1. A method for controlling an operation of a wind farm comprising a plurality of wind turbines, the method comprising
defining a setpoint vector, wherein each component of the setpoint vector represents an individual power setpoint of one of the plurality of wind turbines;
determining a dependency matrix, which reflects a desired power generation distribution between different wind turbines of the plurality of wind turbines;
calculating a power reference vector by multiplying the dependency matrix with the setpoint vector, such that the power reference vector comprises a coordinated power setpoint for each wind turbine; and
controlling the operation of the wind farm based on the calculated power reference vector,
wherein calculating the power reference vector further comprises adding a correction vector to the result of multiplying the dependency matrix with the setpoint vector, and
wherein the correction vector comprises a power correction value for each wind turbine, whereby each power correction value is indicative for a requested time rate of change of the total power output of the wind farm.
2. The method as set forth in claim 1, wherein each individual power setpoint is determined based on an individual nominal power output of the respective wind turbine and a requested total power output of the whole wind farm.
3. The method as set forth in claim 2, wherein a sum of all individual power setpoints corresponds to the requested total power output of the whole wind farm.
4. The method as set forth in claim 1, wherein each power correction value is proportional to the time derivative of the requested total power output of the wind farm.
5. The method as set forth in claim 4, wherein each power correction value is proportional to the negative time derivative of the requested total power output of the wind farm.
6. The method as set forth in claim 1, wherein at least one element of the dependency matrix depends on a type of operation of at least one wind turbine.
7. A superordinate control system for controlling the operation of a wind farm comprising a plurality of wind turbines, the superordinate control system comprising
a definition unit for defining a setpoint vector, wherein each component of the setpoint vector represents an individual power setpoint of one of the plurality of wind turbines;
a determination unit for determining a dependency matrix, which reflects a desired power generation distribution between different wind turbines of the plurality of wind turbines;
a calculation unit for calculating a power reference vector by multiplying the dependency matrix with the setpoint vector, such that the power reference vector comprises a coordinated power setpoint for each wind turbine; and
a control unit for controlling the operation of the wind farm based on the calculated power reference vector,
wherein calculating the power reference vector further comprises adding a correction vector to the result of multiplying the dependency matrix with the setpoint vector, and
wherein the correction vector comprises a power correction value for each wind turbine, whereby each power correction value is indicative for a requested time rate of change of the total power output of the wind farm.
8. The superordinate control system as set forth in claim 7, further comprising a computer-readable medium on which there is stored a computer program which when being executed by a data processor is adapted for controlling the operation of a plurality of wind turbines.
9. A wind farm for generating electric power, the wind farm comprising
a plurality of wind turbines each comprising an individual control unit for controlling the operation of the respective wind turbine; and
a superordinate control system for controlling the operation of a wind farm comprising a plurality of wind turbines, the superordinate control system comprising:
a definition unit for defining a setpoint vector, wherein each component of the setpoint vector represents an individual power setpoint of one of the plurality of wind turbines,
a determination unit for determining a dependency matrix, which reflects a desired power generation distribution between different wind turbines of the plurality of wind turbines,
a calculation unit for calculating a power reference vector by multiplying the dependency matrix with the setpoint vector, such that the power reference vector comprises a coordinated power setpoint for each wind turbine, and
a control unit for controlling the operation of the wind farm based on the calculated power reference vector,
wherein the superordinate control system is connected to each individual control unit,
wherein calculating the power reference vector further comprises adding a correction vector to the result of multiplying the dependency matrix with the setpoint vector, and
wherein the correction vector comprises a power correction value for each wind turbine, whereby each power correction value is indicative for a requested time rate of change of the total power output of the wind farm.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A composition comprising a water-miscible organic solvent, a cyclodextrin derivative and a compound, wherein the composition contains 10 wt % or less water.
2. The composition of claim 1, wherein the composition contains 5 wt % or less water.
3. The composition of claim 1, wherein the composition contains 2 wt % or less water.
4. The composition of claim 1, wherein the cyclodextrin derivative comprises a hydroxybutenyl cyclodextrin.
5. The composition of claim 4, wherein the hydroxybutenyl cyclodextrin comprises hydroxybutenyl-\u03b2-cyclodextrin.
6. The composition of claim 4, wherein the hydroxybutenyl cyclodextrin comprises a sulfonated hydroxybutenyl cyclodextrin.
7. The composition of claim 6, wherein the sulfonated hydroxybutenyl cyclodextrin comprises sulfonated hydroxybutenyl-\u03b2-cyclodextrin.
8. The composition of claim 1, wherein the water-miscible organic solvent comprises a natural polymer, a synthetic polymer, a semisynthetic polymer, an alcohol, a polyol, or a mixture thereof.
9. The composition of claim 1, wherein the water-miscible organic solvent comprises polyethylene glycol, ethanol, propylene glycol, glycerin, or a mixture thereof.
10. The composition of claim 1, wherein the compound comprises a pharmaceutically active compound or salt, structural analog or metabolite thereof.
11. A composition comprising a water-miscible organic solvent, a cyclodextrin derivative and a compound, wherein the water-miscible organic solvent contains 10 wt % or less water.
12. The composition of claim 11, wherein the water-miscible organic solvent contains 5 wt % or less water.
13. The composition of claim 11, wherein the water-miscible organic solvent contains 2 wt % or less water.
14. The composition of claim 11, wherein the cyclodextrin derivative comprises a hydroxybutenyl cyclodextrin.
15. The composition of claim 14, wherein the hydroxybutenyl cyclodextrin comprises hydroxybutenyl-\u03b2-cyclodextrin.
16. The composition of claim 14, wherein the hydroxybutenyl cyclodextrin comprises a sulfonated hydroxybutenyl cyclodextrin.
17. The composition of claim 16, wherein the sulfonated hydroxybutenyl cyclodextrin comprises sulfonated hydroxybutenyl-\u03b2-cyclodextrin.
18. The composition of claim 11, wherein the water-miscible organic solvent comprises a natural polymer, a synthetic polymer, a semisynthetic polymer, an alcohol, a polyol, or a mixture thereof.
19. The composition of claim 11, wherein the water-miscible organic solvent comprises polyethylene glycol, ethanol, propylene glycol, glycerin, or a mixture thereof.
20. The composition of claim 11, wherein the compound comprises a pharmaceutically active compound or salt, structural analog or metabolite thereof.
21. A method of enhancing the solubility of a compound in aqueous media comprising forming a mixture or complex between the compound and a cyclodextrin derivative in a water-miscible organic solvent, wherein the mixture or complex contains 10 wt % or less water.
22. A method of increasing the bioavailability of a compound in a subject comprising administering the composition of claim 1 to the subject.
23. The method of claim 22, wherein the subject is a human.
24. A method of increasing the bioavailability of a compound in a subject comprising administering the composition of claim 11 to the subject.
25. The method of claim 24, wherein the subject is a human.