1. An isolated polynucleotide comprising a nucleotide sequence which hybridizes under stringent conditions to a sequence selected from the group consisting of SEQ ID NOS: 1-6010.
2. An isolated polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence having at least 90% sequence identity to a sequence selected from the group consisting of:
SEQ ID NOS: 1-6010, a degenerate variant of SEQ ID NOS: 1-6010, an antisense of SEQ ID NOS: 1-6010, and a complement of SEQ ID NOS: 1-6010.
3. An isolated polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence selected from the group consisting of: SEQ ID NOS:1-6010, a degenerate variant of SEQ ID NOS:1-6010, an antisense of SEQ ID NOS:1-6010, and a complement of SEQ ID NOS: 1-6010.
4. The isolated polynucleotide of claim 3, wherein the polynucleotide comprises at least 100 contiguous nucleotides of the nucleotide sequence.
5. The isolated polynucleotide of claim 3, wherein the polynucleotide comprises at least 200 contiguous nucleotides of the selected nucleotide sequence.
6. An isolated polynucleotide comprising a nucleotide sequence of at least 90% sequence identity to a sequence selected from the group consisting of: SEQ ID NOS: 1-6010, a degenerate variant of SEQ ID NOS:1-6010, an antisense of SEQ ID NOS:1-6010, and a complement of SEQ ID NOS:1-6010.
7. The isolated polynucleotide of claim 6, wherein the polynucleotide comprises a nucleotide sequence of at least 95% sequence identity to the selected nucleotide sequence.
8. The isolated polynucleotide of claim 6, wherein the polynucleotide comprises a nucleotide sequence that is identical to the selected nucleotide sequence.
9. A polynucleotide comprising a nucleotide sequence of an insert contained in a clone deposited as ATCC Accession No. PTA-2027, PTA-2028, PTA-2029, PTA-2030, PTA-2031, PTA-2032, PTA-2033, PTA-2034, PTA-2035, PTA-2036, PTA-2037, PTA-2038, PTA-2039, PTA-2040, PTA-2041, PTA-2042, PTA-2043, PTA-2044, PTA-2045, PTA-2046, PTA-2047, PTA-2050, PTA-2051, PTA-2052, PTA-2053, PTA-2054, PTA-2055, PTA-2056, PTA-2057, PTA-2058, PTA-2059, PTA-2060, PTA-2061, PTA-2062, PTA-2048, PTA-2049, PTA-2063, PTA-2064, PTA-2065, PTA-2066, PTA-2067, or PTA-2068.
10. An isolated cDNA obtained by the process of amplification using a polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence of a sequence selected from the group consisting of SEQ ID NOS: 1-6010.
11. The isolated cDNA of claim 10, wherein the polynucleotide comprises at least 25 contiguous nucleotides of the selected nucleotide sequence.
12. The isolated cDNA of claim 10, wherein the polynucleotide comprises at least 100 contiguous nucleotides of the selected nucleotide sequence.
13. The isolated cDNA of claims 10, 11, or 12, wherein amplification is by polymerase chain reaction (PCR) amplification.
14. An isolated recombinant host cell containing the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
15. An isolated vector comprising the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
16. A method for producing a polypeptide, the method comprising the steps of:
culturing a recombinant host cell containing the polynucleotide according to claims 1, 2, 3, 6, 9, or 10., said culturing being under conditions suitable for the expression of an encoded polypeptide;
recovering the polypeptide from the host cell culture.
17. An isolated polypeptide encoded by the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
18. An antibody that specifically binds the polypeptide of claim 17.
19. A method of detecting differentially expressed genes correlated with a cancerous state of a mammalian cell, the method comprising the step of:
detecting at least one differentially expressed gene product in a test sample derived from a cell suspected of being cancerous, where the gene product is encoded by a gene comprising an identifying sequence of at least one of SEQ ID NOS: 1-6010;
wherein detection of the differentially expressed gene product is correlated with a cancerous state of the cell from which the test sample was derived.
20. A library of polynucleotides, wherein at least one of the polynucleotides comprises the sequence information of the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
21. The library of claim 20, wherein the library is provided on a nucleic acid array.
22. The library of claim 20, wherein the library is provided in a computer-readable format.
23. A method of inhibiting tumor growth by modulating expression of a gene product, the gene product being encoded by a gene identified by a sequence selected from the group consisting of SEQ ID NOS:1-6010.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A portable data storage device with USB accessible biometrics processor comprising:
an embedded fingerprint biometrics processing unit and sensor, wherein the fingerprint biometrics processing unit is accessible externally by USB host and internally within the device;
a plurality of non-volatile solid state readwrite memories for data and information storage;
a processor unit for interfacing with the embedded fingerprint system, a USB host and the non-volatile solid state readwrite memories;
a data encryption or a data protection scheme for data and information safekeeping within the non-volatile solid state readwrite memories; and
an enrollment scheme for biometric fingerprint enrollment.
2. The portable data storage device of claim 1, wherein the authorization access to the data storage is only by authorized fingerprints.
3. The portable data storage device as in claim 1, wherein a micro-controller and the embedded fingerprint biometric processing unit within the device are employed so as to authorize the read and write access of the non-volatile solid state readwrite memories.
4. The portable data storage device of claim 1, wherein bio-data for authentication of any unauthorized access to the non-volatile solid state readwrite memories is stored within the device.
5. The portable data storage device of claim 4, wherein the bio-data is inaccessible by the USB host.
6. The portable data storage device of claim 4, wherein users fingerprint bio-data include master fingerprint bio-data and normal user fingerprint bio-data, and the master user is able to erase the bio-data of both the master and the normal user, while the normal user is only able to erase his own bio-data.
7. The portable data storage device of claim 1, wherein an enrollment switch is used to differentiate fingerprint enrollment and normal device authentication operation.
8. A method of using a biometric parameters protected portable data storage device, said method comprising the steps of:
scanning user’s fingerprint by a fingerprint sensor;
processing the scanned fingerprint image by a biometrics processing unit which verifies the image with the user(s) fingerprint bio-data which is in a bio-data storage unit; and
requesting another fingerprint for scanning again from the user if the verification fails.
9. The portable data storage device of claim 1, wherein the typical biometrics verification and system access time is not more than 1 second.
10. The portable data storage device of claim 1, wherein the biometrics enrollment time is not more than 1 second per user, and not more than 10 users are assigned for authority access right.
11. The portable data storage device of claim 1, wherein the memories of the nonvolatile solid stage readwrite memories include flash memories.
12. The portable data storage device of claim 11, wherein the memories of the nonvolatile solid stage readwrite memories are magneto-resistive random access memories commonly (MRAM).
13. The portable data storage device as in claim 2, wherein a micro-controller and the embedded fingerprint biometric processing unit within the device are employed so as to authorize the read and write access of the non-volatile solid state readwrite memories.
14. The portable data storage device of claim 2, wherein bio-data for authentication of any unauthorized access to the non-volatile solid state readwrite memories is stored within the device.