1. A method for use with an implantable medical device for implant within a patient, the method comprising:
detecting a plurality of cardiogenic impedance signals along different sensing vectors within the patient;
detecting a measure of mechanical dyssynchrony in the heart of the patient based on a comparison of the cardiogenic impedance signals, including detecting abnormally contracting segments, if any, within the heart of the patient; and
controlling at least one device function based on the measure of mechanical dyssynchrony.
2. The method of claim 1 wherein detecting the plurality of cardiogenic impedance signals includes detecting individual cardiac impedance signals by:
measuring a raw impedance signal along a selected sensing vector passing through the heart of the patient; and
extracting a cardiogenic impedance signal (CI) from the raw impedance signal, wherein the cardiogenic impedance (CI) signal is representative of variations in impedance due to the beating of the heart of the patient.
3. The method of claim 1 wherein detecting the measure of mechanical dyssynchrony includes detecting differences among the cardiogenic impedance signals.
4. The method of claim 3 wherein detecting differences among the cardiogenic impedance signals includes detecting differences in peak magnitude delay times observed within the cardiogenic impedance signals.
5. The method of claim 4 wherein detecting differences in peak magnitude delay times includes:
delivering a pacing pulse to the heart of the patient;
for each of the cardiogenic impedance signals, examining the signal to detect a maximum in the signal after pulse delivery and then measuring the time delay from the pulse to the maximum in the signal; and
comparing the peak magnitude delay times derived from the cardiogenic impedance signals to generate the measure of mechanical dyssynchrony.
6. The method of claim 4 wherein significant differences in the peak magnitude delay times are representative of significant mechanical dyssynchronies within the heart.
7. The method of claim 4 further including identifying late contracting segments within the heart of the patient by identifying particular cardiogenic impedance signals wherein the peak magnitude delay time is significantly longer than the peak magnitude delay times of the other cardiogenic impedance signals.
8. The method of claim 3 wherein detecting differences among the cardiogenic impedance signals includes detecting differences in peak velocity delay times observed within the cardiogenic impedance signals.
9. The method of claim 8 wherein detecting differences in peak velocity delay times includes:
delivering a pacing pulse to the heart of the patient;
for each of the cardiogenic impedance signals, examining the signal to detect a maximum in a first time derivative of the signal after pulse delivery and then measuring the time delay from the pulse to the maximum in the first time derivative; and
comparing the peak velocity delay times derived from the cardiogenic impedance signals to generate the measure of mechanical dyssynchrony.
10. The method of claim 8 wherein significant differences in the peak velocity delay times are representative of significant mechanical dyssynchronies within the heart.
11. The method of claim 8 further including identifying late contracting segments within the heart of the patient by identifying particular cardiogenic impedance signals wherein the peak velocity delay time is significantly longer than the peak velocity delay times of the other cardiogenic impedance signals.
12. The method of claim 3 wherein detecting differences among the cardiogenic impedance signals includes detecting differences in peak magnitudes observed within the cardiogenic impedance signals.
13. The method of claim 12 wherein detecting differences in peak magnitudes includes:
delivering a pacing pulse to the heart of the patient;
for each of the cardiogenic impedance signals, examining the signal to detect a maximum magnitude of the signal after pulse delivery; and
comparing the peak magnitudes derived from the cardiogenic impedance signals to generate the measure of mechanical dyssynchrony.
14. The method of claim 12 wherein significant differences in the peak magnitudes are representative of significant mechanical dyssynchronies within the heart.
15. The method of claim 12 further including identifying hypokinetic segments within the heart of the patient by identifying cardiogenic impedance signals with peak magnitudes significantly lower than the peak magnitudes of the other cardiogenic impedance signals.
16. The method of claim 12 further including identifying akinetic segments within the heart of the patient by identifying cardiogenic impedance signals with peak magnitudes below a minimum acceptable magnitude threshold.
17. The method of claim 3 wherein detecting differences among the cardiogenic impedance signals includes detecting differences in integrals derived from the cardiogenic impedance signals.
18. The method of claim 17 wherein detecting differences in the cardiogenic impedance signal integrals includes:
delivering a pacing pulse to the heart of the patient;
for each of the cardiogenic impedance signals, integrated a portion of the signal detected after pulse delivery; and
comparing the integrals derived from the cardiogenic impedance signals to generate the measure of mechanical dyssynchrony.
19. The method of claim 17 wherein significant differences in the cardiogenic impedance signal integrals are representative of significant mechanical dyssynchronies within the heart.
