoscope;
f) advancing the inner side of the body member along the endoscope;
g) manipulating the handle to tilt the body member to direct the endoscope towards the descending colon; and
h) advancing the endoscope against the body member in the colon to perform the colonoscopy.
20. The method according to claim 19, wherein the engaging means comprises one or more ring members integral with or attached to the body member, each of the one or more ring members having a slot configured to receive the endoscope therein.
21. The method according to claim 20, wherein at least one of the one or more ring members is at the distal end of said body member.
22. The method according to claim 19, wherein the engaging means is a tube member integral with or attached to the body member at or near the distal end of the body member, the tube member having a slot configured to receive the endoscope therein.
23. The method according to claim 19, wherein the guide has an injection port generally at the proximal end of the body member on or near the handle, one or more discharge openings on the inner side of the body member and one or more channels interconnecting the injection port and the one or more discharge openings, the method further comprising the step of injecting a fluid onto the endoscope.
24. A method of using an endoscope and a guide having an elongated body member with a handle at a proximal end and means for engaging the endoscope at or near a distal end to perform a colonoscopy in a colon, the method comprising the steps of:
a) inserting the endoscope through the engaging means;
b) moving the guide towards the proximal end of the endoscope;
c) inserting a tip of the endoscope into the colon through the anus;
d) advancing the endoscope in the colon;
e) withdrawing the endoscope to reduce or straighten a loop in the sigmoid colon;
f) sliding the distal end of the body member to the anus;
g) introducing the body member into the rectum generally along the endoscope with the endoscope disposed in the engaging means to place an inner side of the body member substantially adjacent to or against the endoscope;
h) advancing the inner side of the body member along the endoscope;
i) manipulating the handle to tilt the body member to direct the endoscope towards the descending colon; and
j) advancing the endoscope against the body member through the colon to perform the colonoscopy.
25. The method according to claim 24, wherein the engaging means is one or more ring members integral with or attached to the body member.
26. The method according to claim 24, wherein the engaging means is a tube member integral with or attached to the body member at or near the distal end of the body member.
27. The method according to claim 24, wherein the colonoscope guide has an injection port generally at the proximal end of the body member on or near the handle, the method further comprising the step of injecting a fluid onto the endoscope through the injection port.
28. A method of using an endoscope and a guide having an elongated body member with a handle at a proximal end and means for engaging the endoscope at or near a distal end to perform a colonoscopy in a colon, the method comprising the steps of:
a) inserting the body member of the guide into the colon through the anus;
b) inserting a tip of the endoscope into the colon through the anus;
c) tilting the body member to direct the endoscope towards the descending colon; and
d) advancing the endoscope in the colon against an inner side of the body member to perform the colonoscopy.
29. The method according to claim 28 further comprising the step of:
e) withdrawing the endoscope to reduce or straighten a loop in the sigmoid colon while maintaining the body member against the endoscope so as to generally align the rectum with the descending colon;
f) advancing the endoscope to perform the colonoscopy; and
g) repeating steps e) and f) as necessary upon formation of a subsequent loop in the sigmoid colon.
30. The method according to claim 28, wherein the guide further comprises an elongated tube member extending substantially the entire length of the body member, the tube member integral with or attached to the body member.
31. The method of claim 30, wherein the tube member is at least partially rigid.
32. The method according to claim 30, wherein the tube member has graduated stiffness along its length, the distal end of the body member being generally more flexible than the proximal end thereof.
33. The method according to claim 28, wherein the colonoscope guide has an injection port generally at the proximal end of the body member on or near the handle, one or more discharge openings on the inner side of the body member and one or more channels interconnecting the injection port and the one or more discharge openings, the method further comprising the step of injecting a fluid onto the endoscope.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An assay device for a sample of bodily fluid containing at least one of a plurality of analytes selected for determining its presence, the device comprising:
a sample receptor for receiving the sample, the sample receptor being located on the exterior surface of a device housing and allowing the sample to be applied to a transport matrix; and
chemically reacting the clean with at least one chemical reagent corresponding to an assay located on the transport matrix, each reagent chemically reacts with the sample in a corresponding reaction zone located on the transport matrix to produce a reaction product mixture corresponding to each reagent.