1. A compound of the formula:
wherein:
Y is hydroxy or NR1R2, wherein:
R1 and R2 are independently:
hydrogen or hydroxy; or
alkyl(C\u226612), alkenyl(C\u226612), alkynyl(C\u226612), aryl(C\u226612), aralkyl(C\u226612), heteroaryl(C\u226612), heteroaralkyl(C\u226612), acyl(C\u226612), alkoxy(C\u226612), alkenyloxy(C\u226612), alkynyloxy(C\u226612), aryloxy(C\u226612), aralkoxy(C\u226612), heteroaryloxy(C\u226612), heteroaralkoxy(C\u226612), thioacyl(C\u226612), alkylsulfonyl(C\u226612), alkenylsulfonyl(C\u226612), alkynylsulfonyl(C\u226612), arylsulfonyl(C\u226612), aralkylsulfonyl(C\u226612), heteroarylsulfonyl(C\u226612), or heteroaralkylsulfonyl(C\u226612), or a substituted version of any of these groups;
or pharmaceutically acceptable salts, tautomers, or optical isomers thereof.
2. The compound of claim 1, further defined as:
wherein:
R1 and R2 are independently:
hydrogen; or
alkyl(C\u226612), alkenyl(C\u226612), alkynyl(C\u226612), aryl(C\u226612), aralkyl(C\u226612), heteroaryl(C\u226612), heteroaralkyl(C\u226612), acyl(C\u226612), alkylsulphonyl, alkenylsulphonyl(C\u226612), alkynylsulphonyl(C\u226612), arylsulphonyl(C\u226612), aralkylsulphonyl(C\u226612), heteroarylsulphonyl(C\u226612), heteroaralkylsulphonyl(C\u226612), or a substituted version of any of these groups;
or pharmaceutically acceptable salts, tautomers, or optical isomers thereof.
3. The compound of claim 2, wherein the bond joining carbon 9 and carbon 11 is a double bond.
4. The compound of claim 2, wherein the bond joining carbon 9 and carbon 11 is a single bond.
5. The compound of claim 2, further defined as:
6. A compound of the formula:
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A cover for covering at least part of a pen in stables for domestic animals, wherein the cover includes:
means for fastening a rear edge of the cover to a side of the pen, where the means allow turning of the cover in relation to the side of the pen;
one or more sensors mounted at the bottom side or top side of the cover or at a bracket fastened to a wall, where the sensors are heat sensors, including particularly infrared temperature sensors andor where the sensors are a number of CO2 sensors;
means for elevating andor lowering the front edge of the cover opposite the rear edge where the cover is fastened to the side;
a control which receives input from the sensors and which on the basis of predefined parameters activates the means for elevating andor lowering the edge of the cover.
2. Cover according to claim 1, wherein the means for elevating andor lowering the front edge of the cover include wires connected to the cover at one end and to a motor at a second end, and that wires optionally may be coupled from other covers in other pens to the same motor, where the motor is controlled by the control.
3. Cover according to claim 1, wherein the control furthermore controls a number of heating elements which may adjust the temperature under the cover.
4. A method for regulating the climate in an area of an animal stable with a cover according to claim 1, the cover being arranged at least over a part area in a double climate pen in stables for domestic animals, where sensors are arranged in connection with a control, where the sensors are heat sensors, including particularly infrared temperature sensors suited for detecting the surface temperature of the animals in the covered area, andor where the sensors are a number of CO2 sensors suited for detecting the CO2 concentration under the cover, so that the detected temperature or temperatures andor the CO2 concentrations are input parameters for the control, where the input parameters are compared with predefined limits, and wherein the control generates an output in case of input lying outside the predefined limits, causing the front edge of the cover to be lowered or elevated, respectively, where the front edge of the cover can be lowered to such a low level that the heat loss to the stable corresponds to the heat emission of the animals in their sleeping condition andor to a predetermined CO2 concentration level, and where the front edge of the cover is elevated when the animals do not sleep and thereby produce more heat.
5. Method according to claim 4, wherein the lowermost position of the front edge may be increased by the age of the animals.
6. Method according to claim 4, wherein the air temperature in the stable may be increased when too low temperature is detected under the cover, and vice versa.
7. Method according to claim 4, wherein heat is supplied under the cover when too low surface temperature is detected at the animals, the cover at the same time being at its lowermost position.
8. Method according to claim 4, wherein an inspection function may be activated whereby the cover is lifted to a previously determined position that allows a free view to all animals.
9. Method according to claim 4, wherein the lowermost position may also be determined by the content of CO2 in the air under the cover andor in the stable.