20. The method of claim 17 further including identifying hypokinetic segments within the heart of the patient by identifying cardiogenic impedance signals with integrals significantly smaller than the integrals of the other cardiogenic impedance signals.
21. The method of claim 17 further including identifying akinetic segments within the heart of the patient by identifying cardiogenic impedance signals with integrals below a minimum acceptable integral threshold.
22. The method of claim 1 wherein detecting abnormally contracting segments includes detecting one or more of akinetic segments, hypokinetic segments and late contracting segments.
23. The method of claim 1 wherein controlling at least one device function based on the measure of mechanical dyssynchrony includes one or more of: recording diagnostic information, generating warning signals, and controlling delivery of therapy.
24. The method of claim 1 wherein the steps are all performed by the implantable medical device.
25. The method of claim 1 wherein some of the steps are performed by the implantable medical device and others are performed by an external system.
26. A system for use with an implantable medical device for implant within a patient, the system comprising:
a multiple cardiogenic impedance signal detector operative to detect a plurality of cardiogenic impedance signals along different sensing vectors within the patient; and
a mechanical dyssynchrony evaluation system operative to detect a measure of mechanical dyssynchrony in the heart of the patient based on a comparison of the cardiogenic impedance signals, including detecting abnormally contracting segments, if any, within the heart of the patient.
27. The system of claim 26 further comprising:
a controller operative to control at least one device function based on the measure of mechanical dyssynchrony.
28. The system of claim 27 wherein the controller includes a mechanical dyssynchrony-based cardiac resynchronization therapy (CRT) controller operative to control CRT based, at least in part, on the measure of mechanical dyssynchrony.
29. The system of claim 27 wherein the controller includes a mechanical dyssynchrony-based warning controller operative to control the generation of warning signals in response to an increase in mechanical dyssynchrony.
30. A method for use with an implantable medical device for implant within a patient, the method comprising:
detecting a plurality of cardiogenic impedance signals along different sensing vectors within the patient;
detecting a measure of mechanical dyssynchrony in the heart of the patient based on a comparison of the cardiogenic impedance signals, including detecting differences in one or more of peak magnitude delay times of the cardiogenic impedance signals, peak velocity delay times of the cardiogenic impedance signals, peak magnitudes of the cardiogenic impedance signals, and integrals of the cardiogenic impedance signals; and
controlling at least one device function based on the measure of mechanical dyssynchrony.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A heat dissipating system comprising:
a housing including first and second boards between which a compartment is defined, with a partitioning board mounted in the compartment and dividing the compartment into first and second air channels, with the partitioning board including an opening through which the first air channel is in communication with the second air channel, with the partitioning board being a printed circuit board and including a plurality of electronic elements located in the first and second air channels;
a driving unit mounted in the first air channel, with the driving unit including a rotating shaft extending through the opening into the second air channel;
a first impeller mounted in the first air channel and coupled to the rotating shaft and aligned with the opening; and
a second impeller mounted in the second air channel and coupled to the rotating shaft and aligned with the opening, with some of the plurality of electronic elements located within a maximum outer diameter of the first impeller.
2. The heat dissipating system as claimed in claim 1, with each of the first and second impellers including a hub and a plurality of blades mounted on an outer periphery of the hub.
3. The heat dissipating system as claimed in claim 2, with the opening having a diameter larger than an outer diameter of the hub of the first impeller.
4. The heat dissipating system as claimed in claim 3, with the diameter of the opening larger than an outer diameter of the hub of the second impeller.
5. The heat dissipating system as claimed in claim 2, with the first board including a first air inlet in communication with the second air channel and aligned with the opening and the first and second impellers.
6. The heat dissipating system as claimed in claim 5, with a diameter of the first air inlet larger than an outer diameter of the hub of the second impeller.
7. The heat dissipating system as claimed in claim 5, with the second board including a second air inlet in communication with the first air channel and within a maximum diameter of the first impeller.
8. The heat dissipating system as claimed in claim 5, with the first and second impellers being of a blower type.
9. The heat dissipating system as claimed in claim 1, with the second impeller extending into the opening and being of an axial-flow type.
10. The heat dissipating system as claimed in claim 9, with the first impeller being of a blower type, with a maximum outer diameter of the first impeller being larger than the opening and a maximum outer diameter of the second impeller.
11. The heat dissipating system as claimed in claim 1, with the diameter of the opening not smaller than a maximum outer diameter of the second impeller.